Payack
Joseph Payack, Newbury Park, CA US
Patent application number | Description | Published |
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20090203922 | Process for Synthesizing 2-Phenyl-1H-Phenanthro[9,10-d]Imidazole Derivative - The present invention describes an efficient and economical process for the preparation of a 2,3-disubstituted 2-phenyl-1h-phenantrho[9,10-d]imidazole derivative that is useful for the large scale production of material for preclinical and clinical use. The process of the present invention represents a convergent approach to generate the 2,3-disubstituted 2-phenyl-1h-phenantrho[9,10-d]imidazole derivative in high overall yield. The compound made by the process of the invention is an inhibitor of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and is therefore useful to treat pain and/or inflammation from a variety of diseases or conditions, such as osteoarthritis, rheumatoid arthritis and acute or chronic pain. | 08-13-2009 |
Joseph F. Payack, Somerset, NJ US
Patent application number | Description | Published |
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20090149454 | Benzomorpholine derivatives and methods of use - Selected benzomorpholine compounds are effective for prophylaxis and treatment of diseases, such as VEGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. | 06-11-2009 |
20090275659 | Phenyl acetic acid derivatives as inflammation modulators - Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of inflammatory and immune-related diseases and conditions. In particular, the invention provides compounds which modulate the function and/or expression of proteins involved in atopic diseases, inflammatory conditions and cancer. The subject compounds are carboxylic acid derivatives. | 11-05-2009 |
Joseph Francis Payack, Somerset, NJ US
Patent application number | Description | Published |
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20130030178 | METHODS OF MAKING HIV ATTACHMENT INHIBITOR PRODRUG COMPOUND AND INTERMEDIATES - A method for making the compound of Formula I: | 01-31-2013 |
Walter Payack, Duluth, GA US
Patent application number | Description | Published |
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20100133922 | Integrated Automatic Selection of Maintenance Mode in Electronic Tripping Systems to Minimize Arc Fault Energy - A monitor control system and method for an electrical distribution system includes a trip unit of a circuit breaker. A sensor is associated with the electrical distribution system and coupled to the trip unit wherein the sensor is connected to one or more components of the electrical distribution system to detect whether the electrical distribution system is being serviced when a presence of a human being is also detected. A selector is coupled to the trip unit and configured to select maintenance mode parameters to define a mode of operation of the trip unit wherein in the maintenance mode arc flash reduction or tripping delay reduction is provided such that the trip unit operates based on the maintenance mode parameters. | 06-03-2010 |