Capaldi
Carmelida Capaldi, Parma IT
Patent application number | Description | Published |
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20130005716 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS - Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme and the treatment of certain conditions such as COPD. | 01-03-2013 |
20130065913 | NOVEL COMPOUNDS - Compounds of formula (I): | 03-14-2013 |
20130079313 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS - The invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to compounds that are derivatives of 1-phenyl-2-pyridinyl alkyl alcohols, methods of preparing such compounds, compositions containing them and therapeutic use thereof. | 03-28-2013 |
20130102576 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS - Compounds, pyridine N-oxides, and pharmaceutically acceptable salts of formula (I) are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme and for preventing and/or treating diseases of the respiratory tract characterized by airway obstruction, such as asthma or COPD. | 04-25-2013 |
20130324501 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS - Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols according to formula (I) are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme. | 12-05-2013 |
20140018345 | INHIBITION OF ENZYMES - Compounds of formula (I): | 01-16-2014 |
20140057882 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS - Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme and the treatment of certain conditions such as COPD. | 02-27-2014 |
20140142074 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS - The invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to compounds that are derivatives of 1-phenyl-2-pyridinyl alkyl alcohols, methods of preparing such compounds, compositions containing them and therapeutic use thereof. | 05-22-2014 |
20140155391 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS - Compounds of formula (I) described herein are inhibitors of the phosphodiesterase 4 (PDE4) enzyme and are useful for the prevention and/or treatment of an allergic disease state or a disease of the respiratory tract characterized by airway obstruction. | 06-05-2014 |
20140171414 | NOVEL COMPOUNDS - Compounds of formula (I) defined herein exhibit human neutrophil elastase inhibitory properties and are useful for treating diseases and conditions in which HNE is implicated. | 06-19-2014 |
20140179714 | NOVEL COMPOUNDS - Compounds of formula (I): | 06-26-2014 |
20140364411 | KINASE INHIBITORS - Compounds of formula (I) described herein are p38 MAPK inhibitors and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract. | 12-11-2014 |
Daniel Capaldi, Carlsbad, CA US
Patent application number | Description | Published |
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20090095896 | METHODS FOR DETECTION, IDENTIFICATION AND QUANTIFICATION OF IMPURITIES - Provided is a method comprising introducing a sample comprising a plurality of oligonucleotides into an ion pair high performance liquid chromatography column having a buffered mobile phase and allowing at least a portion of the oligonucleotides to separate; allowing the oligonucleotides to elute from the column; and introducing the oligonucleotides into a mass spectrometer and quantifying at least a portion of the oligonucleotides by mass spectrometry. In the method, at least a portion of the oligonucleotides are co-eluting oligonucleotides that differ in mass by no more than 20%; and the buffered mobile phase causes at least 50 mole percent of co-eluting oligonucleotides to have the same charge when they enter the mass spectrometer. | 04-16-2009 |
Franco Capaldi, Andover, MA US
Patent application number | Description | Published |
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20140162236 | INTERACTIVE ASSIGNMENT SYSTEM INCLUDING A SIMULATION SYSTEM FOR SIMULATING MODELS OF PROBLEMS - An interactive assignment system to present problems to users. The interactive assignment system may include a simulation system to simulate interactions of objects of a model of the problem. The simulation system may be configured to determine characterizations of properties of the model based on simulating the interactions. The interactive assignment system may enable users to input a characterization of a property of the model, and the simulation system may determine a correct characterization from evaluating the model. The users' input may then be compared to the correct characterization to determine whether the users' input is correct. Similarly, the interactive assignment system may enable a user configuring a problem (such as an instructor for a course) merely to indicate a property of the model to which a desired solution relates, and the simulation system may determine a correct characterization of the property from evaluating the model. | 06-12-2014 |
20140162237 | INTERACTIVE ASSIGNMENT SYSTEM INCLUDING A SIMULATION SYSTEM FOR SIMULATING MODELS OF PROBLEMS - An interactive assignment system to present problems to users. The interactive assignment system may include a simulation system to simulate interactions of objects of a model of the problem. The simulation system may be configured to determine characterizations of properties of the model based on simulating the interactions. The interactive assignment system may enable users to input a characterization of a property of the model, and the simulation system may determine a correct characterization from evaluating the model. The users' input may then be compared to the correct characterization to determine whether the users' input is correct. Similarly, the interactive assignment system may enable a user configuring a problem (such as an instructor for a course) merely to indicate a property of the model to which a desired solution relates, and the simulation system may determine a correct characterization of the property from evaluating the model. | 06-12-2014 |
Guido Capaldi, Farmington, MI US
Patent application number | Description | Published |
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20120159706 | PATIENT LIFTING DEVICE - The patient lifting device includes a transverse beam that supports a movable lift assembly to move a patient relative to at least one of a bed or chair. The transverse beam spans between a pair of support structures and allows the lift assembly to move horizontally along the transverse beam to move the patient horizontally relative to the bed or chair. At one of the transverse beam ends, the lift assembly contacts a charging station. The charging station charges a battery, that is carried by the lift assembly, to power the lift assembly. The lift assembly is powered to move a patient vertically upward and downward. A power source is electrically coupled to the charging station to provide electrical power to charge the battery of the lift assembly through the charging station. | 06-28-2012 |
Michael Capaldi, Malvern, PA US
Patent application number | Description | Published |
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20090171072 | Process for Preparing Unaggregated Antibody FC Domains - Methods useful for producing a solution of purified Fc peptide chains are disclosed. The methods employ protein A chromatography to separate high molecular weight, aggregated peptide chains comprising antibody Fc domains from lower molecular weight unaggregated peptide chains that also comprise antibody Fc domains. The solutions of purified Fc peptide chains obtained by the methods of the invention contain less than 5% aggregate and greater than 70% of the Fc peptide chains subjected to purification. | 07-02-2009 |