Sawchuk
Blaine Sawchuk, Calgary CA
Patent application number | Description | Published |
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20140208868 | METERING TUBES FOR IMPROVED FLUID FLOW MEASUREMENT - A meter tube assembly for use with an ultrasonic flow meter is provided. The meter tube assembly includes a pipe spool having an extremely rough first section including an interior surface with a relative roughness (ε/D) of 1% or greater. Fluid passing through the extremely rough section exhibits a flow profile that remains substantially constant over the range of Reynolds numbers. As such, ultrasonic flow meters can be simplified as they need not account for different Reynolds numbers. | 07-31-2014 |
Blaine D. Sawchuk, De Winton CA
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20120247223 | Electroless Plated Fluid Flow Conditioner and Pipe Assembly - A method and system for electroless nickel plating of fluid flow measurement components used in oil and gas pipelines provides uniformly and consistently plating of all surfaces of the fluid flow components, including flow conditioners, with an electroless nickel plating that imparts the component with desirable characteristics related to hardness, smoothness, wear and abrasion resistance, and corrosion and oxidation resistance, such that the build up of contaminant deposits on the component is reduced and repeatable and accurately fluid flow measurements can be made. | 10-04-2012 |
Dale P. Sawchuk, Calgary CA
Patent application number | Description | Published |
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20120247223 | Electroless Plated Fluid Flow Conditioner and Pipe Assembly - A method and system for electroless nickel plating of fluid flow measurement components used in oil and gas pipelines provides uniformly and consistently plating of all surfaces of the fluid flow components, including flow conditioners, with an electroless nickel plating that imparts the component with desirable characteristics related to hardness, smoothness, wear and abrasion resistance, and corrosion and oxidation resistance, such that the build up of contaminant deposits on the component is reduced and repeatable and accurately fluid flow measurements can be made. | 10-04-2012 |
Daniel Sawchuk, Chestermere CA
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20150240843 | FLOW CONDITIONER WITH INTEGRAL VANES - A flow conditioner includes a single disk comprising an array of holes and at least one integral vane, for example a plurality of integral vanes. The at least one integral vane is machined out of the same material as the flow conditioner and is not attached to the flow conditioner via a weld connection or adhesive. | 08-27-2015 |
20150316084 | Flow Conditioner with Integral Vanes - A flow conditioner includes a single disk comprising an array of holes; a first set of integral vanes at least partially following a contour or pattern of an outer ring the holes; and a second set of integral vanes at least partially following a contour or pattern of an inner ring the holes. The second set of integral vanes is recessed from the first set of integral vanes in a stepped configuration. | 11-05-2015 |
20160097411 | FLOW CONDITIONER AND METHOD OF DESIGNING SAME - A flow conditioner includes a single disk having a first side and a second side; an outer ring comprising a plurality of holes, wherein the holes extend from the outer ring to the first side of said disk; at least one inner ring recessed from the outer ring, said at least one inner ring comprising a plurality of holes, wherein the holes extend from the at least one inner ring to the first side of said disk; and a central hole recessed from the at least one inner ring. The plurality of holes in the outer ring and in the at least one inner ring provide fluid passages of unequal length from a first side of the flow conditioner to a second side of the flow conditioner. | 04-07-2016 |
Daniel A. Sawchuk, Calgary CA
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20150328492 | Gloves For Adjusting and Controlling Resistance to Hand Movement, And Related Methods Thereof - A glove having a top surface and a bottom surface is described herein. The top surface and the bottom surface each have an inner surface and an outer surface. The glove includes a plurality of resistance bands, which can be configured to be removably attached to the glove. The resistance bands can be removably attached at connection points on the outer surface of the glove. The glove can also include at least one adjustable resistance mechanism connected to the glove. The adjustable resistance mechanism is configured to adjust degrees of resistance to motion via the resistance bands. | 11-19-2015 |
Daniel A. Sawchuk, Chestermere CA
Patent application number | Description | Published |
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20120247223 | Electroless Plated Fluid Flow Conditioner and Pipe Assembly - A method and system for electroless nickel plating of fluid flow measurement components used in oil and gas pipelines provides uniformly and consistently plating of all surfaces of the fluid flow components, including flow conditioners, with an electroless nickel plating that imparts the component with desirable characteristics related to hardness, smoothness, wear and abrasion resistance, and corrosion and oxidation resistance, such that the build up of contaminant deposits on the component is reduced and repeatable and accurately fluid flow measurements can be made. | 10-04-2012 |
20130306183 | Reflector For Fluid Measurement System - A reflector for a fluid flow system includes an orifice plate comprising a flange and an opening; at least one disk; and at least one vane extending between the orifice plate and the at least one disk. | 11-21-2013 |
20140196535 | Extended Length Flow Conditioner - A flow conditioner includes 1) a single disk comprising an array of holes and having an outer ring of holes, and 2) a section extending longitudinally from an outer circumference of the disk and comprising bores that at least partially follow the contour or pattern of the outer ring of holes. | 07-17-2014 |
20160003416 | Systems and Methods for Generating Swirl in Pipelines - A system for generating swirl includes a pipe and at least two orifice plates located within a section of the pipe and defining a swirl generation area. Each orifice plate has an off-set orifice or hole and is configured to have a position that is adjustable within the swirl generation area. Each orifice plate may be oriented at an angle variable to each other to generate a variable degree of swirl as fluid flow exits the swirl generation area. | 01-07-2016 |
20160061372 | Heated Flow Conditioning Systems And Methods of Using Same - A heated flow conditioning system includes a flow conditioner comprising a plurality of apertures and a flange, the flange surrounding said plurality of holes and comprising a first open-ended groove; and a spacer ring comprising a second open-ended groove. The first and the second open-ended grooves are configured to be connectable to each other, thereby forming a fluid channel for at least one heating medium. | 03-03-2016 |
Dennis Sawchuk, Hoboken, NJ US
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20080220432 | Optimized host cells for protein production - The present invention relates to methods for isolating cells that express increased levels of an RNA or protein of interest, wherein the cells exhibit altered growth profiles, such as cells with increased or decreased rates of proliferation, increased or decreased rates of apoptosis, or cells with a biphasic growth profile. | 09-11-2008 |
20100298167 | NOVEL CELL LINES EXPRESSING ENAC AND METHODS USING THEM - Cell lines that stably express ENaC and methods for using those cell lines are disclosed herein. The invention includes cell lines that express various subunit combinations and various proteolyzed isoforms of ENaC and techniques for creating cell lines. The ENaC-expressing cell lines are highly sensitive, physiologically relevant and produce consistent results. | 11-25-2010 |
Dennis Sawchuk, Fanwood, NJ US
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20120015841 | NOVEL CELL LINES AND METHODS - The invention relates to novel cells and cell lines, and methods for making and using them. | 01-19-2012 |
Dennis J. Sawchuk, Fanwood, NJ US
Patent application number | Description | Published |
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20120058918 | CELL LINES EXPRESSING CFTR AND METHODS OF USING THEM - Disclosed herein are cells and cell lines that stably express CFTR and methods for using those cells and cell lines. The invention also includes techniques for creating these cells and cell lines. The cells and cell lines of this invention are physiologically relevant. They are highly sensitive and provide consistent and reliable results in cell-based assays. | 03-08-2012 |
20120276572 | METHODS AND COMPOSITIONS FOR IDENTIFYING AND VALIDATING MODULATORS OF CELL FATE - The invention provides for compositions and methods for identifying and validating modulators of cell fate, such as such as maintenance, cell specification, cell determination, induction of stem cell fate, cell differentiation, cell dedifferentiation, and cell trans-differentiation. The invention relates to reporter nucleic acid constructs, host cells comprising such constructs, and methods using such cells and constructs. The invention relates to methods for making cells comprising one or more reporter nucleic acid constructs using fluorogenic oligonucleotides. The methods relate to high throughput screens. | 11-01-2012 |
20150141289 | Methods and Compositions for Identifying and Validating Modulators of Cell Fate - The invention provides for compositions and methods for identifying and validating modulators of cell fate, such as such as maintenance, cell specification, cell determination, induction of stem cell fate, cell differentiation, cell dedifferentiation, and cell trans-differentiation. The invention relates to reporter nucleic acid constructs, host cells comprising such constructs, and methods using such cells and constructs. The invention relates to methods for making cells comprising one or more reporter nucleic acid constructs using fluorogenic oligonucleotides. The methods relate to high throughput screens. | 05-21-2015 |
20150299782 | METHODS AND MATERIALS USING SIGNALING PROBES - Methods of isolating cells or generating cell lines comprising the step of exposing the cells to signaling probes that produce a signal upon hybridization to a target sequence, as well as methods of quantifying the level of expression of an RNA of interest, methods for identifying genetic recombinational events in living cells and methods of generating a transgenic animal using the isolated cells. Methods for isolating a plurality of cells encoding a plurality of different RNAs associated with a same nucleic acid tag sequence, comprising the step of exposing the cells to a same signaling probe that produces a detectable signal upon hybridization to the same nucleic acid tag sequence, are also provided. Signaling probes and protease probes that form stem-loop structures, three-arm junction structures, and dumbbell structures may be used in the above methods. | 10-22-2015 |
20150315554 | CELL LINES EXPRESSING CFTR AND METHODS OF USING THEM - Disclosed herein are cells and cell lines that stably express CFTR and methods for using those cells and cell lines. The invention also includes techniques for creating these cells and cell lines. The cells and cell lines of this invention are physiologically relevant. They are highly sensitive and provide consistent and reliable results in cell-based assays. | 11-05-2015 |
Dennis J. Sawchuk, Hoboken, NJ US
Patent application number | Description | Published |
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20090106853 | Methods and materials using signaling probes - The present invention relates to methods of isolating cells or generating cell lines using signaling probes that produce a signal upon hybridization to a target sequence. Other methods that utilize the signaling probe include methods of quantifying the level of RNA expression, methods for identifying genetic recombinational events in living cells and methods of generating a transgenic animal using the isolated cells. The invention also provides protease probes. Signaling probes and protease probes that form stem-loop structures, three-arm junction structures, and dumbbell structures are provided. | 04-23-2009 |
Dennis James Sawchuk, Fanwood, NJ US
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20160123959 | METHODS AND MATERIALS USING SIGNALING PROBES - The present invention relates to methods of isolating cells, generating cell lines, and detecting RNAs in cells using signaling probes that produce a signal upon hybridization to a target sequence. Other methods that utilize the signaling probe include methods of detecting or quantifying the effect of an agent on RNAs in a cell, methods of quantifying the level of RNA expression, methods for identifying genetic recombinational events in living cells and methods of generating a transgenic animal using the isolated cells. The invention also provides protease probes. Signaling probes and protease probes that form stem-loop structures, three-arm junction structures, and dumbbell structures are provided. | 05-05-2016 |
Robert T. Sawchuk, Roseville, MN US
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20090299421 | EVALUATION OF IMPLANTABLE MEDICAL DEVICE SENSING INTEGRITY BASED ON EVOKED SIGNALS - The disclosure describes techniques for evaluating sensing integrity of an implantable medical device (IMD) based on sensing of evoked signals. Sensing integrity may provide an indication of reliability of implantable leads associated with an IMD. The sensed signals may be signals that are evoked by tissue in response to delivery of electrical stimulation. The techniques may involve evaluation of sensing integrity based on sensing of evoked cardiac potentials generated in response to cardiac stimulation, such as pacing pulses. Signals evoked in response to electrical stimulation may be measured and trended to permit analysis of evoked signals over time. Lead integrity may be inferred from sensing integrity. By analyzing evoked signals, sensing integrity may be evaluated without sensing intrinsic events. Evaluation of sensing integrity can facilitate analysis in the presence of pacing, including pacing delivered by IMDs that pace substantially continuously, such as IMDs configured to support cardiac resynchronization therapy (CRT). | 12-03-2009 |
20100198292 | EVALUATING ELECTRODE CONFIGURATIONS FOR DELIVERING CARDIAC PACING THERAPY - Described techniques include delivering cardiac pacing therapy from a medical device to a chamber of a heart via a first electrode configuration and determining that the delivery of cardiac pacing therapy via the first electrode configuration inadequately captures the chamber. In response to such a determination, the medical device delivers cardiac pacing therapy to the chamber of the heart via a plurality of additional electrode configurations. The techniques further comprise determining a capture characteristic for each of the additional electrode configurations based on the delivery of cardiac pacing therapy to the chamber of the heart via the plurality of other electrode configurations. A new electrode configuration for cardiac pacing may be selected based on the capture characteristics of the various electrode configurations. | 08-05-2010 |
Ronald J. Sawchuk, Prior Lake, MN US
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20120289541 | METHODS AND COMPOSITIONS FOR APPLYING MOXIFLOXACIN TO THE EAR - Methods and materials useful for applying moxifloxacin to the ear are described. The methods involve delivering a composition that contains at least one viscogenic agent and moxifloxacin or a salt thereof to the epidermal surface of the tympanic membrane via the ear canal. The composition is delivered to the tympanic membrane in a flowable form and, after delivery to the tympanic membrane, becomes sufficiently viscous such that the moxifloxacin is localized against the tympanic membrane. Such compositions can be used to prophylactically and/or therapeutically treat middle and inner ear conditions, including otitis media. | 11-15-2012 |
20140364383 | METHODS AND COMPOSITIONS FOR APPLYING PHARMACOLOGIC AGENTS TO THE EAR - Methods and materials useful for applying pharmacologic agents to the ear are described. The methods involve delivering a composition that contains at least one viscogenic agent and at least one pharmacologic agent to the epidermal surface of the tympanic membrane via the ear canal. The composition is delivered to the tympanic membrane in a flowable form and, after delivery to the tympanic membrane, becomes sufficiently viscous such that the pharmacologic agent is localized against the tympanic membrane. Such compositions can be used to prophylactically and/or therapeutically treat middle and inner ear conditions, including otitis media. | 12-11-2014 |