Patent application number | Description | Published |
20090117113 | Immunogenic And Therapeutic Compositions For Streptococcus Pyogenes - Group A streptococcal (GAS) antigens useful for providing immunity against | 05-07-2009 |
20090162392 | MUTANT FORMS OF STREPTOLYSIN O - Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against | 06-25-2009 |
20090317420 | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae - The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B | 12-24-2009 |
20100015168 | IMMUNOGENIC COMPOSITIONS FOR STREPTOCOCCUS AGALACTIAE - The invention relates to immunogenic polypeptides derived from epitopes in a Streptococcus agalactiae (“GBS”) protein GBS 80 and their use as prophylactic, diagnostic and therapeutic compositions. The invention also provides nucleic acids encoding the immunogenic polypeptides. Also provided are vectors useful for making such immunogenic polypeptides and host cells transformed with such vectors. In particular, the invention relates to a group immunogenic polypeptides derived from GBS 80. The compositions may include one or more of the immunogenic polypeptides either alone or with other antigenic components. For example, the immunogenic polypeptides may be combined with other GBS antigens to provide therapeutic compositions with broader range. In addition, the immunogenic polypeptides may also include flanking portions of the GBS 80 protein. | 01-21-2010 |
20100015212 | IMMUNOGENIC BACTERIAL VESICLES WITH OUTER MEMBRANE PROTEINS - Knockout of the meningococcal mltA homolog gives bacteria that spontaneously release vesicles that are rich in immunogenic outer membrane proteins and that can elicit cross-protective antibody responses with higher bactericidal titres than OMVs prepared by normal production processes. Thus the invention provides a bacterium having a knockout mutation of its mltA gene. The invention also provides a bacterium, wherein the bacterium: (i) has a cell wall that includes peptidoglycan; and (ii) does not express a protein having the lytic transglycosylase activity of MltA protein. The invention also provides compositions comprising vesicles that, during culture of bacteria of the invention, are released into the culture medium. | 01-21-2010 |
20100056447 | IMMUNIZATION AGAINST CHLAMYDIA PNEUMONIAE - The published genomic sequence of | 03-04-2010 |
20100105865 | Nucleic acids and proteins from streptococcus groups a & b - The invention provides proteins from group B | 04-29-2010 |
20100136041 | COMBINATION GAS VACCINES AND THERAPEUTICS - Compositions useful for reducing the risk of, preventing, and/or treating | 06-03-2010 |
20100150943 | IMMUNOGENIC COMPOSITIONS FOR GRAM POSITIVE BACTERIA - The invention relates to the identification of a new adhesin islands within the genomes of several Gram positive | 06-17-2010 |
20100158935 | MUTANT FORMS OF STREPTOLYSIN O - Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against | 06-24-2010 |
20100215683 | PROTECTIVE ANTIGENS FOR GROUP B STREPTOCOCCUS HYPERVIRULENT STRAINS - The invention provides protective antigens for Group B streptococcus hypervirulent strains. The fragments are useful in vaccine compositions to induce protection against | 08-26-2010 |
20100272725 | Neisserial antigens - The invention provides proteins from | 10-28-2010 |
20110110857 | MUTANT FORMS OF CHLAMYDIA HTRA - An immunogenic | 05-12-2011 |
20110110967 | GAS57 MUTANT ANTIGENS AND GAS57 ANTIBODIES - The invention provides mutants of GAS57 which are unable to cleave IL-8 and similar substrates but which still maintain the ability to induce protection against | 05-12-2011 |
20110158977 | Immunogenic compositions for Chlamydia trachomatis - The present invention provides variant LcrE sequences and/or combinations of variant LcrE sequences across the | 06-30-2011 |
20110206692 | CONFORMERS OF BACTERIAL ADHESINS - The invention relates to isolated or purified bacterial adhesin conformers, preferably with improved stability and/or immunogenicity. In a preferred aspect, the invention comprises an isolated bacterial adhesin conformer F. Also provided are methods of isolation and/or separation of such adhesin conformers. The compositions may include one or more of the immunogenic polypeptides either alone or with other antigenic components. For example, the immunogenic polypeptides may be combined with other bacterial antigens to provide therapeutic compositions with broader range. | 08-25-2011 |
20120003258 | MUTANT FORMS OF STREPTOLYSIN O - Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against | 01-05-2012 |
20120034230 | Cna-B DOMAIN ANTIGENS IN VACCINES AGAINST GRAM POSITIVE BACTERIA - The invention provides protective antigens which are useful in vaccine compositions to induce protection against gram positive bacteria, particularly against | 02-09-2012 |
20120107322 | IMMUNOGENIC AND THERAPEUTIC COMPOSITIONS FOR STREPTOCOCCUS PYOGENES - Compositions for preventing and/or treating | 05-03-2012 |
20120141521 | Immunogenic Compositions for Streptococcus agalactiae - The invention relates to immunogenic polypeptides derived from epitopes in a | 06-07-2012 |
20120171236 | IMMUNIZATION AGAINST CHLAMYDIA PNEUMONIAE - The published genomic sequence of | 07-05-2012 |
20120207778 | NUCLEIC ACIDS AND PROTEINS FROM STREPTOCOCCUS GROUPS A AND B - The invention provides proteins from group B | 08-16-2012 |
20120219578 | NEISSERIAL ANTIGENIC PEPTIDES - This invention provides, among other things, proteins, polypeptides, and fragments thereof, derived from the bacteria | 08-30-2012 |
20120276129 | NEISSERIAL ANTIGENIC PEPTIDES - This invention provides, among other things, proteins, polypeptides, and fragments thereof, derived from the bacteria | 11-01-2012 |
20120276130 | DIAGNOSTIC AND THERAPEUTIC METHODS FOR RHEUMATIC HEART DISEASE BASED UPON GROUP A STREPTOCOCCUS MARKERS - This invention is in the field of identifying patients having rheumatic heart disease (RHD) associated with | 11-01-2012 |
20130005030 | GAS57 MUTANT ANTIGENS AND GAS57 ANTIBODIES - The invention provides mutants of GAS57 (Spy0416) which are unable to cleave IL-8 and similar substrates but which still maintain the ability to induce protection against | 01-03-2013 |
20130064846 | NEISSERIAL ANTIGENS - The invention provides proteins from | 03-14-2013 |
20140017727 | Cna-B DOMAIN ANTIGENS IN VACCINES AGAINST GRAM POSITIVE BACTERIA - The invention provides protective antigens which are useful in vaccine compositions to induce protection against gram positive bacteria, particularly against | 01-16-2014 |