Patent application number | Description | Published |
20120233668 | Pluggable Allocation in a Cloud Computing System - In one embodiment, a cloud computing system provides user extensibility by providing a plugin interface for major systems. Plugin interfaces for a compute service, object service, network service, authentication and authorization service, message service, and image service are disclosed. One or more of the plugin interfaces can be used to alter the allocation of virtual to physical resources across multiple services. Compound services and smart allocation facilities are possible with user-directed modification. | 09-13-2012 |
20160072727 | Pluggable Allocation in a Cloud Computing System - In one embodiment, a cloud computing system provides user extensibility by providing a plugin interface for major systems. Plugin interfaces for a compute service, object service, network service, authentication and authorization service, message service, and image service are disclosed. One or more of the plugin interfaces can be used to alter the allocation of virtual to physical resources across multiple services. Compound services and smart allocation facilities are possible with user-directed modification. | 03-10-2016 |
Patent application number | Description | Published |
20110003384 | COMPOSITIONS AND METHODS OF USE FOR MGD-CSF IN DISEASE TREATMENT - Disclosed is a newly identified secreted molecule, identified herein as “monocyte, granulocyte, and dendritic cell colony stimulating factor” (MGD-CSF), the polypeptide sequence, and polynucleotides encoding the polypeptide sequence. Also provided is a procedure for producing the polypeptide by recombinant techniques employing, for example, vectors and host cells. Additionally, procedures are described to modify the disclosed novel molecules of the invention to prepare fusion molecules. Also disclosed are methods for using the polypeptides and active fragments thereof for treatment of a variety of diseases, including, for example, cancer, autoimmune and inflammatory diseases, infectious diseases, and recurrent pregnancy loss. | 01-06-2011 |
20120258071 | Compositions and Methods of Use for MGD-CSF in Disease Treatment - Disclosed is a newly identified secreted molecule, identified herein as “monocyte, granulocyte, and dendritic cell colony stimulating factor” (MGD-CSF), the polypeptide sequence, and polynucleotides encoding the polypeptide sequence. Also provided is a procedure for producing the polypeptide by recombinant techniques employing, for example, vectors and host cells. Additionally, procedures are described to modify the disclosed novel molecules of the invention to prepare fusion molecules. Also disclosed are methods for using the polypeptides and active fragments thereof for treatment of a variety of diseases, including, for example, cancer, autoimmune and inflammatory diseases, infectious diseases, and recurrent pregnancy loss. | 10-11-2012 |
Patent application number | Description | Published |
20090080439 | SIMPLE, RELIABLE, CORRECTIONLESS COMMUNICATION MECHANISM - A server interconnect system includes a first server node operable to send and receive messages and a second server nodes operable to send and receive messages. The system further comprises a first interface unit in communication with the first server node and a second interface unit in communication with the second server node. The first interface unit has a first set of message send registers and a first set of message receive registers. Similarly, the second interface unit has a second set of message send registers and a second set of message receive registers. The server interconnect system also includes a communication switch that receives and routes a message from the first or second server nodes when either of the first or second registers indicates that a valid message is ready to be sent. A method implemented by the server interconnect system is also provided. | 03-26-2009 |
20090083392 | SIMPLE, EFFICIENT RDMA MECHANISM - A server interconnect system for sending data includes a first server node and a second server node. Each server node is operable to send and receive data. The interconnect system also includes a first and second interface unit. The first interface unit is in communication with the first server node and has one or more RDMA doorbell registers. Similarly, the second interface unit is in communication with the second server node and has one or more RDMA doorbell registers. The system also includes a communication switch that is operable to receive and route data from the first or second server nodes using a RDMA read and/or an RDMA write when either of the first or second RDMA doorbell registers indicates that data is ready to be sent or received. | 03-26-2009 |
20100180195 | METHOD AND APPARATUS FOR HARDWARE XML ACCELERATION - A method and apparatus for accelerating processing of a structured document. A hardware XML accelerator includes one or more processors (e.g., CMT processors), one or more hardware XML parser units, one or more cryptographic units and various interfaces (e.g., to memory, a network, a communication bus). An XML document may be processed in its entirety or may be parsed in segments (e.g., as it is received). A parser unit parses a document or segment character by character, validates characters, assembles tokens from the document, extracts data, generates token headers (to describe tokens and data) and forwards the token headers and data for consumption by an application. A cryptographic unit may enforce web security, XML security or some other security scheme, by providing encryption/decryption functionality, computing digital signatures, etc. Software processing, bus utilization and latencies (e.g., memory, bus) are greatly reduced, thereby providing significantly improved XML processing and security processing throughput. | 07-15-2010 |
Patent application number | Description | Published |
20100297070 | COMPOSITIONS AND METHODS FOR AMELIORATING CNS INFLAMMATION, PSYCHOSIS, DELIRIUM, PTSD or PTSS - The invention provides compositions and methods for ameliorating, treating, reversing or preventing pathology or inflammation in the central nervous system (CNS), or the brain, caused or mediated by NFkB, IL-6, IL-6-R, NADPH oxidase (Nox), and/or superoxide and/or hydrogen peroxide production by a NADPH oxidase, including for example ameliorating, treating, reversing or preventing schizophrenia, psychosis, delirium, e.g., post-operative delirium, drug-induced psychosis, psychotic features associated with frailty syndrome (FS), aging, depression, dementias; traumatic war neurosis, post traumatic stress disorder (PTSD) or post-traumatic stress syndrome (PTSS), Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig's Disease), and/or Multiple Sclerosis (MS). The invention also provides methods for purifying a C60 fullerene, C3 (tris malonic acid C60) or malonic acid derivatives. | 11-25-2010 |
Patent application number | Description | Published |
20090165730 | PET ENCLOSURE - A collapsible pet enclosure is provided. The enclosure includes a pliable cover supported by a rigid, but foldable, frame. The cover includes an opening in a top panel such that the enclosure is top loading. The cover is completely removable from the frame so that it can be machine washed. The frame is of one-piece jointed construction so that it is collapsible for easy transportation or storage. Because all frame components are jointedly attached to one another, the frame does not include any loose components that are easily lost. The enclosure is quick and easy to set up and collapse. | 07-02-2009 |
20100242855 | PET ENCLOSURE - A pet enclosure includes a cover and a support frame. The cover includes a bottom panel, a top panel opposite the bottom panel, and a plurality of side panels extending between the bottom panel and the top panel to define an interior space of the cover. An aperture is defined in at least one of the top panel and one of the plurality of side panels for accessing the interior space. The support frame is pivotable between a collapsed configuration and an upright configuration and is insertable into the interior space of the cover through the aperture in the collapsed configuration of the support frame. The support frame is also pivotable from the collapsed configuration to the upright configuration while disposed within the interior space of the cover. | 09-30-2010 |
20120103273 | PET ENCLOSURE - A pet enclosure includes a cover and a collapsible support frame. The cover includes a bottom panel, a top panel opposite the bottom panel, and a plurality of side panels extending between the bottom panel and the top panel to define an interior space of the cover, wherein an aperture is defined in the cover for accessing the interior space. The collapsible support frame is configured for insertion into the interior space of the cover via the aperture, and the support frame includes a floor arrangement, a first truss hingedly connected to the floor arrangement, and a second truss hingedly connected to the floor arrangement opposite the first truss. The first truss and the second truss are movable relative to one another within the interior space of the cover between a collapsed configuration of the support frame and an uncollapsed configuration of the support frame. | 05-03-2012 |
20130118415 | PET ENCLOSURE - A pet enclosure includes an expandable cover and a collapsible support frame. The cover comprises a roof, a floor opposite the roof, and sides connecting the roof to the floor, wherein the sides include a first side and a second side opposite the first side. The support frame comprises a first truss adjacent the first side, a second truss adjacent the second side, and a support member extending from the first truss to the second truss. The first truss and the second truss are pivotable relative to the support member toward one another into a collapsed configuration of the support frame and away from one another into an uncollapsed configuration of the support frame. Pivoting the trusses from the collapsed configuration into the uncollapsed configuration rearranges the cover from an unexpanded arrangement into an expanded arrangement. The cover in the expanded arrangement defines an interior compartment for housing a pet. | 05-16-2013 |
Patent application number | Description | Published |
20090004189 | BIOLOGICAL MARKERS PREDICTIVE OF RHEUMATOID ARTHRITIS RESPONSE TO B-CELL ANTAGONISTS - Methods and assays examining expression of one or more biomarkers in a sample are provided for predicting or indicating the effectiveness of treatment of a rheumatoid arthritis patient with a B-cell antagonist. Methods are provided for identifying patients whose rheumatoid arthritis is likely to be responsive to B-cell-antagonist, anti-rheumatoid arthritis therapy. Methods for treating such patients with B-cell antagonists that incorporate the above methodology are also provided. Further provided are kits and articles of manufacture useful for such methods. | 01-01-2009 |
20100092977 | IRF-5 HAPLOTYPES IN SYSTEMIC LUPUS ERYTHEMATOSUS - Methods and materials involved in diagnosing SLE are provided herein. The methods and materials can be used to diagnose SLE and/or assess a mammal's susceptibility to develop SLE, based on the presence or absence of one or more IRF-5 variants. | 04-15-2010 |
20100099101 | METHODS FOR TREATING, DIAGNOSING, AND MONITORING LUPUS - Methods of identifying, diagnosing, and prognosing lupus, including certain subphenotypes of lupus, are provided, as well as methods of treating lupus, including certain subpopulations of patients. Also provided are methods for identifying effective lupus therapeutic agents and predicting responsiveness to lupus therapeutic agents. | 04-22-2010 |
20110027822 | SYSTEMIC LUPUS ERYTHEMATOSUS - This document relates to methods and materials involved in diagnosing SLE. For example, this document relates to methods and materials involved in diagnosing SLE, diagnosing severe SLE, and assessing a mammal's susceptibility to develop severe SLE. For example, this document provides nucleic acid arrays that can be used to diagnose SLE in a mammal. Such arrays can allow clinicians to diagnose SLE based on a simultaneous determination of the expression levels of many genes that are differentially expressed in SLE patients as compared to healthy controls. In addition, methods and materials for assessing SLE activity, determining the likelihood of experiencing active SLE, and detecting SLE treatment effectiveness are provided herein. | 02-03-2011 |
20110046094 | METHODS AND COMPOSITIONS FOR IDENTIFYING AND TREATING LUPUS - A unique set of genetic variations associated with lupus are provided. Also provided are methods for detecting such genetic variations and for assessing risk of developing lupus as well as for diagnosing and treating lupus. | 02-24-2011 |
20120003641 | GENETIC POLYMORPHISMS IN AGE-RELATED MACULAR DEGENERATION - Methods for determining whether a patient is at increased risk of developing wet AMD or whether a patient has an increased likelihood of benefiting from treatment with a high-affinity anti-VEGF antibody. | 01-05-2012 |
20130034544 | METHODS FOR TREATING, DIAGNOSING, AND MONITORING LUPUS - Methods of identifying, diagnosing, and prognosing lupus, including certain subphenotypes of lupus, are provided, as well as methods of treating lupus, including certain subpopulations of patients. The methods provided are based on a set of alleles associated with systemic lupus erythematosus (SLE) risk loci including BLK, TNIP1, PRDM1, JAZF1, UHRF1BP1, IL1 O, IFIH1, CFB, CEC16A, IL12B and SH2B3 that contribute to SLE risk. Also provided are methods for identifying effective lupus therapeutic agents and predicting responsiveness to lupus therapeutic agents. | 02-07-2013 |
20140037618 | METHOD OF TREATING AUTOIMMUNE INFLAMMATORY DISORDERS USING IL-23R LOSS-OF-FUNCTION MUTANTS - The present invention relates to compositions and methods of diagnosing and treating autoimmune and inflammatory disorders that are characterized by IL-23R loss-of-function mutations. | 02-06-2014 |
20140154247 | Biological Markers and Methods for Predicting Response to B-Cell Antagonists - Biological markers that predict patient responsiveness to B-cell antagonists are provided. Also provided are methods of using such biological markers. In addition, methods for identifying patients suffering from an autoimmune disease, e.g., rheumatoid arthritis, who are not likely to respond to B-cell antagonists are provided, as are methods of treating such patients. Methods for selecting therapeutic agents to treat such patients are also provided. | 06-05-2014 |
Patent application number | Description | Published |
20110095007 | THERMAL FLUX PROCESSING BY SCANNING A FOCUSED LINE BEAM - The thermal processing device includes a stage, a continuous wave electromagnetic radiation source, a series of lenses, a translation mechanism, a detection module, a three-dimensional auto-focus, and a computer system. The stage is configured to receive a substrate thereon. The continuous wave electromagnetic radiation source is disposed adjacent the stage, and is configured to emit continuous wave electromagnetic radiation along a path towards the substrate. The series of lenses is disposed between the continuous wave electromagnetic radiation source and the stage, and are configured to condense the continuous wave electromagnetic radiation into a line of continuous wave electromagnetic radiation on a surface of the substrate. The translation mechanism is configured to translate the stage and the line of continuous wave electromagnetic radiation relative to one another. The detection module is positioned within the path, and is configured to detect continuous wave electromagnetic radiation. | 04-28-2011 |
20120205347 | Scanned laser light source - The thermal processing device includes a stage, a continuous wave electromagnetic radiation source, a series of lenses, a translation mechanism, a detection module, a three-dimensional auto-focus, and a computer system. The stage is configured to receive a substrate thereon. The continuous wave electromagnetic radiation source is disposed adjacent the stage, and is configured to emit continuous wave electromagnetic radiation along a path towards the substrate. The series of lenses is disposed between the continuous wave electromagnetic radiation source and the stage, and are configured to condense the continuous wave electromagnetic radiation into a line of continuous wave electromagnetic radiation on a surface of the substrate. The translation mechanism is configured to translate the stage and the line of continuous wave electromagnetic radiation relative to one another. The detection module is positioned within the path, and is configured to detect continuous wave electromagnetic radiation. | 08-16-2012 |
20150053659 | Thermal processing by scanning a laser line beam - The thermal processing device includes a stage, a continuous wave electromagnetic radiation source, a series of lenses, a translation mechanism, a detection module, a three-dimensional auto-focus, and a computer system. The stage is configured to receive a substrate thereon. The continuous wave electromagnetic radiation source is disposed adjacent the stage, and is configured to emit continuous wave electromagnetic radiation along a path towards the substrate. The series of lenses is disposed between the continuous wave electromagnetic radiation source and the stage, and are configured to condense the continuous wave electromagnetic radiation into a line of continuous wave electromagnetic radiation on a surface of the substrate. The translation mechanism is configured to translate the stage and the line of continuous wave electromagnetic radiation relative to one another. The detection module is positioned within the path, and is configured to detect continuous wave electromagnetic radiation. | 02-26-2015 |
Patent application number | Description | Published |
20120040769 | Tennis and golf training device having an adjustable hoop - A portable training device to be used by one practicing the game of tennis or golf. The training device includes a stand to rest on a flat surface, an adjustable hoop through which a tennis ball or a golf ball is hit, and a hoop support extending between the stand and the hoop. The adjustable hoop is rotatable between a vertical position, standing upwardly from and in axial alignment with the hoop support, and a horizontal position, facing the flat surface in perpendicular alignment with the hoop support. The length of the hoop support is adjustable so that the distance between the hoop and the stand can be correspondingly adjusted to meet the needs of the user. | 02-16-2012 |
20130040762 | TENNIS, GOLF AND BASKETBALL TRAINING DEVICE HAVING AN ADJUSTABLE HOOP - A portable training device to be used during sports and non-sports related practice activities. The training device includes a stand to rest on a surface, an adjustable hoop through which an object is moved during practice, and a hoop support extending between the stand and the hoop. In one embodiment, the adjustable hoop is rotatable between a vertical position, standing upwardly from and in axial alignment with the hoop support, and a horizontal position, facing the flat surface in perpendicular alignment with the hoop support. The length of the hoop support is adjustable so that the distance between the hoop and the stand can be correspondingly adjusted to meet the needs of the user. | 02-14-2013 |