Patent application number | Description | Published |
20090033398 | Clock Distribution Network Wiring Structure - A wiring structure for clock signals has two or more parallel clock signal wires disposed in adjacent power wire bays that span the distance between the sinks to which the clock signal wires are to be coupled. The parallel clock signal wires are shorted one to another by stubs placed at locations in order to time the clock wiring structure. The delay tuning of the structure is obtained by the discrete movement of wiring stubs between the wiring bays of the pre-defined power grid. | 02-05-2009 |
20100001696 | SYSTEM TO IMPROVE A MULTISTAGE CHARGE PUMP AND ASSOCIATED METHODS - A system to improve a multistage charge pump may include a capacitor, a first plate carried by the capacitor, and a second plate carried by the capacitor opposite the first plate. The system may also include a clock to control charging and discharging of the capacitor. The system may further include a power supply to provide a power supply voltage across the first plate and the second plate during charging of the capacitor. The system may also include a voltage line to lift the second plate to an intermediate voltage during discharging of the capacitor. The system may further include an output line connected to the first plate during discharging of the capacitor to provide an output voltage. | 01-07-2010 |
20100001709 | SYSTEM TO GENERATE A REFERENCE FOR A CHARGE PUMP AND ASSOCIATED METHODS - A system to generate a reference for a charge pump may include a diode-connected transistor providing a reference voltage, and an output transistor. The system may also include a reference circuit to provide a current that is substantially temperature insensitive and the reference circuit delivers the current across the diode-connected transistor thereby enabling the reference voltage to move with processing of the diode-connected transistor. | 01-07-2010 |
20100002478 | SYSTEM TO IMPROVE A VOLTAGE MULTIPLIER AND ASSOCIATED METHODS - A system to improve a voltage multiplier may include a voltage multiplier circuit, and a capacitor carried by the multiplier circuit. The system may also include a transistor to charge an up voltage of the capacitor. | 01-07-2010 |
20110033017 | Method and Apparatus for Generating Synchronization Signals for Synchronizing Multiple Chips in a System - A clock generator circuit for generating synchronization signals for a multiple chip system. The clock generator circuit comprises generation of a synchronization signal from a reference clock and chip global clock with edge detection logic. In high performance server system design with multiple chips, a common practice for server systems is to use feedback clock and delayed reference clock to generate the synchronization signal. The generated synchronization signal is transferred to latches clocked by the global clock to be used for chip synchronization functions. As the system clock frequency is pushed higher, the phase difference between generated synchronization signal clocked by feedback clock and receiving latch clocked by global clock is becoming such a large portion of cycle time that this signal cannot be transferred deterministically. This invention resolves the uncertainty problem and allows the synchronization signals to be generated deterministically independent of the chip global clock cycle time. | 02-10-2011 |
20110320700 | Concurrent Refresh In Cache Memory - Concurrent refresh in a cache memory includes calculating a refresh time interval at a centralized refresh controller, the centralized refresh controller being common to all cache memory banks of the cache memory, transmitting a starting time of the refresh time interval to a bank controller, the bank controller being local to, and associated with, only one cache memory bank of the cache memory, sampling a continuous refresh status indicative of a number of refreshes necessary to maintain data within the cache memory bank associated with the bank controller, requesting a gap in a processing pipeline of the cache memory to facilitate the number of refreshes necessary, receiving a refresh grant in response to the requesting, and transmitting an encoded refresh command to the bank controller, the encoded refresh command indicating a number of refresh operations granted to the cache memory bank associated with the bank controller. | 12-29-2011 |
Patent application number | Description | Published |
20090027075 | System And Method of Digitally Testing An Analog Driver Circuit - A circuit and method of testing an analog driver circuit using digital scan-based test methodologies. The circuit of the present invention comprises a control circuit for generating signals in response to a test enable signal, a differential driver circuit for receiving a differential input signal, amplifying the differential input signal and transmitting a differential output signal in response to the differential input signal and the signals generated by the control circuit, a programmable termination impedance circuit for generating a differential termination impedance at the output node of the differential driver circuit in response the signals generated by the control circuit, and a differential receiver circuit for receiving the differential output from the differential driver circuit, convert the differential output signal to a single ended signal and transmitting the single ended signal, all in response to the test enable signal. The method of the present invention comprises digitally testing the differential driver circuit by activating a test enable signal, skewing the differential output termination impedance in response to the test enable signal, adjusting a voltage offset of the differential receiver circuit in response to the test enable signal, selecting a power level for the differential driver circuit in response to the test enable signal, enabling a decoder in response to the test enable signal, wherein the decoder activates only one segment of the differential driver circuit during any one test sequence, activating one of the segments for testing, stimulating the differential driver circuit with digital test patterns, receiving an output of the differential driver circuit by the differential receiver circuit, converting the received differential driver output to a single-ended signal, observing the single-ended signal; and deactivating the test enable signal. | 01-29-2009 |
Patent application number | Description | Published |
20110110879 | Compositions and Methods for Enhancing Eyelashes - Cosmetic compositions comprising creatine and low amounts of a biotinylated tripeptide are disclosed, as well as methods of using such compositions to improve the appearance of eyelashes. These compositions are believed to have synergistic modulatory activities in a number of biochemical pathways implicated in lash health. | 05-12-2011 |
20110305781 | Use of Eclipta Prostrata and Other PPAR-GAMMA Inhibitors in Cosmetics and Compositions Thereof - The present invention describes compositions and methods for improving the appearance of skin, particularly, treating, ameliorating, preventing, delaying, and/or improving one or more signs of excess accumulation and/or production of subcutaneous fat, such as cellulite, and conditions related thereto, by topically applying compositions comprising | 12-15-2011 |
20120004302 | Cosmetic Use of N-Substituted Sulfonyloxybenzylamines and Related Compounds - Cosmetic compositions comprising N-substituted sulfonyloxybenzylamines and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The N-substituted sulfonyloxybenzylamines are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging. | 01-05-2012 |
20130224318 | Use of CPT-1 Modulators and Compositions Thereof - The present invention describes methods for improving the appearance of skin, particularly, treating, ameliorating, preventing, delaying, and/or improving one or more signs of excess accumulation and/or production of subcutaneous fat, such as cellulite, and conditions related thereto, by topically applying compositions comprising Carnitine Palmitoyl Transferase-1 (CPT-1) modulators, optionally with other anti-lipid agents; and also describes compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating loss of subcutaneous fat in the skin, wherein the compositions include natural plant constituents that stimulate lipid synthesis. | 08-29-2013 |
20140024603 | Method for Enhancing the Growth and Fullness of Hair - New fibroblast growth factor receptor 1 (FGFR1) inhibitors have been identified which are useful for promoting the retention and/or growth of keratin fibers, such as hair of the scalp, hair of the face (moustache, beard, etc.), eyebrows, eyelashes, and the like. The FGFR1 inhibitors may be formulated in effective amounts in a variety of cosmetic and personal care products. | 01-23-2014 |
20140161910 | Serissa Japonica Extracts and Methods of Use - Methods of using extracts of | 06-12-2014 |
20140161911 | Hoya Carnosa Extracts and Methods of Use - Methods of using extracts of | 06-12-2014 |
20140161918 | Use of Adipose Septa Protein Modulators and Compositions Thereof - Methods of using adipose septa protein modulators to impart anti-aging benefits to the skin and/or improve skin conditions resulting from weakened or compromised adipose septa. | 06-12-2014 |
20140271953 | Use of Melicope Extracts to Improve Conditions Caused by Excess Lipids - Methods of using extracts of | 09-18-2014 |
20140329898 | Cosmetic Use of N-Substituted Sulfonyloxybenzylamines and Related Compounds - Cosmetic compositions comprising N-substituted sulfonyloxybenzylamines and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The N-substituted sulfonyloxybenzylamines are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging. | 11-06-2014 |
20150209268 | Use of Starfruit Extract as a CPT-1 Modulator and Compositions Thereof - The present invention describes methods for improving the appearance of skin, particularly, treating, ameliorating, preventing, delaying, and/or improving one or more signs of excess accumulation and/or production of subcutaneous fat, such as cellulite, and conditions related thereto, by topically applying compositions comprising Carnitine Palmitoyl Transferase-1 (CPT-1) stimulating aqueous extract of the leaf of | 07-30-2015 |
Patent application number | Description | Published |
20160055072 | METHOD, DEVICE, AND PROGRAM STORAGE DEVICE FOR AUTONOMOUS SOFTWARE LIFE CYCLE MANAGEMENT - A method of searching for and installing a software product on a device is provided. One or more capabilities needed by the device to be served by a software product are determined. The one or more capabilities needed by the device are communicated from a software life cycle management agent on the device to a yellow pages agent outside the device, the communicating comprising formulating a request comprising a list of the capabilities encoded in a description language that defines the capabilities semantically. Then locations of one or more software products matching the one or more capabilities needed by the device may be received from the yellow pages agent. One of the one or more software products to install may be selected based on automatically evaluated criteria. Then the selected software product may be downloaded using its received location, and the selected software product may be installed on the device. | 02-25-2016 |
20160055077 | METHOD, DEVICE, AND PROGRAM STORAGE DEVICE FOR AUTONOMOUS SOFTWARE PRODUCT TESTING - A method of testing a software product is performed. The software product is downloaded to a sandbox located on a device, the sandbox constructed so that actions taken by software inside the sandbox do not affect operations of modules on the device located outside of the sandbox. Information about the software product is obtained. Then one or more test libraries are automatically generated, based on the information, each of the test libraries containing one or more executable functions to test the software product. Then the software product is tested in the sandbox using the one or more test libraries and test data, producing test results, wherein the testing includes obtaining information from one or more components of the device outside of the sandbox. Based at least on the test results, it is determined that the software product should be installed fully on the device. | 02-25-2016 |
Patent application number | Description | Published |
20130257871 | Content Customization - A content processing service may analyze an item of original content and identify several objects, attributes of those objects, and relationships between those objects present in the item of original content. The content processing service may also analyze a source graph, such as a social graph or supplemental graph, and identify several objects, attributes of those objects, and relationships between those objects present in the source graph. The content processing service may customize the item of original content by selecting an original object and selecting a source graph object. One or more of the attributes or relationships of the selected original object in the item of original content may be replaced by one or more of the attributes or relationships of the selected source graph object, thereby forming an item of modified content. | 10-03-2013 |
20130262127 | Content Customization - A content processing service may analyze an item of original content and identify several objects, attributes of those objects, and relationships between those objects present in the item of original content. The content processing service may also analyze a source graph, such as a social graph or supplemental graph, and identify several objects, attributes of those objects, and relationships between objects present in the source graph. The content processing service may customize the item of original content by selecting an original object and selecting a source graph object. One or more of the attributes or relationships of the selected original object in the item of original content may be replaced by one or more of the attributes or relationships of the selected source graph object. To customize items of audio content, audio content associated with the source graph object may replace audio content associated with the target graph object. | 10-03-2013 |
20140250219 | SYNCHRONIZING TRANSLATED DIGITAL CONTENT - Aspects of the present disclosure relate to one or more configured computing systems identifying when content includes a base content and a translated content that can be synchronously presented. Once a content match is identified, a device to receive synchronization information can also be identified. The synchronization information can enable one or more devices to synchronously present translated content while consuming a base content. For example, an English language audio book may be output synchronously with a Spanish language eBook. | 09-04-2014 |
20140258462 | CONTENT CUSTOMIZATION - A content customization service is disclosed. A user computing device and/or a content customization server may customize a narration associated with an item of content at the request of a listener or a rights-holder. One or more user interfaces may be provided to facilitate these requests. Some examples of customization include specifying settings for the language, accent, mood, or speaker of the narration. Other examples of customization include specifying settings for the bass, treble, pitch, pace, or contrast of the narration. These settings may be collected as narration settings information. The content customization service may distribute this information over an electronic network. The content customization service may provide recommendations to help users select customizations. | 09-11-2014 |
20140258858 | CONTENT CUSTOMIZATION - A content customization service is disclosed. A user computing device and/or a content customization server may customize a narration associated with an item of content at the request of a listener or a rights-holder. One or more user interfaces may be provided to facilitate these requests. Some examples of customization include specifying settings for the language, accent, mood, or speaker of the narration. Other examples of customization include specifying settings for the bass, treble, pitch, pace, or contrast of the narration. The content customization service may select a computing device to perform the customization. For example, the user computing device may modify the narration by itself, or the user computing device may transmit a request for modified narration to the content customization server, which may then transmit modified narration to the user computing device. | 09-11-2014 |
Patent application number | Description | Published |
20120324324 | SYNCHRONIZING RECORDED AUDIO CONTENT AND COMPANION CONTENT - Aspects of the present disclosure relate to synchronously presenting companion content, such as text content of an electronic book, while recording or presenting narration audio content spoken by a narrator. For example, recorded audio content may be received that corresponds to words of the companion content as spoken by a narrator. The recorded audio content may be received at least substantially in real time as the words are spoken. Content synchronization information for the recorded audio content and the text content may be generated, where the content synchronization information maps portions of the recorded audio content to corresponding portions of the text content. The audio content and the text content may be synchronously presented to a user based at least in part on the content synchronization information. | 12-20-2012 |
20130073675 | MANAGING RELATED DIGITAL CONTENT - Aspects of the present disclosure relate to one or more configured computing systems identifying companion content and supplemental content for a base content. Companion content may include, for example, video adaptations of the base content. Supplemental content may include content referenced or related in subject matter to the base content. Information regarding companion content may be utilized to enable a user to interchangeably or synchronously present either a base content (e.g., an eBook or audio book) with the companion content (e.g., a movie adaptation). Information regarding supplemental content may be utilized to present the supplemental content during consumption of a base content, or to save supplemental content for later viewing. | 03-21-2013 |
20130074133 | MANAGING RELATED DIGITAL CONTENT - Aspects of the present disclosure relate to one or more configured computing systems identifying companion content and supplemental content for a base content. Companion content may include, for example, video adaptations of the base content. Supplemental content may include content referenced or related in subject matter to the base content. Information regarding companion content may be utilized to enable a user to interchangeably or synchronously present either a base content (e.g., an eBook or audio book) with the companion content (e.g., a movie adaptation). Information regarding supplemental content may be utilized to present the supplemental content during consumption of a base content, or to save supplemental content for later viewing. | 03-21-2013 |
20140005814 | PACING CONTENT | 01-02-2014 |
20140118800 | ELECTRONIC READING POSITION MANAGEMENT FOR PRINTED CONTENT - Features are disclosed for facilitating content consumption among various formats or representations of a content item. An electronic device may be used to maintain a current content position when consuming a physical printed representation of a content item, either alone or in conjunction with an electronic representation of the content item. The electronic device may be used to retrieve, from a network-accessible server, a user's last position within the content item. The user may then turn to the location within the physical printed representation that corresponds to the last position within the electronic representation. Highlights, comments and other content interactions may be maintained by the electronic device and stored at the network accessible server. From there, content interaction data may be subsequently obtained by the user when resuming content consumption, either from the same device or a different device. | 05-01-2014 |
20140122564 | MANAGING USE OF A SHARED CONTENT CONSUMPTION DEVICE - Features are disclosed for identifying multiple users contending for use of a shared media device with which to present a content item. Users may be detected by the shared media device or a management component, and each user may have previously begun and stopped consumption at a different point within the content item. When multiple users wish to consume the content, a component or module determines which presentation position to use, or creates a new presentation position for use. In cases in which not all users have begun consuming or wish to consume the same content item, a component or module determines which content item to present. | 05-01-2014 |
20150215382 | AUTOMATED TRANSITION OF CONTENT CONSUMPTION ACROSS DEVICES - Features are disclosed for transferring the presentation or playback of content from device to device. The content may include, but is not limited to, aural, video, and multimedia content. A personal device may be detected playing content. A current play position of the content can be obtained, and playback can be halted. The play position can be transferred to a media device wherein playback is automatically resumed. Additionally, the playing of content may be transferred between two or more media devices, for example in response to the movement of a user. Personal device movements and content operations may be monitored in order to determine improvements to the automatic transfer of content consumption from device to device. | 07-30-2015 |
20150261747 | SELECTING AND CONVEYING SUPPLEMENTAL CONTENT - Base items of content may be conveyed by a user computing device. These base items of content may be enhanced with enhancement content, such as sounds, songs, video clips, animations, images, multimedia content, and the like. Characteristics and enhancement objects may be identified in a portion of the base item of content, and enhancement content may be assigned to that portion automatically by a content enhancement service. In one embodiment, enhancement sounds or songs may be provided and conveyed to enhance an audiobook or electronic book. | 09-17-2015 |
Patent application number | Description | Published |
20140128144 | IN-VEHICLE GAMING SYSTEM FOR PASSENGERS - An in-vehicle gaming system may be played by a driver alone, or simultaneously or individually by a driver and/or one or more other users. The in-vehicle gaming system may be activated or controlled by, for example, touch, voice, or gesture. Gameplay is dynamically adjusted based at least in part on environmental factors such that the driver is not distracted from driving the vehicle. Game content is generated based at least in part on environmental factors and user data. | 05-08-2014 |
20140128145 | IN-VEHICLE GAMING SYSTEM FOR A DRIVER - An in-vehicle gaming system may be played by a driver alone, or simultaneously or individually by a driver and/or one or more other users. The in-vehicle gaming system may be activated or controlled by, for example, touch, voice, or gesture. Gameplay is dynamically adjusted based at least in part on environmental factors such that the driver is not distracted from driving the vehicle. Game content is generated based at least in part on environmental factors and user data. | 05-08-2014 |
20140128146 | CUSTOMIZABLE IN-VEHICLE GAMING SYSTEM - An in-vehicle gaming system may be played by a driver alone, or simultaneously or individually by a driver and/or one or more other users. The in-vehicle gaming system may be activated or controlled by, for example, touch, voice, or gesture. Gameplay is dynamically adjusted based at least in part on environmental factors such that the driver is not distracted from driving the vehicle. Game content is generated based at least in part on environmental factors and user data. | 05-08-2014 |
20140256426 | IN-VEHICLE GAMING SYSTEM - An in-vehicle gaming system may be played by a driver alone, or simultaneously or individually by a driver and/or one or more other users. The in-vehicle gaming system may be activated or controlled by, for example, touch, voice, or gesture. Gameplay is dynamically adjusted based at least in part on environmental factors such that the driver is not distracted from driving the vehicle. Game content is generated based at least in part on environmental factors and user data. | 09-11-2014 |
20140377721 | SYNCHRONOUS PRESENTATION OF CONTENT WITH A BRAILLE TRANSLATION - A computing device may provide an interface that enables a user to synchronously present an item of primary content and a corresponding braille translation. The item of primary content may be an audio book, an e-book, or other form of media. The item of primary content may include supplemental information which may correspond, for example, to character descriptions, place descriptions, image descriptions, endnotes, footnotes, glossaries, appendices, commentary from an author, editor, or other party, or to additional supplemental information, and which may also have a corresponding braille translation. During presentation of the item of primary content, a user may indicate that an item of supplemental information associated with a current presentation position of the item of primary content should be presented. In some embodiments, this indication may be in response to an indication to the user that supplemental information is available. The device may then present the supplemental information associated with the current presentation position. | 12-25-2014 |
20140377722 | SYNCHRONOUS PRESENTATION OF CONTENT WITH A BRAILLE TRANSLATION - A computing device may provide an interface that enables a user to synchronously present an item of primary content and a corresponding braille translation. The item of primary content may be an audio book, an e-book, or other form of media. The item of primary content may include supplemental information which may correspond, for example, to character descriptions, place descriptions, image descriptions, endnotes, footnotes, glossaries, appendices, commentary from an author, editor, or other party, or to additional supplemental information, and which may also have a corresponding braille translation. During presentation of the item of primary content, a user may indicate that an item of supplemental information associated with a current presentation position of the item of primary content should be presented. In some embodiments, this indication may be in response to an indication to the user that supplemental information is available. The device may then present the supplemental information associated with the current presentation position. | 12-25-2014 |
20150220479 | ELECTRONIC READING POSITION MANAGEMENT FOR PRINTED CONTENT - Features are disclosed for facilitating content consumption among various formats or representations of a content item. An electronic device may be used to maintain a current content position when consuming a physical printed representation of a content item, either alone or in conjunction with an electronic representation of the content item. The electronic device may be used to retrieve, from a network-accessible server, a user's last position within the content item. The user may then turn to the location within the physical printed representation that corresponds to the last position within the electronic representation. Highlights, comments and other content interactions may be maintained by the electronic device and stored at the network accessible server. From there, content interaction data may be subsequently obtained by the user when resuming content consumption, either from the same device or a different device. | 08-06-2015 |
20150264131 | USER LOCATION-BASED MANAGEMENT OF CONTENT PRESENTATION - Features are disclosed for managing presentation of content to improve the content consumption experience as a user moves around or when there are multiple users. Based on user positions within a content consumption location and optionally on the layout of the location, presentation of content can be adjusted. The volume of audio content may be raised or lowered based on a user's position. Audio or visual content can be paused or stopped if a user leaves the location or the user's view is obstructed. When multiple users are consuming a content item, one or more users may have priority and any adjustment may be made to first improve the experience of the priority user. In some cases, no user has priority, and adjustments may be made to improve the experience of many or all users. | 09-17-2015 |
Patent application number | Description | Published |
20090162878 | METHODS AND COMPOSITIONS FOR DETECTING AND QUANTIFYING SAPPB - The present invention provides methods (assays) for detecting and/or quantifying sAPPβ, a secreted β-secretase (BACE1) cleavage fragment of the β-amyloid precursor protein (APP), in a biological sample. One such method includes contacting a biological sample with a first antibody that selectively binds to a BACE1 cleavage site on sAPPβ and detecting the presence of the antibody. Also provided are compositions, including antibodies that selectively bind to the BACE1 cleavage site of sAPPβ. Kits containing such compositions are also provided. Methods of diagnosing a neurodegenerative disease, such as AD, using the methods and compositions of the present invention are further provided. Methods for identifying BACE1 modulators, candidate compounds that are BACE1 modulators, and methods for treating, preventing or ameliorating neurodegenerative disease, such as AD, using such compounds or pharmaceutical compositions containing such compounds are also provided. | 06-25-2009 |
20100221760 | METHODS AND COMPOSITIONS FOR DETECTING AND QUANTIFYING sAPPbeta - The present invention provides methods (assays) for detecting and/or quantifying sAPPβ, a secreted β-secretase (BACE1) cleavage fragment of the β-amyloid precursor protein (APP), in a biological sample. One such method includes contacting a biological sample with a first antibody that selectively binds to a BACE1 cleavage site on sAPPβ and detecting the presence of the antibody. Also provided are compositions, including antibodies that selectively bind to the BACE1 cleavage site of sAPPβ. Kits containing such compositions are also provided. Methods of diagnosing a neurodegenerative disease, such as AD, using the methods and compositions of the present invention are further provided. Methods for identifying BACE1 modulators, candidate compounds that are BACE1 modulators, and methods for treating, preventing or ameliorating neurodegenerative disease, such as AD, using such compounds or pharmaceutical compositions containing such compounds are also provided. | 09-02-2010 |
20110071124 | Compounds that Inhibit Production of sAPPB and AB and Uses Thereof - The present invention relates to compounds with activity as inhibitors of sAPPβ and Aβ production, and methods for treating, preventing, or ameliorating neurodegenerative diseases, such as Alzheimer's disease and pharmaceutical compositions containing such candidate compounds. | 03-24-2011 |
20120064099 | COMPOUNDS THAT INHIBIT NFKB AND BACE1 ACTIVITY - The present invention relates to compounds with activity as BACE1 and NFκB modulators, and methods for treating, preventing, or ameliorating neurodegenerative diseases, such as Alzheimer's disease. The present invention is also directed to the treatment of diseases related to dysfunction of cell proliferation, the immune system and/or inflammation using such compounds or pharmaceutical compositions containing such candidate compounds. | 03-15-2012 |
20120214186 | METHODS AND COMPOSITIONS FOR DETECTING AND QUANTIFYING sAPPbeta - The present invention provides methods (assays) for detecting and/or quantifying sAPPβ, a secreted β-secretase (BACE1) cleavage fragment of the β-amyloid precursor protein (APP), in a biological sample. One such method includes contacting a biological sample with a first antibody that selectively binds to a BACE1 cleavage site on sAPPβ and detecting the presence of the antibody. Also provided are compositions, including antibodies that selectively bind to the BACE1 cleavage site of sAPPβ. Kits containing such compositions are also provided. Methods of diagnosing a neurodegenerative disease, such as AD, using the methods and compositions of the present invention are further provided. Methods for identifying BACE1 modulators, candidate compounds that are BACE1 modulators, and methods for treating, preventing or ameliorating neurodegenerative disease, such as AD, using such compounds or pharmaceutical compositions containing such compounds are also provided. | 08-23-2012 |
20140275165 | COMPOUNDS THAT INHIBIT NFkB AND BACE1 ACTIVITY - The present invention relates to compounds with activity as BACE1 and NFκB modulators, and methods for treating, preventing, or ameliorating neurodegenerative diseases, such as Alzheimer's disease. The present invention is also directed to the treatment of diseases related to dysfunction of cell proliferation, the immune system and/or inflammation using such compounds or pharmaceutical compositions containing such candidate compounds. | 09-18-2014 |
Patent application number | Description | Published |
20100029817 | Sulfur-containing silane, filled elastomeric compositions containing same and articles made therefrom - Sulfur-containing silane and its partially to substantially complete hydrolyzate(s) are useful as additives for filled elastomeric compositions for tires and other cured rubber articles. | 02-04-2010 |
20110021692 | Sulfur-Containing Silane, Filled Elastomeric Compositions Containing Same And Articles Made Therefrom - Sulfur-containing silanes described herein can serve as coupling agents for fillers in elastomer compositions used, for example, in tires, belts, hoses, shoe soles, seals, gaskets, and the like. The sulfur containing silanes advantageously reduce or eliminate the generation of volatile organic compounds (VOCs) during use. | 01-27-2011 |
20130158159 | EPOXY-CONTAINING POLYSILOXANE OLIGOMER COMPOSITIONS, PROCESS FOR MAKING SAME AND USES THEREOF - The present invention relates to stable, zero or low VOC epoxy-containing polysiloxane oligomer compositions that provide for a high degree of chemical resistance to compositions containing organic resins, while at the same time, maintaining or improving the flexibility of these organic resin-containing compositions, to processes for preparing epoxy-containing polysiloxane oligomer compositions, and to uses in coatings, sealants, adhesives, and composites containing the same. | 06-20-2013 |
20140221531 | EPOXY-CONTAINING POLYSILOXANE OLIGOMER COMPOSITIONS, PROCESS FOR MAKING SAME AND USES THEREOF - The present invention relates to stable, zero or low VOC epoxy-containing polysiloxane oligomer compositions that provide for a high degree of chemical resistance to compositions containing organic resins, while at the same time, maintaining or improving the flexibility of these organic resin-containing compositions, to processes for preparing epoxy-containing polysiloxane oligomer compositions, and to uses in coatings, sealants, adhesives, and composites containing the same. | 08-07-2014 |
20140342164 | COATING COMPOSITION AND METHOD FOR DETERMINING THE UNIFORMITY AND THICKNESS OF A NO-RINSE SILANE PRETREATMENT - The invention is directed to a detectable and stable composition comprising an organofunctional silane and/or hydrolyzate and/or partial or complete condensate thereof, a colloidal metal oxide, a water soluble organic dye having a positive charge and a counterion derived from a carboxylic acid of from 1 to 6 carbon atoms, and water. The invention is also directed to a method for determining the uniformity and film thickness of a detectable composition applied to a substrate comprising applying to the surface of the substrate the detectable composition and measuring an optical property of the applied coating, the resulting measurement being related to the uniformity of the applied composition. | 11-20-2014 |
20150377608 | METHOD FOR DETERMINING THE WEIGHT AND THICKNESS OF A PASSIVATION ORCONVERSION COATING ON A SUBSTRATE - The present invention relates to a method for measuring the weight of a passivation coating composition on a moving substrate with minimal interruption. The method of present invention is especially useful for effective quality control in an industrial setting. | 12-31-2015 |
Patent application number | Description | Published |
20130020466 | Conversion Gain Modulation Using Charge Sharing Pixel - An image sensor including an array of pixel elements is operated according to two operation modes to modulate the conversion gain of the pixel to operate the image sensor based on the impinging light conditions. More specifically, an image sensor pixel element is operated in a high conversion gain mode for low light conditions and in a low conversion gain mode for bright light conditions. The low conversion gain mode implements charge sharing between the floating diffusion and the photodiode. The low conversion gain mode further implements partial reset where the photodiode and the floating diffusion are reset to the same potential and to a potential slightly less than the pinning voltage of the photodiode. | 01-24-2013 |
20140368680 | CONVERSION GAIN MODULATION USING CHARGE SHARING PIXEL - An image sensor including an array of pixel elements is operated according to two operation modes to modulate the conversion gain of the pixel to operate the image sensor based on the impinging light conditions. More specifically, an image sensor pixel element is operated in a high conversion gain mode for low light conditions and in a low conversion gain mode for bright light conditions. The low conversion gain mode implements charge sharing between the floating diffusion and the photodiode. The low conversion gain mode further implements partial reset where the photodiode and the floating diffusion are reset to the same potential and to a potential slightly less than the pinning voltage of the photodiode. | 12-18-2014 |
20150311240 | DEEP WELL PHOTODIODE FOR NIR IMAGE SENSOR - An active pixel image sensor includes a photodiode structure which enables high near-infrared modulation transfer function and high quantum efficiency, with low pinning voltage for a medium- to large-size pixel. The photodiode includes a shallow photodiode region and a deep photodiode region both of a first dopant type, where the length of the shallow photodiode region is larger than the length of the deep photodiode region; and a shallow depleting region and a deep depleting region both of a second dopant type. The deep depleting region surrounds the deep photodiode region on at least two opposite sides. | 10-29-2015 |
20150319386 | IMAGE SENSOR WITH FLOATING DIFFUSION INTERCONNECT CAPACITOR - An image sensor includes a pixel circuit that includes a light sensing element and a charge storage node formed in a substrate, an output element having a control electrode formed in an electrode layer above the substrate, the output element generating an output signal corresponding to charge generated by the light sensing element and held by the charge storage node, and a local metal interconnect that electrically connects the charge storage node to the control electrode. Control wirings that control operations of the pixel circuit are formed in wiring layers that are located above the electrode layer. The metal interconnect is formed in a layer that is located above the electrode layer and below a lowest one of the wiring layers such that a given one of the control wirings overlaps the metal interconnect so as to form a parallel plate capacitor in a region of overlap. | 11-05-2015 |
Patent application number | Description | Published |
20140065828 | SELECTIVE FIN CUT PROCESS - A process is provided for selective removal of one or more unwanted fins during FINFET device fabrication. In one aspect, the process includes: providing a conformal protective layer over multiple fin structures on a substrate; patterning one or more openings over the unwanted fin structure(s); and removing at least a top portion of the unwanted fin structure(s) exposed through the opening(s), the removing including removing at least a portion of the conformal protective layer over the unwanted fin structure(s) exposed through the opening(s). In enhanced aspects, the removing includes removing a hard mask from the at least one unwanted fin structure(s) exposed through the opening(s), and selectively removing semiconductor material of at least one unwanted fin structure(s). The conformal protective layer protects one or more remaining fin structures during the selective removal of the semiconductor material of the unwanted fin structure(s). | 03-06-2014 |
20140179093 | GATE STRUCTURE FORMATION PROCESSES - Gate structures and methods of fabricating gate structures of semiconductor devices are provided. One method includes, for instance: providing a sacrificial layer over a substrate; patterning the sacrificial layer to form a gate opening within the sacrificial layer; providing a gate structure within the gate opening in the sacrificial layer; and removing the sacrificial layer, leaving the gate structure over the substrate. In enhanced aspects, the method includes: forming a reverse sidewall-spacer within the gate opening within the sacrificial layer, and after providing the gate structure, recessing the gate structure within the gate opening, and providing a gate cap within the gate recess in the gate structure. | 06-26-2014 |
20140199845 | SELECTIVE REMOVAL OF GATE STRUCTURE SIDEWALL(S) TO FACILITATE SIDEWALL SPACER PROTECTION - Methods are provided for facilitating fabricating a semiconductor device by selectively etching a gate structure sidewall(s) to facilitate subsequent sidewall spacer isolation. The method includes, for instance: providing a gate structure with a protective layer(s) over the gate structure, the gate structure including one or more sidewalls; selectively removing a portion of the gate structure along at least one sidewall to partially undercut the protective layer(s); and forming a sidewall spacer(s) over the sidewall(s) of the gate structure, with a portion of the sidewall spacer at least partially filling the partial undercut of the protective layer(s), and residing below the protective layer(s). In certain embodiments, the selectively removing includes implanting the sidewall(s) with a dopant to produce a doped region(s) of the gate structure, and subsequently, at least partially removing the doped region(s) of the gate structure selective to an undoped region of the gate structure. | 07-17-2014 |
20140373609 | OPTICAL MONITORING SYSTEM FOR A GAS TURBINE ENGINE - A system for optically monitoring a gas turbine engine includes an optical multiplexer configured to receive multiple images from respective viewports into the gas turbine engine. The optical multiplexer includes a movable reflective device configured to selectively direct at least a portion of each image toward a detector array, and the detector array is directed toward a fixed location on the optical multiplexer. | 12-25-2014 |
20140376588 | SYSTEM AND METHOD FOR ON-LINE OPTICAL MONITORING AND CONTROL OF A GAS TURBINE ENGINE - A system for on-line optical monitoring of a gas turbine engine includes a viewport into a combustor of the gas turbine engine and an optical filter optically coupled to the viewport. The optical filter is configured to receive broad wavelength band thermal radiation from an interior surface of the combustor while the gas turbine engine is in operation, to substantially block wavelengths of the broad wavelength band thermal radiation emitted and/or absorbed by a flame and/or by exhaust gas within the combustor, and to output narrow wavelength band thermal radiation from the interior surface of the combustor. The system also includes a detector array in optical communication with the optical filter. The detector array is configured to receive the narrow wavelength band thermal radiation and to output signals indicative of a two-dimensional intensity map of the narrow wavelength band thermal radiation. | 12-25-2014 |
20140376589 | OPTICAL MONITORING SYSTEM FOR A GAS TURBINE ENGINE - A system for optically monitoring a gas turbine engine includes a viewport into the gas turbine engine, and an optical connection having a first axial end and a second axial end. The first axial end is optically coupled to the viewport and configured to receive an image from the viewport, the optical connection includes a substrate having multiple hollow passages each extending from the first axial end to the second axial end, and each hollow passage includes a reflective coating disposed on an inner surface of the hollow passage to facilitate transmission of a respective portion of the image from the first axial end to the second axial end. In addition, the system includes a detector array in optical communication with the second axial end of the optical connection. The detector array includes multiple detection elements configured to receive multiple respective portions of the image from the hollow passages. | 12-25-2014 |
20140376590 | OPTICAL MONITORING SYSTEM FOR A GAS TURBINE ENGINE - A system for optically monitoring a gas turbine engine includes a viewport having an opening disposed within a casing of the gas turbine engine. The opening extends from an interior side of the casing to an exterior side of the casing, and the viewport is configured to receive an image from inside the casing. The system also includes an optical connection positioned outside the casing and optically coupled to the viewport. The optical connection is configured to convey the image from the viewport to a detector array, and the optical connection includes multiple optical fibers fused to one another to form a unitary substantially rigid fiber bundle. | 12-25-2014 |