Alonso Fernandez
Diego Alonso Fernandez, Burgos ES
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20090157364 | Method and system for a quick calculation of aerodynamic forces on an aircraft - A computer-aided method suitable for assisting in the design of an aircraft by providing the dimensioning aerodynamic forces and other relevant values comprising the following steps: a) Selecting a set of parameters of the aircraft, being said aerodynamic forces and other relevant values dependant of said parameters; b) Performing flow field CFD RANS computations for a number N1 of different combination of values of said parameters; c) Obtaining said aerodynamic forces and other relevant values for whatever combination of values of said parameters through a reduced-order model, generated by computing the POD modes of the flow variables, expanding the flow variables using said POD modes and obtaining the POD coefficients of said expanded flow variables using a genetic algorithm that minimizes the error associated to the expansion of the Navier-Stokes equations. The invention also refers to a system for carrying out said method. | 06-18-2009 |
20100106471 | Computer-Aided Method for a Cost-Optimized Calculation of Aerodynamic Forces on an Aircraft - A computer-aided method suitable for assisting in the design of an aircraft by providing the values of dimensional variables, dependant of a predefined set of parameters, for the complete aircraft or an aircraft component, comprising the following steps: a) Defining a parametric space grid; b) Obtaining a suitable Reduced Order Model (ROM) model, particularly a Proper Orthogonal Decomposition (POD) model, for calculating said variables for whatever point over the parametric space through an iterative process. Computer Fluid Dynamics (CFD) is used to calculate said variables for an appropriately selected set of points over the parametric space, which are used to approximate, via ROM and ad hoc interpolation, the variables in any other point over the parametric space. The method minimizes the required number of CFD calculations (to minimize the computational cost, which dramatically depends on this number) for a given level of error. | 04-29-2010 |
Ma Jose Alonso Fernandez, Santiago De Compostela ES
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20080220030 | Nanoparticles Comprising Chitosan and Cyclodextrin - This invention relates to a system comprising nanoparticles designed for the release of biologically active molecules, where the nanoparticles comprise a) at least 40% by weight of chitosan or a derivative thereof and b) less than 60% by weight of a cyclodextrin or a derivative thereof, where both components a) and b) are mixed, without any covalent bond between them. This system allows for the efficient association of biologically active molecules, as well as their subsequent release in a suitable biological environment. | 09-11-2008 |
20090074824 | STABLE NANOCAPSULE SYSTEMS FOR THE ADMINISTRATION OF ACTIVE MOLECULES - The invention is aimed at nanocapsule systems characterized in that they have high stability during long periods of time. These systems are useful for the controlled release of pharmacologically or cosmetically active ingredients of highly lipophilic nature. The system comprises nanocapsules with an average size less than 1 μm dispersed in an aqueous medium, wherein the nanocapsules have a structure which comprises a lipophilic phase containing a phospholipid component and one or more saturated and/or unsaturated C | 03-19-2009 |
20110142890 | NANOPARTICLES OF CHITOSAN AND HYALURONAN FOR THE ADMINISTRATION OF ACTIVE MOLECULES - The present invention relates to a nanoparticulate system useful for the delivery of pharmacologically active molecules, and especially for transfecting polynucleotides into cells. It comprises nanoparticles of chitosan of low molecular weight and hyaluronan. | 06-16-2011 |
Ma Jose Alonso Fernandez, Santiago De Compestela ES
Patent application number | Description | Published |
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20080317864 | Chitosan and Heparin Nanoparticles - The invention is aimed at nanoparticulate systems for the controlled release of heparin. It is specifically aimed at nanoparticulate systems comprising chitosan, heparin and optionally a polyoxyethylenated derivative, and which are ionically cross-linked, as well as being aimed at processes for obtaining them. | 12-25-2008 |