Patent application number | Description | Published |
20090162371 | Anti-IL-23 Antibodies, Compositions, Methods and Uses - An anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 06-25-2009 |
20090239790 | NOVEL RECOMBINANT PROTEINS WITH N-TERMINAL FREE THIOL - The present invention relates to novel modified proteins having N-terminal free thiols that can be produced by recombinant methods and are ready for further chemical derivatization. In particular, the invention relates to erythropoietin conjugate compounds having altered biochemical, physiochemical and pharmacokinetic properties. More particularly, one embodiment of the invention relates to erythropoietin conjugate compounds of the formula: | 09-24-2009 |
20100183700 | IMPLANTABLE PUMP FOR PROTEIN DELIVERY FOR OBESITY CONTROL BY DRUG INFUSION INTO THE BRAIN - Methods and compositions are provided for suppressing appetite by surgically implanting a drug infusion pump into a site in a subject, and delivering a stable suspension of an appetite suppressing agent a region in a central nervous system of the subject. The appetite suppressing agent binds to a target receptor on a neural cell in the central nervous system and modifies the receptor function to suppress appetite. | 07-22-2010 |
20100322863 | Methods and Uses of Anti-IL-23 Antibodies - An anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 12-23-2010 |
20110040249 | Human Anti-IL-23 Antibodies, Compositions, Methods and Uses - A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 02-17-2011 |
20110195455 | Nucleic Acids Encoding Human Anti-IL-23 Antibodies - A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 08-11-2011 |
20110287028 | Methods of Treatment Using Human Anti-IL-23 Antibodies - A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 11-24-2011 |
20110319292 | METHODS FOR GENERATING ANTI-IL-23 ANTIBODIES, COMPOSITIONS, METHODS AND USES - A protein variant of IL-23p19 that has conserved residues in positions 93-102, 93-110, and/or 127-137 of SEQ ID NO:1, can be used to generate anti-IL-23p19 antibodies. | 12-29-2011 |
20120189643 | Toll Like Receptor 3 Antagonists, Methods and Uses - Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 07-26-2012 |
20120251454 | Human Anti-IL-23 Antibodies, Compositions, Methods and Uses - A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 10-04-2012 |
20120308573 | Anti-IL-23 Antibodies, Compositions, Methods and Uses - An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 12-06-2012 |
Patent application number | Description | Published |
20090186020 | Melanocortin Receptor Binding Mimetibodies, Compositions, Methods and Uses - Melanocortin receptor binding mimetibody polypeptides are disclosed. Polynucleotides encoding these polypeptides, cells comprising these polynucleotides or expressing the mimetibodies, and methods of making and using the forgoing are also disclosed. | 07-23-2009 |
20100166778 | Toll-Like Receptor 3 Antagonists - Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 07-01-2010 |
20110008352 | Toll-Like Receptor 3 Antagonists - Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 01-13-2011 |
20110200627 | ANTI-CD147 ANTIBODIES, METHODS AND USES - The present invention provides antibodies immunospecific for human CD 147 capable of blocking bioactivity of CD 147 associated with malignant disease such as the stimulation of MMPs from fibroblast cells by tumor cells, the release of VEGF, and the promotion of angiogenesis. The antibodies of the present invention of are useful in treating malignant disease and those diseases in which CD 147 activity is plays a pathogenic role, such as diseases of the eye, lung, and cardiovascular system. | 08-18-2011 |
20120064095 | TOLL-LIKE RECEPTOR 3 ANTAGONISTS FOR THE TREATMENT OF METABOLIC AND CARDIOVASCULAR DISEASES - Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 03-15-2012 |
20130090457 | Toll-Like Receptor 3 Antagonists for the Treatment of Metabolic and Cardiovascular Diseases - Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 04-11-2013 |
Patent application number | Description | Published |
20090150486 | SYSTEM AND METHOD FOR DELIVERING REMOTELY STORED APPLICATIONS AND INFORMATION - A method and system are disclosed for delivering interactive links for presenting applications and second information at a client computer from remote sources in a network-configured computer processing system. In one embodiment, the method includes retrieving over a first communication connection, in response to a request of a client computer, informational content having computer program code embedded therein, and executing the embedded computer program code for establishing a second communication connection to an application server. The method further includes retrieving over the second communication connection first information including presentational information for presenting the application and the second information. The method also includes presenting the application and the second information based upon the presentational information, and storing on the client computer an interactive link for selectively re-establishing the second communication connection to the application server for retrieving the first information and presenting the application and the second information on an as-needed basis. Preferably, the storing of the interactive link includes downloading a graphical representation of the interactive link and storing a file containing information representing an operating environment of the client computer and a network address of the application server. | 06-11-2009 |
20130024499 | SYSTEM AND METHOD FOR DELIVERING REMOTELY STORED APPLICATIONS AND INFORMATION - The computerized method and apparatus for mobile device interactivity includes hosting a network application on a server. The method and apparatus further includes receiving, at the application on the server, an event message from a mobile application executing on a mobile device, the application having executable code embedded therein for communicating with the network information for presenting a user interface for the network application on the mobile device, the event message reporting an action taken via the user interface. The method and apparatus further including executing application logic within the network application to generate data values based on the action reported in the event message and mobile device information and sending to the mobile device an update message with at least some of the generated data values and instructions for use by the executable code to present the data values within the user interface at the mobile device. | 01-24-2013 |
20140310333 | SYSTEM AND METHOD FOR DELIVERING REMOTELY STORED APPLICATIONS AND INFORMATION - The present invention includes computerized method and apparatus for user interactivity with a network application executing on a server. The method and apparatus includes receiving, via a wireless network, an event message from a mobile device, the event message representing an input from a user interface on the mobile device where the user interface is executing based on a mobile application. The method and apparatus further includes generating data values based on the input in the event message and information relating to the mobile device. Moreover, the method and apparatus includes sending an update message to the mobile device based on the data values for updating a display of the mobile device. | 10-16-2014 |
Patent application number | Description | Published |
20130244281 | Toll-Like Receptor 3 Antagonists - Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 09-19-2013 |
20130280263 | Toll-Like Receptor 3 Antagonists - Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 10-24-2013 |
20140017250 | Toll-Like Receptor 3 Antagonists for the Treatment of Metabolic and Cardiovascular Diseases - Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 01-16-2014 |
20140046031 | Anti-IL-23 Antibodies, Compositions, Methods and Uses - An anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 02-13-2014 |
20140079711 | ANTI-CD147 ANTIBODIES, METHODS AND USES - The present invention provides antibodies immunospecific for human CD147 capable of blocking bioactivity of CD147 associated with malignant disease such as the stimulation of MMPs from fibroblast cells by tumor cells, the release of VEGF, and the promotion of angiogenesis. The antibodies of the present invention of are useful in treating malignant disease and those diseases in which CD147 activity is plays a pathogenic role, such as diseases of the eye, lung, and cardiovascular system. | 03-20-2014 |
20140093508 | Toll-Like 3 Receptor Antagonists - Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 04-03-2014 |
20140128576 | Anti-IL-23 Antibodies, Compositions, Methods and Uses - An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 05-08-2014 |
20140212426 | Toll-Like Receptor 3 Antagonists - Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 07-31-2014 |
20140255388 | TOLL LIKE RECEPTOR 3 ANTAGONISTS, METHODS AND USES - Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments, and methods of making and using the foregoing are disclosed. | 09-11-2014 |