Patent application number | Description | Published |
20100282994 | Flow Bypass Manifold Including Drain - A flow bypass manifold including a drain comprising a fixed portion and an attachment portion for removable connection with the fixed portion. The fixed portion, fixedly installed into a fluidic system, defines a flow path and comprises inlet and outlet ports, a drain port, a bypass valve disposed in the flow path, a bypass outlet tube proximate the inlet port, and a bypass inlet tube proximate the outlet port. Two attachment tubes can be coupled to at least one flow-through series component and attached to the bypass outlet and inlet tubes to form an alternate flow path through the at least one flow-through, series component upon manipulation of the bypass valve to close the flow path through the fixed portion and divert the fluid to flow through the flow-through series component. This addition of a series component is accomplished without disassembling and/or reassembling the fluidic system or interrupting fluid flow. | 11-11-2010 |
20110247425 | Cartridge Fluid Transducer - There is provided a fluid transducer. The transducer housing includes a nose section, a middle section, and a rear section, with the nose section defining a through bore. A sensor is disposed in the nose section and is in fluid communication with the through bore. An electronic module is disposed in the middle section and is in electrical communication with the sensor. A cap is coupled to the real section of the transducer housing, with the cap configured to seal the rear section of the transducer housing. A conductor-insulator assembly is coupled to an outer surface of the transducer housing and the conductor of the conductor-insulator assembly is coupled to the electronic module. In one embodiment the conductor-insulator assembly is annular in shape, with an inside diameter corresponding to the outer surface of the transducer housing. | 10-13-2011 |
20110247431 | Cartridge Flow Transducer - There is provided a flow transducer and method to sense flow of a fluid. The flow transducer includes a housing defining an internal passage way therethrough. A flow rate apparatus is disclosed in the internal passageway. The proximity sensor is coupled to the housing, with the proximity sensor aligned radially with the flow rate apparatus. A pair of annular conductor-insulator assemblies are coupled to an outer surface of the housing, with each conductor in electrical communication with the proximity sensor. A cap is coupled to the housing and is configured to axially secure the conductor-insulator assemblies to the housing, with the cap defining an orifice axially aligned with the internal passageway. The proximity sensor is configured to produce an electrical signal as the flow rate apparatus rotates past the proximity sensor, the electrical signal corresponding to the flow of the fluid through the flow transducer. | 10-13-2011 |
Patent application number | Description | Published |
20090162355 | TREATMENT OF TUMORS USING SPECIFIC ANTI-L1 ANTIBODY - The present invention relates to the anti-L1 monoclonal antibody 9.3 as well as to related antibodies or binding molecules and well as to the uses thereof, especially in tumor treatment. | 06-25-2009 |
20120100161 | Amatoxin-Armed Therapeutic Cell Surface Binding Components Designed for Tumour Therapy - The invention relates to tumour therapy. In one aspect, the present invention relates to conjugates of a toxin and a target-binding moiety, e.g. an antibody, which are useful in the treatment of cancer. In particular, the toxin is an amatoxin, and the target-binding moiety is preferably directed against tumour-associated antigens. In particular, the amatoxin is conjugated to the antibody by linker moieties. In particular the linker moieties are covalently bound to functional groups located in positions of the amatoxin proved as preferred positions for the attachment of linkers with respect to optimum antitumor activity. In a further aspect the invention relates to pharmaceutical compositions comprising such target-binding moiety toxin conjugates and to the use of such target-binding moiety toxin conjugates for the preparation of such pharmaceutical compositions. The target-binding moiety toxin conjugates and pharmaceutical compositions of the invention are useful for the treatment of cancer. | 04-26-2012 |
20120213805 | Amatoxin-Armed Tartget-Binding Moieties for the Treatment of Cancer - The invention relates to tumour therapy. In one aspect, the present invention relates to conjugates of target-binding moieties and toxins that are useful in the treatment of cancer. In particular, the toxin is an amatoxin, and the target-binding moieties (e.g. antibodies) are directed against tumour-associated antigens, such as epithelial cell adhesion molecule (EpCAM). In a further aspect the invention relates to pharmaceutical compositions comprising such target-binding moiety toxin conjugates and to the use of such target-binding moiety toxin conjugates for the preparation of such pharmaceutical compositions. The target-binding moiety toxin conjugates and pharmaceutical compositions of the invention are useful for the treatment of cancer, in particular adenocarcinoma, such as pancreatic cancer, cholangiocarcinoma, breast cancer, and colorectal cancer. | 08-23-2012 |
20120258039 | TREATMENT OF TUMORS USING SPECIFIC ANTI-L1 ANTIBODY - The present invention relates to the anti-L1 monoclonal antibody 9.3 as well as to related antibodies or binding molecules and well as to the uses thereof, especially in tumor treatment. | 10-11-2012 |
20140120117 | TREATMENT OF TUMORS USING SPECIFIC ANTI-L1 ANTIBODY - The present invention relates to the anti-L1 monoclonal antibody 9.3 as well as to related antibodies or binding molecules and well as to the uses thereof, especially in tumor treatment. | 05-01-2014 |
20160089450 | AMATOXIN-ARMED THERAPEUTIC CELL SURFACE BINDING COMPONENTS DESIGNED FOR TUMOUR THERAPY - The invention relates to tumour therapy. In one aspect, the present invention relates to conjugates of a toxin and a target-binding moiety, e.g. an antibody, which are useful in the treatment of cancer. In particular, the toxin is an amatoxin, and the target-binding moiety is preferably directed against tumour-associated antigens. In particular, the amatoxin is conjugated to the antibody by linker moieties. In particular the linker moieties are covalently bound to functional groups located in positions of the amatoxin proved as preferred positions for the attachment of linkers with respect to optimum antitumor activity. In a further aspect the invention relates to pharmaceutical compositions comprising such target-binding moiety toxin conjugates and to the use of such target-binding moiety toxin conjugates for the preparation of such pharmaceutical compositions. The target-binding moiety toxin conjugates and pharmaceutical compositions of the invention are useful for the treatment of cancer. | 03-31-2016 |
Patent application number | Description | Published |
20140178444 | LONG CHAIN GLYCOLIPIDS USEFUL TO AVOID PERISHING OR MICROBIAL CONTAMINATION OF MATERIALS - The invention relates to the use of, and methods of use employing, certain glycolipid compounds as defined in detail below and having preservative or antimicrobial properties, novel compounds of the glycolipid class, and related invention embodiments. | 06-26-2014 |
20150133552 | POLYHYDROXYLATED PENTACYCLIC TRITERPENE ACIDS AS HMG-COA REDUCTASE INHIBITORS - The present invention relates to certain polyhydroxylated pentacyclic triterpene acids of formula (I) for use as HMG-CoA reductase inhibitors in the prophylactic and/or therapeutic treatment of a disease, disorder or condition that responds to a reduction of the HMG-CoA reductase activity in a mammal, preferably a human being. The present invention further relates to certain mixtures and plant extracts comprising euscaphic acid and tormentic acid, wherein the amount of euscaphic acid to tormentic acid exceeds a certain ratio. Further, the present invention also relates to a formulation, preferably pharmaceutical or nutraceutical formulation, comprising one or more of said compounds of formula (I), a composition according to the present invention or a plant extract according to the present invention. Also, the present invention relates to a process for obtaining certain polyhydroxylated pentacyclic triterpene acids of formula (I), a composition according to the present invention or a plant extract according to the present invention. | 05-14-2015 |
Patent application number | Description | Published |
20080276329 | Rice Cultivar CL171-AR - A rice cultivar designated CL171-AR is disclosed. The invention relates to the seeds of rice cultivar CL171-AR, to the plants of rice CL171-AR, to methods for producing a rice plant produced by crossing the cultivar CL171-AR with itself or another rice variety, and to methods for controlling weeds in the vicinity of plants of rice cultivar CL171-AR, which comprises increased resistance to acetohydroxyacid synthase-inhibiting herbicides. The invention further relates to hybrid rice seeds and plants produced by crossing the cultivar CL171-AR with another rice cultivar. | 11-06-2008 |
20110071024 | Rice Cultivar CL 142-AR - A rice cultivar designated CL 142-AR is disclosed. The invention relates to the seeds of rice cultivar CL 142-AR, to the plants of rice CL 142-AR, to methods for producing a rice plant produced by crossing the cultivar CL 142-AR with itself or another rice variety, and to methods for controlling weeds in the vicinity of plants of rice cultivar CL 142-AR, which comprises increased resistance to acetohydroxyacid synthase-inhibiting herbicides. The invention further relates to hybrid rice seeds and plants produced by crossing the cultivar CL 142-AR with another rice cultivar. | 03-24-2011 |
20110072534 | Rice Cultivar Templeton - A rice cultivar designated Templeton is disclosed. The invention relates to the seeds of rice cultivar Templeton, to the plants of rice cultivar Templeton, to plant parts of rice cultivar Templeton, and to methods for producing a rice plant produced by crossing rice cultivar Templeton with itself or with another rice variety. The invention also relates to methods for producing a rice plant containing in its genetic material one or more transgenes and to the transgenic rice plants and plant parts produced by those methods. This invention also relates to rice cultivars, or breeding cultivars, and plant parts derived from rice cultivar Templeton, to methods for producing other rice cultivars, lines or plant parts derived from rice cultivar Templeton, and to the rice plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid rice seeds, plants, and plant parts produced by crossing rice cultivar Templeton with another rice cultivar. | 03-24-2011 |
20110093976 | Rice Cultivar CL 181-AR - A rice cultivar designated CL 181-AR is disclosed. The invention relates to the seeds of rice cultivar CL 181-AR, to the plants of rice CL 181-AR, to methods for producing a rice plant produced by crossing the cultivar CL 181-AR with itself or another rice variety, and to methods for controlling weeds in the vicinity of plants of rice cultivar CL 181-AR, which comprises increased resistance to acetohydroxyacid synthase-inhibiting herbicides. The invention further relates to hybrid rice seeds and plants produced by crossing the cultivar CL 181-AR with another rice cultivar. | 04-21-2011 |
20120079619 | Rice Cultivar Roy J - A rice cultivar designated Roy J is disclosed. The invention relates to the seeds of rice cultivar Roy J, to the plants of rice cultivar Roy J, to plant parts of rice cultivar Roy J, and to methods for producing a rice plant produced by crossing rice cultivar Roy J with itself or with another rice variety. The invention also relates to methods for producing a rice plant containing in its genetic material one or more transgenes and to the transgenic rice plants and plant parts produced by those methods. This invention also relates to rice cultivars, or breeding cultivars, and plant parts derived from rice cultivar Roy J, to methods for producing other rice cultivars, lines or plant parts derived from rice cultivar Roy J, and to the rice plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid rice seeds, plants, and plant parts produced by crossing rice cultivar Roy J with another rice cultivar. | 03-29-2012 |
20120264604 | RICE CULTIVAR CL181-AR - A rice cultivar designated CL181-AR is disclosed. The invention relates to the seeds of rice cultivar CL181-AR, to the plants of rice CL181-AR, to methods for producing a rice plant produced by crossing the cultivar CL181-AR with itself or another rice variety, and to methods for controlling weeds in the vicinity of plants of rice cultivar CL181-AR, which comprises increased resistance to acetohydroxyacid synthase-inhibiting herbicides. The invention further relates to hybrid rice seeds and plants produced by crossing the cultivar CL181-AR with another rice cultivar. | 10-18-2012 |
20160081289 | RICE CULTIVAR LAKAST - A rice cultivar designated LaKast is disclosed. The invention relates to the seeds of rice cultivar LaKast, to the plants of rice cultivar LaKast, to plant parts of rice cultivar LaKast, and to methods for producing a rice plant produced by crossing rice cultivar LaKast with itself or with another rice variety. The invention also relates to methods for producing a rice plant containing in its genetic material one or more transgenes and to the transgenic rice plants and plant parts produced by those methods. This invention also relates to rice cultivars, or breeding cultivars, and plant parts derived from rice cultivar LaKast, to methods for producing other rice cultivars, lines or plant parts derived from rice cultivar LaKast, and to the rice plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid rice seeds, plants, and plant parts produced by crossing rice cultivar LaKast with another rice cultivar. | 03-24-2016 |
Patent application number | Description | Published |
20090188343 | OPERATING DEVICE HAVING RETAINED OPERATING LEVER - A vehicular operating device includes a lever movably attachable at one end to a housing such as a steering column such that the lever is pivotable relative to the housing between different positions. A connector connectable to the housing is adjacent to the first end of the lever and is in communication with the hollow body of the lever. A catch line having first and second ends runs through the hollow body of the lever with the first end of the catch line being connected to the connector and the second end of the catch line being connected to the second end of the lever. Upon the lever breaking, the catch line secures the lever to the connector as the catch line is connected to both of the second end of the lever and the connector to thereby prevent the lever from breaking away from the housing. | 07-30-2009 |
20090320634 | ELECTRIC SHIFTING DEVICE FOR A MOTOR VEHICLE - An electric shifting device for a vehicle includes a shift lever, a gate channel, and a detent device. The detent device has a spring-loaded pin and a detent contour cooperating therewith. The detent contour includes first and second paths and a connection path therebetween. The detent contour is movable relative to the channel between a first position in which the first path is aligned with the channel and a second position in which the second path is aligned with the channel. The lever is connected to the pin such that the lever is movable within the channel along the first path when the detent contour is in the first position and within the channel along the second path when the detent contour is in the second position and such that the lever is movable along the connection path between the paths when the detent contour moves between the positions. | 12-31-2009 |
20110207348 | STEERING COLUMN MODULE - An electrical device such as a steering column module for a vehicle includes a connector, a movable element, and a transport securing element movable to a position in which the transport securing element blocks the movable element from moving. When the transport securing element is in the position blocking the movable element from moving the transport securing element also blocks the connector from connecting with an external connection element. The transport securing element is movable to a position in which the transport securing element does not block the movable element from moving. When the transport securing element is in the position not blocking the movable element from moving the transport securing element also does not block the connector from connecting with an external connection element. | 08-25-2011 |
20110309827 | ANGLE SENSOR - An assembly for sensing the angular position of a rotatable shaft includes a bearing ring, a driving gear, and a measuring gear. The bearing ring is connectable to the shaft and has two recesses. The driving gear is rotatable about a rotational axis and has two entraining elements. The entraining elements extend radially toward the rotational axis of the driving gear and are arranged opposite one another with respect to the circumference of the driving gear. The entraining elements respectively penetrate into the recesses of the bearing ring such that the driving gear is connected to the bearing ring and rotates as the bearing ring rotates. The measuring gear is rotatable about a rotational axis and is engaged with the driving gear such that the measuring gear rotates as the driving gear rotates. One of the entraining elements is resilient. | 12-22-2011 |
20130093415 | Angle Sensor - An angle sensor for sensing angular position of a rotatable shaft includes a drive gear, a measuring gear, and a sensor housing. The drive gear is connected to the shaft. The measuring gear is driven by the drive gear. The angular position of the shaft can be determined from an angular position of the measuring gear. The sensor housing has a bearing for the drive gear. The drive gear and the measuring gear are rotationally mounted about respective axes of rotation in the sensor housing with the drive gear being inside the bearing. The drive gear is forcibly pressed into a radial position inside the bearing by at least one spring. | 04-18-2013 |
Patent application number | Description | Published |
20150284831 | Al-Mg ALLOY PRODUCT SUITABLE FOR ARMOUR PLATE APPLICATIONS - Aluminum alloy plate having improved resistance against incoming kinetic energy projectiles, the plate having a gauge of 10 mm or more and the aluminum alloy having a chemical composition including, in weight percent: Mg 4.0 to 6.0, Mn 0.2 to 1.4, Zn 0.9 max., Zr<0.3, Cr<0.3, Sc≦0.5, Ti≦0.3, Fe<0.5, Si<0.45, Ag<0.4, Cu<0.25, other elements and unavoidable impurities each <0.05, total <0.20, balance aluminum, and wherein the alloy plate is obtained by a manufacturing process including casting, preheating and/or homogenisation, hot rolling, a first cold working operation, an annealing treatment at a temperature of less than 350° C., followed by a second cold working operation. | 10-08-2015 |