Oehme, DE
Bernd Oehme, Mainz DE
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20150140504 | SOFT-TISSUE LASER SURGERY - In dentistry very often soft tissue has to be cut. It has become customary to cut soft tissue, in particular gum or gingiva, or to disinfect pockets in the gingiva that exist at the neck of teeth with the help of laser light. The same applies to a disinfection of the channel in the root of teeth (endodontic treatment). Prior art concepts of cutting soft tissue rely on the use of red or infrared diode lasers and lead to an excessive heating the tissue and damaging of surrounding tissue. We suggest a device for treatment comprising a laser diode with a wavelength of 445±15 nm, in particular 445±10 nm, for providing the laser light. The use of e.g. 445 nm for cutting soft tissues has numerous advantages. | 05-21-2015 |
Felix Oehme, Wuppertal DE
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20090170766 | Chimeric Kunitz Domains and their Use - The present invention relates to chimeras of human tissue factor inhibitor domain 1 with natural and non-natural Kunitz domains, and their preparation and use. | 07-02-2009 |
20100035906 | Dipyridyl-dihydropyrazolones and their use - The present application relates to novel dipyridyl-dihydropyrazolones, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing. | 02-11-2010 |
20100093803 | SUBSTITUTED DIPYRIDYL-DIHYDROPYRAZOLONES AND USE THEREOF - The present application relates to novel substituted dipyridyldihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing. | 04-15-2010 |
20100305085 | SUBSTITUTED DIHYDROPYRAZOLONES FOR TREATING CARDIOVASCULAR AND HEMATOLOGICAL DISEASES - The invention relates to dihydropyrazolon-derivatives of formula (I), to methods for their production, to their use for treating and/or for preventing diseases and their use for producing medicaments for treating and/or for preventing diseases, in particular cardiovascular and haematological diseases, kidney diseases and for promoting the healing of wounds. | 12-02-2010 |
20120121727 | SUBSTITUTED DIHYDROPYRAZOLONES FOR TREATING CARDIOVASCULAR AND HEMATOLOGICAL DISEASES - The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing. | 05-17-2012 |
20120264704 | SUBSTITUTED DIHYDROPYRAZOLONES AND USE THEREOF AS HIF-PROLYL-4 -HYDROXYLASE INHIBITORS - The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing. | 10-18-2012 |
20120322772 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES - The present application relates to novel dipyridyl-dihydropyrazolones, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing. | 12-20-2012 |
20140031329 | SUBSTITUTED DIHYDROPYRAZOLONES FOR TREATING CARDIOVASCULAR AND HEMATOLOGICAL DISEASES - The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing. | 01-30-2014 |
Felix Frederik Oehme, Hamburg DE
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20140349214 | Device For Cooling And Dehumidifying Gases, Method For Cooling And Dehumidifying Gases, And Vehicle With A Fuel Cell System And A Device For Cooling And Dehumidifying Fuel Cell Exhaust Air - A device for cooling and dehumidifying gases includes a first hollow body with a gas inlet, a gas outlet and a condensate drain; a second hollow body with a coolant inlet and a coolant outlet; and a drive unit. The first hollow body encloses the second hollow body at least in part. One of the first hollow body and the second hollow body is pivotally held relative to the other hollow body and includes at least one turbulence-generating body that extends in the direction of the other hollow body. For rotating the pivotally held hollow body the drive unit is couplable to the hollow body. In this manner a single-stage device for cooling and dehumidifying gases that include water vapor is implemented, which device requires little installation space and is of a particularly lightweight construction. Thus the device is particularly well suited for use in vehicles, in particular in aircraft. | 11-27-2014 |
Heiko Oehme, Jena DE
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20120057957 | DEVICE FOR STORING AND PROVIDING OBJECTS HAVING STANDARDIZED DIMENSIONS - A device for loading, storing and providing objects having standardized dimensions includes a storage unit with a carrier plate and four stackers. Each stacker includes a bottom surface disposed on top of the carrier plate. The stackers are configured to store objects stacked perpendicular to the carrier plate. The stackers are disposed symmetrically centered around a rotation axis that is perpendicular to the carrier plate and offset with respect to each other by an angle of 90°. A substructure is disposed underneath the carrier plate. An unloading device is configured to unload a selected object from a first of the stackers that is disposed in a transfer position. The storage unit is rotatable around the rotation axis so as to enable movement of each of the stackers into the transfer position. | 03-08-2012 |
20130068041 | PIPETTING APPARATUS WITH A PIPETTING HEAD COMPRISING A MULTIPLICITY OF PIPETTING CHANNELS DISPOSED IN AN ARRANGEMENT PATTERN - A pipetting apparatus including a pipetting head with a plurality of pipetting channels disposed in an arrangement pattern. Each pipetting channel includes a plunger and a cylinder. The plurality of pipetting channels includes at least two groups of pipetting channels with different diameters including a group of larger pipetting channels and a group of smaller pipetting channels. Each of the at least two groups of pipetting channels is disposed in an arrangement pattern in the pipetting head. Larger pipette tips communicate with the group of larger pipetting channels or smaller pipette tips communicate with the group of smaller pipetting channels. | 03-21-2013 |
Hermann Oehme, Lubeck DE
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20100126102 | Hollow Profiled Element, Particularly for a Lattice Tower; Method for the Production of Such a Hollow Profiled Element; Lattice Tower Comprising at Least Three Corner Posts - A hollow section, in particular for a lattice tower, including a first section part and a second section part, wherein the cross-section of the hollow section is formed such that the first section part includes two legs and the second section part is arranged between the legs of the first section part such that, in order to form a closed hollow cross-section, one of the end edges of the second section part is connected to one of the legs and the other end edge of the second section part is connected to the other leg of the first section part such that a partial segment of the particular leg of the first section part projects beyond the connection site. | 05-27-2010 |
Ina Oehme, Heddesheim DE
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20140329905 | HISTONE DEACETYLASE 10-INHIBITOR CO-TREATMENT IN CANCER - The present invention relates to a method of identifying a subject being susceptible to a co-treatment with an histone deacetylase 10 (HDAC10)-inhibitor, said subject being in need of and/or being treated with cancer therapy against a cancer, comprising the steps of a) determining the amount of an HDAC10 gene product and/or an autophagy-related gene 4D (ATG4D) product in a cancer sample from said subject, b) comparing the amount of said HDAC10 gene product as determined in step a) with a reference amount for said HDAC10 gene product and/or the amount of ATG4D product as determined in step a) with a reference amount for said ATG4D product, and c) identifying a subject being susceptible to co-treatment with an HDAC10-inhibitor. Moreover, The present invention relates to a method of predicting the risk of recurrence and/or progression of a cancer in an subject treated by cancer therapy, comprising the steps of a) determining the amount of an HDAC10 gene product and/or an ATG4D product in a cancer sample from said subject, b) comparing the amount of said HDAC10 gene product as determined in step a) with a reference amount for said HDAC10 gene product and/or the amount of ATG4D product as determined in step a) with a reference amount for said ATG4D product, and c) predicting the risk of recurrence and/or progression of a cancer treated by cancer therapy. The present invention also relates to a device for identifying a subject being susceptible to co-treatment with an HDAC10-inhibitor, a kit adapted to carry out the method of the present invention. Finally, the invention relates to 2-(4-butoxyphenyl)-N-hydroxyacetamide (bufexamac) for use in treating cancer in a subject, wherein said bufexamac is to be applied in a co-treatment with cancer therapy. | 11-06-2014 |
Klaus Oehme, Gaildorf DE
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20100162854 | SCREWDRIVING SYSTEM WITH VARIABLY ADJUSTABLE SCREWDRIVING SPINDLES - The invention relates to a method for screwing in several fastening means such as screws/nuts, which are disposed especially on a circular path, with the aid of a screwing mechanism ( | 07-01-2010 |
Sven Oehme, Ober-Hilbersheim DE
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20090077099 | Method and Infrastructure for Storing Application Data in a Grid Application and Storage System - A grid application and storage system to enhance data access. The grid application and storage system comprises a plurality of grid application storage nodes with at least one storage system, said grid application storage nodes being remote to each other and connected via inter-connections; at least one application process distributed across said grid application storage nodes; and at least one grid node control process also distributed across said grid application storage nodes, said grid node control process managing grid application storage node operations. A plurality of client systems are connected to said grid application and storage system via a network for deploying said application process and accessing application data stored on said grid application storage nodes. | 03-19-2009 |
Sven Oehme, Mainz DE
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20090319532 | METHOD OF AND SYSTEM FOR MANAGING REMOTE STORAGE - A method of managing remote storage sets retention grace period, an archive retention period, and a backup retention period all equal to the same time period. In response to receiving a request to migrate a file to remote storage by any one of HSM, archive, or backup, the method creates a stub of the file, stores the stub in local storage, moves the file to remote storage, and backs up the file at the remote storage. In response to receiving a request to access an HSM file, the method determines if the requested file is in HSM remote storage; if so, the method returns the requested file from remote storage; if not; the method determines if the requested file is in archive remote storage or backup storage and, if so, returns the requested file from said remote storage. In response to receiving a request to access an archived file, the method determines if the requested file is in archive remote storage; if so, the method returns the requested file; if not, the method determines if the requested file is in HSM remote storage or backup remote storage and, if so, returns the requested. In response to receiving a request to access a backup file, the method determines if the requested file is in backup remote storage; if so, the method returns the requested file; if not, the method determining if the requested file is in archive remote storage or HSM remote storage and, if so, returns the requested file. | 12-24-2009 |