Patent application number | Description | Published |
20130137652 | COMBINATION OF A PYRROLOQUINOLINE COMPOUND AND AN AMINOGLYCODISE ANTIMICROBIAL AGENT - This invention relates to the use of 4-methyl-8-phenoxy-1-(2-phenylethyl)-2,3-dihydro-1H-pyrrolo[3,2-c]quinoline or a pharmaceutically acceptable derivative thereof in combination with an aminoglycoside antimicrobial agent for the prevention and/or treatment of microbial infections. | 05-30-2013 |
20130184230 | COMBINATION OF A PYRROLOQUINOLINE COMPOUND AND A BETA-LACTAM ANTIMICROBIAL AGENT, MUPIROCIN OR CHLORHEXIDINE - This invention relates to the use of 4-methyl-8-phenoxy-1-(2-phenylethyl)-2,3-dihydro-1H-pyrrolo[3,2-c]quinoline or a pharmaceutically acceptable derivative thereof in combination with another antimicrobial agent selected from the group consisting of a beta-lactam antimicrobial agent, mupirocin and chlorhexidine or a pharmaceutically acceptable derivative thereof, for the prevention and/or treatment of microbial infections. | 07-18-2013 |
20130243886 | NOVEL USE - The present invention relates to the use of one or more compounds selected from the following classes of biologically active agents: an a-adrenergic antagonist, an anthelmintic agent, an antifungal agent, an antimalarial agent, an antineoplastic agent, an antipsychotic agent, an antioxidant, a vasodilator and/or a vitamin, or a pharmaceutically acceptable derivative thereof, for use in the treatment of a microbial infection and in particular for killing multiplying, non-multiplying and/or clinically latent microorganisms associated with such an infection. | 09-19-2013 |
20130245060 | NOVEL COMPOSITION - This invention relates to topical pharmaceutical compositions comprising the active agent 4-methyl-1-(2-phenylethyl)-8-phenoxy-2,3-dihydro-1H-pyrrolo[3,2-c]-quinoline or a pharmaceutically acceptable derivative thereof and a hydrophobic excipient, to a process for preparing such compositions, and to the use of such compositions for the treatment of microbial infections. | 09-19-2013 |
20160082073 | NOVEL USE - The present invention relates to a combination comprising at least one compound selected from the group consisting of an α-adrenergic antagonist, an anthelmintic agent, an antifungal agent, an antimalarial agent, an antineoplastic agent, an antipsychotic agent, an antioxidant, a vasodilator, a vitamin, or a pharmaceutically acceptable derivative thereof; and an antimicrobial compound. | 03-24-2016 |
Patent application number | Description | Published |
20090104651 | SCREENING PROCESS FOR ANTIBACTERIAL AGENTS - The present invention relates to a method of preparing a phenotypically antibiotic-resistant subpopulation of stationary phase bacteria by treating stationary phase bacteria with high doses of antibacterial agents, the subpopulation thus identified, a process for identifying new antibacterial agents by testing against the antibiotic-resistant subpopulation, the compounds thus identified and their uses, particularly in treating bacterial infections involving dormant bacteria. | 04-23-2009 |
20110052616 | Biological materials and uses thereof - The present invention concerns a peptide molecule or a nucleic acid molecule, for use in medicine and, in particular, for use in preventing or treating a non-cancerous condition or relieving pain in a patient. The invention also relates to a pharmaceutical composition comprising the peptide or nucleic acid molecule of the invention and methods of treatment thereof. | 03-03-2011 |
20140341932 | Novel pepetides - The present invention relates to novel peptides derivable from the polypeptide chaperonin 60.1 and to their use in medicine, such as for the prevention and/or treatment of inflammatory conditions. | 11-20-2014 |
Patent application number | Description | Published |
20120267291 | Pressure Sensor - A pressure sensor for a dialysis machine, the sensor having a body and a sensing surface, the sensor surface configured to detect the pressure of a fluid across an elastic membrane, the sensor in use generating a vacuum between the sensing surface and the membrane so as to draw the membrane into contact with the sensing surface, wherein the elastic membrane is further retained in use between a sealing surface on the dialysis machine and a membrane engaging surface on the body of the sensor. | 10-25-2012 |
20120269907 | Dialysis Machine Control - A method of preparing a dialysate solution for hemodialysis, the method including the steps of providing a mixing pump comprising a pump chamber covered by an actuable membrane, the chamber having a first inlet for admitting water into the chamber, a second inlet for admitting dialysate base solution into the chamber, and an outlet from the chamber, the method including the further steps of providing pump means for dispensing a predetermined volume of dialysate solution base into the chamber at a first pressure, actuating the membrane to draw a volume of water or water mix into the mixing pump chamber at a second pressure, wherein the magnitude of the first pressure is higher than the magnitude of the second pressure so as to ensure the complete dispense of the dialysate solution base into the chamber. | 10-25-2012 |
20120275943 | Pump - A pump for a dialysis machine, the pump having a pump chamber and a deformable membrane actuable to pump a fluid from the pump chamber, the pump chamber being substantially conical such that the membrane is actuated to extend into the conical chamber in order to pump the fluid from the chamber. | 11-01-2012 |
Patent application number | Description | Published |
20090117127 | Novel Compounds and Methods for Their Production - The present invention relates to 11-O-desmethylmacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies. | 05-07-2009 |
20090209507 | 15-O-Desmethylmacbecin Derivatives and Their Use in the Treatment of Cancer or B-Cell Malignancies - The present invention relates to 15-O-desmethylmacbecin analogues according to the formula (IA) or (IB) herein, or a pharmaceutically acceptable salt thereof: wherein: R | 08-20-2009 |
20090253667 | 18 ,21-Didesoxymacbecin Derivatives for the Treatment of Cancer - The present invention relates to 18,21-didesoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pre-treatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies. | 10-08-2009 |
20090298804 | Novel Compounds and Methods for Their Production - The present invention relates to 15-desmethoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies. | 12-03-2009 |
20100068203 | 17-Oxymacbecin Derivatives and Their Use in the Treatment of Cancer and/or B-Cell Malignancies - The present invention relates to 17-oxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies. | 03-18-2010 |
20110091452 | 4,5-Dihydromacbecin Derivatives and Their Use in the Treatment of Cancer or B-Cell Malignancies - The present invention relates to 4,5-dihydromacbecin analogues to the formula (IA) or (IB), or a pharmaceutically acceptable salt there of: wherein: R | 04-21-2011 |
20110160175 | 18,21-Didesoxymacbecin Derivatives for the Treatment of Cancer - The present invention relates to macbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pre-treatment for cancer. The present invention also provides methods for the production of these compounds involving incorporation of non-natural starter units and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies. | 06-30-2011 |
Patent application number | Description | Published |
20080287576 | LOW DENSITY ORIENTED POLYMER COMPOSITION WITH INERT INORGANIC FILLER - An oriented polymer composition containing thirty to 95 weight-percent inert inorganic filler and a continuous phase of at least one orientable polymer contains void spaces due to cavitation and has a density of less than 0.8 grams per cubic centimeter, a flexural modulus of 1.4 gigapascals or more, cross section dimensions all greater than 1.5 millimeters, a delamination force value of 44.5 Newtons (ten pounds force) or more and little or no blowing agent. | 11-20-2008 |
20100301511 | LOW DENSITY ORIENTED POLYMER COMPOSITION WITH INERT INORGANIC FILLER - An oriented polymer composition containing thirty to 95 weight-percent inert inorganic filler and a continuous phase of at least one orientable polymer contains void spaces due to cavitation and has a density of less than 0.8 grams per cubic centimeter, a flexural modulus of 1.4 gigapascals or more, cross section dimensions all greater than 1.5 millimeters, a delamination force value of 44.5 Newtons (ten pounds force) or more and little or no blowing agent. | 12-02-2010 |
20120121879 | LOW DENSITY ORIENTED POLYMER COMPOSITION WITH INERT INORGANIC FILLER - An oriented polymer composition containing thirty to 95 weight-percent inert inorganic filler and a continuous phase of at least one orientable polymer contains void spaces due to cavitation and has a density of less than 0.8 grams per cubic centimeter, a flexural modulus of 1.4 gigapascals or more, cross section dimensions all greater than 1.5 millimeters, a delamination force value of 44.5 Newtons (ten pounds force) or more and little or no blowing agent. | 05-17-2012 |
20140162046 | LOW DENSITY ORIENTED POLYMER COMPOSITION WITH INERT INORGANIC FILLER - An article of manufacture comprising a polymer composition, having 30 wt % or more and 95 wt % or less inert inorganic filler, that is oriented by the steps of conditioning the polymer composition to a drawing temperature of at least 15° C. and approximately 40° C. below a softening temperature of the polymer composition; and drawing the polymer composition though a drawing die at a drawing rate of at least 0.25 m/min and with a nominal draw ratio of 1.25 or more and 8 or less to produce the article of manufacture made of the oriented polymer composition. | 06-12-2014 |
Patent application number | Description | Published |
20140001415 | Methods to Improve the Electrical Conductivity for Moulded Plastic Parts | 01-02-2014 |
20140309691 | MEDICAL DEVICES CONTAINING SHAPE MEMORY POLYMER COMPOSITIONS - The present invention relates at least in part to surgical devices which comprise a shape memory polymer material composition. Particularly, although not exclusively, the present invention relates to a fixation device e.g. an anchor device e.g. a suture anchor which comprises a shape memory material. Included in the present invention are anchor devices e.g. suture anchors which are formed entirely of a shape memory polymer material. Embodiments of the present invention comprise hybrid suture anchors, particularly suture anchors which are formed from a shape memory polymer material and a non-shape memory material. Methods of securing an anchor in a bone or tissue are also included in the present invention. | 10-16-2014 |
20150073476 | SHAPE MEMORY POLYMER COMPOSITIONS - The present invention relates to compositions comprising shape memory polymer (SMP) materials and uses thereof. Particularly, although not exclusively, the present invention relates to biocompatible shape memory polymer (SMP) materials and uses thereof in the medical field. | 03-12-2015 |
20150123314 | PROCESS FOR THE MANUFACTURE OF SHAPE MEMORY POLYMER MATERIAL - The present invention relates at least in part to methods for the manufacture of shape memory polymer (SMP) materials. Particularly, although not exclusive, the present invention relates to processes for the formation of complex shaped devices composed of shape memory polymer. | 05-07-2015 |
Patent application number | Description | Published |
20110226267 | Transgenic Plants - The invention provides transgenic plants, specifically tobacco plants, which accumulate the amino acid threonine in their leaves. The biosynthetic pathway leading to production of threonine is tightly regulated, and previous attempts to achieve a transgenic plant which overproduces threonine has compromised the fitness of the plants. This invention has overcome these difficulties and found a method of increasing the level of threonine in plant leaves above the corresponding wild type level without compromising plant fitness, comprising altering plant metabolism to achieve increased production of threonine after the initiation of leaf senescence. This invention involves a genetic construct comprising a senescence specific promoter operably linked to a coding sequence encoding a polypeptide having threonine insensitive aspartate kinase activity. | 09-22-2011 |
20120199144 | Transgenic Plants - The invention provides transgenic plants, specifically tobacco plants, which accumulate the amino acid threonine in their leaves. The biosynthetic pathway leading to production of threonine is tightly regulated, and previous attempts to achieve a transgenic plant which overproduces threonine has compromised the fitness of the plants. This invention has overcome these difficulties and found a method of increasing the level of threonine in plant leaves above the corresponding wild type level without compromising plant fitness, comprising altering plant metabolism to achieve increased production of threonine after the initiation of leaf senescence. This invention involves a genetic construct comprising a senescence specific promoter operably linked to a coding sequence encoding a polypeptide having threonine insensitive aspartate kinase activity. | 08-09-2012 |
20150296872 | TREATMENT OF TOBACCO MATERIAL - A method is provided for treating a tobacco material, comprising treating the tobacco material with an ionic liquid. Also provided is a tobacco material which has been treated by such a method, or a derivative thereof, and a smoking article which comprises a tobacco material treated by such a method. | 10-22-2015 |
20150296873 | TREATMENT OF TOBACCO MATERIAL - A method is provided for treating a tobacco material, comprising treating the tobacco material by steam hydrolysis. Also provided is a tobacco material which has been treated by such a method, or a derivative thereof, and a smoking article which comprises a tobacco material treated by such a method. | 10-22-2015 |