Patent application number | Description | Published |
20140147860 | Acoustic Cytometry Methods and Protocols - Various embodiments disclosed herein comprise acoustic cytometry based methods, kits, computer software methods and systems to analyze a variety of bioparticles. In one embodiment, a method for analyzing bioparticles comprises: acoustically focusing one or more bioparticles through an interrogation zone; optically exciting the one or more bioparticles in the interrogation zone with an excitation source; detecting an optical signal from the bioparticles; and analyzing the optical signal to characterize at least one quality or quantity parameter of the bioparticles. Properties of biomolecules that may be analyzed include but are not limited to cell proliferation analysis, live/dead cell discrimination, cell cycle analysis, basic phenotyping, immunophenotyping, rare-event detection, apoptosis, phagocytosis, pinocytosis, detection of phosphoproteins, detection of one or more cellular markers, detection of one or more intracellular marker, detection of cancer cells, detection of pathological markers on a cell, microbial cell analysis and/or picophytoplankton analysis. | 05-29-2014 |
Patent application number | Description | Published |
20080245028 | Thermoforming, with applied pressure and dimensional re-shaping, layered, composite-material structural panel - A method utilizing elevated temperature and applied pressure to form a layered, composite-material structural panel including (a) establishing a layer-stack assembly in the form of a pre-consolidation expanse having everywhere an independent, location-specific, pre-consolidation local thickness T, and including at least a pair of confronting, thermoformable polypropylene-based layers, (b) heating the assembly to a thermoform temperature, (c) compressing the heated assembly to create a thermal bond between the two layers, and to consolidate the assembly into a post-consolidation expanse having everywhere an independent, location-specific, post-consolidation, local thickness t which is less than the respective, associated, pre-consolidation local thickness T, and (d) cooling the consolidated assembly to a sub-thermoform temperature to stabilize it in its consolidated condition. | 10-09-2008 |
20090208724 | Embedded-object, composite-material product - An embedded-object composite product including a solid-state mass of PET, an object embedded in the PET material mass, and a zone possessing a continuous material-density gradient in the PET material mass, with more-dense PET material residing closely adjacent the embedded object, and less-dense PET material residing more distant from that object. This product is produced effectively by non-destructively heating the PET mass from its solid state to allow it to flow as a liquid, by then pressing the object into the heated PET mass to perform object embedment and to create a declining PET-material density in the region adjacent, and progressing from adjacent, the embedded object, and by thereafter cooling the mass to re-solidify it. | 08-20-2009 |
20090308007 | Composite layered panel and methodology including selected regional elevated densification - A heat-formation method for creating a composite, layered structural panel which possesses at least one selected area of elevated densification and reinforcement including (a) providing a pre-heat-formed, layered expanse of compressible, heat-formable, composite sheet material having a reception face and a starter thickness T | 12-17-2009 |
20090308521 | Compression-selective sheet-material density and thickness and methodology - A heat and pressure method for creating, from plural, unconsolidated, composite, heat-and-pressure-formable, compressible starter materials having an initial, combined-material starter density D | 12-17-2009 |
20100151216 | Stratified panel structure possessing interleaved, thin-high-density, thick-low-density core-structure stack arrangement - A generally planar composite panel structure including (a) a stratified, generally planar main body core having perimetral edges, and spaced, generally planar, outwardly facing facial expanses extending substantially to such edges, and (b) in a stacked arrangement within the core, intermediate the mentioned facial expanses, at least one high-density, generally planar, fibre-reinforced layer structure bracketed by a pair of low-density, generally planar layer structures, each of which layer structures extends substantially to the core's perimetral edges. | 06-17-2010 |
20100252195 | Methodology for creating layered panel structure including self-bonded thermoformable and non-thermoformable layer materials - A method of forming a layered, generally planar panel structure including the steps of (a) utilizing applied heat and pressure, causing a melt of resin present in a thermoformable material layer to flow toward and into an adjacent non-thermoformable material layer, and (b) by such utilizing and causing, forming a thermal-compression, mechanical, inter-material-transition bond between the layers. | 10-07-2010 |
20100255283 | Layered panel structure including self-bonded layers of thermoformable and non-thermoformable materials - A layered panel structure including first and second layers formed, respectively, of (a) non-thermoformable, and (b) thermoformable, fibre-strand-reinforced resin, materials, having therebetween a bonding interface formed by resin drawn from the second layer. | 10-07-2010 |
Patent application number | Description | Published |
20090162734 | MANUFACTURING OF FUEL CELL MEMBRANE ELECTRODE ASSEMBLIES INCORPORATING PHOTOCURABLE CATIONIC CROSSLINKABLE RESIN GASKET - A first transport system moves a web comprising a subgasketed CCM layer and an application system applies a crosslinkable resin to at least a subgasketed portion of the subgasketed CCM layer. The crosslinkable resin preferably comprises a photocurable cationic crosslinkable resin. A first curing apparatus subjects an exposed surface of the crosslinkable resin to a photo curing process to initiate curing of the crosslinkable resin. A second transport system moves a GDL into adhering contact with a partially cured exposed surface of the crosslinkable resin of the CCM layer so as to form an MEA layer. A second curing apparatus subjects the GDL, partially cured crosslinkable resin, and CCM layer structure to a thermal curing process to substantially complete curing of the crosslinkable resin. A converting system is configured to receive the MEA layer and produce a plurality of discrete MEAs from the MEA layer. | 06-25-2009 |
20090169949 | ELECTRODE INKS CONTAINING COALESCING SOLVENTS - A catalyst ink is provided comprising: a) solids, comprising: i) a catalyst material, and ii) a polymer electrolyte; b) an aqueous solvent; and c) a coalescing solvent. In some embodiments, the coalescing solvent is selected from the group consisting of alkanes, alkenes, amines, ethers, and aromatic compounds which may optionally be substituted. In some embodiments, the coalescing solvent is selected from the group consisting of partially fluorinated alkanes, partially fluorinated tertiary amines, fully fluorinated alkanes and fully fluorinated tertiary amines. In another aspect, the present disclosure provides a fuel cell membrane electrode assembly comprising a catalyst layer comprising a coalescing solvent. In another aspect, the present disclosure provides a method of making a fuel cell membrane electrode assembly comprising a step of applying a catalyst ink according to the present disclosure to one or more of: a) a polymer electrolyte membrane, and b) a porous, electrically conductive gas diffusion layer. | 07-02-2009 |
20130216932 | Manufacturing of Fuel Cell Membrane Electrode Assemblies Incorporating Photocurable Cationic Crosslinkable Resin Gasket - A first transport system moves a web comprising a subgasketed CCM layer and an application system applies a crosslinkable resin to at least a subgasketed portion of the subgasketed CCM layer. The crosslinkable resin preferably comprises a photocurable cationic crosslinkable resin. A first curing apparatus subjects an exposed surface of the crosslinkable resin to a photo curing process to initiate curing of the crosslinkable resin. A second transport system moves a GDL into adhering contact with a partially cured exposed surface of the crosslinkable resin of the CCM layer so as to form an MEA layer. A second curing apparatus subjects the GDL, partially cured crosslinkable resin, and CCM layer structure to a thermal curing process to substantially complete curing of the crosslinkable resin. A converting system is configured to receive the MEA layer and produce a plurality of discrete MEAs from the MEA layer. | 08-22-2013 |
Patent application number | Description | Published |
20140329281 | Recombinant Production of Steviol Glycosides - Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements. | 11-06-2014 |
20150342234 | Steviol Glycoside Compositions Sensory Properties - Materials and methods for producing particular steviol glycosides, and high-purity compositions of particular steviol glycosides with improved sensory profilesare provided herein. The steviol glycosides can be, for example, rebaudioside D, rebaudioside A, and rebaudioside B, and can be produced by recombinant microorganisms. | 12-03-2015 |
Patent application number | Description | Published |
20080274518 | Polypeptides and Biosynthetic Pathways for the Production of Monatin and its Precursors - Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions. | 11-06-2008 |
20090117625 | Polypeptides and Biosynthetic Pathways for the Production of Monatin and Its Precursors - Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions. | 05-07-2009 |
20110020882 | AMINOTRANSFERASE AND OXIDOREDUCTASE NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USING - The invention provides for aminotransferase and oxidoreductase polypeptides and nucleic acids encoding such polypeptides. Also provided are methods of using such aminotransferase and oxidoreductase nucleic acids and polypeptides. | 01-27-2011 |
20110045547 | ISOMERASES AND EPIMERASES AND METHODS OF USING - The invention provides for isomerase (e.g., racemase) and epimerase polypeptides and nucleic acids encoding such polypeptides. Also provided are methods of using such isomerase (e.g., racemase) and epimerase nucleic acids and polypeptides. | 02-24-2011 |
20130171328 | PRODUCTION OF STEVIOL GLYCOSIDES IN MICROORGANISMS - Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express novel recombinant genes encoding steviol biosynthetic enzymes and UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol or steviol glycosides, e.g., rubusoside or Rebaudioside A, which can be used as natural sweeteners in food products and dietary supplements. | 07-04-2013 |
20130203129 | POLYPEPTIDES AND BIOSYNTHETIC PATHWAYS FOR THE PRODUCTION OF MONATIN AND ITS PRECURSORS - Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions. | 08-08-2013 |
20130273616 | POLYPEPTIDES AND BIOSYNTHETIC PATHWAYS FOR THE PRODUCTION OF MONATIN AND ITS PRECURSORS - Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions. | 10-17-2013 |
20150111260 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - This invention relates to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In some embodiments, the invention is directed to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides in accordance with the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts. In some embodiments, the invention provides polypeptides and biosynthetic pathways that are useful in the production of R-2-hydroxy 2-(indol-3ylmethyl)-4-keto glutaric acid (R-MP) and certain stereoisomers of monatin, such as R,R and S,R monatin, and salts thereof, as well as certain stereoisomers of monatin derivatives, such as the R,R and S,R configurations, and salts thereof. | 04-23-2015 |
Patent application number | Description | Published |
20090068408 | Textured Window Film - A textured window film has a prismatic effect that allows a substantial amount of incoming light to pass through a window while refracting the light at random or semi-random angles in a manner that distorts viewed images. The result is a window film that is brighter and more vibrant while also providing visual privacy. The textured window film can therefore better simulate real textured and colored glass. | 03-12-2009 |
20150140270 | DECORATIVE COVERINGS - A decorative fabricated covering includes a first piece of vinyl. A first ink layer is printed on the first piece of vinyl and a textured layer is printed on top of the first ink layer. A second ink layer is printed on a second separate piece of vinyl. The first and second pieces of vinyl are then laminated together. An overprint layer may be printed on top of the textured layer and a second textured layer may be printed on top of the overprint resin layer. A domed layer may be formed on top of the second ink layer and a reflective material, such as glitter, may be mixed in the second textured layer. | 05-21-2015 |
20150160385 | BIRD ANTI-COLLISION WINDOW FILM - A bird anti-collision film prevents birds from flying into windows by disrupting visible habitat reflections that might appear on the outside of the windows. Instead of simply blocking or absorbing light, the anti-collision film actively refracts and scatters light generating an active light disturbance. The refracted light includes an ultraviolet light range visible by many birds. A textured surface and an optical brightener increase the intensity of the refracted light disturbance. The anti-collision film increases active light disturbance intensity when attached to the inside of a window providing the unique advantages of easy inside window installation and insulation from external weather conditions. | 06-11-2015 |
20160041319 | BIRD ANTI-COLLISION WINDOW FILM - A bird anti-collision film prevents birds from flying into windows by disrupting visible habitat reflections that might appear on the outside of the windows. The anti-collision film blocks and/or absorbs light that may normally be reflected by a window and also actively scatters, and fluoresces light creating an active light disturbance. The disrupted light includes a light range highly visible by many birds but only partially visible by humans. A textured surface in combination with a fluorescent dye in the anti-collision film increases the intensity and range of the light disturbance. The anti-collision film may be attached to the inside of a window providing the unique advantages of easy inside window installation and insulation from external weather conditions. | 02-11-2016 |