Patent application number | Description | Published |
20090125518 | Collaborative Authoring - A collaborative authoring application provides an authoring environment in which two or more users can edit a document concurrently. Each user edits a copy of the document, sends updates to a master copy of the document, and receives updates from the master copy of the document. The authoring environment generally inhibits the users from providing conflicting editing instructions to the master copy of the document. For example, each user can generate a content lock about one or more data units within the document. The authoring environment may synchronize content locks automatically and content only at the request of the user. | 05-14-2009 |
20090150394 | Document Merge - Methods and systems of merging a first document with at least a second document to generate a third document. Each of the first and second documents includes at least one data unit. Each data unit is associated with a unit identifier and an edit identifier. The unit identifiers of each of the documents are compared to the unit identifiers of the other document to determine whether each unit identifier is a matching or non-matching unit identifier. Edit identifiers of the data units associated with the matching unit identifiers are compared to each other. Data units associated with the non-matching unit identifiers are inserted directly into the third document. Data units associated with the matching unit identifiers and the matching edit identifiers are inserted directly into the third document. Data units associated with the matching unit identifiers and the non-matching edit identifiers are merged into the third document. | 06-11-2009 |
20090157811 | Collaborative Authoring Modes - A collaborative authoring application provides an authoring environment in which two or more users can edit a document concurrently. Each user edits a copy of the document, sends updates to a master copy of the document, and receives updates from the master copy of the document. The authoring environment may be configured into a public mode of operation, in which content and metadata are synchronized automatically, or into a private mode of operation, in which metadata is synchronized automatically and content is synchronized only at the request of the user. The authoring application may edit documents offline in public or private mode. | 06-18-2009 |
20090271696 | Conflict Resolution - Embodiments of a collaborative authoring environment enable a user to resolve editing conflicts arising when synchronizing a user copy of a data file with a master copy of the data file. Content updates may be synchronized separately from metadata updates. Metadata updates may be synchronized automatically, whereas content updates may be synchronized only when any identified editing conflicts are resolved. When an editing conflict is identified, the user interface of the authoring application may be configured to toggle between displaying and hiding the identified editing conflicts. | 10-29-2009 |
20100211543 | SYNCHRONIZING METADATA AND DOCUMENT CONTENT ACROSS CLIENT SYSTEMS USING DIFFERENT COMMUNICATION CHANNELS - Tools and techniques for synchronizing metadata and document content across client systems using different communication channels are provided. These tools may define logical communication channels between client software components, and may allocate one of these channels to synchronizing updates to the contents of documents shared between these client components. These tools may allocate another one of the communication channels to synchronizing metadata between the client components, with the metadata describing activity pertaining to the shared documents. The client components may receive indications of activity made by users to the document contents, and may create metadata representing the activity. These client components may then transmit this metadata, using the further communication channel, to any number of other client components automatically in real time with the updates. | 08-19-2010 |
20110184906 | Client Side Locking - A collaborative authoring application provides an authoring environment in which two or more users can edit a document concurrently. Each user edits a copy of the document, sends updates to a master copy of the document, and receives updates from the master copy of the document. The authoring environment generally inhibits the users from providing conflicting editing instructions to the master copy of the document. For example, each user can generate a content lock about one or more data units within the document. The authoring environment may synchronize content locks automatically and content only at the request of the user. | 07-28-2011 |
20120278276 | Collaborative Authoring - A collaborative authoring application provides an authoring environment in which two or more users can edit a document concurrently. Each user edits a copy of the document, sends updates to a master copy of the document, and receives updates from the master copy of the document. The authoring environment generally inhibits the users from providing conflicting editing instructions to the master copy of the document. For example, each user can generate a content lock about one or more data units within the document. The authoring environment may synchronize content locks automatically and content only at the request of the user. | 11-01-2012 |
20130013997 | Conflict Resolution - Embodiments of a collaborative authoring environment enable a user to resolve editing conflicts arising when synchronizing a user copy of a data file with a master copy of the data file. Content updates may be synchronized separately from metadata updates. Metadata updates may be synchronized automatically, whereas content updates may be synchronized only when any identified editing conflicts are resolved. When an editing conflict is identified, the user interface of the authoring application may be configured to toggle between displaying and hiding the identified editing conflicts. | 01-10-2013 |
20140373108 | COLLABORATIVE AUTHORING MODES - A collaborative authoring application provides an authoring environment in which two or more users can edit a document concurrently. Each user edits a copy of the document, sends updates to a master copy of the document, and receives updates from the master copy of the document. The authoring environment may be configured into a public mode of operation, in which content and metadata are synchronized automatically, or into a private mode of operation, in which metadata is synchronized automatically and content is synchronized only at the request of the user. The authoring application may edit documents offline in public or private mode. | 12-18-2014 |
20150067467 | COLLABORATIVE AUTHORING - A collaborative authoring application provides an authoring environment in which two or more users can edit a document concurrently. Each user edits a copy of the document, sends updates to a master copy of the document, and receives updates from the master copy of the document. The authoring environment generally inhibits the users from providing conflicting editing instructions to the master copy of the document. For example, each user can generate a content lock about one or more data units within the document. The authoring environment may synchronize content locks automatically and content only at the request of the user. | 03-05-2015 |
Patent application number | Description | Published |
20090022696 | METHODS FOR IMMORTALIZING CELLS - The present invention provides methods for immortalizing precursor cells that are non-terminally differentiated cells such as stem cells, said methods comprising culturing the precursor cells in the presence of a Notch agonist and one or more growth factors that support the proliferation but not differentiation of the non-terminally differentiated cells. The present invention further provides methods to induce the differentiation of immortalized cells, comprising growing the cells in the presence of a Notch agonist and at least one growth factor which supports the differentiation of the cell into a more specialized cell type. The immortalized and/or differentiated cells of the invention can be used to repopulate cell populations that have been diminished, for example as a result of infection or exposure to certain drugs. The invention further provides a cell culture comprising a population of non-terminally differentiated cells immortalized by the methods of the present invention and kits comprising reagents that promote the immortalization of precursor cells. The invention further provides methods for screening for Notch modulators and for identifying genes involved in processes of cellular differentiation. | 01-22-2009 |
20130095079 | COMPOSITIONS AND METHODS FOR PROVIDING HEMATOPOIETIC FUNCTION WITHOUT HLA MATCHING - The present invention relates to methods and compositions for providing hematopoietic function in immunodeficient human patients, by selecting an expanded human umbilical cord blood stem/progenitor cell sample without taking into account the HLA-type of the expanded human cord blood stem/progenitor sample or the HLA-type of the patient; and administering the selected expanded human cord blood stem/progenitor cell sample to the patient. Methods for obtaining the expanded human cord blood stem/progenitor cell samples, banks of frozen expanded human cord blood stem/progenitor cell samples, and methods for producing such banks are also provided herein. | 04-18-2013 |
20130095080 | COMPOSITIONS AND METHODS FOR PROVIDING HEMATOPOIETIC FUNCTION - The present invention relates to methods and compositions for providing hematopoietic function to human patients in need thereof, by selecting a pool of expanded human cord blood stem/progenitor cell samples for administration to the patient, wherein the samples in the pool collectively do not mismatch the patient at more than 2 of the HLA antigens or alleles typed in the patient; and administering the selected pool of expanded human cord blood stem/progenitor cell samples to the patient. Methods for obtaining the pools of expanded human cord blood stem/pro-genitor cell samples, banks of frozen pools of expanded human umbilical cord blood stem/progenitor cell samples, and methods for producing such banks are also provided herein. | 04-18-2013 |
20140369973 | COMPOSITIONS AND METHODS FOR ENHANCED GENERATION OF HEMATOPOIETIC STEM/PROGENITOR CELLS - The present invention relates to methods, kits and compositions for expansion of hematopoietic stem/progenitor cells and providing hematopoietic function to human patients in need thereof. In one aspect, it relates to kits and compositions comprising a Notch agonist and an aryl hydrocarbon receptor antagonist. Also provided herein are methods for expanding the hematopoietic stem/progenitor cells using kits and compositions comprising a Notch agonist and an aryl hydrocarbon receptor antagonist. The hematopoietic stem/progenitor cells expanded using the disclosed kits, compositions and methods include human umbilical cord blood stem/progenitor cells, placental cord blood stem/progenitor cells and peripheral blood stem cells. The present invention also relates to administering hematopoietic stem/progenitor cells expanded using a combination of a Notch agonist and an aryl hydrocarbon receptor antagonist to a patient for short-term and/or long-term in vivo repopulation benefits. | 12-18-2014 |
Patent application number | Description | Published |
20090150367 | MAPPING AND QUERY TRANSLATION BETWEEN XML, OBJECTS, AND RELATIONS - Described is programmatic access to persistent XML and relational data from applications based upon explicit mappings between object classes, XML schema types, and relations. The mappings are used in data access, that is, they drive query and update processing. A query may be processed into a query for accessing the XML data and another query for second type for accessing the relational data. Mappings support strongly-typed classes and loosely-typed classes, and may be conditional upon other data, may decouple query and update translation performed at runtime from schema translation used at compile time, and/or may be compiled into transformations that produce objects from XML data and transformations that produce XML data from objects. Mappings may be generated automatically or provided by the developer. | 06-11-2009 |
20100191919 | APPEND-BASED SHARED PERSISTENT STORAGE - A shared storage system is described herein that is based on an append-only model of updating a storage device to allow multiple computers to access storage with lighter-weight synchronization than traditional systems and to reduce wear on flash-based storage devices. Appending data allows multiple computers to write to the same storage device without interference and without synchronization between the computers. Computers can also safely read a written page without using synchronization because the system limits how data can be changed once written. The system may record a log of append operations performed and ensure idempotence by storing a key specified by the caller in the log along with each log entry. The system also provides broadcasts about appended data to computers so that coordination between computers can occur without direct communication between the computers. | 07-29-2010 |
20100268876 | SLIDING-WINDOW MULTI-CLASS STRIPING - A sequence of storage devices of a data store may include one or more stripesets for storing data stripes of different lengths and of different types. Each data stripe may be stored in a prefix or other portion of a stripeset. Each data stripe may be identified by an array of addresses that identify each page of the data stripe on each included storage device. When a first storage device of a stripeset becomes full, the stripeset may be shifted by removing the full storage device from the stripeset, and adding a next storage device of the data store to the stripeset. A class variable may be associated with storage devices of a stripeset to identify the type of data that the stripeset can store. The class variable may be increased (or otherwise modified) when a computer stores data of a different class in the stripeset. | 10-21-2010 |
20100274821 | Schema Matching Using Clicklogs - Techniques described herein describe a schema and taxonomy matching process that uses clicklogs to map a schema for source data to a schema for target data. A search engine may receive source data that is structured using the source schema, and the search engine itself may contain target data structured using the target schema. Using query distributions derived from the clicklogs, the source schema may be mapped to the target schema. The mapping can be used to integrate the source data into the target data and to index the integrated data for a search engine. | 10-28-2010 |
20110238813 | CONSISTENT CLUSTER OPERATIONAL DATA IN A SERVER CLUSTER USING A QUORUM OF REPLICAS - A method and system for increasing server cluster availability by requiring at a minimum only one node and a quorum replica set of replica members to form and operate a cluster. Replica members maintain cluster operational data. A cluster operates when one node possesses a majority of replica members, which ensures that any new or surviving cluster includes consistent cluster operational data via at least one replica member from the immediately prior cluster. Arbitration provides exclusive ownership by one node of the replica members, including at cluster formation, and when the owning node fails. Arbitration uses a fast mutual exclusion algorithm and a reservation mechanism to challenge for and defend the exclusive reservation of each member. A quorum replica set algorithm brings members online and offline with data consistency, including updating unreconciled replica members, and ensures consistent read and update operations. | 09-29-2011 |
20110238842 | CONSISTENT CLUSTER OPERATIONAL DATA IN A SERVER CLUSTER USING A QUORUM OF REPLICAS - A method and system for increasing server cluster availability by requiring at a minimum only one node and a quorum replica set of replica members to form and operate a cluster. Replica members maintain cluster operational data. A cluster operates when one node possesses a majority of replica members, which ensures that any new or surviving cluster includes consistent cluster operational data via at least one replica member from the immediately prior cluster. Arbitration provides exclusive ownership by one node of the replica members, including at cluster formation, and when the owning node fails. Arbitration uses a fast mutual exclusion algorithm and a reservation mechanism to challenge for and defend the exclusive reservation of each member. A quorum replica set algorithm brings members online and offline with data consistency, including updating unreconciled replica members, and ensures consistent read and update operations. | 09-29-2011 |
20110289118 | MAPPING DOCUMENTS TO A RELATIONAL DATABASE TABLE WITH A DOCUMENT POSITION COLUMN - Architecture that maps document data (e.g., XML-extended markup language) into columns of one table, thereby avoiding schema normalization problems through special data storage. Moreover, an algorithm is described that can translate a query (e.g., in XPath (XML path language), a query language for navigating through document elements and attributes of an XML document) into a relational algebra query of the document column representation. Based on the characteristics of the new mapping, query rewriting rules are provided that optimize the relational algebra query by minimizing the number of joins. The mapping of XML documents to the table is based on a summary structure and a hierarchical labeling scheme (e.g., ordpath) to enable a high-fidelity representation. Annotations are employed on the summary structure nodes to assist in mapping XML elements and attributes to the table. | 11-24-2011 |
20110295969 | TOTALLY ORDERED LOG ON APPENDABLE STORAGE - Computers are provided with a totally ordered, durable shared log. Shared storage is used and can be directly accessed by the computers over a network. Append-log operations are made atomic in the face of failures by committing provisional append ordering information onto a log. The log may comprise multiple flash packages or non-volatile memory devices, referred to as segments, although any shared storage device(s) may be used. Each log record is a multi-page stripe, where each page of a stripe is written to a different segment. Fault-tolerant protocol variants append stripes to the log, such that stripes are totally ordered in the log and each stripe is written atomically. | 12-01-2011 |
20110307501 | Automating Evolution of Schemas and Mappings - Aspects of the subject matter described herein relate to automating evolution of schemas and mappings. In aspects, mappings between a conceptual model and a store model are updated automatically in response to a change that occurs to the conceptual model. For example, when a change occurs to the conceptual model, a local scope of the change is determined. The local scope indicates mappings that are most similar to the type(s) affected by the change. Based on the local scope, a pattern of mappings between the conceptual model and the store model is determined. Using this pattern and the nature of the change, the mappings are updated according to the pattern. In addition, the store model and data thereon may be updated in a manner to preserve existing data that is not to be deleted in response to the change. | 12-15-2011 |
20110314043 | FULL-FIDELITY REPRESENTATION OF XML-REPRESENTED OBJECTS - A data structure may exist in various representations, such as an object in an object-oriented system or a set of elements included in an extensible markup language (XML) document structured according to an XML type defined in an XML schema. While many aspects of these representations may correspond, some aspects of an XML document may not be specified by the XML schema (such as developer comments, whitespace, and preprocessor directives), and may be lost while translating an XML representation of the data structure to an object. These non-schematized aspects may be included in the object as a delta, specifying the location of an aspect with relation to an element defined by the XML schema. Preserving non-schematized aspects may promote the full representation of the data structure as an object, and may facilitate a full-fidelity regeneration of the XML document from which the object was generated. | 12-22-2011 |
20110320496 | CONCURRENCY CONTROL FOR CONFLUENT TREES - Architecture that addresses the efficient detection of conflicts and the merging of data structures such as trees, when possible. The process of detecting conflicts and merging the trees is a meld operation. Confluent trees offer transactional consistency with some degree of isolation, and scaling out a concurrent system based on confluent trees can be accomplished where the meld operation is more efficient than the transaction computations. Transactions execute optimistically using lazily versioned “intention trees” that efficiently describe dependencies and effects using structure and content version information for each intention subtree. The data structure is modified by melding the intention trees in sequence, which causes each transaction to either commit (producing an incremental new version of the data structure) or abort (identifying a conflict which prevents the intention tree from being melded). The architecture is computationally efficient and completes without needing to access much of each tree. | 12-29-2011 |
20120265734 | INCREMENTAL COMPILATION OF OBJECT-TO-RELATIONAL MAPPINGS - Aspects of the subject matter described herein relate to incrementally modifying schemas and mappings. In aspects, an indication of a change to a client schema is received and a compilation directive is received. The compilation directive may indicate how one or more entities or associations in the client schema are to be mapped to the store schema. In response to receiving the indication of the change and the compilation directive, mapping data and storage schema may be incrementally modified with incremental revalidation and incremental updating of query and update views. | 10-18-2012 |
20130232118 | SHARED LOG-STRUCTURED MULTI-VERSION TRANSACTIONAL DATASTORE WITH METADATA TO ENABLE MELDING TREES - Architecture that includes an ordered and shared log of indexed transaction records represented as multi-version data structures of nodes and node pointers. The log is a sole monolithic source of datastore state and is used for enforcing concurrency control. The architecture also includes a transaction processing component that appends transaction records to the log from concurrent transactions executing on different processors. Each node of a record is assigned a log address. | 09-05-2013 |
20130238853 | SLIDING-WINDOW MULTI-CLASS STRIPING - A sequence of storage devices of a data store may include one or more stripesets for storing data stripes of different lengths and of different types. Each data stripe may be stored in a prefix or other portion of a stripeset. Each data stripe may be identified by an array of addresses that identify each page of the data stripe on each included storage device. When a first storage device of a stripeset becomes full, the stripeset may be shifted by removing the full storage device from the stripeset, and adding a next storage device of the data store to the stripeset. A class variable may be associated with storage devices of a stripeset to identify the type of data that the stripeset can store. The class variable may be increased (or otherwise modified) when a computer stores data of a different class in the stripeset. | 09-12-2013 |
20130275474 | Automating Evolution of Schemas and Mappings - Aspects of the subject matter described herein relate to automating evolution of schemas and mappings. In aspects, mappings between a conceptual model and a store model are updated automatically in response to a change that occurs to the conceptual model. For example, when a change occurs to the conceptual model, a local scope of the change is determined. The local scope indicates mappings that are most similar to the type(s) affected by the change. Based on the local scope, a pattern of mappings between the conceptual model and the store model is determined. Using this pattern and the nature of the change, the mappings are updated according to the pattern. In addition, the store model and data thereon may be updated in a manner to preserve existing data that is not to be deleted in response to the change. | 10-17-2013 |
20130332435 | PARTITIONING OPTIMISTIC CONCURRENCY CONTROL AND LOGGING - Parallel certification of transactions on shared data stored in database partitions included in an approximate database partitioning arrangement may be initiated, based on initiating a plurality of certification algorithm executions in parallel, and providing a sequential certifier effect. Logging operations associated with a plurality of log partitions configured to store transaction objects associated with each respective transaction may be initiated, each respective database partition included in the approximate database partitioning being associated with one or more of the log partitions. A scheduler may assign each of the transactions to a selected one of the certification algorithm executions. | 12-12-2013 |