Pinkerton, CA
Andrew Pinkerton, Redwood City, CA US
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20100299977 | FRAME/TEMPLATE FOR SECURING A VIDEO SCREEN TO A GOLF BAG OR OTHER ITEM AND METHOD THEREFOR - A device for displaying advertisements has a plate member. An opening is formed in the plate member, wherein the opening is sized to fit a display screen of a desired dimension. Support arms are coupled to the plate member for securing the device to a storage device to which the device is installed. | 12-02-2010 |
Anothony B. Pinkerton, San Diego, CA US
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20090105124 | HETEROCYCLIC MODULATORS OF TGR5 - Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of modulation of TGR5 activity in a human or animal subject are also provided for the treatment diseases mediated by TGR5. | 04-23-2009 |
Anthony Pinkerton, La Jolla, CA US
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20150329497 | SMALL MOLECULE AGONISTS OF NEUROTENSIN RECEPTOR 1 - Provided herein are small molecule neurotensin receptor agonists, compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds. | 11-19-2015 |
Anthony Pinkerton, San Diego, CA US
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20130012513 | HEDGEHOG INHIBITORS - Described herein are compounds, pharmaceutical compositions and methods for the inhibition of Hedgehog signaling. Said compounds, pharmaceutical compositions and methods have utility in the treatment of human and veterinary disease and disorders. | 01-10-2013 |
20130040983 | RAF KINASE INHIBITORS - Described herein are compounds, pharmaceutical compositions and methods for the inhibition of RAF kinae mediated signaling. Said compounds, pharmaceutical compositions and methods have utility in the treatment of human disease and disorders. | 02-14-2013 |
Anthony B. Pinkerton, San Digo, CA US
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20110166123 | NOVEL COMPOSITIONS AND METHODS OF USE - Described herein are novel enzyme inhibitors. In some embodiments the enzyme inhibitors are integrase inhibitors, particularly HIV integrase inhibitors. Also described herein are compositions containing them and methods of using them. Thus, the compounds and compositions described herein are useful for the in vitro and in vivo inhibition of HIV integrase as a method of treating or preventing HIV, AIDS or related disorders. | 07-07-2011 |
Anthony B. Pinkerton, San Diego, CA US
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20080221161 | HETEROCYCLIC MODULATORS OF TGR5 FOR TREATMENT OF DISEASE - Disclosed herein are compounds useful as modulators of TGR5 and methods for the treatment or prevention of metabolic, cardiovascular, and inflammatory diseases. | 09-11-2008 |
20080293684 | Heterocyclic Acetophenone Potentiators of Metabotropic Glutamate Receptors - The present invention is directed to compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved. | 11-27-2008 |
20080312286 | Indanone Potentiators of Metabotropic Glutamate Receptors - The present invention is directed to compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved. | 12-18-2008 |
20090035306 | QUINAZOLINONE MODULATORS OF TGR5 - The present invention relates to quinazolinone compounds useful as modulators of TGR5 and methods for the treatment or prevention of metabolic, cardiovascular, and inflammatory diseases. | 02-05-2009 |
20090054304 | HETEROCYCLIC MODULATORS OF TGR5 FOR TREATMENT OF DISEASE - The present invention relates to compounds useful as modulators of TGR5 and methods for the treatment or prevention of metabolic, cardiovascular, and inflammatory diseases. | 02-26-2009 |
20090162319 | REVERSE TRANSCRIPTASE INHIBITORS - Described herein are novel enzyme inhibitors. In some embodiments, the enzyme inhibitors are reverse transcriptase inhibitors, particularly HIV reverse transcriptase inhibitors. Also described herein are compositions containing them and methods of using them. Thus, the compounds and compositions described herein are useful for the in vitro and in vivo inhibition of HIV reverse transcriptase as a method of treating or preventing HIV, AIDS or related disorders. | 06-25-2009 |
20110269741 | NOVEL COMPOSITIONS AND METHODS OF USE - Described herein are novel enzyme inhibitors. In some embodiments the enzyme inhibitors are integrase inhibitors, particularly HIV integrase inhibitors. Also described herein are compositions containing them and methods of using them. Thus, the compounds and compositions described herein are useful for the in vitro and in vivo inhibition of HIV integrase as a method of treating or preventing HIV, AIDS or related disorders. | 11-03-2011 |
20120277206 | REVERSE TRANSCRIPTASE INHIBITORS - Described herein are novel enzyme inhibitors. In some embodiments, the enzyme inhibitors are reverse transcriptase inhibitors, particularly HIV reverse transcriptase inhibitors. Also described herein are compositions containing them and methods of using them. Thus, the compounds and compositions described herein are useful for the in vitro and in vivo inhibition of HIV reverse transcriptase as a method of treating or preventing HIV, AIDS or related disorders. | 11-01-2012 |
20140005181 | SMALL MOLECULE ANTAGONISTS OF THE APELIN RECEPTOR FOR THE TREATMENT OF DISEASE | 01-02-2014 |
20150203477 | COMPOUNDS AND METHODS FOR ACTIVATING THE APOPTOTIC ARM OF THE UNFOLDED PROTEIN RESPONSE - N-substituted sulfonylphenyl-5-nitrofuranyl-2-carboxamide derived compounds, which selectively activate the apoptotic, but not the adaptive arm, of the Unfolded Protein Response are provides as is their use in the treatment of diseases such as diabetes, Alzheimer's, Parkinson's, hemophilia, lysosomal storage diseases and cancer. | 07-23-2015 |
Brian Pinkerton, Woodside, CA US
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20080228695 | TECHNIQUES FOR ANALYZING AND PRESENTING INFORMATION IN AN EVENT-BASED DATA AGGREGATION SYSTEM - Methods and apparatus are described for presenting information relating to event-based data aggregated in an event-based data aggregation system. A dashboard interface is presented which includes report summary data for each of a plurality of reports to which a user has access. Each report corresponds to a subset of the event-based data derived with reference to an associated report rule set. At least one of the report rules sets is editable by the user. The report summary data are updated in response to detection of new event-based data being added to the event-based data aggregation system which match a first one of the report rule sets. | 09-18-2008 |
Kent E. Pinkerton, Davis, CA US
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20100317733 | USE OF CIS-EPOXYEICOSANTRIENOIC ACIDS AND INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE TO REDUCE PULMONARY INFILTRATION BY NEUTROPHILS - It has now been discovered that inhibitors of soluble epoxide hydrolase (“sEH”) are useful in reducing the severity of or inhibiting the progression of obstructive pulmonary diseases, restrictive airway diseases, and asthma. Administering a cis-epoxyeicosantrienoic acid (“EET”) in addition to the inhibitor is at least additive, and may be synergistic, in reducing or inhibiting these conditions and diseases, as measured by reduced numbers of neutrophils present in the lung. The inhibitor of sEH may be a nucleic acid, such as a small interfering RNA. | 12-16-2010 |
Robert Brent Pinkerton, San Francisco, CA US
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20130227046 | METHOD AND SYSTEM FOR PROCESSING INTELLIGENCE INFORMATION - A method and system for routing intelligence information related to security. The security system provides rules that identify conditions and routing instructions that are to be applied to intelligence information. A security organization may create and modify rules to ensure the appropriate routing of intelligence information in a timely manner. The security system may receive intelligence information from various sources. Regardless of the form or source of intelligence information, the security system analyzes the intelligence information to determine whether any conditions of the rules are satisfied. When a condition of a rule is satisfied, the security system sends a notification of the intelligence information in accordance with the routing instructions for that rule. In this way, intelligence information can be automatically and quickly routed to the appropriate security personnel for further processing. | 08-29-2013 |
Robert N. Pinkerton, Hemet, CA US
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20100224275 | FLOW STRAIGHTENING APPARATUS - An apparatus for straightening fluid flow in a conduit or pipeline, such as an irrigation pipeline, resides in an integral assembly of a conical fluid flow displacement member effective to substantially lineralize the velocity profile of fluid flowing through the pipeline and a plurality of circumferentially spaced vanes extending longitudinally and radially of the conical member and effective to mitigate swirl and eccentric velocity profiles in the flowing fluid. The conical member consists simply of a single cone that is centered in the pipeline by the vanes. A bolt extending through the wall of the pipe and threaded into a nut on a vane secures the straightener in the line. | 09-09-2010 |
Stephanie A. Pinkerton, San Diego, CA US
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20150238631 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF - Disclosed herein are switches for regulating the activity of a chimeric antigen receptor effector cells (CAR-ECs). The switches generally comprise a chimeric antigen receptor-interacting domain (CAR-ID) and a target interacting domain (TID). The switch may further comprise a linker. Further disclosed herein are methods of using the switches for the treatment of one or more conditions or diseases in a subject in need thereof. | 08-27-2015 |