Benz, US
Allen Thomas Benz, Boise, ID US
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20100280908 | Method and System for Providing Targeted Advertisements and Messages to a User of an Activity Item List - A method and system that delivers advertisements and messages to a user of an activity item list is described. The method includes associating advertisements and messages with one or more activity items in the activity item list and making the advertisement and messages available to the user at a time of user interest and need. The method includes allowing the user to select an activity item list from a library of pre-defined lists. The user may announce progress on an activity to friends and others on a social network. The method includes allowing businesses and others to obtain the rights to have advertisements and messages associated with activity items. | 11-04-2010 |
August D. Benz, Hillsborough, CA US
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20120204962 | System and Method for Improved Hydrothermal Upgrading of Carbonaceous Material - Methods and apparatus are arranged to increase thermal efficiency, reduce waste water treatment, reduce net usage of fresh water, and improve operational reliability during direct hydrothermal upgrading of carbonaceous materials, including low-rank coals. Drain water collected from the hydrothermal upgrading system is passed through a reboiler system to generate steam which can be returned to the hydrothermal processor system for use therein. | 08-16-2012 |
Bradley Benz, Parker, CO US
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20160097161 | METHOD OF INCREASING PAPER STRENGTH - The invention provides methods and compositions for increasing the strength of a paper sheet. The method involves adding to the paper sheet an amine containing polymer. The amine containing polymer interacts with materials such as GPAM or starch to make the paper stronger in terms including tensile strength, surface strength and bulk strength. | 04-07-2016 |
Bradley J. Benz, Parker, CO US
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20130192782 | METHOD OF USING ALDEHYDE-FUNCTIONALIZED POLYMERS TO INCREASE PAPERMACHINE PERFORMANCE AND ENHANCE SIZING - Disclosed herein are compositions and methods to increase paper machine performance and enhance sizing. The compositions include a sizing agent, an emulsifier, and an aqueous component. The emulsifier may be an aldehyde-functionalized polymer. | 08-01-2013 |
20140336314 | METHOD OF USING ALDEHYDE-FUNCTIONALIZED POLYMERS TO INCREASE PAPERMACHINE PERFORMANCE AND ENHANCE SIZING - Disclosed herein are compositions and methods to increase paper machine performance and enhance sizing. The compositions include a sizing agent, an emulsifier, and an aqueous component. The emulsifier may be an aldehyde-functionalized polymer. The sizing agent may be selected from rosin size, an alkyl ketene dimer, an alkenyl succinic anhydride, and any combination of these sizing agents. | 11-13-2014 |
Bryan J. Benz, Evansville, WI US
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20120261323 | FILTER APPARATUS WITH TORQUE LIMITING MECHANISM - A filter apparatus is described that has a torque limiting device, which may be a clutch mechanism, and which provides a protective function for a filter, so as to protect a filter from being over tightened and to thereby prevent damage to filter components. The clutch mechanism can also eliminate or reduce the need for torque measurement of certain filter components. The clutch mechanism can be located on one of the fluid filter, a filter head which engages the fluid filter, or a combination of both the fluid filter and the filter head. | 10-18-2012 |
Charles Joseph Benz, Santa Cruz, CA US
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20160070855 | Systems And Methods For Determination Of Provenance - Systems and methods for genomic analysis are contemplated in which idiosyncratic markers or marker constellations are employed to characterize and compare genomic sequences. In especially preferred aspects, the idiosyncratic markers are predetermined SNPs and a marker profile is used in a sample record to so allow cross reference to other marker profiles of other sequences. | 03-10-2016 |
Christopher Benz, Novato, CA US
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20110130296 | MULTI-GENE CLASSIFIERS AND PROGNOSTIC INDICATORS FOR CANCERS - The present invention relates to the identification of marker genes useful in the diagnosis and prognosis of clinically problematic subsets of primary breast cancers. More specifically, the invention relates to the identification of two sets of marker genes that are differentially expressed in and useful for the diagnosis and prognosis of subsets of hormone receptor-negative (HRneg; i.e., ER and PR negative) and triple-negative (Tneg; i.e., ER, PR and HER2 negative) primary breast cancers at highest risk for early metastatic relapse. The invention further provides methods for determining the best course of treatment for patients having one of these clinically problematic subsets of primary breast cancers. The invention also provides methods for identifying compounds that prevent or treat a subtype of breast cancer based on their ability to modulate the activity or expression level of one or more marker genes identified herein. | 06-02-2011 |
Christopher C. Benz, Novato, CA US
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20100068255 | Immunoliposomes that Optimize Internationalization into Target Cells - The present invention provides for immunoliposomes that optimizes internalization of a drug into target cells bearing a characteristic cell surface marker. The immunoliposomes comprise an Fab′ domain of an antibody that specifically binds the characteristic marker, an amphipathic vesicle-forming lipid, and a polyethylene glycol derivatized lipid. The invention also provides for growth-inhibiting immunoliposomes that lack growth-inhibiting therapeutic agents and yet are capable of inhibiting the growth and proliferation of target cells. | 03-18-2010 |
20120264159 | SCREENING SYSTEM FOR MODULATORS OF HER2 MEDIATED TRANSCRIPTION AND HER2 MODULATORS IDENTIFED THEREBY - This invention pertains to the development of a screening system to identify (screen for) HER2 promoter silencing agents. Such agents are expected to be of therapeutic value in the treatment of cancers characterized by HER2 amplification/upregulation. In addition, this invention pertains to the discovery that histone deacetylase (HDAC) inhibitors like sodium butyrate and trichostatin A (TSA), in a time and dose dependent fashion can silence genomically integrated and/or amplified/overexpressing promoters, such as that driving the HER2/ErbB2/neu oncogene, resulting in inhibition of gene products including transcripts and protein, and subsequent production of tumor/cell growth inhibition, apoptosis and/or differentiation. In another embodiment, this invention provides novel SNPs associated with the coding region of the ERbB2 proto-oncogene. The SNPs are indicators for altered risk, for developing ErbB2-positive cancer in a mammal. | 10-18-2012 |
20150359794 | IMPAIRMENT OF THE LARGE RIBOSOMAL SUBUNIT PROTEIN RPL24 BY DEPLETION OR ACETYLATION - Provided herein are compositions of histone deacetylase (HDAC) inhibitors for the treatment of cancers overexpressing the large ribosomal subunit protein 24 (RPL24) in a subject in need thereof. Provided herein are methods for treating RPL24-overexpressing cancers in a subject in need thereof, comprising administering to the subject an effective amount of an HDAC inhibitor. Also provided herein are methods for inhibiting the viability of an RPL24-overexpressing cancer cell with an HDAC inhibitor. Also provided herein are methods for assessing the efficacy of an HDAC inhibitor against a cancer. | 12-17-2015 |
Erek Benz, Park Ridge, IL US
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20110167676 | Footwear with Enhanced Cleats - A shoe includes a sole having a plurality of cleats thereon at spaced apart locations. The cleats are configured to enhance the performance of the shoe based upon the specific characteristics of movement of the user. The cleats may include differently configured first and second cleats. Each first cleat includes at least one first directional pattern and each second cleat includes at least one second directional pattern. Individual cleats and methods of assembling and designing a shoe are also provided. | 07-14-2011 |
Erek T. Benz, Park Ridge, IL US
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20100050475 | FOOTWEAR SOLE STRUCTURE - A shoe structure for athletic use includes an upper adapted and constructed to at least partially cover an upper surface of the foot of a wearer of the shoe. A sole element is secured to the upper, and is fabricated from a relatively flexible and cushioned material. A plurality of multi-island platforms are secured to the sole element. The multi-island platforms have varying degrees of stiffness. Stiffer multi-island platforms are located in areas of the foot requiring stiffness to enhance footwear performance, and more flexible multi-island platforms are located in areas of the foot requiring flexibility to enhance footwear performance. | 03-04-2010 |
Eric Benz, Nashville, NC US
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20150337927 | SPACER FOR BELT TENSIONER - A belt assembly for internal combustion engine that has a tensioner mount is described. The belt assembly includes a spacer that is rotatably coupleable to the tensioner mount, and a tensioner that is co-rotatably coupled to the spacer. The spacer is positioned between the tensioner and the tension mount. | 11-26-2015 |
Eric Benz, Peoria, IL US
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20090013517 | Repair and resurfacing methods for use in remanufacturing a machine system - A method of repairing a housing for a machine system includes returning an inner diameter of at least one bearing bore of the housing to a uniform diameter state. The at least one bearing bore is prepared for resurfacing via removing deeply entrapped grease from within pores in cast surface material of the housing subsequent to returning the inner diameter to a uniform diameter state. Subsequent to preparing the at least one bearing bore for resurfacing, it is resurfaced with a material different from cast material of the housing and bonded therewith, for example via thermal spray coating. Resurfacing a cast metallic component, of iron, steel, or the like with metal spray coating may include removing deeply embedded grease from pores of cast surface material of a cast component, in preparation for spraying the cast component with metal spray resurfacing material. | 01-15-2009 |
Eric W. Benz, Peoria, IL US
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20080302705 | Process for determining whether used friction elements may be returned to service - A sorting process for used friction elements such as friction discs is provided, including determining whether the friction elements are heat compromised based at least in part on a wave scattering property of at least one frictionally interactive face of each of the used friction elements. Suitable friction elements may be sorted into an acceptable category, and unsuitable friction elements sorted into a scrap category. A method of assembling a machine system such as a transmission includes determining suitability of a friction element for service therein by measuring a wave scattering property such as reflectivity of at least one frictionally interactive face of the friction element, and coupling the friction element with the same or a different machine system for returning to service therein based at least in part on the determination of suitability. | 12-11-2008 |
20100187163 | PROCESS FOR DETERMINING WHETHER USED FRICTION ELEMENTS MAY BE RETURNED TO SERVICE - A sorting process for used friction elements such as friction discs is provided, including determining whether the friction elements are heat compromised based at least in part on a wave scattering property of at least one frictionally interactive face of each of the used friction elements. Suitable friction elements may be sorted into an acceptable category, and unsuitable friction elements sorted into a scrap category. A method of assembling a machine system such as a transmission includes determining suitability of a friction element for service therein by measuring a wave scattering property such as reflectivity of at least one frictionally interactive face of the friction element, and coupling the friction element with the same or a different machine system for returning to service therein based at least in part on the determination of suitability. | 07-29-2010 |
Frank-Michael Benz, Novi, MI US
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20100058847 | METHOD OF ENGINE OIL CONSUMPTION - The disclosure is directed to a method to determine oil consumption in an internal combustion engine that does not require extended operation of the engine in the files and is adaptable to be useful at production facilities for testing of sample engines from the line without installation of the engine into a vehicle and operating the vehicle in order to determine oil consumption of the engine during operating conditions. | 03-11-2010 |
Gary Benz, Brentwood, TN US
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20130318711 | STADIUM BLANKET WITH ACCESSORIES KIT - An improved stadium blanket is described with having storage capacity for storing accessories, some of which may be provided with the stadium blanket, brought to events. | 12-05-2013 |
Gregory H. Benz, Saline, MI US
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20080221827 | SYSTEM FOR VALIDATING VELOCITIES OF COMPONENTS IN A VEHICLE - A system for validating velocities of components in a vehicle uses sensor measurements and mathematical relationships between the vehicle components to validate the velocities. A controller or controllers receive speed or velocity inputs and mathematically combine the velocities of more than one of the vehicle components. The velocities of at least one of the vehicle components is validated when the mathematical combination meets at least one predetermined criterion. The validated velocity or velocities are then communicated to at least one of the vehicle components. | 09-11-2008 |
Jeffrey A. Benz, Middletown, OH US
Patent application number | Description | Published |
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20120243878 | RADIO FREQUENCY AND DIGITAL SIGNAL DUAL CARRIER MULITPLE MODULATION SYSTEM - The present invention is a radio frequency and digital signal dual carrier multiple modulation system that includes a transmitter system with digital components that include digital inputs, carrier signal sources, a multiplexer and logic controlled radio frequency switches that produces modulated signals and radio frequency components that includes radio frequency signal input and a radio frequency variable gain amplifier. There is also a receiver system with digital components that include a demultiplexer, buffer amplifiers, detectors, comparators and digital signal outputs that receive modulated signals from the transmitter system and radio frequency components with another radio frequency variable gain amplifier that receives the radio frequency output from the transmitter system and produces an amplified radio frequency output. | 09-27-2012 |
Jennifer Bantrell Benz, Rockville, MD US
Patent application number | Description | Published |
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20100280908 | Method and System for Providing Targeted Advertisements and Messages to a User of an Activity Item List - A method and system that delivers advertisements and messages to a user of an activity item list is described. The method includes associating advertisements and messages with one or more activity items in the activity item list and making the advertisement and messages available to the user at a time of user interest and need. The method includes allowing the user to select an activity item list from a library of pre-defined lists. The user may announce progress on an activity to friends and others on a social network. The method includes allowing businesses and others to obtain the rights to have advertisements and messages associated with activity items. | 11-04-2010 |
John G. Benz, Glendale, MO US
Patent application number | Description | Published |
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20140144092 | SYSTEM AND APPARATUS FOR INSTALLATION OF TILE FLOOR - A tile floor system and apparatus, and manner of installation, uses ceramic and other rigid tiles, and a rubbery or polymeric mat or array of mats, providing a grid or pattern of receptacles that cooperatively receive and securely hold the tiles, with a removable grout securable between the tiles, so as to present a convincing appearance of a conventionally mortared and grouted tile floor, with the tiles and grout concealing the mats. The system and apparatus can be configured so as to be quickly and easily removed or replaced, Each mat can be configured for receiving one or multiple tiles, and the adjacent mats are joined together in the pattern or grid using suitable connectors, such as disk shaped biscuits receivable in slots along opposing sides of the individual mats. | 05-29-2014 |
Marcel Benz, Cambridge, MA US
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20100126284 | METHOD, APPARATUS, AND SYSTEM FOR INTEGRATED VAPOR AND PARTICULATE SAMPLING - A detection system for identifying an unknown substance includes a detector assembly configured to receive a particulate or vapor and determine a substance contained within the collected vapor or particulate sample, and at least one heater element operatively coupled in flow communication with the detector assembly. The heater element is configured to attract an airborne vapor when the detection system is in a vapor mode, and desorb at least a portion of the attracted particulate when the detection system is in a particulate mode. | 05-27-2010 |
Marcel Benz, San Diego, CA US
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20120270205 | HIGH-FLUX CHEMICAL SENSORS - The present invention relates to the field of chemical detection. Specifically, the invention provides devices that respond quickly to various target chemical analytes present in the environment. Responses are based on a change in an electrical property (such as impedance or resistance) caused by adsorption or absorption of the target analyte(s) to or in a substrate-free chemical sensing element. The chemical sensing element is composed of a thin, electrically conductive polymer material (due to doping of structural polymer material(s) with electrically conductive particles and/or the use of electrically conductive polymer material(s)), which can allow vapors to pass through with little pressure drop. The chemical sensing material is either suspended in the environment, or emplaced adjacent to one or between two porous membranes, resulting in a sensing patch capable of high gas or vapor flux through the chemical sensing element. | 10-25-2012 |
20140220703 | HIGH-FLUX CHEMICAL SENSORS - The present invention relates to the field of chemical detection. Specifically, the invention provides devices that respond quickly to various target chemical analytes present in the environment. Responses are based on a change in an electrical property (such as impedance or resistance) caused by adsorption or absorption of the target analyte(s) to or in a substrate-free chemical sensing element. The chemical sensing element is composed of a thin, electrically conductive polymer material (due to doping of structural polymer material(s) with electrically conductive particles and/or the use of electrically conductive polymer material(s)), which can allow vapors to pass through with little pressure drop. The chemical sensing material is either suspended in the environment, or emplaced adjacent to one or between two porous membranes, resulting in a sensing patch capable of high gas or vapor flux through the chemical sensing element. | 08-07-2014 |
Michael Benz, Ramsey, MN US
Patent application number | Description | Published |
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20110202000 | ANTI-AMYLOID BETA ANTIBODIES CONJUGATED TO SIALIC ACID-CONTAINING MOLECULES - Antibody complexes including anti-Aβ antibodies conjugated with a sialic acid-containing molecule show improved bioavailability with no significant adverse effects on binding to amyloid beta. | 08-18-2011 |
20110251545 | Cell Reservoirs Created by Polymer Plugs - Described herein generally are catheter systems used to deliver cells and other bioactive materials to a target location within the vascular system of the human body, and methods of delivering cells and other bioactive materials to such target locations. | 10-13-2011 |
Michael E. Benz, Ramsey, MN US
Patent application number | Description | Published |
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20090202436 | Bupivacaine Formulation in a Polyorthoester Carrier - Effective treatments of pain, such as chronic pelvic pain, for extended periods of time are provided. The treatments include the administration of one or more drug depots intraspinally wherein the drug depots include an effective amount of bupivacaine formulated within a polyorthoester. By administration of one or more drug depots, one can relieve pain caused by diverse sources, including but not limited to chronic pelvic pain syndromes, spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. In some embodiments, the relief can be for at least thirty days, at least sixty days, at least one hundred days or at least one hundred and thirty-five days. | 08-13-2009 |
20090202604 | Benzodiazepine Formulation in a Polyorthoester Carrier - Effective treatments of pain for extended periods of time are provided. The treatments include the administration of one or more drug depots intraspinally wherein the drug depots include an effective amount of a benzodiazepine, such as midazolam, formulated within a polyorthoester. By administration of one or more drug depots, one can relieve pain caused by diverse sources, including but not limited to chronic pelvic pain syndromes, spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. In some embodiments, the relief can be for at least twenty-five days, at least fifty days, at least one hundred days or at least one hundred and thirty-five days. | 08-13-2009 |
20090208554 | Baclofen Formulation in a Polyorthoester Carrier - Effective treatments of pain for extended periods of time are provided. The treatments include the administration of one or more drug depots intraspinally wherein the drug depots include an effective amount of baclofen formulated within a polyorthoester. By administration of one or more drug depots, one can relieve pain caused by diverse sources, including but not limited to chronic pelvic pain syndromes, spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. In some embodiments, the relief can be for at least thirty days, at least sixty days, at least one hundred days or at least one hundred and thirty-five days. | 08-20-2009 |
20100311935 | MOISTURE CURABLE MATERIALS FOR DELIVERY OF AGENTS, METHODS, AND MEDICAL DEVICES - The present invention provides curable materials, medical devices incorporating such materials, wherein the curable materials are capable of releasing hydrolyzable leaving agents upon hydrolysis that can form agents (e.g., pharmaceutically active agents), and methods of making and using such materials and devices. | 12-09-2010 |
Oscar S. Benz, Minneapolis, MN US
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20080220264 | FLUOROCHEMICAL COMPOUNDS HAVING PENDENT SILYL GROUPS - Fluorochemical silane compounds and coating compositions derived therefrom are described. The compounds and compositions may be used in treating substrates, in particular substrates having a hard surface such as ceramics or glass, to render them water, oil, stain, and soil repellent. | 09-11-2008 |
20090025727 | RESPIRATOR, WELDING HELMET, OR FACE SHIELD THAT HAS LOW SURFACE ENERGY HARD-COAT LENS - A personal safety protective device that includes a lens and a support structure onto which the lens is secured. The lens includes a substrate and a hard-coat layer located on the substrate of the lens. The hard-coat layer has a low surface energy outer surface that is derived from a) an additive that includes at least one of i) a perfluoropolyether urethane that includes hydrolysable silane groups, and ii) an acrylate polymer that includes at least one perfluoropolyether moiety and at least one hydrolysable silane group, and b) a silsesquioxane-based hard-coat composition. The provision of such a lens on a personal safety protective device enables the lens to be durable to abrasion and to be easily cleaned without use of solvents that could shorten the service life of the lens. | 01-29-2009 |
Oscar S. Benz, Pittsburgh, PA US
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20100105828 | FLUOROCHEMICAL URETHANE COMPOUNDS HAVING PENDENT SILYL GROUPS - Fluorochemical urethane compounds and coating compositions derived therefrom are described. The compounds and compositions may be used in treating substrates, in particular substrates having a hard surface such as ceramics or glass, to render them water, oil, stain, and soil repellent. | 04-29-2010 |
Patrick H. Benz, Sarasota, FL US
Patent application number | Description | Published |
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20080221235 | POLYMERS FOR INTRAOCULAR LENSES - The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer. | 09-11-2008 |
20080242818 | LIGHT FILTERS COMPRISING A NATURALLY OCCURRING CHROMOPHORE AND DERIVATIVES THEREOF - A composition comprising a polymer backbone and at least one side group, wherein the side group comprises a benzene ring-based chromophore comprising a ketone at the 1-position, a substituted or unsubstituted amino group at the 2-position, and an oxygen atom at the 3-position of the benzene ring. The chromophore is a kynurenine-based compound. Methods of making and using the composition are also provided. The composition can be used in an ophthalmic lens or device for protecting the retina by blocking UV rays and filtering violet rays. | 10-02-2008 |
20090176909 | HYDROGEL WITH HIGH WATER CONTENT AND STABILITY - A polymer comprising hydrophilic and hydrophobic properties is provided. The polymer can be formed into a hydrogel capable of being used as a contact lens. The lens can exhibit high water content such as for example more than 70 wt. % for biocompatibility and structural stability for handling. The hydrophilic portion can be 2,3-dihydroxypropyl methacrylate (GMA) and the hydrophobic portion can be 2-methoxyethyl methacrylate (MOEMA). Additionally, the lens can also include N,N-dimethylacrylamide (NN-DMA). Lens can be prepared and formed by molding including a cast molding process or a half cast molding process. | 07-09-2009 |
20110043829 | SURFACE ALIGNMENT AND POSITIONING METHOD AND APPARATUS - A method and apparatus for aligning and positioning a surface such that the optical and/or cylinder axis of the surface is precisely aligned with a fixture for the purpose of assembly or further mechanical operations such as machining and polishing. According to another aspect of the invention, a lens apex is located and precisely positioned a constant distance from a reference point. In order to implement the above, a method and apparatus is disclosed for optically aligning and positioning surfaces using a precision laser displacement measurement device, an X-Y-Z micron stage, and a microprocessor (or computer) capable of performing curvature analysis. | 02-24-2011 |
20110166381 | LIGHT FILTERS COMPRISING A NATURALLY OCCURRING CHROMOPHORE AND DERIVATIVES THEREOF - A composition comprising a polymer backbone and at least one side group, wherein the side group comprises a benzene ring-based chromophore comprising a ketone at the 1-position, a substituted or unsubstituted amino group at the 2-position, and an oxygen atom at the 3-position of the benzene ring. The chromophore is a kynurenine-based compound. Methods of making and using the composition are also provided. The composition can be used in an ophthalmic lens or device for protecting the retina by blocking UV rays and filtering violet rays. | 07-07-2011 |
20110264211 | MATERIALS FOR MAKING HYDROPHOBIC INTRAOCULAR LENS - The present invention provides copolymers made up of alkoxyalkyl methacrylate and/or alkoxyalkyl acrylate monomers in combination with one or more additional hydrophobic monomers. The copolymers may be used in the manufacture of intraocular lenses, including both the optic and haptic portions of the lenses. The present invention also provide methods for making intraocular lenses from the copolymers. | 10-27-2011 |
20120190767 | HYDROGEL WITH HIGH WATER CONTACT AND STABILITY - A polymer comprising hydrophilic and hydrophobic properties is provided. The polymer can be formed into a hydrogel capable of being used as a contact lens. The lens can exhibit high water content such as for example more than 70 wt. % for biocompatibility and structural stability for handling. The hydrophilic portion can be 2,3-dihydroxypropyl methacrylate (GMA) and the hydrophobic portion can be 2-methoxyethyl methacrylate (MOEMA). Additionally, the lens can also include N,N-dimethylacrylamide (NN-DMA). Lens can be prepared and formed by molding including a cast molding process or a half cast molding process. | 07-26-2012 |
20130107203 | METHOD FOR DETERMINING THE OPTIC CENTER OF A LENS BLANK | 05-02-2013 |
20130178555 | POLYMERS FOR INTRAOCULAR LENSES - The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer. | 07-11-2013 |
20130253159 | HYDROPHOBIC INTRAOCULAR LENS - An intraocular lens (IOL) with excellent non-glistening characteristics comprising at least one copolymer comprising: (a) one or more first monomeric subunits comprising a polymerized acrylate and/or methacrylate group, at least one side group comprising (i) an aryloxy moiety, and (ii) an aliphatic carbon moiety linking the aryloxy moiety with the polymerized acrylate or methacrylate group, wherein the aliphatic carbon moiety comprises at least one hydroxyl substituent, (b) one or more second monomeric subunits different from the first monomeric subunits comprising a polymerized acrylate and/or methacrylate group, and comprising at least one alkoxyalkyl side group, (c) one or more third monomeric subunits different from the first and second monomeric subunits, the third monomeric subunits comprising a polymerized acrylate and/or methacrylate group, and comprising at least one alkylene oxide side group, wherein the first monomeric subunit is present in a greater amount by weight than the second monomeric subunit, and the first and second monomeric subunits together comprise about 75 percent or more of the monomeric subunits composition by weight. | 09-26-2013 |
20140264981 | PROCESS FOR MANUFACTURING AN INTRAOCULAR LENS WITH AN EMBEDDED MASK - Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a mask adapted to increase depth of focus. The method of manufacturing the implant can include positioning the mask with an aperture on a protruding pin of a positioning mold portion. The protruding pin can be configured to center the mask in the intraocular lens. | 09-18-2014 |
20150061168 | POLYMERS FOR INTRAOCULAR LENSES - The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer. | 03-05-2015 |
20150073549 | INTRAOCULAR LENS WITH ELASTIC MASK - Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a lens body having a lens material and a mask having a mask material. The lens body can be secured to the mask. The mask material can include a modulus of elasticity that is greater than or equal to a modulus of elasticity of the lens material. | 03-12-2015 |
20160101579 | MANDREL FOR HOLDING AN INTRAOCULAR LENS BLANK AND METHOD OF MAKING AN INTRAOCULAR LENS USING THE SAME - A mandrel ( | 04-14-2016 |
Patrick H. Benz, Saratosa, FL US
Patent application number | Description | Published |
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20130096273 | ULTRAVIOLET LIGHT ABSORBING MATERIALS FOR INTRAOCULAR LENS AND USES THEREOF - A method for reducing the transmittance of ultraviolet radiation through an intraocular lens to 10% or less at 370 mm Additionally, a method for preventing the transmittance of at least 90% of ultraviolet radiation at 370 nm through a foldable intraocular lens comprising: (a) incorporating a monomer comprising a 4-(4,6-diphenyl-1,3,5-triazin-2-yl)-3-hydroxyphenoxy moiety into at least one polymer and (b) forming the polymer into a material suitable for use as an intraocular lens, wherein the monomer comprising a 4-(4,6-diphenyl-1,3,5-triazin-2-yl)-3-hydroxyphenoxy moiety comprises 0.10 to 0.15 weight percent of the overall dry polymer. | 04-18-2013 |
Phil Benz, Denver, CO US
Patent application number | Description | Published |
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20090089070 | System and Method for Validating and Processing Customer Entered Addresses - A system includes an address validation and resolution module operable to determine a location corresponding to a civic address; a location key generator operable to generate a location key adapted to index a set of location-based services identifiers; and an available services determination module operable to use the location key to index the set of location-based services identifiers to determine location-based services available at the civic address. An embodiment of a computer-implemented method includes receiving address data identifying a civic address associated with a, determining a location corresponding to the identified civic address based on the address data; and determining whether one or more services are available at the identified civic address based on the determined location. | 04-02-2009 |
Philip Benz, Portland, OR US
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20090149764 | Circulation monitoring system and method - A lightweight portable probe or transducer containing a transmissive or reflective electro-optical emitter and receptor in the infrared spectrum is fitted on a subject's finger or toe. Associated electronics energize and monitor the probe, detect cardio-rhythmic fluctuations therefrom, and process digital data over a prescribed window to produce a non-invasive, qualitative or quantitative measure of the subject's circulation. In accordance with one embodiment of the invention, a simple tri-color LED array is used to indicate the subject's circulation as being normal, reduced, or borderline. | 06-11-2009 |
20150018869 | Apparatus and Method of Use for an Adjustable Radial and Ulnar Compression Wristband - An adjustable radial and ulnar vascular compression wristband assists in achieving partial or full occlusion of a blood vessel when applied to a patient's wrist during or following a medical procedure. At least two adjustably inflatable non-adjacent balloons on the wristband apply preferential compression to portions of the circumference of the wrist, including in particular those portions overlying the ulnar and radial arteries. | 01-15-2015 |
20150101619 | Integrated Armboard and Wrist Support Apparatuses and Methods of Use - The present invention includes an apparatus, to be used during a medical procedure to support a patient's arm, which generally includes an armboard and an optional wrist support device attached to a patient that may be removably connected to the armboard, and a general method of use. | 04-16-2015 |
20150272592 | Adjustable Ratcheting Vascular Compression Device and Method of Use - A ratcheting adjustable vascular compression device assists in achieving partial or full occlusion of a blood vessel when applied to a patient's limb, during or following a medical procedure. During deployment, a compression pad on the device applies preferential compression to at least one portion of the circumference of the limb. Further, securement, adjustment and rapid release of the device are all enabled by an alternate ratcheting mechanism that enables gradual adjustments to be made to the tightness and thus to the compression applied without releasing the device, so as to permit patent blood flow through blood vessels in the limb during the compression period. | 10-01-2015 |
20160101269 | Apparatus For A Medical System Inflation Syringe - The medical system inflation syringe of the present invention enables a fluid communication selective interconnection of a male connector with a subset of certain female connectors, while preventing interconnection of said male connector with other subsets of female connectors, for the purpose of providing secure interconnection to achieve fluid (including gas or air) communication only with medical systems with which the inflation syringe is intended to be interconnected. | 04-14-2016 |
Robert Benz, Modesto, CA US
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20160040559 | Cogeneration with nucleate boiling cooled internal combustion engine - A cogeneration system for generating electricity and process steam. The system includes an internal combustion engine having a shaft and a cooling system comprising a cooling fluid adapted to circulate through the engine and to cool the engine under conditions of nucleate boiling in which at least 10 percent of the coolant exits the engine in a vapor phase. It includes a vapor separator adapted to separate the coolant that exits the engine into a vapor phase coolant and a liquid phase coolant. The engine shaft drives an electric generator to provide electric power. A hot vapor line directs hot vapor exiting the vapor separator to a hot vapor process load. A coolant circulation pump is provided to force the cooling fluid through the engine, and a hot water line is provided to return hot water exiting the vapor separator to the coolant circulation pump. In preferred embodiments the system further includes an excess steam condenser for to collecting and condensing excess steam not needed by the hot vapor load, a condensate return tank adapted to store condensate from the hot vapor load and the excess steam condenser, and a condensate return line adapted to return condensate to the coolant recirculation pump. | 02-11-2016 |
Robert P. Benz, Hermosa Beach, CA US
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20120234264 | COGENERATION POWER PLANT - A cogeneration power plant for producing steam and electricity. A boiler burner receives fuel from a fuel source and a boiler combustion air/exhaust mixture from a boiler combustion air fan. Combustion occurs inside the burner and hot gases are generated which are used to provide heat for the boiler. An internal combustion engine receives fuel and air for combustion. The internal combustion engine drives an electricity generator for the production of electricity. An engine jacket and oil cooler are utilized to provide cooling for the engine. A water circuit is configured to remove heat from the engine jacket and oil cooler. The heated water flows through a water-to-air heat exchanger connected to the water circuit. The water-to-air heat exchanger utilizes the heated water to heat ambient air through the heat exchanger to produce heated boiler combustion air. Engine exhaust from the internal combustion engine combines with the preheated boiler combustion air in a boiler combustion air fan for producing a boiler combustion air/exhaust mixture for the burner. A boiler exhaust duct directs boiler exhaust away from the boiler. A boiler combustion control system automatically monitors the boiler load and the combustion air and engine exhaust mixture oxygen level and temperature. The boiler combustion control system will then appropriately automatically adjust the speed of the boiler combustion air fan to provide a near stoichiometric mixture of fuel and combustion air and engine exhaust mixture so as to provide for a high burner temperature causing the reduction of NO | 09-20-2012 |
Ryan Benz, Huntington Beach, CA US
Patent application number | Description | Published |
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20140234854 | METHOD FOR EVALUATION OF PRESENCE OF OR RISK OF COLON TUMORS - The disclosed methods are used to predict or assess colon tumor status in a patient. They can be used to determine nature of tumor, recurrence, or patient response to treatments. Some embodiments of the methods include generating a report for clinical management. The methodology provided herein is intended to detect technical variations and to allow for data normalization and enhance signal detection and build predictive proteins profiles of disease status and response. | 08-21-2014 |
20150111220 | METHOD FOR EVALUATION OF PRESENCE OF OR RISK OF COLON TUMORS - The disclosed methods are used to predict or assess colon tumor status in a patient. They can be used to determine nature of tumor, recurrence, or patient response to treatments. Some embodiments of the methods include generating a report for clinical management. The methodology provided herein is intended to detect technical variations and to allow for data normalization and enhance signal detection and build predictive proteins profiles of disease status and response. | 04-23-2015 |
20150111221 | METHOD FOR EVALUATION OF PRESENCE OF OR RISK OF COLON TUMORS - The disclosed methods are used to predict or assess colon tumor status in a patient. They can be used to determine nature of tumor, recurrence, or patient response to treatments. Some embodiments of the methods include generating a report for clinical management. The methodology provided herein is intended to detect technical variations and to allow for data normalization and enhance signal detection and build predictive proteins profiles of disease status and response. | 04-23-2015 |
20150111223 | METHOD FOR EVALUATION OF PRESENCE OF OR RISK OF COLON TUMORS - The disclosed methods are used to predict or assess colon tumor status in a patient. They can be used to determine nature of tumor, recurrence, or patient response to treatments. Some embodiments of the methods include generating a report for clinical management. The methodology provided herein is intended to detect technical variations and to allow for data normalization and enhance signal detection and build predictive proteins profiles of disease status and response. | 04-23-2015 |
20150111230 | METHOD FOR EVALUATION OF PRESENCE OF OR RISK OF COLON TUMORS - The disclosed methods are used to predict or assess colon tumor status in a patient. They can be used to determine nature of tumor, recurrence, or patient response to treatments. Some embodiments of the methods include generating a report for clinical management. The methodology provided herein is intended to detect technical variations and to allow for data normalization and enhance signal detection and build predictive proteins profiles of disease status and response. | 04-23-2015 |
Stephen C. Benz, Santa Cruz, CA US
Patent application number | Description | Published |
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20120041683 | Pathway recognition algorithm using data integration on genomic models (PARADIGM) - The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy. | 02-16-2012 |
20120158391 | Pathway recognition algorithm using data integration on genomic models (PAGADIGM) - A patient sample specific dynamic pathway map is constructed on the basis of measured patient data and a probabilistic pathway model that is based on attributes for pathway elements, wherein some attributes for pathway elements are known a priori, where other attributes for the pathway elements are assumed, and where the pathway elements are cross-correlated and assigned an influence level for at least one pathway. Preferred dynamic pathway maps provide context of the measured patient data with respect to a selected reference pathway activity. | 06-21-2012 |
20150142465 | PATHWAY RECOGNITION ALGORITHM USING DATA INTEGRATION ON GENOMIC MODELS (PARADIGM) - A patient sample specific dynamic pathway map is constructed on the basis of measured patient data and a probabilistic pathway model that is based on attributes for pathway elements, wherein some attributes for pathway elements are known a priori, where other attributes for the pathway elements are assumed, and where the pathway elements are cross-correlated and assigned an influence level for at least one pathway. Preferred dynamic pathway maps provide context of the measured patient data with respect to a selected reference pathway activity. | 05-21-2015 |
Stephen Charles Benz, Santa Cruz, CA US
Patent application number | Description | Published |
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20140249847 | Healthcare Object Recognition Systems And Methods - Healthcare object (HCO) discriminator systems and methods are presented. Systems can obtain a digital representation of a scene via a sensor interface. An HCO discriminator platform analyzes the digital representation to discriminate objects within the scene as being associated with a type of HCO or as being unrelated to a type of HCO. Once the HCO recognition platform determines that a type of HCO is relevant, it instantiates an actual HCO. The HCO can be routed to one or more destinations based on routing rules generated from a template or based on the manner in which the objects in the scene were discriminated. | 09-04-2014 |
20140350130 | MDM2-Containing Double Minute Chromosomes And Methods Therefore - Contemplated systems and methods allow for computational genomic analysis using paired-end sequence analysis and split read refinement to thereby identify high-confidence breakpoints associated with high copy numbers and orientation of rearrangements, which is then the basis for full reconstruction of double minutes (DM). In especially preferred aspects, the DM will also include an oncogene or tumor suppressor gene, and/or may be found in blood or blood derived fluids. | 11-27-2014 |
20140368550 | Distributed System Providing Dynamic Indexing And Visualization Of Genomic Data - Systems and methods for dynamic visualization of genomic data are provided in which a genomic visualization system adapts presentation of information content according to scale-relevant annotations within a sequence object. | 12-18-2014 |
20150088432 | SYSTEMS, METHODS, AND COMPOSITIONS FOR VIRAL-ASSOCIATED TUMORS - Contemplated systems and methods employ chimeric reference sequences that include a plurality of viral genome sequences to identify/quantify integration and co-amplification events. Most typically, the viral genome sequences are organized in the chimeric reference sequences as single chromosomes and the chimeric reference sequences are in BAM format. | 03-26-2015 |
20150134662 | Systems And Methods For Transmission And Pre-Processing Of Sequencing Data - “Omic” digital data transport systems and methods are disclosed. The disclosed systems and methods employ a transport server that assembles a transport group larger numbers of omic output files on the basis of machine specific annotation from one or more sequencing devices and user input related to one or more attributes for the omic output files. | 05-14-2015 |
20150262082 | Systems And Methods For Learning And Identification Of Regulatory Interactions In Biological Pathways - Contemplated systems and methods provide for machine learning and identification of regulatory interactions in biological pathways using a probabilistic graphical model, and especially for identification of interaction correlations among the regulatory parameters. | 09-17-2015 |
20150310228 | SECURED MOBILE GENOME BROWSING DEVICES AND METHODS THEREFOR - A secured mobile genome browsing device is disclosed. The device can store genome data in a webapp format within an isolated, secured container in memory. The device further comprises a genome browser module that identifies relevant genome data and renders the relevant genome data, including drug interacting information, on a display of the device according to genome browsing constraints. | 10-29-2015 |
20160026752 | Systems And Methods For Comprehensive Analysis Of Molecular Profiles Across Multiple Tumor And Germline Exomes - Omics patient data are analyzed using sequences or diff objects of tumor and matched normal tissue to identify patient and disease specific mutations, using transcriptomic data to identify expression levels of the mutated genes, and pathway analysis based on the so obtained omic data to identify specific pathway characteristics for the diseased tissue. Most notably, many different tumors have shared pathway characteristics, and identification of a pathway characteristic of a tumor may thus indicate effective treatment options ordinarily not considered when tumor analysis is based on anatomical tumor type only. | 01-28-2016 |
20160070855 | Systems And Methods For Determination Of Provenance - Systems and methods for genomic analysis are contemplated in which idiosyncratic markers or marker constellations are employed to characterize and compare genomic sequences. In especially preferred aspects, the idiosyncratic markers are predetermined SNPs and a marker profile is used in a sample record to so allow cross reference to other marker profiles of other sequences. | 03-10-2016 |
20160103949 | PARADIGM DRUG RESPONSE NETWORKS - Systems and methods are presented in which omics data from multiple cell or tissue samples are used to identify pathway elements that are associated with a treatment parameter of the cell or tissue (e.g., resistance towards a specific drug). So identified pathway elements are then modulated in silico in a statistical factor graph model to provide a modified data set that is re-evaluated with respect to the treatment parameter. Such systems and models are particularly useful for recommendation of multi-drug treatments for treatment-nave patients. | 04-14-2016 |
Steven Benz, Santa Cruz, CA US
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20160072800 | SYNTHETIC GENOMIC VARIANT-BASED SECURE TRANSACTION DEVICES, SYSTEMS AND METHODS - Various devices, systems, structures and methods are disclosed related to securely authorizing a transaction by synchronizing digital genomic data with associated synthetic genomic variants. An embodiment of the present invention utilizes digital genomic data associated with an entity, such as a person, who may utilize a genome-based security device to complete a transaction. In one embodiment, a person may use a genome-based security device to communicate with an external device over a wireless or other communication interface, synchronize digital genomic data and an associated synthetic variant received from the external device with digital genomic data and associated synthetic variant stored on the genome-based security device. | 03-10-2016 |
Steven M. Benz, Laurel, MD US
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20110100593 | HYBRID HEAT EXCHANGE APPARATUS - A hybrid heat exchange apparatus for indirectly transferring heat between a process fluid and ambient air includes an evaporative heat transfer cell operative in a wet mode or a dry mode, a dry heat transfer cell and a fan. The air may bypass the dry heat transfer cell to flow through a first air passage or may flow through a second air passage through the dry heat transfer cell and in either event, then through the evaporative heat transfer cell. The air may partially flow through and partially bypass the dry heat transfer cell, and then through the evaporative heat transfer cell. The evaporative heat transfer cell optionally may include a direct contact evaporative heat exchanger. Manually or automatically controlling air flow based on ambient conditions provides efficient and economical control of the hybrid heat exchange apparatus, while avoiding problems in freezing conditions. | 05-05-2011 |