Patent application number | Description | Published |
20090010924 | Apoptotic Anti-IgE Antibodies - The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders. | 01-08-2009 |
20100143352 | COMBINATION THERAPY FOR B CELL DISORDERS - The invention provides methods of treating B cell based malignancies and B-cell regulated autoimmune disorders using a combination therapy of anti-CD20 antibody with a BLyS antagonist. | 06-10-2010 |
20100247430 | Methods and Compositions for Modulating T Cells - The invention provides methods and compositions useful for modulating T cells, and disorders associated with the dysregulation thereof. | 09-30-2010 |
20120144512 | TRANSGENIC ANIMALS EXPRESSING HUMAN IGE-M1' - The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders. | 06-07-2012 |
20120149881 | APOPTOTIC ANTI-IGE ANTIBODIES - The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders. | 06-14-2012 |
20120178127 | Nucleic acid encoding apoptotic anti-ige antibodies - The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders. | 07-12-2012 |
20140115729 | APOPTOTIC ANTI-IGE ANTIBODIES - The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders. | 04-24-2014 |
20140377257 | COMBINATION THERAPY FOR B CELL DISORDERS - The invention provides methods of treating B cell based malignancies and B-cell regulated autoimmune disorders using a combination therapy of anti-CD20 antibody with a BLyS antagonist. | 12-25-2014 |
Patent application number | Description | Published |
20100305096 | BICYCLIC PYRIMIDINE PI3K INHIBITOR COMPOUNDS SELECTIVE FOR P110 DELTA, AND METHODS OF USE - Formula I (Ia and Ib) compounds wherein (i) X | 12-02-2010 |
20110201599 | CDK Modulators - A compound according to Formula I: or a pharmaceutically-acceptable salt thereof, wherein R1, R3, A, B and D are as defined in the specification; pharmaceutical compositions thereof, and methods of use thereof. | 08-18-2011 |
20110207713 | PYRIDO[3,2-d]PYRIMIDINE PI3K DELTA INHIBITOR COMPOUNDS AND METHODS OF USE - Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. | 08-25-2011 |
20120178736 | BICYCLIC PYRIMIDINE PI3K INHIBITOR COMPOUNDS SELECTIVE FOR P110 DELTA, AND METHODS OF USE - Formula I (Ia and Ib) compounds wherein (i) X | 07-12-2012 |
20130225557 | PYRIDO[3,2-d]PYRIMIDINE PI3K DELTA INHIBITOR COMPOUNDS AND METHODS OF USE - Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. | 08-29-2013 |
20140288043 | PYRAZOLOPYRIDINE COMPOUNDS - A first aspect of the invention relates to a compound of formula (1A) or (1B), or a pharmaceutically acceptable salt thereof, | 09-25-2014 |
Patent application number | Description | Published |
20080285247 | Low Exothermic Thermosetting Resin Compositions Useful As Underfill Sealants and Having Reworkability - This invention relates to the thermosetting resin compositions useful for mounting onto a circuit board semiconductor devices, such as chip size or chip scale packages (“CSPs”), ball grid arrays (“BGAs”), land grid arrays (“LGAs”) and the like, each of which having a semiconductor chip, such as large scale integration (“LSI”), on a carrier substrate. Similarly, the compositions are useful for mounting onto circuit board semiconductor chips themselves. Reaction products of the compositions of this invention are controllably reworkable when subjected to appropriate conditions. And significantly, unlike many commercial rapid curing underfill sealants (“snap cure underfills”), the inventive compositions possess an exotherm under 300 J/g or demonstrate package stability at 55° C. for 7 days, and therefore do not require special packaging to be transported by air courier, or special approval from international transportation authorities, such as the U.S. Department of Transportation, to permit such air transport. The inventive compositions possess an exotherm under 300 J/g and/or demonstrate package stability at 55° C. for 7 days and therefore do not require special packaging to be transported by air courier, or special approval from international transportation authorities, such as the U.S. Department of Transportation, to permit such air transport. | 11-20-2008 |
20110065242 | METHOD OF FABRICATING A SEMICONDUCTOR PACKAGE USING A FLUXING UNDERFILL COMPOSITION APPLIED TO SOLDER BALLS IN A DIP PROCESS - The present invention relates to a method of fabricating a semiconductor package or circuit assembly using an fluxing underfill composition applied to solder contact points in a dip process. | 03-17-2011 |
Patent application number | Description | Published |
20100196397 | Five-helix protein - Five-Helix protein, which comprises the three N-helices and at least two, but not three, of the three C-helices of the trimer-of-hairpin structure of HIV gp41, separated by linkers, such as amino acid residue linkers, is disclosed. Six-Helix protein, which includes the three N-helices and the three C-helices of the trimer-of-hairpin structure of HIV gp41, separated by linkers, is also disclosed. | 08-05-2010 |
20130347135 | ANIMAL MODEL FOR PARKINSON'S DISEASE - An animal model for Parkinson's disease has a disrupted Mfn2 gene in dopaminergic neurons. | 12-26-2013 |
20140024066 | ANIMAL MODEL HAVING PHOTO-ACTIVATABLE MITOCHONDRIA - An animal model includes a photo-activatable fluorescent protein that can conditionally label the mitochondria throughout the animal or in selective animal cells and tissues, allowing for effective studying of the mitochondria and tracking of mitochondrial dynamics. | 01-23-2014 |
Patent application number | Description | Published |
20110041672 | METHOD AND SYSTEM FOR MIDI CONTROL OVER POWERLINE COMMUNICATIONS - An apparatus for processing one or more MIDI signals into a powerline format. The apparatus has an input port configured to receive a first digital signal having a MIDI format. The apparatus also has one or more powerline modules configured to process at least the digital signal in the MIDI format to a second digital signal in a powerline format. The apparatus also has an output port configured to transfer the second digital signal. | 02-24-2011 |
20130046412 | METHOD AND SYSTEM FOR INTELLIGENT ENERGY NETWORK MANAGEMENT CONTROL SYSTEM - A system for providing network infrastructure for energy management and control is disclosed. A controller integrates powerline and wireless networking technologies in order to provide an integrated network. A gateway sends and receives command and control data across the integrated network. Client devices may connect to the integrated network and perform a variety of functions. An appliance module may send and receive data across the integrated network in relation to a particular appliance. A panel meter may send and receive data across the integrated network in relation to data measured at a distribution panel. A serial bridge may connect various devices to the integrated network. Computing devices may remotely or locally connect to the integrated network and send and receive data. | 02-21-2013 |
20130117584 | METHOD AND SYSTEM FOR ISOLATING LOCAL AREA NETWORKS OVER A CO-AXIAL WIRING FOR ENERGY MANAGEMENT - An energy management system. The system includes a coax controller apparatus comprising an exterior housing and plurality of coax modules numbered from 2 through N, where N is an integer greater than 3. In a specific embodiment, each of the coax modules comprises a powerline chip (PLC) module coupled to an analog front end, which is coupled to a coaxial connector. The system also has an electromagnetic shield configured to each of the coax modules. In a specific embodiment, the electromagnetic shield is configured to substantially maintain the coax module substantially free from interference noise or other disturbances. The system has a power meter coupled to one or more ports of the coax controller apparatus. | 05-09-2013 |
20130154850 | METHOD AND SYSTEM FOR AUTOMATED POWER METER INFRASTRUCTURE - A system for extending the Smart Meter's range to connect to Home Area Networks for energy monitoring and demand response in a variety of locations. The system has a data concentrator with a wireless communicating module configured to transmit and receive information at one or more first frequencies ranging up to 2.4 GHz, and a power-line module configured to transmit and receive information at one or more frequencies ranging from about 100 to 30 MHz. The data concentrator receives power information from one or more Smart Meters and convert the wireless signal to a power-line carrier signal over the existing all three phases of the AC wiring. The system also includes a wireless and power-line carrier bridge that converts the power-line carrier signal back to a wireless signal to connect to various Home Area Network (HAN) devices such as programmable communicating thermostats (PCTs), smart appliances and in-home displays (IHDs). | 06-20-2013 |
20140176340 | METHOD AND SYSTEM FOR POWERLINE TO MESHED NETWORK FOR POWER METER INFRA-STRUCTURE - A transparent networking system for meter infrastructure within a network. The system has a single transparent meshed communication network comprising a first ZigBee network provided within a first spatial region and a second ZigBee network provided within a second spatial region. The network has a powerline carrier configured between the first ZigBee network and the second ZigBee network to facility transfer of bi-directional information packet by packet between the first ZigBee network and the second ZigBee networks. | 06-26-2014 |
Patent application number | Description | Published |
20090131873 | SYSTEM AND METHOD FOR POSITIONING IMPLANTABLE MEDICAL DEVICES WITHIN CORONARY VEINS - An improved system and method for placing implantable medical devices (IMDs) such as leads within the coronary sinus and branch veins is disclosed. In one embodiment, a slittable delivery sheath and a method of using the sheath are provided. The sheath includes a slittable hub, and a substantially straight body defining an inner lumen. The body comprises a shaft section and a distal section that is distal to, and softer than, the shaft section. A slittable braid extends adjacent to at least a portion of one of the shaft section and the distal section. In one embodiment of the invention, the sheath further includes a transition section that is distal to the shaft section, and proximal to the distal section. The transition section is softer than the shaft section, but stiffer than the distal section. | 05-21-2009 |
20140343549 | SYSTEM AND METHOD FOR POSITIONING IMPLANTABLE MEDICAL DEVICES WITHIN CORONARY VEINS - An improved system and method for placing implantable medical devices (IMDs) such as leads within the coronary sinus and branch veins is disclosed. In one embodiment, a slittable delivery sheath and a method of using the sheath are provided. The sheath includes a slittable hub, and a substantially straight body defining an inner lumen. The body comprises a shaft section and a distal section that is distal to, and softer than, the shaft section. A slittable braid extends adjacent to at least a portion of one of the shaft section and the distal section. In one embodiment of the invention, the sheath further includes a transition section that is distal to the shaft section, and proximal to the distal section. The transition section is softer than the shaft section, but stiffer than the distal section. | 11-20-2014 |
Patent application number | Description | Published |
20090240249 | System and Method for Performing Ablation and Other Medical Procedures Using An Electrode Array with Flexible Circuit - A probe for use in medical procedures includes a longitudinal member, a flexible sheath, and a flexible circuit. The longitudinal member includes at least one electrode and at least one thermocouple disposed thereon. The flexible sheath is coupled to and at least partially surrounding the longitudinal member. The flexible circuit is coupled to the sheath and also to the at least one electrode and the at least one thermocouple. The flexible circuit is configured to provide power to the at least one electrode and a return path to the at least one thermocouple. | 09-24-2009 |
20090275939 | Ablation probe with stabilizing member - A surgical ablation probe assembly particularly suitable for ablating tissue on a surface of a patient's heart having an ablation member and a stabilizing member for guiding the probe assembly to an intracorporeal location such as a surface of the patient's heart. The elongated ablation member generally has at least one ablation electrode on a distal shaft section. The stabilizing member has a vacuum lumen which applies a vacuum to the inner chamber of the stabilizing member to aspirate fluid from within the chamber or about the stabilizing member and can aid in holding the stabilizing member to an intracorporeal surface such as the epicardial or endocardial surface of the patient's heart. The probe assembly may also have a removable stylet to help retain the shape of the distal portion. The assembly is suitable for treating a patient for atrial arrhythmia, by forming linear or curvilinear lesions and preferably a continuous lesion on the surface of the patient's heart. | 11-05-2009 |
20120293340 | TRIGGERING RECHARGING AND WIRELESS TRANSMISSION OF REMOTE PATIENT MONITORING DEVICE - Applicant has disclosed a convenient method of automatic identification, communication with, and battery life extension and automatic recharging for a medical telemetry device, worn by a patient. Applicant's preferred method in its broadest sense comprises: once a patient puts the medical telemetry device into or near a base unit for charging, the device automatically starts communicating physiological data via the Internet to clinicians and/or remote servers for analysis. | 11-22-2012 |
20130204096 | Medical Device with a Deflectable Shaft Section and Tension Control - A catheter comprises an elongated shaft having a proximal shaft section and a shapeable shaft section distal to the proximal section, an inner lumen extending within the proximal and shapeable shaft sections; a shaping member slidably disposed within the inner lumen and extends into the shapeable shaft section; a shape memory member adjacent to the shaping member in the inner lumen of the shapeable shaft section, wherein the shaping member and the shape memory member are coupled by a coupling coil; and a handle having an operating lever, wherein the handle receives the proximal shaft section and the shaping member for operating the shapeable shaft section. | 08-08-2013 |
Patent application number | Description | Published |
20100260679 | METHOD AND APPARATUS FOR DETECTING AND REGULATING VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) BY FORMING A HOMEOSTATIC LOOP EMPLOYING A HALF-ANTIBODY BIOSENSOR - A biosensor for detection of vascular endothelial growth factor (VEGF) hybridization uses an array of parallel capacitors to detect electrochemical binding of circulating VEGF to immobilized anti-VEGF monoclonal half-antibodies (a-VEGF mhAb). Binding of a-VEGF mhAb modulates the threshold voltage of a circuit, changing the impedance of the circuit. An electrode coated with a p-Si substrate enhances the affinity between the VEGF molecules. A fluid cell delivers VEGF samples onto the active surface of the chip. An array of parallel capacitors arranged in an interdigitated pattern detects the VEGF in the fluid. The detector provides an accurately measured and quantifiable rate of change of the VEGF molecules in vivo, providing real time feedback which is used to measure response of the tumor to delivered chemotherapeutic agents and biological response modifiers (BRMs) for the purpose of determining tumor burden and efficacy of the chemotherapy as part of a homeostatic loop for chemotherapy. | 10-14-2010 |
20110092948 | Remotely Activated Piezoelectric Pump for Delivery of Biological Agents to the Intervertebral Disc and Spine - The present disclosure describes a remotely activated piezoelectric pump for delivery of biological agents to the intervertebral disc and spine in order to achieve spinal fusion. A spinal pump is implanted on the vertebrae of a patient and a spinal cage is inserted in between two adjacent vertebrae after removal of the vertebrae disc. A piezoelectric motor drives the pump and pushes osteogenetic agent through the spinal cage and into a sponge disposed within the cage. The pump is charged by an external removable induction belt worn by the patient. Delivery duration and delivery frequency may be changed before implantation of the spine pump according to the specific needs of the patient. The current device employs a mathematical model that enables the regulation as well as attenuation of the bone fusion process by extending and generalizing the model to enhance and optimize the delivery of osteogenetic agent in a regulated manner. | 04-21-2011 |
20110162979 | Method and Apparatus for Forming of an Automated Sampling Device for the Detection of Salmonella Enterica Utilizing an Electrochemical Aptamer Biosensor - An aptamer-based solid-state electrochemical biosensor for label-free detection of | 07-07-2011 |
20110166033 | Method and Apparatus for Forming of an Automated Sampling Device for the Detection of Salmonella Enterica Utilizing an Electrochemical Aptamer Biosensor - An aptamer-based solid-state electrochemical biosensor for label-free detection of | 07-07-2011 |
20110295159 | Method and Apparatus for an Implantable Inertial-Based Sensing System for Real-Time, In Vivo Detection of Spinal Pseudarthrosis and Adjacent Segment Motion - A vertebral processor designed to collect and interpret data from multiple surgically implanted accelerometers. Each accelerometer is surgically implanted into a vertebra of a patient utilizing a bone screw. Additional accelerometers are implanted in adjacent vertebrae. The data from the accelerometers is compared by an algorithm to determine the relative movement of the accelerometers implanted in adjacent vertebrae. Data is generated via the algorithm and compared against the expected behavior of the surgically implanted accelerometers as if they were connected to a rigid body, thus determining the level of success of a spinal fusion procedure for those adjacent segments. The apparatus may be utilized with or without spinal stabilization hardware, and with or without fusion cages or artificial discs. The vertebral processor is supplemented by an external system worn by the patient, which provides for an inductive charging power source and for data transfer. | 12-01-2011 |
20120041562 | Remotely Activated Piezoelectric Pump for Delivery of Biological Agents to the Intervertebral Disc and Spine - A remotely activated piezoelectric pump for delivery of biological agents to the intervertebral disc and spine in order to achieve spinal fusion. A spinal pump is implanted on the vertebrae of a patient and a spinal cage is inserted in between two adjacent vertebrae after removal of the vertebrae disc. A piezoelectric motor drives the pump and pushes osteogenetic agent through the spinal cage and into a sponge disposed within the cage. The pump is charged by an external removable induction belt worn by the patient. Delivery duration and delivery frequency may be changed before implantation of the spine pump according to the specific needs of the patient. The current device employs a mathematical model that enables the regulation as well as attenuation of the bone fusion process by extending and generalizing the model to enhance and optimize the delivery of osteogenetic agent in a regulated manner. | 02-16-2012 |
Patent application number | Description | Published |
20100235077 | Historical data based navigational routing - Navigational routing is generated incorporating an estimation of future traffic conditions. The future traffic conditions are estimated based on historical traffic data, e.g., obtained over a recent period of time. The system provides navigational routing based on historical traffic data incorporated into a calculated route of travel. The historical data is used to calculate a probability that given roads along the route will be problematic at a certain time of the day, i.e., at the time, day of week, and place that you would be expected to be traveling on that certain road. Accordingly, historical traffic data is used to help determine a best route based on the probability of certain roads being problematic at a certain time of day. | 09-16-2010 |
20140032096 | Historical Data Based Navigational Routing - Navigational routing is generated incorporating an estimation of future traffic conditions. The future traffic conditions are estimated based on historical traffic data, e.g., obtained over a recent period of time. The system provides navigational routing based on historical traffic data incorporated into a calculated route of travel. The historical data is used to calculate a probability that given roads along the route will be problematic at a certain time of the day, i.e., at the time, day of week, and place that you would be expected to be traveling on that certain road. Accordingly, historical traffic data is used to help determine a best route based on the probability of certain roads being problematic at a certain time of day. | 01-30-2014 |
Patent application number | Description | Published |
20090161595 | SYSTEM AND METHOD FOR BROADCASTING APPLICATION-SPECIFIC INFORMATION IN WIRELESS LOCAL AREA NETWORKS - A system and method for a novel broadcasting scheme (NBS) in a wireless local area network are described, which can operate with or without a network connection. The system permits transmission of application-specific data through a specific field in a beacon frame, the Service Set Identity (SSID). By implementing a NBS Processor in an AP and a NBS Parser in stations, the AP can broadcast application-specific data while the stations can automatically act upon the receipt of the broadcast. | 06-25-2009 |
20110078253 | SYSTEM AND METHOD FOR COMMUNICATING OVER A NETWORK WITH A MEDICAL DEVICE - A medical device is provided that performs a requested action. The requested action may be communicated, for example, to the medical device via email messages. After performing the requested action, a response that is dependent upon the requested action is generated. The generated response is then sent on a network from the medical device as an email message. | 03-31-2011 |
20110179123 | SYSTEM AND METHOD FOR COMMUNICATING OVER A NETWORK WITH A MEDICAL DEVICE - A device is provided for connecting a medical apparatus to a network. The device collects data from the medical apparatus and performs a variety of processing functions, such as trending, protocol translation, generating reports, etc. related to the collected data. The device then transmits the collected data over a network to interested parties. In some implementations, the device can transmit the collected data as an email message. | 07-21-2011 |
20110219090 | SYSTEM AND METHOD FOR COMMUNICATING OVER A NETWORK WITH A MEDICAL DEVICE - A device is provided for connecting a medical apparatus to a network. The device collects data from the medical apparatus and performs a variety of processing functions, such as trending, protocol translation, generating reports, etc. related to the collected data. The device then transmits the collected data over a network to interested parties. In some implementations, the device can transmit the collected data as an email message. | 09-08-2011 |
20110219091 | SYSTEM AND METHOD FOR COMMUNICATING OVER A NETWORK WITH A MEDICAL DEVICE - A device is provided for connecting a medical apparatus to a network. The device collects data from the medical apparatus and performs a variety of processing functions, such as trending, protocol translation, generating reports, etc. related to the collected data. The device then transmits the collected data over a network to interested parties. In some implementations, the device can transmit the collected data as an email message. | 09-08-2011 |
20110231504 | SYSTEM AND METHOD FOR COMMUNICATING OVER A NETWORK WITH A MEDICAL DEVICE - A device is provided for connecting a medical apparatus to a network. The device collects data from the medical apparatus and performs a variety of processing functions, such as trending, protocol translation, generating reports, etc. related to the collected data. The device then transmits the collected data over a network to interested parties. In some implementations, the device can transmit the collected data as an email message. | 09-22-2011 |
20110231505 | SYSTEM AND METHOD FOR COMMUNICATING OVER A NETWORK WITH A MEDICAL DEVICE - A device is provided for connecting a medical apparatus to a network. The device collects data from the medical apparatus and performs a variety of processing functions, such as trending, protocol translation, generating reports, etc. related to the collected data. The device then transmits the collected data over a network to interested parties. In some implementations, the device can transmit the collected data as an email message. | 09-22-2011 |
20120066328 | SYSTEM AND METHOD FOR COMMUNICATING OVER A NETWORK WITH A MEDICAL DEVICE - A medical device is provided that performs a requested action. The requested action may be communicated, for example, to the medical device via email messages. After performing the requested action, a response that is dependent upon the requested action is generated. The generated response is then sent on a network from the medical device as an email message. | 03-15-2012 |
Patent application number | Description | Published |
20080197878 | ENHANCED FIELD PROGRAMMABLE GATE ARRAY - An enhanced performance field programmable gate array integrated circuit comprises a field programmable gate array and other functional circuitry such as a mask-programmable gate array in the same integrated circuit. A circuit interface provides communication between the field programmable gate array, the mask-programmable gate array and the integrated circuit I/O. | 08-21-2008 |
20080204074 | DEDICATED INTERFACE ARCHITECTURE FOR A HYBRID INTEGRATED CIRCUIT - An interface design for a hybrid IC that utilizes dedicated interface tracks to allow signals to interface distributively with the logic blocks of the FPGA portion providing for faster and more efficient communication between the FPGA and ASIC portions of the hybrid IC. | 08-28-2008 |
20100244894 | ENHANCED FIELD PROGRAMMABLE GATE ARRAY - An enhanced performance field programmable gate array integrated circuit comprises a field programmable gate array and other functional circuitry such as a mask-programmable gate array in the same integrated circuit. A circuit interface provides communication between the field programmable gate array, the mask-programmable gate array and the integrated circuit I/O. | 09-30-2010 |
20110234258 | ENHANCED FILED PROGRAMMABLE GATE ARRAY - An enhanced performance field programmable gate array integrated circuit comprises a field programmable gate array and other functional circuitry such as a mask-programmable gate array in the same integrated circuit. A circuit interface provides communication between the field programmable gate array, the mask-programmable gate array and the integrated circuit I/O. | 09-29-2011 |
Patent application number | Description | Published |
20100165528 | UPSTREAM DEVICE OVERVOLTAGE DETECTION WITH DEACTIVATION OF DOWNSTREAM DEVICE POWER - For one disclosed embodiment, a controller comprises communication circuitry to communicate over one or more data lines with a downstream device external to an upstream device having the controller and detection circuitry to detect on at least one of the one or more data lines a voltage having a value in excess of a reference value. The detection circuitry is to deactivate a supply of power over one or more power lines to the downstream device in response to detection on at least one of the one or more data lines of a voltage having a value in excess of the reference value. Other embodiments are also disclosed. | 07-01-2010 |
20140006654 | DEVICE CONNECT DETECTION | 01-02-2014 |
20140006655 | DEVICE DISCONNECT DETECTION | 01-02-2014 |
20140006662 | EXPLICIT CONTROL MESSAGE SIGNALING | 01-02-2014 |
20140006664 | LOW POWER UNIVERSAL SERIAL BUS | 01-02-2014 |
20140006674 | UNIVERSAL SERIAL BUS REPEATER | 01-02-2014 |
20140149609 | DETECTING DEVICE DISCONNECT IN A REPEATER - A method for detecting device disconnect in a repeater is disclosed herein. The method includes receiving a disconnect indication comprising a voltage swing occurring on a data channel for a peripheral device. The method also includes receiving a start-of-frame indication that indicates that a threshold consecutive number of bits of the same data value has been received. The method further includes sending a device disconnect message to a host based on the disconnect indication and the start-of-frame indication. | 05-29-2014 |
20140156876 | DEVICE DISCONNECT DETECTION - Systems and methods for operating a universal serial bus are described herein. The method includes sending packet data from a USB | 06-05-2014 |
20140173166 | REDUCTION OF IDLE POWER IN A COMMUNICATION PORT - Techniques for reducing idle power consumption of a port are described herein. An example method includes determining device presence using a pull-down resistor disposed in a downstream port. The method also includes initiating a low power state of a link between the downstream port and an upstream device. The method also includes disabling the pull-down resistor in response to initiating the low power state. | 06-19-2014 |
Patent application number | Description | Published |
20110111669 | Reconfigurable Clothing Article for a Doll - A doll includes a reconfigurable clothing article coupled thereto. The reconfigurable clothing article can be placed in different configurations relative to the body of the doll. In one configuration, the clothing article can be moved upward and substantially cover an upper portion of the doll body. In another configuration, the clothing article can be moved downward and substantially cover a lower portion of the doll body. In one embodiment, the clothing article may include openings or receiving areas into which the anus of the doll can be inserted. In one embodiment, the clothing article may be placed in intermediate configurations along the body of the doll. | 05-12-2011 |
20120142249 | Toy Figure with Reconfigurable Clothing Article and Output Generating System - A toy doll with a reconfigurable clothing article is disclosed. In particular, a toy doll with a reconfigurable clothing article and an electronic system that generates outputs is disclosed. In one embodiment, the clothing article can be reconfigured relative to the body of the toy doll. In one embodiment, the body of the toy doll includes a display portion that can be used to generate various visual displays. | 06-07-2012 |
20130288564 | Reconfigurable Doll - A doll with reconfigurable hair and dress is disclosed. The hair is rotatably coupled to the top of the head of the doll and a switch within the head of the doll. Furthermore, the switch is connected to the output mechanism, dictating which output the output mechanism produces. When the hair rotates about the head of the doll, the switch is actuated, changing the output of the output mechanism. Additionally, the dress of the doll is capable from converting from a full gown that folds away to reveal a skirt. | 10-31-2013 |
20140273722 | Toy with an Illuminable Movable Portion - A toy doll with an illuminable movable portion is a toy doll with an illumination source, a first portion, and second portion. The second portion is movable with respect to the first portion and includes at least two panels which define housings configured to be illuminated. Each of the housings may include illumination areas, which, upon being aligned with the illumination source may become illuminated. Each of the panels may be selectively aligned with the illumination source. By illuminating different panels of the second portion, the toy doll can be configured in various illumination configurations. A user can influence which panels are illuminated by orienting the toy doll in certain orientations or moving the second portion to different locations with respect to the first portion, among other factors. | 09-18-2014 |
20140329435 | Toy Doll with Movable Portion - A toy doll with a movable portion is a toy doll with a first portion and a second portion that is movably coupled to the first portion and movable between a first configuration and a second configuration. The first portion includes a trigger that may actuate at least one of an engagement assembly and a hinge assembly. The engagement assembly may retain the second portion in the first configuration until the trigger is actuated while the hinge assembly may move the second portion of the toy doll to the second configuration. | 11-06-2014 |
20150072589 | ILLUMINATED DOLL - A lens assembly for a doll with an illuminated torso, including a light-diffusing layer formed from a plurality of co-joined spherical translucent bodies. The assembly may also include a translucent window configured in a shape of a part of the torso, and the light-diffusing layer may be interposed between the translucent window and a light source inside the torso. | 03-12-2015 |
Patent application number | Description | Published |
20090104664 | Use of Molecular chaperones for the enhanced production of secreted, recombinant proteins in mammalian cells - The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein. | 04-23-2009 |
20110144025 | Methods of Reducing Hemorrhage Due to Surgical Procedure - The invention concerns glycosylated proteins having human factor VIII activity. In a preferred embodiment, the protein is glycosylated with oligosaccharides that include an alpha-(2,6)-linked sialic acid and a bisecting GlcNAc linked to a core beta-mannose. | 06-16-2011 |
20120009670 | Use of Molecular Chaperones for the Enhanced Production of Secreted, Recombinant Proteins in Mammalian Cells - The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein. | 01-12-2012 |
20130143818 | Factor VIII Glycoforms - The invention concerns glycosylated proteins having human factor VIII activity. In a preferred embodiment, the protein is glycosylated with oligosaccharides that include an alpha-(2,6)-linked sialic acid and a bisecting GlcNAc linked to a core beta-mannose. | 06-06-2013 |
20130189776 | Use of Molecular Chaperones for the Enhanced Production of Secreted, Recombinant Proteins in Mammalian Cells - The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein. | 07-25-2013 |
20130267468 | FACTOR VIII GLYCOFORMS - The invention concerns glycosylated proteins having human factor VIII activity. In a preferred embodiment, the protein is glycosylated with oligosaccharides that include an alpha-(2,6)-linked sialic acid and a bisecting GlcNAc linked to a core beta-mannose. | 10-10-2013 |
20130330819 | Use of Molecular Chaperones for the Enhanced Production of Secreted, Recombinant Proteins in Mammalian Cells - The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein. | 12-12-2013 |
20130330820 | Use of Molecular Chaperones for the Enhanced Production of Secreted, Recombinant Proteins in Mammalian Cells - The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein. | 12-12-2013 |
20150037841 | Use of Molecular Chaperones for the Enhanced Production of Secreted, Recombinant Proteins in Mammalian Cells - The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein. | 02-05-2015 |
Patent application number | Description | Published |
20090032888 | SEMICONDUCTOR DEVICE - A sidewall spacer structure is formed adjacent to a gate structure whereby a material forming an outer surface of the sidewall spacer structure contains nitrogen. Subsequent to its formation the sidewall spacer structure is annealed to harden the sidewall spacer structure from a subsequent cleaning process. An epitaxial layer is formed subsequent to the cleaning process. | 02-05-2009 |
20130023101 | METHOD AND MANUFACTURE FOR EMBEDDED FLASH TO ACHIEVE HIGH QUALITY SPACERS FOR CORE AND HIGH VOLTAGE DEVICES AND LOW TEMPERATURE SPACERS FOR HIGH PERFORMANCE LOGIC DEVICES - A method and manufacture for memory device fabrication is provided. Spacer formation and junction formation is performed on both: a memory cell region in a core section of a memory device in fabrication, and a high-voltage device region in a periphery section of the memory device in fabrication. The spacer formation and junction formation on both the memory cell region and the high-voltage device region includes performing a rapid thermal anneal. After performing the spacer formation and junction formation on both the memory cell region and the high-voltage device region, spacer formation and junction formation is performed on a low-voltage device region in the periphery section. | 01-24-2013 |
20140209993 | Non-Volatile Memory With Silicided Bit Line Contacts - An approach to use silicided bit line contacts that do not short to the underlying substrate in memory devices. The approach provides for silicide formation in the bit line contact area, using a process that benefits from being self-aligned to the oxide-nitride-oxide (ONO) nitride edges. A farther benefit of the approach is that the bit line contact implant and rapid temperature anneal process can be eliminated. This approach is applicable to embedded flash, integrating high density devices and advanced logic processes. | 07-31-2014 |
20150017795 | Non-Volatile Memory With Silicided Bit Line Contacts - An approach to use silicided bit line contacts that do not short to the underlying substrate in memory devices. The approach provides for silicide formation in the bit line contact area, using a process that benefits from being self-aligned to the oxide-nitride-oxide (ONO) nitride edges. A further benefit of the approach is that the bit line contact implant and rapid temperature anneal process can be eliminated. This approach is applicable to embedded flash, integrating high density devices and advanced logic processes. | 01-15-2015 |
Patent application number | Description | Published |
20080311671 | Mass Spectrometry Method for Measuring Vitamin B6 in Body Fluid - Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5′-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography. | 12-18-2008 |
20090093009 | MASS SPECTROMETRY METHOD FOR MEASURING THIAMINE IN BODY FLUID - Provided are methods for determining the amount of total thiamine in a body fluid sample using liquid chromatography and mass spectrometry. Total thiamine is converted to free thiamine by treatment with an acid phosphatase prior to thiamine separation and quantification. | 04-09-2009 |
20100084545 | Methods for Detecting Vitamin C by Mass Spectrometry - Provided are methods for determining the amount of vitamin C in a sample using mass spectrometry. The methods generally involve ionizing vitamin C in a sample and detecting and quantifying the amount of the ion to determine the amount of vitamin C in the sample. | 04-08-2010 |
20100155592 | VITAMIN B2 DETECTION BY MASS SPECTROMETRY - Methods are described for measuring the amount of a vitamin B2 in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying vitamin B2 in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques. | 06-24-2010 |
20110179855 | METHODS FOR DETECTING VITAMIN C BY MASS SPECTROMETRY - Provided are methods for determining the amount of vitamin C in a sample using mass spectrometry. The methods generally involve ionizing vitamin C in a sample and detecting and quantifying the amount of the ion to determine the amount of vitamin C in the sample. | 07-28-2011 |
20110297825 | MASS SPECTROMETRY METHOD FOR MEASURING VITAMIN B6 IN BODY FLUIDS - Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5′-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography. | 12-08-2011 |
20110306080 | DETERMINATION OF LAMOTRIGINE BY MASS SPECTROMETRY - The present invention relates to compositions and methods for analyzing analytes of interest in liquid samples by mass spectrometry, and preferably in patient samples. Preferred analytes of interest include sirolimus (rapamycin), corticosteroids, bile acids and lamotrigine (lamictal). In one embodiment, by careful selection of target ions, a number of corticosteroids can be analyzed simultaneously and without interference from closely related molecules. In another embodiment, the present methods combine high turbulence liquid chromatography with mass spectrometry performed in positive and negative mode in a single assay to enable the detection and quantification of the composition of bile acid pools. By combining mass spectrometry and high-throughput chromatography, the methods and compositions described herein can provide a rapid, sensitive, and accurate assay for use in large clinical laboratories. | 12-15-2011 |
20120112052 | DETECTION OF VITAMINS A AND E BY TANDEM MASS SPECTROMETRY - Methods are described for measuring the amount of one or more of vitamin A, α-tocopherol, and the combination of β-tocopherol and γ-tocopherol in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying one or more of vitamin A, α-tocopherol, and the combination of β-tocopherol and γ-tocopherol in a sample. | 05-10-2012 |
20130115644 | MASS SPECTROMETRY METHOD FOR MEASURING THIAMINE IN BODY FLUID - Provided are methods for determining the amount of total thiamine in a body fluid sample using liquid chromatography and mass spectrometry. Total thiamine is converted to free thiamine by treatment with an acid phosphatase prior to thiamine separation and quantification. | 05-09-2013 |
20130187039 | VITAMIN B2 DETECTION BY MASS SPECTROMETRY - Methods are described for measuring the amount of a vitamin B2 in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying vitamin B2 in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques. | 07-25-2013 |
20140048703 | METHODS FOR DETECTING VITAMIN C BY MASS SPECTROMETRY - Provided are methods for determining the amount of vitamin C in a sample using mass spectrometry. The methods generally involve ionizing vitamin C in a sample and detecting and quantifying the amount of the ion to determine the amount of vitamin C in the sample. | 02-20-2014 |
20140242711 | VITAMIN B2 DETECTION BY MASS SPECTROMETRY - Methods are described for measuring the amount of a vitamin B2 in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying vitamin B2 in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques. | 08-28-2014 |
20140291502 | METHODS FOR DETECTING VITAMIN C BY MASS SPECTROMETRY - Provided are methods for determining the amount of vitamin C in a sample using mass spectrometry. The methods generally involve ionizing vitamin C in a sample and detecting and quantifying the amount of the ion to determine the amount of vitamin C in the sample. | 10-02-2014 |
20150060659 | VITAMIN B2 DETECTION BY MASS SPECTROMETRY - Methods are described for measuring the amount of a vitamin B2 in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying vitamin B2 in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques. | 03-05-2015 |
Patent application number | Description | Published |
20090215793 | Methods for treating drug resistant cancer - A method for treating drug-resistant cancer, includes: administering to a patient in need thereof, a compound of formula I, a tautomer of the compound, a salt of the compound, a salt of the tautomer, a mixture thereof, or a pharmaceutical composition comprising the compound, the tautomer, the salt of the compound, the salt of the tautomer, or the mixture, wherein the patient is a cancer patient with drug-resistant cancer, wherein the compound of Formula I is as defined in the application. | 08-27-2009 |
20100233187 | GENE PRODUCTS DIFFERENTIALLY EXPRESSED IN CANCEROUS CELLS - The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer. | 09-16-2010 |
20120308569 | GENE PRODUCTS DIFFERENTIALLY EXPRESSED IN CANCEROUS CELLS - The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer. | 12-06-2012 |
20140056912 | METHODS OF TREATING SQUAMOUS CELL CARCINOMA - The disclosure relates to methods for treating a sclerostin-expressing cancer, e.g., a squamous cell carcinoma (SCC), e.g., SCC of the upper aerodigestive tract, esophagus, or lung, employing a therapeutically effective amount of at least one sclerostin antagonist, e.g., an anti-sclerostin antibody, such as Antibody 1, 2, 3, 4 or 5. | 02-27-2014 |
Patent application number | Description | Published |
20090159098 | MATERIAL DELIVERY SYSTEMS AND METHODS - A method of determining one or more operational parameters of a washing system having a wash tank to which water and material are added. In one embodiment, the method includes monitoring a concentration of material, which is decreased at least partially due to water being added to the wash tank. The method also includes maintaining the concentration of material by dispensing material into the wash tank during a material dispensing operation. Additionally, the method includes generating a parameter indicative of a rate at which the material is dispensed during the material dispensing operation. The method also includes determining a presence of a water flow abnormality based at least partially on the generated parameter. | 06-25-2009 |
20100164515 | Method and System for Measuring Water Hardness - Prior to adding detergent or chelant, the conductivity of water in a washing chamber is measured. The maximum concentration of hard water ions that could correspond to the measured conductivity is determined, i.e., it is assumed that all of the conductivity is from calcium and/or magnesium ions in the water even though other ions may in fact be contributing to the measured conductivity. Enough chelating agent is added to the chamber to sequester this maximum concentration of hard water ions and the conductivity is measured again. Using the two conductivity measurements, the actual concentration of hard water ions is determined. A chelant factor based on the actual concentration of hard water ions is then used to determine the amount of chelant to be added for subsequent wash cycles to sequester all of the hard water ions. | 07-01-2010 |
20110253606 | Method and System for Measuring Water Hardness - Prior to adding detergent or chelant, the conductivity of water in a washing chamber is measured. The maximum concentration of hard water ions that could correspond to the measured conductivity is determined, i.e., it is assumed that all of the conductivity is from calcium and/or magnesium ions in the water even though other ions may in fact be contributing to the measured conductivity. Enough chelating agent is added to the chamber to sequester this maximum concentration of hard water ions and the conductivity is measured again. Using the two conductivity measurements, the actual concentration of hard water ions is determined. A chelant factor based on the actual concentration of hard water ions is then used to determine the amount of chelant to be added for subsequent wash cycles to sequester all of the hard water ions. | 10-20-2011 |
20120031433 | MATERIAL DELIVERY SYSTEMS AND METHODS - A method of determining one or more operational parameters of a washing system having a wash tank to which water and material are added. In one embodiment, the method includes monitoring a concentration of material, which is decreased at least partially due to water being added to the wash tank. The method also includes maintaining the concentration of material by dispensing material into the wash tank during a material dispensing operation. Additionally, the method includes generating a parameter indicative of a rate at which the material is dispensed during the material dispensing operation. The method also includes determining a presence of a water flow abnormality based at least partially on the generated parameter. | 02-09-2012 |
Patent application number | Description | Published |
20090003353 | Cross-layer approach to virtualized overlay on ad hoc networks - Methods and apparatus to a cross-layer approach to virtualized overlay on ad hoc networks are described. In one embodiment, a virtual address may be used to search for a (key,value) pair in a virtual overlay. Other embodiments are also described. | 01-01-2009 |
20110211481 | CROSS-LAYER APPROACH TO VIRTUALIZED OVERLAY ON AD HOC NETWORKS - Methods and apparatus to a cross-layer approach to virtualized overlay on ad hoc networks are described. In one embodiment, a virtual address may be used to search for a (key, value) pair in a virtual overlay. Other embodiments are also described. | 09-01-2011 |
20120089663 | APPARATUS FOR END-USER TRANSPARENT UTILIZATION OF COMPUTATIONAL, STORAGE, AND NETWORK CAPACITY OF MOBILE DEVICES, AND ASSOCIATED METHODS - Mobile devices, systems, and methods for end-user transparent utilization of computational, storage, and network capacity of mobile device are described herein. A communication interface may be responsive to a request for a resource from a network of mobile devices. A database may store mobile device information and, in response to the request, identify at least one mobile device having the resource. A virtual machine dispatcher may generate a command to a virtual machine dispatch agent of the at least one mobile device to create a virtual machine to perform the resource. | 04-12-2012 |
Patent application number | Description | Published |
20110087754 | SESSION MANAGER - Methods, apparatuses, and systems for managing signal delivery to a plurality of display platforms are disclosed. A system in accordance with one or more embodiments of the present invention comprises a centralized database, and a plurality of points of presence, each point of presence in the plurality of points of presence coupled to the centralized database, each point of presence comprising a management service and a data cache, wherein the management service maintains a data session with a client based on a comparison of information stored in the data cache and a current client request, the management service further comparing the current client request with the centralized database when the client is denied signal delivery from the system. | 04-14-2011 |
20130053057 | METHOD AND SYSTEM FOR DETERMINING A LOCATION OF A MOBILE DEVICE AND UTILIZING THE LOCATION IN CONTENT SERVICES - A system and method for controlling a mobile device at a headend includes the mobile device communicating a request for content to the headend. The headend requests geographic coordinate location data from the mobile device and, when geographic coordinate data is available, determines a first geographic region associated with the mobile device in response to the geographic coordinate location data. When geographic coordinate data is not available from the mobile device, the headend extracts an IP address from the request and determines a second geographic region based on the IP address and a confidence level. When the confidence level is below a threshold, the headend determines a third geographic region based on subscriber data for the mobile device. The headend controls the mobile device in response to one of the first geographic region, the second geographic region and the third geographic region. | 02-28-2013 |
20140244263 | METHOD AND SYSTEM FOR CONTROLLING A USER RECEIVING DEVICE USING VOICE COMMANDS - A system and method includes a language processing module converting an electrical signal corresponding to an audible signal into a textual signal. The system further includes a command generation module converting the textual signal into a user receiving device control signal. A controller controls a function of a user receiving device in response to the user receiving device control signal. | 08-28-2014 |