Patent application number | Description | Published |
20100174048 | Processes for Preparing a Polypeptide - The present invention relates to an improved process for preparing a polypeptide or pharmaceutically acceptable salt thereof comprising L-tyrosine, L-alanine, L-glutamate, and L-lysine. The polypeptide or pharmaceutically acceptable salt thereof is preferably glatiramer acetate. The process comprises: (a) polymerizing a mixture of N-carboxyanhydride of L-tyrosine, N-carboxyanhydride of L-alanine, N-carboxyanhydride of a protected L-glutamate and N-carboxyanhydride of a protected L-lysine, in a polar aprotic solvent in the presence of an initiator, to form a protected polypeptide; (b) admixing an acid with the protected polypeptide formed in Step (a) and a solvent, to form a product; and (c) admixing a substance selected from the group consisting of an alkali or alkaline earth metal hydroxide, a carbonate, a hydrogencarbonate, and mixtures thereof, with the product formed in Step (b), and a solvent or a mixture of a solvent and water, to form a deprotected polypeptide or a pharmaceutically acceptable salt thereof. | 07-08-2010 |
20100234272 | Processes for Preparing a Polypeptide - The present invention relates to an improved process for preparing a polypeptide or pharmaceutically acceptable salt thereof comprising L-tyrosine, L-alanine, L-glutamate, and L-lysine. The polypeptide or pharmaceutically acceptable salt thereof is preferably glatiramer acetate. The process comprises: (a) polymerizing a mixture of N-carboxyanhydride of L-tyrosine, N-carboxyanhydride of L-alanine, N-carboxyanhydride of a protected L-glutamate and N-carboxyanhydride of a protected L-lysine, in a polar aprotic solvent in the presence of an initiator, to form a protected polypeptide; (b) admixing an acid with the protected polypeptide formed in Step (a) and a solvent, to form a product; and (c) admixing a substance selected from the group consisting of an alkali or alkaline earth metal hydroxide, a carbonate, a hydrogencarbonate, and mixtures thereof, with the product formed in Step (b), and a solvent or a mixture of a solvent and water, to form a deprotected polypeptide or a pharmaceutically acceptable salt thereof. | 09-16-2010 |
20100234566 | Processes for Preparing a Polypeptide - The present invention relates to an improved process for preparing a polypeptide or pharmaceutically acceptable salt thereof comprising L-tyrosine, L-alanine, L-glutamate, and L-lysine. The polypeptide or pharmaceutically acceptable salt thereof is preferably glatiramer acetate. The process comprises: (a) polymerizing a mixture of N-carboxyanhydride of L-tyrosine, N-carboxyanhydride of L-alanine, N-carboxyanhydride of a protected L-glutamate and N-carboxyanhydride of a protected L-lysine, in a polar aprotic solvent in the presence of an initiator, to form a protected polypeptide; (b) admixing an acid with the protected polypeptide formed in Step (a) and a solvent, to form a product; and (c) admixing a substance selected from the group consisting of an alkali or alkaline earth metal hydroxide, a carbonate, a hydrogencarbonate, and mixtures thereof, with the product formed in Step (b), and a solvent or a mixture of a solvent and water, to form a deprotected polypeptide or a pharmaceuticaly acceptable salt thereof. | 09-16-2010 |
Patent application number | Description | Published |
20090147307 | METHOD AND APPARATUS FOR ANALYZING USAGE OF PRINTERS - The present invention provides a method and apparatus for analyzing usage of printers. A method in accordance with an embodiment includes: obtaining from at least one printer information about a plurality of print tasks performed by each printer, wherein the information about print tasks at least contains information of print requesters, print document attributes, and print time of each of the print tasks; and transforming the information about print tasks into an organizational representation based on information of organizational structure containing the print requesters. In the present invention, entities having a costly pattern are identified by mining historical usage data of the printers, thus driving the redesign of business process associated with the entities, performing print policies optimization on each entity associated with the printers based on the mined historical usage data, thereby reducing unnecessary paper consumption. | 06-11-2009 |
20120011082 | GOVERNANCE OF MODELING SYSTEMS - A governing modeling system maintains information associated with an analytic model. One or more policies may be defined that are associated with the analytic model and one or more instances of the analytic model. The system may monitor the analytic model and the one or more instances of the analytic model based on at least some of the information, the one or more policies associated with the analytic model and the one or more policies associated with the one or more instances of the analytic model. | 01-12-2012 |
20120250089 | METHOD FOR ANALYZING USAGE OF PRINTERS - The present invention provides a method for analyzing usage of printers. A method in accordance with an embodiment includes: obtaining from at least one printer information about a plurality of print tasks performed by each printer, wherein the information about print tasks at least contains information of print requesters, print document attributes, and print time of each of the print tasks; and transforming the information about print tasks into an organizational representation based on information of organizational structure containing the print requesters. In the present invention, entities having a costly pattern are identified by mining historical usage data of the printers, thus driving the redesign of business process associated with the entities, performing print policies optimization on each entity associated with the printers based on the mined historical usage data, thereby reducing unnecessary paper consumption. | 10-04-2012 |
Patent application number | Description | Published |
20100179847 | SYSTEM AND METHOD FOR CREATING AND EXPRESSING RISK-EXTENDED BUSINESS PROCESS MODELS - A method and computer program product for integrating risk management concepts into a standard business process metamodel by defining a set of metamodel extensions to standard process modeling languages that incorporate risk information directly in the process model. The method includes collecting risk-relevant information for addition to a business process model, and enabling visualizing of a risk-extended business process model. using a notation to express notions as failure modes of resources, root cause events, and sources of execution failure and low job output quality directly in the context of process models. Additionally, the method enables the computation of risk-related impacts on the distribution of process performance measures using a Bayesian network model or a discrete-event simulation model. | 07-15-2010 |
20110320276 | SYSTEM AND METHOD FOR ONLINE MEDIA RECOMMENDATIONS BASED ON USAGE ANALYSIS - An online recommendation system, method and computer program product for recommending on-line item(s) including a recommended a usage for the on-line item(s). The recommendation method includes capturing, for one or more users at a respective client device, usage characteristics of each users' navigation to and use of one or more items, from among a plurality of items of an item set, on-line, via a respective user interface; obtaining corresponding profile information for each respective user, the profile information including user attributes; storing the usage characteristics and corresponding profile information of each of one or more users; and, for a current user navigating online to the set of items: deriving an item usage recommendation for the current online user based on items of the item set navigated to and used by other online users having similar profiles; and, recommending for the current user, via that current user's user interface, an on-line item and its suggested usage from among the set of items. | 12-29-2011 |
20120016714 | SYSTEM AND METHOD FOR COLLABORATIVE MANAGEMENT OF ENTERPRISE RISK - A method and system for collaboratively managing risk is presented. In one embodiment the method comprises analyzing a node in a risk network when an output of said node violates a control limit, identifying a cause of said violation of said control limit, creating a mitigation action in response to said node violating said control limit, performing said mitigation action, said mitigation action having an influence on said output of said node, and measuring said output of said node to determine effectiveness of said mitigation action on said node, wherein a program using a processor unit executes one or more of said analyzing, identifying, creating, performing and measuring steps. | 01-19-2012 |
20120116850 | CAUSAL MODELING OF MULTI-DIMENSIONAL HIERACHICAL METRIC CUBES - A computing system initializes a first frontier to be a root of a multi-dimensional hierarchical data structure representing an entity. The system acquires first data corresponding to the first frontier. The system performs modeling on the first data to obtain a first model and a corresponding first statistic. The system expands a dimension of the first frontier. The system gathers second data corresponding to the expanded frontier. The system applies the data modeling on the second data to obtain a second model and a corresponding second statistic. The system compares the first statistic of the first model and the second statistic of the second model. The system sets the second model to be the first model in response to determining that the second model statistic is better than the first model statistic. The system outputs the first model. | 05-10-2012 |
20150029870 | BOUNDED-BUDGET MONITOR DEPLOYMENT IN MONITORING NETWORKS VIA END-TO-END PROBES - The present disclosure relates generally to mechanisms for bounded-budget monitor deployment in monitoring networks via end-to-end probes. In various embodiments, methodologies may be provided that automatically perform bounded-budget monitor deployment in monitoring networks via end-to-end probes. | 01-29-2015 |
20150032500 | METHOD FOR CREATING AND EXPRESSING RISK-EXTENDED BUSINESS PROCESS MODELS - A method and computer program product for extending a business process model. The method includes specifying first elements representing performance measures and objectives of a business process which may be compromised by risk events; specifying second elements representing contextual information describing circumstances which may be relevant to a failure mode of the process, said contextual information comprising a type and state of: resources to support the process, of jobs and artifacts that undergo the process; and, a type and state of environmental factors; specifying third elements representing errors which may occur during process execution; specifying fourth elements representing causal relationships among risk events related to the resources, activities, and said environmental factors that may influence process execution; and providing a set of metamodel extensions to a standard process modeling language that incorporate said specified first second third and fourth elements directly in the business process model. | 01-29-2015 |
20150039548 | COLLECTIVE EVALUATION OF ALTERNATIVES IN A COLLABORATIVE DECISION MAKING ENVIRONMENT - A system, method and computer program product for facilitating collaborative decision making may be provided. The system receives data representing individual postings of users associated with a deliberation to make a decision. The system further receives ratings associated with the individual postings in order to make the decision. The system represents the received data in a hierarchical data structure. The system aggregates, through the hierarchical data structure, the ratings associated with the individual postings to obtain strength values. The system facilitates the making of the decision based on the aggregated strength values. | 02-05-2015 |
Patent application number | Description | Published |
20090201533 | SYSTEM AND METHOD FOR CREATING AN EFFICIENT SHIPPING STRATEGY FOR SHIPPING PRINTED MATERIAL - A system and related method for creating an efficient shipping strategy for shipping printed material is disclosed. The system includes a communication component, an analysis component and a shipping component. The communication component communicates printing instructions. The printing instructions include image data and at least one job parameter. The analysis component communicates with the communication component and determines at least one physical property of a print job when formed according to the printing instructions. The shipping component generates shipping information in accordance with the at least one physical property. | 08-13-2009 |
20100151433 | TEST AND ANSWER KEY GENERATION SYSTEM AND METHOD - A system and method for generating a test and an answer key to identify correct answers is disclosed. A test can be created by entering a set of questions with answer choices and correct answers at the same time. The tests can be rendered via a rendering device that includes both the questions and the answer choices. A ticket can be generated that drives a CNC (computer numerically control) machine to create a punched answer key with holes that align over correct answers. The answer key can also be rendered on a transparency utilizing a solid color everywhere except an area where the correct answer should be marked. The test and the answer key can also be rendered and aligned side by side in order to identify correct answers. | 06-17-2010 |
20100214590 | METHOD FOR PROTECTING CONTENT OF A FAX CONFIRMATION SHEET - What is provided are a system, method, and computer program product for protecting information displayed on a fax confirmation page. Several embodiments are provided. In one embodiment, for example, a Gaussian kernel is used to blur the digitized image to be printed on the confirmation page. In one method, a large enough blur kernel is selected so that text of a certain size will be rendered illegible. A method is also provided wherein a copy of the first page of the faxed document used to provide the content to be displayed on the confirmation page of the faxed document is stored on a storage device. A character sequence which references the stored original content on the storage media is printed on the confirmation page. A new confirmation page can be reconstructed and printed if it is desirable to have the altered content made visibly legible. Various other embodiments are disclosed. | 08-26-2010 |
20110023740 | Offset Printing Process Using Light Controlled Wettability - A lithographic printing method including exposing an imaging surface layer of a printing plate to a first expose source to render the surface layer uniformly hydrophilic; the surface layer comprising a compound having reversible light controlled wettability whereby the surface layer is reversibly hydrophilic and hydrophobic. The surface layer is disposed over a variable image portion of the printing plate imaging surface or disposed over substantially all of the printing plate imaging surface. The surface is exposed to a second expose source to render image areas of the surface layer hydrophobic. Polar liquid attracts to non-image hydrophilic areas. Hydrophobic liquid colorant attracts to hydrophobic image areas. The surface layer is contacted an offset receiving member and the image is transferred to an image receiving substrate. | 02-03-2011 |
20110026050 | Laser Printing Process Using Light Controlled Wettability - A light controlled laser imaging method includes exposing a surface layer of an imaging member substrate to a first expose source to render the surface layer uniformly hydrophilic, wherein the surface layer comprises a compound having reversible light controlled wettability whereby the surface layer is reversibly hydrophilic and hydrophobic; exposing the surface layer to a second expose source in an image-wise fashion to render image areas of the surface layer hydrophobic; exposing the surface layer to a polar liquid wherein the polar liquid attracts to non-image hydrophilic areas; exposing the surface layer to a hydrophobic liquid colorant wherein the hydrophobic liquid colorant attracts to hydrophobic image areas; contacting the surface layer with an image receiving substrate to transfer the image thereto; fixing the image; and optionally, treating the surface layer to remove residual hydrophobic liquid colorant. | 02-03-2011 |
20110187037 | SAWTOOTH JOG FOR MULTI-COPY/MULTI-SET OUTPUT - A method of positioning copy or subsets for the easy insertion of tabs thereinto that includes creating a shingled boundary between subsets, with the top sheets of all subsets in the same position, but with the rest of each subset progressively offset so that the last page of the upper subset is significantly offset from the top sheet of the next subset in sawtooth fashion. As a result, the subsets can then be separated from one side more easily and tabs or other pages can be manually inserted with minimal difficulty. | 08-04-2011 |
20120150705 | VIRTUAL ELECTRONIC PAYMASTER METHOD AND SYSTEM - A virtual electronic paymaster system and method for processing a paycheck utilizing a multi-function device. A virtual paymaster application can be configured in association with an EIP (Extensible Interface Platform) enabled multi-function device in order to render the paycheck with respect to an employee. An identification card having a bar code can be placed on a platen of the multi-function device in order to obtain authentication data with respect to the employee upon providing a PIN number via a user interface. The authentication data can be further provided to a remote application server via a network in order to retrieve the payment information with respect to the employee from a payroll database. The paycheck can be locally rendered based on the rendering instructions from the remote application server thereby enhancing the payroll processing within a business environment. | 06-14-2012 |
Patent application number | Description | Published |
20110242583 | In-Line System for the Validation of a Page Description Language within a Print Data Stream - The present specification discloses a printer in which the printer performs a first analysis of a print job data to identify a page description language and if no page description language is identified by the first analysis, performs additional processing activities, including but not limited to spooling and parsing, concurrent to a second analysis of the entire print job data to identify a page description language. | 10-06-2011 |
20110261390 | SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT FOR IMPLEMENTING A PRINT SERVICES NETWORK - Disclosed are embodiments of a system, method and computer program product for implementing a federated print services network. The embodiments provide a central server that receives external print job requests from customers and, optionally, any backlog of internal print job requests from a participating print shop or any internal print job requests that are outside a participating print shop's current printing capabilities or that exceed the participating print shop's supply inventory. The server can selectively distribute those requests amongst the participating print shops in the network for fulfillment. Distribution is based on printing equipment utilization records in order to balance printing equipment utilization across the network and, if necessary, on printing capability records and/or supply inventory records. Thus, for participating print shops, the embodiments provide a means for increasing equipment utilization percentages during downtimes and, thereby a means to subsidize the cost of ownership. They also provide a means for abating any backlog of print job requests and fulfilling, as necessary, any internal print job requests. | 10-27-2011 |
20110266739 | SAWTOOTH JOG FOR MULTI-COPY/MULTI-SET OUTPUT - A method of positioning copy or subsets for the easy insertion of tabs thereinto that includes creating a shingled boundary between subsets, with the top sheets of all subsets in the same position, but with the rest of each subset progressively offset so that the last page of the upper subset is significantly offset from the top sheet of the next subset in sawtooth fashion. As a result, the subsets can then be separated from one side more easily and tabs or other pages can be manually inserted with minimal difficulty. | 11-03-2011 |
20120206772 | OPTIMAL CONTRAST LEVEL DRAFT-MODE PRINTING USING SPATIAL FREQUENCY ANALYSIS - Devices and methods herein receive a command into a computerized device to perform a printing draft operation of a printable item using a reduced amount of marking material (a reduced amount of ink, toner, etc.). The methods herein evaluate at least two different regions of the printable item to determine spatial frequencies of the different regions, and calculate at least two marking material reduction values for the different regions of the printable item based on the spatial frequencies of the different regions. Then, the methods herein apply the marking material reduction values to the printable item to produce a file containing reduced marking material printing commands for a printing device to print the printable item. | 08-16-2012 |
20140035603 | Printed Stretch Sensor - Disclosed is a patterned article comprising: (1) a deformable nonconductive substrate; (2) an imagewise pattern thereon of a conductive stretchable ink; and (3) an external circuit connecting the imagewise pattern, the external circuit being capable of measuring the electrical resistance across regions of the deformable nonconductive substrate and determining the degree of deformation thereof. | 02-06-2014 |
Patent application number | Description | Published |
20120113449 | MOBILE DEVICE SCAN FOR PRINTING DEVICES - Methods and systems provide a user with an option, on a graphic user interface of a printing device, for scanning a self-illuminated display of a portable device (such as a cell phone, PDA, camera, etc.). In response to the user selecting the option for scanning a self-illuminated display of their portable device, the illumination source of the printing device is deactivated and the responsiveness of the light sensor of the printing device is increased. The process of increasing of the responsiveness of the light sensor changes the responsiveness to an increased level above a base level that is used when the illumination source is active. Then, while the illumination source is deactivated and while the responsiveness of the light sensor is at the increased level, the light sensor is used to scan the self-illuminated display of the portable device to acquire an image displayed on the self-illuminated display of the portable device. | 05-10-2012 |
20130117298 | WEB SERVICE PERFORMANCE OPTIMIZATION BY ADAPTIVELY USING COMPRESSION - A method, non-transitory computer readable medium and apparatus for optimizing a web service by adaptively using compression are disclosed. For example, the method receives a request for a data file, determines whether the data file should be compressed based upon a previous request for the data file, compresses the data file if it is determined that the data file should be compressed, and sends the data file in a compressed format. | 05-09-2013 |
20130266256 | OPTICAL SWITCH - Aspects of the disclosure include an optical button, that can include an input portion that is printed on a substrate, the input portion being configured to change an optical characteristic of light passing therethrough when in contact with an external object, and a detector that is optically coupled with the input portion to detect a change in the optical characteristic of light passing through the input portion. | 10-10-2013 |
20140028866 | METHOD AND APPARATUS FOR REMOTELY CONTROLLING A CAMERA CONNECTED TO A MULTI-FUNCTION DEVICE - A method, non-transitory computer readable medium, and apparatus for remotely controlling a camera connected to a multi-function device are disclosed. For example, the method receives a request from a third party server to instruct the camera to take a photograph, sends a call to the camera to take the photograph, wherein the call is sent to the camera over a universal serial bus (USB) connection between the multi-function device and the camera, receives the photograph and transmits the photograph to the third party server. | 01-30-2014 |
Patent application number | Description | Published |
20080287807 | GLOBAL MOTION INVARIANT SIGNATURES FOR FAST AND ACCURATE MOTION TRACKING IN A DIGITAL IMAGE-BASED ELASTO-TOMOGRAPHY SYSTEM - A method for converting digital images of an actuated breast into an accurate description of breast surface motion from a digital image-based elasto-tomography system comprises the steps of artificially placing a high density of fiducial markers on the breast surface, whereby the fiducial markers have different qualities and are placed in different proportions according to their quality; utilizing motion invariant properties of the fiducial markers to form a global motion invariant signature; tracking the markers on the actuated breast surface from image to image in each digital camera using the global motion invariant signature; and using the cameras calibration to measure the breast surface motion. | 11-20-2008 |
20090041327 | LINEAR STRUCTURE VERIFICATION IN MEDICAL APPLICATIONS - A method is disclosed for verifying linear structures in a digital mammographic image, comprising providing a configurable linear structure verifier in mammography computer assisted diagnosis system; optionally using an microcalcification candidate cluster driven linear structure verification methodology; selecting parameters for the linear structure verifier from a plurality of different parameter generating sources, at least one of which is controllable by human input; configuring the verifier according to selected parameters; and verifying linear structure using cascade rules. | 02-12-2009 |
20090216131 | USE OF SURFACE MOTION TO IDENTIFY MECHANICAL PROPERTIES OF BIOLOGICAL TISSUE - A method and apparatus to obtain information about the mechanical properties of a biological tissue by inducing periodic motion in the tissue, imaging the surface motion of the tissue under induced motion, processing the imaged surface motion to obtain descriptive metrics about the surface motion and relating one or more of these descriptive metrics to obtain information about the mechanical properties of the tissue. | 08-27-2009 |
20110208043 | GLOBAL MOTION INVARIANT SIGNATURES FOR FAST AND ACCURATE MOTION TRACKING IN A DIGITAL IMAGE-BASED ELASTO-TOMOGRAPHY SYSTEM - A method for converting digital images of an actuated breast into an accurate description of breast surface motion from a digital image-based elasto-tomography system comprises the steps of artificially placing a high density of fiducial markers on the breast surface, whereby the fiducial markers have different qualities and are placed in different proportions according to their quality; utilizing motion invariant properties of the fiducial markers to form a global motion invariant signature; tracking the markers on the actuated breast surface from image to image in each digital camera using the global motion invariant signature; and using the cameras calibration to measure the breast surface motion. | 08-25-2011 |
Patent application number | Description | Published |
20130099582 | POWER SYSTEM STABILIZATION - A method of damping power system oscillations includes obtaining an AC measurement signal from a power system location and determining oscillation frequency values in the AC measurement signal. A plurality of single signal components are extracted from the AC measurement signal by subtracting a plurality of processed measurement signals from the AC measurement signal and a damping signal is generated based on the plurality of single signal components. Each of the plurality of processed measurement signals are generated by time delaying the AC measurement signal with a time delay associated with each of the oscillation frequency values other than the oscillation frequency value of the single signal component to be extracted. | 04-25-2013 |
20130107407 | SYSTEM FOR ELECTRIC DISTRIBUTION SYSTEM PROTECTION AND CONTROL AND METHOD OF ASSEMBLING THE SAME | 05-02-2013 |
20130138366 | ELECTRIC DISTRIBUTION SYSTEM PROTECTION - A system for distributing electrical current to a plurality of loads includes a first sensor coupled to an input of a protection zone for measuring a first current entering the protection zone, wherein the protection zone includes at least a portion of an electrical distribution feeder. The system also includes a second sensor coupled to an output of the protection zone for measuring a second current exiting the protection zone, and a processor coupled to the first sensor and to the second sensor. The processor is programmed to receive measurements representative of the first current and the second current, and calculate a reactive current differential of the protection zone based on the first current and the second current. The processor is also programmed to compare the reactive current differential with a fault threshold, and generate an error notification if the reactive current differential is greater than the fault threshold. | 05-30-2013 |
20130197705 | POWER SYSTEM STABILIZATION - A method of damping power system oscillations include obtaining a time synchronized damping control signal from a remote location and determining a communication time delay in receiving the time synchronized damping control signal from the remote location. The time synchronized damping control signal is then modified based on a phase compensation factor and an amplitude compensation factor determined from the time delay. Finally, a damping signal is generated based on the modified time synchronized damping control signal. | 08-01-2013 |