Anatol
Anatol Kontush, Paris FR
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20100179066 | Method for Assessing the Risk of a Cardiovascular Disease and for Diagnosing Dyslipidemia - The invention relates to a method for assessing the risk of a cardiovascular disease and/or for diagnosing dyslipidemia in a patient, said method comprising: a) isolating in a blood sample obtained from said patient the high density lipoprotein (HDL) fraction or a subfraction thereof; and b) measuring in said HDL fraction or subfraction thereof the concentration of one or more biomarkers selected from the group consisting of Sphingosine-1-Phosphate (S1P), sphingomyelin (SM) and Apolipoprotein A-I (apoA-1). | 07-15-2010 |
Anatol Koutychenko, Moscow RU
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20090137779 | Peptide inhibitors of thrombin as potent anticoagulants - The tetrapeptide Phe-Asn-Pro-Arg (SEQ ID NO: 3) is a structurally-optimized sequence for binding to the active site of thrombin. By conjugating this tetrapeptide or variants thereof to a C-terminal fragment of hirudin, we were able to generate a series of new multivalent inhibitors of thrombin containing only genetically encodable natural amino acids. We found that synergistic binding to both the active site and an exosite of thrombin can be enhanced through substitutions of amino acid residues at the P | 05-28-2009 |
Anatol Krozer, Goteborg SE
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20090085557 | DETECTION DEVICE AND METHOD - The present invention relates to method and device for detecting changes of a magnetic response of at least one magnetic particle in a carrier fluid. The method comprises: using a measuring procedure comprising measuring the characteristic rotation time of said magnetic particle, said measuring procedure further involving measuring Brownian relaxation in said carrier fluid under influence of an external pulsed excitation magnetic field, and based on said influence of said external pulsed excitation magnetic field measuring a hydrodynamic volume of a particle or a change in a hydrodynamic volume of the particle change upon modification of an effective volume of the particle or its interaction with said carrier fluid by detecting change of magnetization of the particle with time by monitoring change of an output signal in detection coil. | 04-02-2009 |
20120045838 | CUSTOMIZED MOLECULARLY IMPRINTED POLYMER (MIP) UNITS - A method of manufacturing at least one customized MIP unit including: (a) providing at least one MIP unit having a surface including at least one target binding site configured to resemble a target molecule and surface-bound chargeable groups; (b) contacting the MIP unit(s) from the step (a) with at least one template molecule in a first solvent allowing the template molecule(s) to bind to the MIP unit(s); (c) passivating the surface-bound chargeable groups on the MIP unit(s) by adding a passivating agent; and (d) removing the template molecule(s) by washing in a second solvent, wherein the passivating agent binds to the surface of the unit(s) through bonds which remain stable upon washing in the second solvent. | 02-23-2012 |
20130206359 | HEAT EXCHANGER PLATE AND A PLATE HEAT EXCHANGER - The invention refers to a plate heat exchanger and a heat exchanger plate. The heat exchanger plate for a plate comprises a heat transfer area and an edge area, extending around the heat transfer area. The heat exchanger plate is a double wall plate formed by two adjoining plates compressed to be in contact with each other. The heat exchanger plate comprises a sensor which is configured to sense at least one parameter and to produce a signal depending on the parameter and that the sensor comprises a sensor probe that is provided between the adjoining plates. | 08-15-2013 |
Anatol Krozer, Gothenburg SE
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20130189159 | METHOD OF MODIFYING THE PROPERTIES OF A SURFACE - The present invention relates to a method, comprising: coating a surface with a mussel adhesive protein such that a first layer comprising the MAP is achieved on the first surface, and providing a second layer comprising a first plurality of particles on at least a portion of said first layer comprising said MAP. It also relates to a device comprising a substrate having a first surface; a first layer comprising said MAP, said first layer being arranged on said first surface, and a second layer comprising a first plurality of particles attached to at least a portion of said MAP of said first layer. The present invention is based on the realization that a MAP can advantageously be used to immobilize particles on a substrate, for example in a layer-by-layer assembly. Thereby, providing a highly functionalized surface. | 07-25-2013 |
Anatol Kwartler, Silver Lake, OH US
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20140259986 | SLIDING LOCKING ACTUATOR FOR AUTOMATIC TILT MECHANISM - A mast assembly including a locking actuator for locking a cradle of the mast in position. The locking actuator includes a housing having a first lock pin extending in a first direction and a movable member supported by the housing having a second lock pin extending in a second direction opposite the first, the locking actuator being slideably mounted to the cradle for sliding movement along an axis parallel to an axis of extension/retraction of the locking actuator. When the locking actuator is extended the first and second lock pins are inserted into respective lock holes in a base member thereby locking the cradle against pivoting movement relative to the base member. | 09-18-2014 |
20150050070 | TOGGLE LATCH FOR SEQUENTIALLY EXTENDED MECHANICAL MAST - An automatic locking system is provided that is driven by the normal extension and retraction of the mast, reduces the inherent rotation and deflection of the mast due to clearances, and operates more smoothly and quietly than conventional locking systems. The locking system also fits reasonably within the existing footprint of a typical mechanical mast. | 02-19-2015 |
Anatol Ryzhevich, Minsk BY
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20130099108 | CONTROLLING MICROPARTICLES THROUGH A LIGHT FIELD HAVING CONTROLLABLE INTENSITY AND PERIODICITY OF MAXIMA THEREOF - A method includes providing a capability to control divergence of a coherent light beam having an axially symmetrical distribution of intensity thereof through an optical divergence controller, and directing an output of the optical divergence controller related to the controlled divergence of the coherent light beam onto a glass prism. The glass prism includes a planar shape onto which a pyramidal structure is formed. The method also includes controlling a distance between maxima of an output light field of the glass prism and intensity thereof through controlling the divergence of the coherent light beam through the optical divergence controller and/or varying a distance between the optical divergence controller and the glass prism, and utilizing the output light field of the glass prism in controlling microparticles in a microtechnology or a nanotechnology application. | 04-25-2013 |