Patent application number | Description | Published |
20080261287 | Metabolic Engineering of Xylos Fermentation - The present invention relates to further genetic modifications in eukaryotic host cells that have been transformed to express a xylose isomerase that confers the host cell the ability of isomerising xylose to xylulose. The further genetic modifications are aimed at improving the efficiency of xylose metabolism and include e.g. reduction of unspecific aldose reductase activity, increased xylulose kinase activity and increased flux of the pentose phosphate pathway. The modified host cells of the invention are suitable for the production of a wide variety of fermentation products, including ethanol, in fermentation processes in which a source of xylose or a source of xylose and glucose are used as carbon source. | 10-23-2008 |
20100086965 | METABOLIC ENGINEERING OF ARABINOSE-FERMENTING YEAST CELLS - The invention relates to an eukaryotic cell expressing nucleotide sequences encoding the ara A, ara B and ara D enzymes whereby the expression of these nucleotide sequences confers on the cell the ability to use L-arabinose and/or convert L-arabinose into L-ribulose, and/or xylulose 5-phosphate and/or into a desired fermentation product such as ethanol. Optionally, the eukaryotic cell is also able to convert xylose into ethanol. | 04-08-2010 |
20100248233 | ACETYL-COA PRODUCING ENZYMES IN YEAST - The present invention relates to a method of identifying a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytosol of) a yeast cell comprising: a) providing a mutated yeast cell comprising a deletion of at least one gene of the (PDH) by-pass, selected from the genes encoding the enzymes pyruvate decarboxylase (PDC), acetaldehyde dehydrogenase (ALD), and acetyl-CoA synthetase (ACS); b) transforming said mutated yeast cell with an expression vector comprising a heterologous nucleotide sequence encoding a candidate polypeptide having potential enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA; c) testing said recombinant mutated yeast cell for its ability to grow on minimal medium containing glucose as sole carbon source, and d) identifying said candidate polypeptide as a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytosol of) said yeast cell when growth of said cell is observed. The invention further relates to a method of producing a fermentation production such as butanol. | 09-30-2010 |
20120208231 | METABOLIC ENGINEERING OF ARABINOSE-FERMENTING YEAST CELLS - The invention relates to an eukaryotic cell expressing nucleotide sequences encoding the ara A, ara B and ara D enzymes whereby the expression of these nucleotide sequences confers on the cell the ability to use L-arabinose and/or convert L-arabinose into L-ribulose, and/or xylulose 5-phosphate and/or into a desired fermentation product such as ethanol. Optionally, the eukaryotic cell is also able to convert xylose into ethanol. | 08-16-2012 |
20120225451 | METABOLIC ENGINEERING OF XYLOSE-FERMENTING EUKARYOTIC CELLS - The present invention relates to genetic modifications in eukaryotic host cells that have been transformed to express a xylose isomerase that confers on the host cell the ability to isomerize xylose to xylulose. These genetic modifications are aimed at improving the efficiency of xylose metabolism and include. e.g., reduction of nonspecific aldose reductase activity, increased xylulose kinase activity and increased flux of the pentose phosphate pathway. The modified host cells of the invention are suitable for the production of a wide variety of fermentation products, including ethanol, in fermentation processes in which a source of xylose or a source of xylose and glucose are used as carbon source. | 09-06-2012 |
20140030730 | ACETYL-COA PRODUCING ENZYMES IN YEAST - The present invention relates to a method of identifying a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytosol of) a yeast cell comprising: a) providing a mutated yeast cell comprising a deletion of at least one gene of the (PDH) by-pass, selected from the genes encoding the enzymes pyruvate decarboxylase (PDC), acetaldehyde dehydrogenase (ALD), and acetyl-CoA synthetase (ACS); b) transforming said mutated yeast cell with an expression vector comprising a heterologous nucleotide sequence encoding a candidate polypeptide having potential enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA; c) testing said recombinant mutated yeast cell for its ability to grow on minimal medium containing glucose as sole carbon source, and d) identifying said candidate polypeptide as a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytosol of) said yeast cell when growth of said cell is observed. The invention further relates to a method of producing a fermentation production such as butanol. | 01-30-2014 |
Patent application number | Description | Published |
20090166453 | Process for Yarn or Sliver Refining - The invention discloses a process for refining yarn or sliver having a length of at least 1 meter, comprising the step of feeding the yarn or sliver and a liquid into a refiner, which comprises refiner fillings having a body surrounding a central hole ( | 07-02-2009 |
20110020593 | BALLISTIC RESISTANT ARTICLES COMPRISING ELONGATE BODIES - A ballistic-resistant moulded article comprising a compressed stack of sheets comprising reinforcing elongate bodies and an organic matrix material, the direction of the elongate bodies within the compressed stack being not unidirectionally, wherein the elongate bodies are tapes with a width of at least 2 mm and a thickness to width ratio of at least 10:1 with the stack comprising 0.2-8 wt. % of an organic matrix material. | 01-27-2011 |
20110041677 | BALLISTIC-RESISTANT ARTICLES COMPRISING TAPES - Ballistic-resistant moulded article comprising a compressed stack of sheets comprising tapes of a reinforcing material, characterised in that at least one sheet comprises woven tapes as weft and as warp, at least some of the tapes having a width of at least 10 mm. A method for manufacturing the ballistic-resistant moulded article is also claimed. | 02-24-2011 |
20130280509 | PAPER COMPRISING MICROFILAMENTS - Paper with a grammage of 10-100 g/m | 10-24-2013 |