Patent application number | Description | Published |
20080221204 | Materials and Methods for Treating Coagulation Disorders - This invention is drawn to compounds which are more easily metabolized by the metabolic drug detoxification systems. Particularly, warfarin analogs which have been designed to include esters within the structure of the compounds are taught. The invention teaches methods of reducing the toxicity of drugs comprising the introduction of ester groups into drugs during the synthesis of the drug. This invention is also drawn to methods of treating coagulation disorders comprising the administration of compounds which have been designed to be metabolized by serum or intracellular hydrolases and esterases. Pharmaceutical compositions of the ester containing warfarin, analogs are also taught. | 09-11-2008 |
20080255088 | DIBENZO[b,f][1,4]OXAZAPINE COMPOUNDS - The present invention relates to 11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazapine compounds of the formula: | 10-16-2008 |
20090082430 | Materials and Methods for Treating Coagulation Disorders - The subject invention provides anticoagulant compounds of formula I: | 03-26-2009 |
20100184815 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA - Disclosed are compounds of the formula: | 07-22-2010 |
20120010228 | D2 ANTAGONISTS, METHODS OF SYNTHESIS AND METHODS OF USE - Provided are D | 01-12-2012 |
20120178738 | DIBENZO [B,F] [1,4]OXAZAPINE COMPOUNDS - The present invention relates to 11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazapine compounds of the formula: | 07-12-2012 |
20130040987 | Stereoisomeric Compounds and Methods for the Treatment of Gastrointestinal and Central Nervous System Disorders - The subject invention provides stereoisomeric compounds of formula (X): | 02-14-2013 |
20140350005 | D2 ANTAGONISTS, METHODS OF SYNTHESIS AND METHODS OF USE - Provided are D | 11-27-2014 |