Rebecca
Rebecca Aft, Chesterfield, MO US
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20100048614 | THERAPEUTIC USES OF BICYCLIC LIGANDS OF SIGMA 2 RECEPTOR - A series of N-substituted 9-azabicyclo[3.3.1]nonan-3α-yl phenylcarbamate analogs are disclosed, as well as methods of their preparation. Their affinities for sigma (σ1 and σ2) receptors are described. Two new compounds, N-(9-(4-aminobutyl)-9-azabicyclo[3.3.1]nonan-3α-yl)-N′-(2-methoxy-5-methylphenyl)carbamate and N-(9-(6-aminohexyl)-9-azabicyclo[3.3.1]nonan-3α-yl)-N′-(2-methoxy-5-methylphenyl)carbamate, are shown to have a high affinity and selectivity for σ2 versus σ1 receptors. Among the disclosed compounds are biotinylated and fluorescent analogs. These compounds can serve as probes to the σ2 receptor. In addition, some disclosed compounds can induce apoptotic cell death by both caspase-dependent and caspase-independent mechanisms, and are effective for treatment of tumors. The compounds can be used as chemotherapeutics or chemosensitizers in the treatment of a wide variety of solid tumors. | 02-25-2010 |
Rebecca Bellone, Plant City, FL US
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20110104687 | Methods and Kits for Detecting Congenital Stationary Night Blindness and Selecting Different Coat Patterns - The present application describes biomarkers and methods useful for screening for, diagnosing or detecting congenital stationary night blindness in a subject. The present application also provides methods for selecting or detecting horse coat patterns. | 05-05-2011 |
Rebecca Bellone, Valrico, FL US
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20120145092 | Identification of the causative mutation for leopard complex spotting & congenital stationary night blindness in equines and a method for testing for same - Methods are provided for determining whether or not a horse is genetically normal, is a carrier of, or is affected with or predisposed to Congenital Stationary Night Blindness and/or leopard complex spotting. The method is based on detection of an insertion in an intron in the horse Transient Receptor Potential Cation Channel, Subfamily M, Member 1 (TRPM1) gene. | 06-14-2012 |
Rebecca Berrigan, Newark, CA US
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20090048417 | Biodegradable Shower Mat - A biodegradable shower mat has been disclosed. | 02-19-2009 |
Rebecca Braslau, Santa Cruz, CA US
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20110171677 | FLUORESCENCE DETECTION OF POISON OAK OIL - The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to bind to and/or deactivate a poison oak oil, such as urushiol. The compositions and methods can be used to treat and/or reduce an inflammatory reaction and/or hypersensitivity to natural compounds found in poison oak, poison ivy, poison sumac, mango, lac tree, and cashew nut. | 07-14-2011 |
20130121924 | FLUORESCENCE DETECTION OF POISON OAK OIL - The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to bind to and/or deactivate a poison oak oil, such as urushiol. The compositions and methods can be used to treat and/or reduce an inflammatory reaction and/or hypersensitivity to natural compounds found in poison oak, poison ivy, poison sumac, mango, lac tree, and cashew nut. | 05-16-2013 |
20140242712 | FLUORESCENCE DETECTION OF POISON OAK OIL - The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to bind to and/or deactivate a poison oak oil, such as urushiol. The compositions and methods can be used to treat and/or reduce an inflammatory reaction and/or hypersensitivity to natural compounds found in poison oak, poison ivy, poison sumac, mango, lac tree, and cashew nut. | 08-28-2014 |
Rebecca Breitenkamp, Amherst, MA US
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20090110662 | MODIFICATION OF BIOLOGICAL TARGETING GROUPS FOR THE TREATMENT OF CANCER - The present invention relates to the field of polymer chemistry and more particularly to click-functionalized targeting compounds and methods for using the same. | 04-30-2009 |
Rebecca Breitenkamp, Tampa, FL US
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20120046757 | COVALENT MODIFICATION OF METAL SURFACES - The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials. | 02-23-2012 |
20130310912 | COVALENT MODIFICATION OF METAL SURFACES - The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials. | 11-21-2013 |
Rebecca Breitenkamp, San Diego, CA US
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20100159020 | POLYMERIC MICELLES FOR DRUG DELIVERY - The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. | 06-24-2010 |
20110091534 | COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY - The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. | 04-21-2011 |
20110092668 | AZIDE FUNCTIONALIZED PEPTIDE TARGETING GROUPS - The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. | 04-21-2011 |
Rebecca Brumer, Arlington, MA US
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20090303001 | SYSTEM FOR DETECTING AND COMMUNICATING WITH RFID MEMORY DEVICES - This invention relates to a system of communicating with a radio frequency identification (RFID) transponder microchip (IC) for the purpose of accessing pre-programmed data. Such system involves direct electrical contact between the system reading the data from the memory in the transponder IC and the IC itself via two mechanical contact points. This system provides an interface with a transponder IC in order to energize the IC. Once the presence of the transponder IC is detected, the host system can read or write to and process preprogrammed data stored in the IC. | 12-10-2009 |
20100022864 | SKIN PREPARATION DEVICE AND BIOPOTENTIAL SENSOR - The skin preparation device and sensor of the present invention include an array of rigid tines. The tines serve to “self-prepare” the skin at each electrode site. These tines, when pressed against the skin, penetrate the stratum corneum, thereby reducing skin impedance and improving signal quality. A self-prepping device of the present invention is an optimized array of short non-conductive rigid tines in which the individual tines are created in a geometry that allows for a sharp point at the tip when molding, machining or etching is used as a method of fabrication. This non-conductive array with rigid penetrating structures may, therefore, be used in combination with a conductive medium, preferably an ionic conductive gel. In penetrating the stratum corneum, micro-conduits are created in the layers of the skin enabling the conductive medium to reach the low impedance layers and to transmit bioelectrical signals from the skin to the electrode surface. Such a self-prepping device can be readily mass produced using molding methods or possibly other manufacturing methods, thereby providing for a low cost means of achieving improved performance of the biopotential sensor. Additionally this invention includes the integration of this self-prepping device into a biopotential sensor comprising an array of one or more electrodes. | 01-28-2010 |
20110273270 | PHYSIOLOGICAL SENSOR SYSTEM WITH AUTOMATIC AUTHENTICATION AND VALIDATION BY MEANS OF A RADIO FREQUENCY IDENTIFICATION PROTOCOL WITH AN INTEGRATED RFID INTERROGATOR SYSTEM - This invention relates to a physiological sensor which acquires pre-programmed data from an electrode or an electrode array using Radio Frequency Identification (RFID) technology. The source of the sensor may be authenticated by means of a wireless interface between an RFID transponder affixed to the electrode array, and an RFID interrogator embedded in the patient interface cable. The criteria for use are then verified to ensure that they are met by the electrode array before beginning signal acquisition. If the criteria are not met, a message is provided to the user via the monitor. | 11-10-2011 |
20120098646 | PHYSIOLOGICAL SENSOR SYSTEM WITH AUTOMATIC AUTHENTICATION AND VALIDATION BY MEANS OF A RADIO FREQUENCY IDENTIFICATION PROTOCOL WITH AN INTEGRATED RFID INTERROGATOR SYSTEM - This invention relates to a physiological sensor which acquires pre-programmed data from an electrode or an electrode array using Radio Frequency Identification (RFID) technology. The source of the sensor may be authenticated by means of a wireless interface between an RFID transponder affixed to the electrode array, and an RFID interrogator embedded in the patient interface cable. The criteria for use are then verified to ensure that they are met by the electrode array before beginning signal acquisition. If the criteria are not met, a message is provided to the user via the monitor. | 04-26-2012 |
20130234830 | PHYSIOLOGICAL SENSOR SYSTEM WITH AUTOMATIC AUTHENTICATION AND VALIDATION BY MEANS OF A RADIO FREQUENCY IDENTIFICATION PROTOCOL WITH AN INTEGRATED RFID INTERROGATOR SYSTEM - This invention relates to a physiological sensor which acquires pre-programmed data from an electrode or an electrode array using Radio Frequency Identification (RFID) technology. The source of the sensor may be authenticated by means of a wireless interface between an RFID transponder affixed to the electrode array, and an RFID interrogator embedded in the patient interface cable. The criteria for use are then verified to ensure that they are met by the electrode array before beginning signal acquisition. If the criteria are not met, a message is provided to the user via the monitor. | 09-12-2013 |
20130293357 | METHOD FOR DETECTING AND COMMUNICATING WITH RFID MEMORY DEVICES - This invention relates to a system of communicating with a radio frequency identification (RFID) transponder microchip (IC) for the purpose of accessing pre-programmed data. Such system involves direct electrical contact between the system reading the data from the memory in the transponder IC and the IC itself via two mechanical contact points. This system provides an interface with a transponder IC in order to energize the IC. Once the presence of the transponder IC is detected, the host system can read or write to and process preprogrammed data stored in the IC. | 11-07-2013 |
20140159917 | PHYSIOLOGICAL SENSOR SYSTEM WITH AUTOMATIC AUTHENTICATION AND VALIDATION BY MEANS OF A RADIO FREQUENCY IDENTIFICATION PROTOCOL WITH AN INTEGRATED RFID INTERROGATOR SYSTEM - This invention relates to a physiological sensor which acquires pre-programmed data from an electrode or an electrode array using Radio Frequency Identification (RFID) technology. The source of the sensor may be authenticated by means of a wireless interface between an RFID transponder affixed to the electrode array, and an RFID interrogator embedded in the patient interface cable. The criteria for use are then verified to ensure that they are met by the electrode array before beginning signal acquisition. If the criteria are not met, a message is provided to the user via the monitor. | 06-12-2014 |
20140296683 | SKIN PREPARATION DEVICE AND BIOPOTENTIAL SENSOR - The skin preparation device and sensor of the present invention include an array of rigid tines. The tines serve to “self-prepare” the skin at each electrode site. These tines, when pressed against the skin, penetrate the stratum corneum, thereby reducing skin impedance and improving signal quality. A self-prepping device of the present invention is an optimized array of short non-conductive rigid tines in which the individual tines are created in a geometry that allows for a sharp point at the tip when molding, machining or etching is used as a method of fabrication. This non-conductive array with rigid penetrating structures may, therefore, be used in combination with a conductive medium, preferably an ionic conductive gel. In penetrating the stratum corneum, micro-conduits are created in the layers of the skin enabling the conductive medium to reach the low impedance layers and to transmit bioelectrical signals from the skin to the electrode surface. Such a self-prepping device can be readily mass produced using molding methods or possibly other manufacturing methods, thereby providing for a low cost means of achieving improved performance of the biopotential sensor. Additionally this invention includes the integration of this self-prepping device into a biopotential sensor comprising an array of one or more electrodes. | 10-02-2014 |
Rebecca Bularzik, North Andover, MA US
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20110256983 | VIRTUAL ANKLE AND BALANCE TRAINER SYSTEM - A rehabilitation system that combines robotics and interactive gaming to facilitate performance of task-specific, repetitive exercise to enable individuals undergoing rehabilitation to improve the performance of coordinated movements of the ankle, and to practice balance activities, is disclosed. More specifically, the rehabilitation system includes at least one two degree-of-freedom robotic, haptic interface for a mammalian foot and interactive gaming hardware that is coupled to a controller, to provide a virtual reality-like environment. | 10-20-2011 |
Rebecca Casaubon, Chestnut Hill, MA US
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20110201594 | PYRIDO [2,3-D] PYRIMIDINES AND THEIR USE AS KINASE INHIBITORS - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 08-18-2011 |
20140163003 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163004 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163005 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163006 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163007 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163222 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
20140163223 | Pyrido-[2,3-D] Pyrimidines and Their Use as Kinase Inhibitors - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 06-12-2014 |
Rebecca Casaubon, Cambridge, MA US
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20110257207 | RAF INHIBITORS - The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are inhibitors or kinases such as Raf, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer. | 10-20-2011 |
Rebecca Cavagnari, Scotts Valley, CA US
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20090019367 | APPARATUS, SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR COLLABORATION VIA ONE OR MORE NETWORKS - A collaboration architecture supports virtual meetings, including web conferencing and collaboration. Presence information is aggregated from different types of communication services to provide a generic representation of presence. In one implementation, collaboration lifecycle management is provided to manage meetings over the lifecycle of a project. Audio options include voice over internet protocol (VoIP) and conventional PTSN phone networks, which are supported in one implementation by an audio conferencing server. | 01-15-2009 |
Rebecca Chmielowski, Clark, NJ US
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20110144311 | METHODS FOR PURIFYING ANTIBODIES USING PROTEIN A AFFINITY CHROMATOGRAPHY - This invention provides a method for purifying a monomeric monoclonal antibody which comprises contacting the sample, wherein the sample comprises the monomeric monoclonal antibody, host cell impurities, dimers, and higher order aggregates, with a Protein A affinity chromatography column; eluting the monomeric monoclonal antibody from the Protein A affinity chromatography column with an elution buffer; and collecting one or more fractions of the monomeric monoclonal antibody to form a Protein A product pool, wherein the product pool comprises less than 5% higher order aggregate, and has a pH from about 3.2 to about 4.5, thereby purifying the monomeric monoclonal antibody from the sample. This invention also provides a method for purifying a monomeric monoclonal antibody which comprises eluting with acetate or citrate, optionally in the presence of amino acids. This invention also provides a method for purifying a monomeric monoclonal antibody which comprises conducting the method within certain temperature ranges. | 06-16-2011 |
Rebecca Craig-Schapiro US
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20110143380 | ALZHEIMER'S DISEASE BIOMARKERS AND METHODS OF USE - The invention encompasses biomarkers for AD, a method for detecting AD, a method of monitoring AD, and a kit for quantifying biomarkers for AD. | 06-16-2011 |
Rebecca Crallan, York GB
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20100297208 | SCAFFOLD - The present invention relates to scaffolds which can be used as medical devices for guided tissue regeneration and repair, in particular the invention is directed to a scaffold comprising fibres having a mean fibre diameter of between from about 1.2 to 4.0 microns, wherein the fibres comprise a glycolide. The invention further relates to the use of the scaffolds for the selective capture of cell populations for a cell source material. | 11-25-2010 |
Rebecca Croasdale, Penzberg DE
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20100081796 | BISPECIFIC ANTI-EGFR/ANTI-IGF-1R ANTIBODIES - The present invention relates to bispecific antibodies against EGFR and against IGF-1R, methods for their production, pharmaceutical compositions containing said antibodies, and methods of treatment using the antibodies. | 04-01-2010 |
20120149879 | BISPECIFIC ANTI-EGFR/ANTI-IGF-1R ANTIBODIES - The present invention relates to bispecific antibodies against EGFR and against IGF-1R, methods for their production, pharmaceutical compositions containing said antibodies, and methods of treatment using the antibodies. | 06-14-2012 |
Rebecca Croasdale, Antdorf DE
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20100322935 | Tri- or Tetraspecific Antibodies - The present invention relates to tri- or tetraspecific antibodies, their manufacture and use. | 12-23-2010 |
20110293613 | BISPECIFIC ANTIBODIES - The present invention relates to bispecific antibodies, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 12-01-2011 |
20120269723 | COMPLEX OF BI-SPECIFIC ANTIBODY AND DIGOXIGENIN CONJUGATED TO A THERAPEUTIC OR DIAGNOSTIC AGENT - The present invention relates to complexes of a) bi-specific antibodies and antibody fragments against a target protein and b) a digoxigenin conjugated to a therapeutic or diagnostic agent, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical compositions containing said antibodies, and uses thereof. | 10-25-2012 |
20120282280 | BI-SPECIFIC DIGOXIGENIN BINDING ANTIBODIES - This invention relates to bispecific antibodies and antibody fragments against a target protein and a hapten, wherein the hapten is PEG or biotin, most preferably digoxigenin, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical 5 compositions containing said antibodies, and uses thereof. | 11-08-2012 |
20130022601 | TRIVALENT, BISPECIFIC ANTIBODIES - The present invention relates to trivalent, bispecific antibodies, methods for their production, pharmaceutical compositions containing the antibodies, and uses thereof. | 01-24-2013 |
20130266568 | ACTIVATABLE BISPECIFIC ANTIBODIES - The current invention relates to bispecific antibodies wherein the binding affinity to one of the two antigens is reduced and which can be activated by tumor- or inflammation-specific proteases, and the preparation and use of such bispecific antibodies. | 10-10-2013 |
20150030598 | TRI- OR TETRASPECIFIC ANTIBODIES - The present invention relates to tri- or tetraspecific antibodies, their manufacture and use. | 01-29-2015 |
Rebecca Dee, Rowville AU
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20100331521 | Controlled Polymerisation Process - The present invention relates to a controlled metathesis-driven polymerisation process which is particularly useful for the synthesis of biological polymers such as peptides and polymers. The invention also provides metathesisable supports, groups and linkers for use in the process. | 12-30-2010 |
Rebecca Del Conte, Firenze IT
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20100047894 | Use of Matrix Metalloproteinases, Mutated and Not Mutated, for the Preparation of Pharmaceutical Compositions, and Mutated Metalloproteinases with Increased Stability - The use of matrix metalloproteinases, mutated and not mutated, for the preparation of pharmaceutical compositions useful in the treatment of pathologies associated with an accumulation of matrix bio-polymers and/or an excess of TIMPs (Tissue Inhihitors MetalloProteinases) is described; mutated matrix metalloproteinases, in which at least an aminoacid residue in a definite position in the protein, has been mutated into a hydrophilic and/or charged aminoacidic residue, obtaining an increased stability toward autoproteolysis are also described. | 02-25-2010 |
Rebecca Delegge, Mt. Pleasant, SC US
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20090082736 | Gastric access port - An improved mechanism for attaching a feeding tube to a feeding delivery system is presented. The feeding delivery system is attached to an elongated connecting member that is pivotally attached to a bolster. After attachment, the elongated connecting member is rotated to engage another tube at the base of the pivot. Before pivoting, the passageway is blocked by the interference of the elongated connecting member. As the elongated connecting member is rotated, the conduit system aligns and becomes a passageway to and from the stomach. The device provides a three part rigid plastic fit that does not wear out over a number of uses. The device prevents splash events, which occur when a feeding adapter is opened or when the adapter or valve is forced open by a cough or gastric pressure build up. | 03-26-2009 |
20090259189 | Catheter assembly including foldable internal bolster - A catheter assembly including a foldable internal bolster. According to one embodiment, the catheter assembly includes a catheter, a first flexible filament and a second flexible filament. The catheter includes a tubular body and a pair of flexible legs. The tubular body is a generally cylindrical member shaped to include a proximal end, a distal end, a longitudinal lumen, a pair of external notches, a first bore extending from the proximal end to one of the notches, and a second bore extending from the proximal end to the other of the notches. Each of the flexible legs has a fixed end and a free end, the fixed end being integrally formed on the distal end of the tubular body. One end of the first filament is fixed to one of the flexible legs, and the opposite end of the first filament is slidably inserted up through the first bore. One end of the second filament is fixed to the other of the flexible legs, and the opposite end of the second filament is slidably inserted up through the second bore. Consequently, by pulling the filaments up through their respective bores, the free ends of the legs may be drawn towards the tubular body to form a pair of loops suitable for use as an internal bolster. | 10-15-2009 |
20090306627 | UNIVERSAL PERCUTANEOUS ENDOSCOPIC GASTROSTOMY TUBE - A universal percutaneous endoscopic gastrostomy (PEG) tube that may be used with either the push or the pull insertion method. A loop extends from the tube. A void is formed in the tube at or near the proximal end of the tube. The void communicates with the internal void that acts as a conduit for material that is transported by the tube. The tube of the invention provides the option of changing technique from push method to pull method, or from pull method to push method. The device provides a mechanism at the tip or at mid catheter, thereby allowing for change over of method. | 12-10-2009 |
20120095405 | METHOD FOR IMPLANTING A PERCUTANEOUS ENDOSCOPIC GASTROSTOMY/JEJUNOSTOMY TUBE IN A PATIENT AND ACCESS NEEDLE FOR USE IN SAID METHOD - Method for implanting a percutaneous endoscopic jejunostomy tube in a patient and access needle for use in the method. In one embodiment, the method comprises the steps of (a) providing an access needle wherein the distal end of the stylet extends distally for an appreciable distance beyond the distal end of the cannula; (b) inserting the stylet, but not the cannula, into the jejunum; (c) grabbing the stylet with an endoscopically-positioned snare; (d) anchoring the jejunum against the abdominal wall using the snared stylet; (e) loosening the snare slightly while advancing the cannula into the jejunum and into the loosened snare; (f) tightening the snare around the cannula; (g) removing the stylet from the cannula; (h) inserting a guide wire or suture through the cannula into the jejunum; and (i) proceeding in the conventional fashion to implant a PEJ tube into the patient using the guide wire or suture. | 04-19-2012 |
20120197191 | ENTERAL FEEDING TUBE AND HOUSING - An enteral feeding tube provides a conduit for the flow of liquid nutritional material. Most of the enteral feeding tube that is external to the patient is generally horizontal when the device is positioned in a stoma of a user lying in a prostrate position. A housing surrounds the horizontal portion enteral feeding tube, provides a low profile, aids in holding the enteral feeding tube in place, and protects the enteral feeding tube. The bottom surface of the housing comprises a resilient material that contacts the skin of the patient. The enteral feeding tube comprises a balloon that is positioned in the stomach to retain the device in the stomach. An air conduit extends generally vertically from an upper portion of the housing and through the enteral feeding tube to communicate with the balloon. | 08-02-2012 |
20120283663 | Sheath for Protection of Medical Devices and Method of Use Thereof - A protective sheath for protecting elongated medical devices positioned in, or through, the sheath while performing a surgical procedure. The sheath is formed of a thin, flexible material that provides and maintains a clean and sterile and reliable path for medical instruments to travel within. The device provides a barrier between a medical instrument, the orifice/opening in which the instrument enters the human body, and the path these instruments travel to other body organs or locations, and reduces unwanted translocation. | 11-08-2012 |
Rebecca Deporte, Landenberg, PA US
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20100312699 | Debit purchasing of stored value card for use by and/or delivery to others - A method of issuing a purchase card is provided. The method includes the steps of presenting a purchaser with the opportunity to buy the purchase card, determining whether the purchaser has sufficient funds to pay for the purchase card, creating a purchase card account for a recipient designated by the purchaser, and issuing the purchase card. The purchase card may also be issued in connection with another credit card, for example as a rebate for purchases on the credit card. The purchase card may also be converted to a credit card. | 12-09-2010 |
Rebecca Emmons, Riehen CH
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20080287501 | THERAPEUTIC USES OF AN INSULIN SECRETION ENHANCER - The invention relates to the use of a hypolipidemic agent or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the prevention or delay of the progression to overt diabetes, especially type 2, prevention or reduction of microvascular complications (eg, retinopathy, neurophathy, nephropathy), prevention or reduction of excessive cardiovascular morbidity (eg, myocardial infarction, arterial occlusive disease, atherosclerosis and stroke) and cardiovascular mortality, prevention of cancer and reduction of cancer deaths. Additionally, the invention relates to the use of a treatment for diseases and conditions that are associated with IGM, IGT or IFG. | 11-20-2008 |
Rebecca Fiebrink, Princeton, NJ US
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20100194677 | MAPPING OF PHYSICAL CONTROLS FOR SURFACE COMPUTING - Physical controls on a physical controller device (PCD) are dynamically mapped to application controls for an application being executed on a computer having a touch-sensitive display surface. The computer identifies a PCD which has been placed by a user on the display surface and displays a mapping aura for the PCD. When the user touches an activate direct-touch button displayed within the mapping aura, the computer activates a mapping procedure for the PCD and displays a highlighted direct-touch button over each application control which is available to be mapped to the physical controls on the PCD. When the user selects a particular application control which is available to be mapped by touching the highlighted button residing over the control, the computer creates a dynamic mapping between the selected application control and a user-selected physical control on the PCD. | 08-05-2010 |
Rebecca Garcia, Greenwood, SC US
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20110008787 | DETECTION PRIMERS FOR NUCLEIC ACID EXTENSION OR AMPLIFICATION REACTIONS - Disclosed are methods and compositions related to real-time PCR and other nucleic acid extension or amplification reactions. | 01-13-2011 |
Rebecca Gusic, West Mifflin, PA US
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20100331964 | Ex Vivo Remodeling of Excised Blood Vessels for Vascular Grafts - The present invention provides an ex vivo vascular remodeling methods and system by which an excised, small diameter blood vessel can be harvested and expanded to provide viable vascular grafts, as demonstrated at the physical and molecular levels, and as optimized in vivo. The tissue-engineered vessels generated by the present invention closely resemble native vessels in terms of structure, histologically, including endothelial coverage and intricate structural components such as the internal elastic lamina, viability (as measured with MTT assay and TUNEL analysis), and function (vasoactivity, mechanical and biomechanical properties). Thus, the resulting vascular grafts behave in a manner similar to native arteries in terms of mechanical integrity, and provide clinically relevant patency rates when implanted in vivo. Moreover, the ex vivo methods and system permit the precise control of the mechanical environment involving the excised vessel, while at the same time permitting carefully monitoring of the resulting growth/remodeling, thereby opening new avenues of research regarding the mechanical stimuli responsible for specific aspects of remodeling in vivo. | 12-30-2010 |
Rebecca Hoefing, San Francisco, CA US
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20090194553 | Wipes Canister - A packaging container for dispensing wipes, which includes a lid and a base for storing a roll of wipes that is dispensed through an aperture on the base side surface from the outside of the roll inward. | 08-06-2009 |
20090194554 | Wipes Canister - A packaging container for dispensing wipes, which includes a blow-molded lid and a blow-molded base for storing a roll of wipes that is dispensed from the outside of the roll inward through an aperture in a flat, injection molded cover assembly on the curved base side surface. | 08-06-2009 |
20090194555 | Wipes Canister - A packaging container for dispensing wipes, which includes a lid and a base for storing a roll of wipes that is dispensed through an aperture on the lid side surface from the outside of the roll inward. | 08-06-2009 |
20090200328 | Wipes Canister - A dispenser for storing a roll of wet wipes including a rounded bottom surface and a lid perpendicular to the bottom surface of the dispenser so that the wipes are dispensed through the front of the dispenser as the dispenser sits on a supporting surface. | 08-13-2009 |
20100078443 | Wipes Canister Opening - A packaging container for dispensing wipes includes a lid and a base for storing wipes that are dispensed through an aperture having large and small aperture portions connected by a channel and a continuous concave curve from the large aperture portion to the small aperture portion. | 04-01-2010 |
Rebecca Hoefing, Pleasanton, CA US
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20110108447 | Shrink Sleeve on Bottle With Integral Dip Tube - Described is a shrink sleeve label for a fluid dispensing container having a bottle and fluid withdrawing assembly for liquids, such as liquid cleaners and the like. The bottle has an external integral dip tube formed at the bottle front surface and separated from the bottle by a partition. The integral dip tube fluidly connects to the bottle interior at a landing below the top of the bottle neck. A fluid dispensing mechanism, such as a pump or trigger-sprayer, is attached to the top of the bottle to take fluid up through the integral dip tube and dispense the fluid accordingly. The shrink sleeve label covers the bottle, the integral dip tube and the partition. | 05-12-2011 |
20130020354 | PROCESS OF MAKING A SHRINK SLEEVE ON A BOTTLE WITH INTEGRAL DIP TUBE - Described is a shrink sleeve label for a fluid dispensing container having a bottle and fluid withdrawing assembly for liquids, such as liquid cleaners and the like. The bottle has an external integral dip tube formed at the bottle front surface and separated from the bottle by a partition. The integral dip tube fluidly connects to the bottle interior at a landing below the top of the bottle neck. A fluid dispensing mechanism, such as a pump or trigger-sprayer, is attached to the top of the bottle to take fluid up through the integral dip tube and dispense the fluid accordingly. The shrink sleeve label covers the bottle, the integral dip tube and the partition. | 01-24-2013 |
Rebecca Illowsky, Menlo Park, CA US
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20110295678 | Expanding Ad Group Themes Using Aggregated Sequential Search Queries - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for creating ad groups based on sequential search queries are disclosed. A seed ad group theme can be selected. Aggregated sequential search queries can be obtained from a seed search query having identical terms as the seed ad group theme. The aggregated sequential search queries can be used as additional ad group themes for generating new ad groups. Keywords can be selected for each new ad groups based on one or more performance criteria. Performance of ad groups and keywords and changes in aggregated sequential search queries can be monitored for subsequent ad group creation, removal, and dynamic tuning. | 12-01-2011 |
Rebecca Jeffords, Lake Bluff, IL US
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20100170026 | Pants with Interchangeable Gusset Inserts - A pants garment has a pant leg extending vertically from about a hip region to a bottom hem, a slit extending upward from the hem, the slit vertically dividing the pant leg into a pair of mating slit edges ending at a terminus, a zipper for releasably closing the slit along the pair of mating slit edges, a gusset formed of a vertically pleated fabric material having a peripheral length sized to match the pair of mating slit edges, and snaps, buttons, zippers or hook and loop fasteners for removably attaching the peripheral length of the gusset to an interior region of the pant leg adjacent the pair of mating slit edges of the pant leg. | 07-08-2010 |
20120304361 | Pants with Interchangeable Gusset Inserts - A pants garment has a pant leg extending vertically from about a hip region to a bottom hem, a slit extending upward from the hem, the slit vertically dividing the pant leg into a pair of mating slit edges ending at a terminus, a zipper for releasably closing the slit along the pair of mating slit edges, a gusset formed of a vertically pleated fabric material having a peripheral length sized to match the pair of mating slit edges, and snaps, buttons, zippers or hook and loop fasteners for removably attaching the peripheral length of the gusset to an interior region of the pant leg adjacent the pair of mating slit edges of the pant leg. | 12-06-2012 |
20140304893 | Pants with Interchangeable Gusset Inserts - A pants garment has a pant leg extending vertically from about a hip region to a bottom hem, a slit extending upward from the hem, the slit vertically dividing the pant leg into a pair of mating slit edges ending at a terminus, a zipper for releasably closing the slit along the pair of mating slit edges, a gusset formed of a vertically pleated fabric material having a peripheral length sized to match the pair of mating slit edges, and snaps, buttons, zippers or hook and loop fasteners for removably attaching the peripheral length of the gusset to an interior region of the pant leg adjacent the pair of mating slit edges of the pant leg. | 10-16-2014 |
Rebecca Kestian, Irvine, CA US
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20090044329 | SELF-SUPPORTING SHOWER HEAD SYSTEM - A self-supporting shower head system including a hollow center section configured to couple with a flexible tube, at least one shower head coupled to the center section, and at least one telescoping rod coupled to the center section, where the at least one telescoping rod is configured to extend away from and to retract toward the center section, wherein the flexible tube is configured to couple with at least one shower outlet pipe and to provide water to the at least one shower head. | 02-19-2009 |
Rebecca Kozodoy, Randolph, MA US
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20100191172 | ILLUMINATOR FOR PHOTODYNAMIC THERAPY - An apparatus and method for photodynamic therapy or photodynamic diagnosis using an illuminator comprising a plurality of light sources generally conforming to a contoured surface and irradiating the contoured surface with substantially uniform intensity visible light. The light sources may comprise generally U-shaped fluorescent tubes that are driven by electronic ballasts. Adjustment of the ballast voltage controls the output power of the tubes. The tubes are supported by a sheet-metal or plastic housing and are covered by a polycarbonate shield which directs cooling airflow within the unit and prevents glass-patient contact in the vent of tube breakage. An aluminum reflector located behind the tubes increases both the output irradiance and the uniformity of the output distribution. The spacing of the U-shaped tubes is varied to increase the output at the edges of the illuminator to make the output more uniform. Also, different portions of the tubes are cooled at different amounts, to improve uniformity. A light sensor monitors output from the U-shaped tubes to provide a signal for adjusting the output from the tubes. | 07-29-2010 |
20110282266 | ILLUMINATOR FOR PHOTODYNAMIC THERAPY - An apparatus and method for photodynamic therapy or photodynamic diagnosis using an illuminator comprising a plurality of light sources generally conforming to a contoured surface and irradiating the contoured surface with substantially uniform intensity visible light. The light sources may comprise generally U-shaped fluorescent tubes that are driven by electronic ballasts. Adjustment of the ballast voltage controls the output power of the tubes. The tubes are supported by a sheet-metal or plastic housing and are covered by a polycarbonate shield which directs cooling airflow within the unit and prevents glass-patient contact in the vent of tube breakage. An aluminum reflector located behind the tubes increases both the output irradiance and the uniformity of the output distribution. The spacing of the U-shaped tubes is varied to increase the output at the edges of the illuminator to make the output more uniform. Also, different portions of the tubes are cooled at different amounts, to improve uniformity. A light sensor monitors output from the U-shaped tubes to provide a signal for adjusting the output from the tubes. | 11-17-2011 |
20130102906 | ILLUMINATOR FOR PHOTODYNAMIC THERAPY - An apparatus and method for photodynamic therapy or photodynamic diagnosis using an illuminator comprising a plurality of light sources generally conforming to a contoured surface and irradiating the contoured surface with substantially uniform intensity visible light. The light sources may comprise generally U-shaped fluorescent tubes that are driven by electronic ballasts. The spacing of the U-shaped tubes is varied to increase the output at the edges of the illuminator to make the output more uniform. Also, different portions of the tubes are cooled at different amounts, to improve uniformity. A light sensor monitors output from the U-shaped tubes to provide a signal for adjusting the output from the tubes. | 04-25-2013 |
Rebecca Lameire, Mechelen BE
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20120017741 | SAWING WIRE WITH ABRASIVE PARTICLES PARTLY EMBEDDED IN A METAL WIRE AND PARTLY HELD BY AN ORGANIC BINDER - A sawing wire ( | 01-26-2012 |
Rebecca Lauseng, Lake Zurich, IL US
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20100049542 | SYSTEMS, ARTICLES OF MANUFACTURE, AND METHODS FOR MANAGING BLOOD PROCESSING PROCEDURES - Systems, articles of manufacture, and methods for managing blood processing operations and data for one or more blood component collection facilities are provided. An example system for networking the blood component collection facility includes a system computer including a memory and a communication interface. The system computer is linked to a plurality of input devices for tracking donors, operators, soft goods, and blood component collection instruments with respect to one or more blood product collection procedures. The system computer is also linked to at least one administrative level computing device to monitor blood component collection activities throughout the blood component collection facility and to facilitate decision making with respect to allocation of at least one of donors, operators, soft goods, and blood component collection instruments based on information regarding at least one of donors, operators, soft goods, and blood component collection instruments. | 02-25-2010 |
Rebecca Lesic, New South Wales AU
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20100204419 | POLYMERISATION METHOD - Disclosed herein is a method of forming a polymer, wherein the polymer is formed by a radical polymerisation reaction initiated by a solid oxide compound. | 08-12-2010 |
Rebecca Lewis, Newport Beach, CA US
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20090071410 | LIVERPOOL APPARATUS - The present invention relates to a novel liverpool apparatus for use in show jumping, a category of equestrian events. Said apparatus allows a user to provide at least two types of liverpools using a single apparatus. | 03-19-2009 |
Rebecca Li, Bedford, MA US
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20100074876 | CALCIUM PHOSPHATE DELIVERY VEHICLES FOR OSTEOINDUCTIVE PROTEINS - A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an effervescent agent. Methods of making the compositions and methods of using the osteogenic compositions to treat osteoporotic and/or osteopenic bone are also disclosed. | 03-25-2010 |
20100273706 | Injectable Calcium Phosphate Solid Rods and Pastes for Delivery of Osteogenic Proteins - Osteogenic proteins are delivered via an injectable solid rod or hardenable paste. The formulation comprises a calcium phosphate material, an osteogenic protein, and optional additives and active ingredients such as a bone resorption inhibitor. Methods of making injectable pharmaceutical compositions and methods of using the osteogenic compositions to treat bone defects are also disclosed. | 10-28-2010 |
Rebecca Lidstrom, Madison, WI US
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20090301282 | Material Corner Shaper - A cutting apparatus for cutting a corner from sheet material to a selectable profile. In one set of embodiments, the cutting apparatus comprises a cutting assembly that includes a cutting element having a plurality of cutting profiles wherein each cutting profile may have a unique profile. The cutting assembly is configured such that an active cutting profile is selectable from the plurality of cutting profiles available on the cutting element. Engagement of the active cutting profile with one or more pieces of sheet material cuts a corner from the sheet material to a profile indicative of the active cutting profile. Cutting profiles may include curves having a uniform or variable radius of curvature and other forms appropriate for cutting a corner of sheet material. | 12-10-2009 |
20090301327 | Stamping Tool - A self-inking hand stamp tool for generating a stamp on a surface. In an embodiment, the self-inking hand stamp tool comprises a base, a carriage operatively coupled to the base, a stamp operatively coupled to the carriage, an inkpad operatively coupled to the base, and a housing operatively coupled to the base, wherein operation of the housing transfers the stamp from an inking orientation to a stamping orientation. The stamp may further comprise a stamp plate selectively couplable to the carriage and one or more stamp sheets selectively adherable to the stamp plate. In an embodiment, the one or more stamp sheets are selectively adhered to the stamp plate via an electrostatic force. | 12-10-2009 |
Rebecca Loevenguth, Denver, CO US
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20100250436 | MOBILE CUSTOMER SERVICE CENTERS WITH A MOBILE PICKUP MODEL - Methods and systems for redirecting the funds in a money transfer transaction are provided. The redirection of funds can be accomplished through a money redirection system. The redirection process can be initiated through a request from a recipient of the funds to change the destination of the money transfer from an intended destination to a new destination. The recipient can provide the money redirection system with a transaction identifier and with recipient identification information so that the money redirection system can verify that the recipient making the money redirection request is the recipient associated with the money transfer. After the money redirection system has verified the identity of the recipient, the money redirection system can direct a money transfer facilitator to redirect the funds. | 09-30-2010 |
20110251906 | MOBILE AGENT POINT-OF-SALE (POS) - Systems and methods are disclosed for conducting transactions and financial transfers utilizing a mobile device communicatively coupled with a mobile communications network and executing a mobile point-of-sale application. According to some embodiments, the mobile point-of-sale application is adapted to conduct money transfer transactions by communicating transaction information through the mobile communications network to a money transfer provider system that processes the money transfer and communicates receipt information to the mobile point-of-sale application. Additionally, according to some embodiments, an account associated with an agent of the money transfer provider can be used in money transfer transactions conducted by the mobile point-of-sale application. | 10-13-2011 |
20120166295 | SECURE CONTACTLESS PAYMENT SYSTEMS AND METHODS - According to the invention, a system for providing payments to a point of sale device is disclosed. The system may include a mobile device having a storage medium, an input device, a wireless transmission device, and a processor. The storage medium may include individual authentication information and device authentication information. The input device may be configured to receive an input. The wireless transmission device may be configured to selectively transmit the device authentication information to a nearby point of sale device. The processor may be configured to compare the input with the individual authentication information, and activate the wireless transmission device to transmit the device authentication information if the input is correlated with the individual authentication information. | 06-28-2012 |
Rebecca Lucente-Schultz, Houston, TX US
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20100197783 | Radiation Protection Using Single Wall Carbon Nanotube Derivatives - A method of reducing side effects of damage in a human subject exposed to radiation includes administering to the human subject carbon nanotubes in a pharmaceutically acceptable carrier after or prior to exposure to radiation. A composition for reducing radical damage includes a carbon nanotube which is functionalized (1) for substantial water solubility and (2) with a radical trapping agent appended to the carbon nanotube forming a radical scavenger-carbon nanotube conjugate. | 08-05-2010 |
Rebecca Mallaband, Loughborough GB
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20080297830 | PRINTER WITH OUTSOURCING CAPABILITY FOR COLOR COPIES - A printing system includes first and second communicatively linked printers, each including a print engine and a processor which controls the operation of the respective print engine. A scanner, associated with the first printer, scans a hardcopy document and generates image data therefrom. The scanner is for communicating the image data to the first printer. A graphical user interface is provided through which user selections are communicated to at least one of the scanner and the first printer. The first processor has a first mode of operation in which a print job derived from the image data is printed on the first print engine and a second mode of operation in which a print job is exported to the second printer for printing. At least one of the first and second modes of operation is invoked at least in part by user interaction with the graphical user interface. | 12-04-2008 |
Rebecca Mcgirr, London CA
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20100297022 | Magnetosome Gene Expression in Eukaryotic Cells - The invention is the production of magnetosome-like structures in cells. The invention provides in vitro and in vivo diagnostic and therapeutic methods using eukaryotic cells expressing magnetosome-like structures that act as contrast agents. | 11-25-2010 |
Rebecca Mengay, Medina, OH US
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20120168529 | TASSEL ASSEMBLY INCLUDING A FRAGRANCE DELIVERY ARRANGEMENT - A fragrance delivery system similar in appearance, or used in similar locations as a tassel assembly having a fragrance delivery arrangement is provided. The fragrance delivery system similar in appearance, or used in similar locations as a tassel includes an attachment component for hanging the fragrance delivery system similar in appearance, or used in similar locations a tassel, from a conventional supporting article, a head component having a decorative configuration and a skirt component connected to the head component. The skirt component includes a support member and may or may not include a skirt of various materials including strings, cloth, ribbons, wood, glass, plastic or other decorative elements suspended from the support member. A fragrance delivery arrangement is releasably connected to the head component and may or may not be at least partially concealed by the skirt. | 07-05-2012 |
Rebecca Mostatab, Gladwyne, PA US
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20120054973 | Flossibility - A gum cleaning tool for cleaning and massaging a gum of a user may include a handle portion for the user to hold the gum cleaning tool, and a cleaning portion to cooperate with the handle portion to clean and massage the gum of the user. The cleaning portion may include a radial bristle. The cleaning portion may be curved, and the cleaning portion may be is concavely curved. The handle portion may define a plane and the concavely curved cleaning portion is formed within the plane, and the cleaning portion may be flexible. The cleaning portion may be formed from rubber, and the cleaning portion may be formed from flexible plastic. | 03-08-2012 |
Rebecca Neth Townsend, Bellevue, WA US
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20120035509 | GAIT ANALYSIS SYSTEM AND METHODS - Systems and methods for analyzing the gait of an individual are disclosed. The disclosed systems and methods can be configured to acquire data from a first array and a second array of sensors that are configured to be placed in a left and/or right shoe, respectively. The acquired data can be collected or separated into at least two separate gait phases for each array, compared to a baseline condition for each gait phase and categorized into one of at least two uniformity categories for each gait phase. Examples of collected and/or calculated data include pressure values, shear stress values and torque values. The analysis can be focused on both feet of a person, or focused on one foot. A graphical output showing at least one entire gait cycle based on the uniformity categories can then be generated. | 02-09-2012 |
20140094717 | GAIT ANALYSIS SYSTEM AND METHODS - Systems and methods for analyzing the gait of an individual are disclosed. The disclosed systems and methods can be configured to acquire data from a first array and a second array of sensors that are configured to be placed in a left and/or right shoe, respectively. The acquired data can be collected or separated into at least two separate gait phases for each array, compared to a baseline condition for each gait phase and categorized into one of at least two uniformity categories for each gait phase. Examples of collected and/or calculated data include pressure values, shear stress values and torque values. The analysis can be focused on both feet of a person, or focused on one foot. A graphical output showing at least one entire gait cycle based on the uniformity categories can then be generated. | 04-03-2014 |
Rebecca Noreen, Eden Prairie, MN US
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20080288286 | Systems and Methods of Analyzing Healthcare Data - The present invention provides systems and methods of analyzing healthcare data. In one embodiment, a Medical National Operations Center application (MNOC) displays clear, concise and actionable information, with visual indicators, to help Line of Service (LOS) teams to manage their operations by providing a dashboard of information. For example, the application may present selected summaries of data, baseline targets, customized metrics and interactive alerts that will be used to monitor, analyze and measure LOS performance. In one embodiment, the systems and methods of the present invention may be implemented in a health insurance provider system. As such, the present invention may provide access to additional, real-time data to evaluate initiatives allowing the LOS to react quickly to variances and expected results. Further, the present invention may provide tools to evaluate the effectiveness and performance of initiatives and programs, such as, for example, member steerage tools. | 11-20-2008 |
Rebecca Oldham-Haltom, Marshall, WI US
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20120122105 | REAL TIME CLEAVAGE ASSAY - A cleavage-based real-time PCR assay method is provided. In general terms, the assay method includes subjecting a reaction mixture comprising a) PCR reagents for amplifying a nucleic acid target, and b) flap cleavage reagents for performing a flap cleavage assay on the amplified nucleic acid target to two sets of thermocycling conditions. No additional reagents are added to the reaction between said first and second sets of cycles and, in each cycle of the second set of cycles, cleavage of a flap probe is measured. | 05-17-2012 |
20130143216 | Real Time Cleavage Assay - A cleavage-based real-time PCR assay method is provided. In general terms, the assay method includes subjecting a reaction mixture comprising a) PCR reagents for amplifying a nucleic acid target, and b) flap cleavage reagents for performing a flap cleavage assay on the amplified nucleic acid target to two sets of thermocycling conditions. No additional reagents are added to the reaction between said first and second sets of cycles and, in each cycle of the second set of cycles, cleavage of a flap probe is measured. | 06-06-2013 |
20130231256 | MULTIPLEXED KRAS MUTATION DETECTION ASSAY - Provided herein is reagent mixture comprising multiplexed amplification reagents and flap assay reagents for detecting, in a single reaction, mutant copies of the KRAS gene that contain any of the 34A, 34C, 34T, 35A, 35C, 35T or 38A point mutations. Methods that employ the reagent mix and kits for performing the same are also provided. | 09-05-2013 |
20140087382 | NORMALIZATION OF POLYMERASE ACTIVITY - Provided herein is technology relating to the amplification-based detection of nucleic acids and particularly, but not exclusively, to methods and compositions for minimizing variability in the activity between different samples or manufacturing lots of DNA polymerases, such as Taq DNA polymerase. | 03-27-2014 |
Rebecca Pieroth, Ronneburg DE
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20110178246 | BLOCK COPOLYMERS ON THE BASIS OF (METH)ACRYLATE - The invention relates to block copolymers produced by means of controlled polymerization and that have at least one block A or B comprising (meth)acrylate monomers and copolymerizable monomers, and a block P on the basis of functionalized polymers. | 07-21-2011 |
20130172511 | BLOCK COPOLYMERS ON THE BASIS OF (METH)ACRYLATE - The invention relates to block copolymers produced by means of controlled polymerization and that have at least one block A or B comprising (meth)acrylate monomers and copolymerizable monomers, and a block P on the basis of functionalized polymers. | 07-04-2013 |
Rebecca Pogni, Siena IT
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20100000032 | PHENOXAZINE DYES - The present invention concerns highly water-soluble phenoxazines dyes of formula (I) | 01-07-2010 |
Rebecca Pogue-Caley, Durham, NC US
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20090053251 | Dendritic Cell Compositions and Methods - Methods are provided for the production of dendritic cells from monocytes that have been incubated at a temperature of 1° C.-34° C. for a period of approximately 6 to 96 hours from the time they are isolated from a subject. After the incubation period, the monocytes can then be induced to differentiate into dendritic cells. Mature dendritic cells made by the methods of the invention have increased levels of one or more of CD80, CD83, CD86, MHC class I molecules, or MHC class II molecules as compared to mature dendritic cells prepared from monocytes that have not been held at 1° C.-34° C. for at least 6 hours from the time they were isolated from a subject. Dendritic cells made by the methods of the invention are useful for the preparation of vaccines and for the stimulation of T cells. | 02-26-2009 |
20120114680 | Dendritic Cell Compositions and Methods - Methods are provided for the production of dendritic cells from monocytes that have been incubated at a temperature of 1° C.-34° C. for a period of approximately 6 to 96 hours from the time they are isolated from a subject. After the incubation period, the monocytes can then be induced to differentiate into dendritic cells. Mature dendritic cells made by the methods of the invention have increased levels of one or more of CD80, CD83, CD86, MHC class I molecules, or MHC class II molecules as compared to mature dendritic cells prepared from monocytes that have not been held at 1° C.-34° C. for at least 6 hours from the time they were isolated from a subject. Dendritic cells made by the methods of the invention are useful for the preparation of vaccines and for the stimulation of T cells. | 05-10-2012 |
20130280805 | Dendritic Cell Compositions and Methods - Methods are provided for the production of dendritic cells from monocytes that have been incubated at a temperature of 1° C.-34° C. for a period of approximately 6 to 96 hours from the time they are isolated from a subject. After the incubation period, the monocytes can then be induced to differentiate into dendritic cells. Mature dendritic cells made by the methods of the invention have increased levels of one or more of CD80, CD83, CD86, MHC class I molecules, or MHC class II molecules as compared to mature dendritic cells prepared from monocytes that have not been held at 1° C.-34° C. for at least 6 hours from the time they were isolated from a subject. Dendritic cells made by the methods of the invention are useful for the preparation of vaccines and for the stimulation of T cells. | 10-24-2013 |
Rebecca Potash, Pittsburgh, PA US
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20110111138 | METAL INK COMPOSITIONS, CONDUCTIVE PATTERNS, METHODS, AND DEVICES - Metal complexes adapted to form conductive metal films and lines upon deposition and treatment. The metal complex can be a covalent complex and can comprise a first and second ligand. Low temperature treatment can be used to convert the complex to a metal. The metal films and lines can have low resistivity and work function similar to pure metal. Coinage metals can be used (e.g., Ag, Au, Cu). The ligands can be dative bonding ligands including amines, unsymmetrical amines, and carboxylate ligands. Sulfur complexes can be used. Carboxylate ligands can be used. The complexes can have a high concentration of metal and can be soluble in aromatic hydrocarbon solvent. The ligands can be adapted to volatilize well. Inkjet printing can be carried out. High yields of metal can be achieve with high conductivity. | 05-12-2011 |
Rebecca Pulk, San Francisco, CA US
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20110201593 | TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF - The invention provides novel compounds of formula I having the general formula: | 08-18-2011 |
Rebecca Pulk, South San Francisco, CA US
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20120157439 | RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF - Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. | 06-21-2012 |
20120214811 | RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF - Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. | 08-23-2012 |
Rebecca Rone, Columbia, MO US
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20120070466 | Conjugated Polymeric Material and Uses Thereof - Disclosed are compositions comprising collagen covalently bound to particles, wherein covalent bonds are formed between reactive groups of the collagen and reactive groups of the particles, and wherein the particles have an average particle diameter ranging from 20 to 1000 nanometers. Also disclosed are various methods that utilize the compositions. | 03-22-2012 |
20140302104 | CONJUGATED POLYMERIC MATERIAL AND USES THEREOF - Disclosed are compositions comprising collagen covalently bound to particles, wherein covalent bonds are formed between reactive groups of the collagen and reactive groups of the particles, and wherein the particles have an average particle diameter ranging from 20 to 1000 nanometers. Also disclosed are various methods that utilize the compositions. | 10-09-2014 |
Rebecca Roti, Wauwatosa, WI US
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20090090485 | MATERIAL USED TO COMBAT THERMAL EXPANSION RELATED DEFECTS IN THE METAL CASTING PROCESS - Thermal expansion defects, i.e. veining, are reduced in iron, steel, and nonferrous castings by adding a lithia-containing material in a sufficient amount to the silica sand mold. Adjusting current formulations to maximize the use of lesser expensive raw materials and minimize the use of more expensive raw materials to lower the overall percentages of lithia/metallic oxide containing additives while still reducing or eliminating thermal expansion related defects in the metal casting process reduces the overall cost to manufacture the product. | 04-09-2009 |
20090114364 | MATERIAL USED TO COMBAT THERMAL EXPANSION RELATED DEFECTS IN HIGH TEMPERATURE CASTING PROCESSES - An additive to foundry sand molding and core aggregates is used to produce sand cores and molds. The additive produces a sand-based foundry molding and core aggregate which resists the formation of some of the defects commonly associated with the production of castings produced by silica sand-based molding and core aggregates. In particular, the additive improves the quality of castings poured at temperatures higher than those of the pouring temperatures of molten iron, such as in steel castings, and in iron castings with “hot spots.” | 05-07-2009 |
20090114365 | MATERIAL USED TO COMBAT THERMAL EXPANSION RELATED DEFECTS IN HIGH TEMPERATURE CASTING PROCESSES - An additive to foundry sand molding and core aggregates is used to produce sand cores and molds. The additive produces a sand-based foundry molding and core aggregate which resists the formation of some of the defects commonly associated with the production of castings produced by silica sand-based molding and core aggregates. In particular, the additive improves the quality of castings poured at temperatures higher than those of the pouring temperatures of molten iron, such as in steel castings and in iron castings with “hot spots.” | 05-07-2009 |
Rebecca Shatsky, Los Altos, CA US
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20100292611 | Method and apparatus for improving fluidic flow and sample capture - A system and method is provided for the capture of bodily fluid upon lancing of a patient. In one embodiment, the fluid sample capture aperture mesh ( | 11-18-2010 |
Rebecca Silvernail, Austin, TX US
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20100139682 | Method and apparatus for precise deposition of hair care agents - An apparatus and control method provides for automated, computer control to illuminate hair, sense aspects of that hair, calculate enhancements based on the sensed aspects of the hair, and precisely apply compounds on the hair in spatial conformance with the sensed aspects to create those enhancements. Examples of such compounds are hair coloring agents and hair care agents. | 06-10-2010 |
Rebecca Silveston-Keith, Lexington, KY US
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20120170073 | SYSTEM FOR PREVIEWING AND IMAGING DOCUMENTS - A system for previewing and imaging a document includes an imaging unit having an imaging surface configured to carry the document thereon. The imaging unit also includes an image sensing member configured to capture an image corresponding to the document and an image processing member communicably coupled to the image sensing member to receive the captured image. The image processing member is further configured to convert the captured image to a digital data format. The system further includes a display unit communicably coupled to the image processing member. The display unit includes a user interface configured to exhibit a placement-guiding display object over converted captured image. | 07-05-2012 |
Rebecca Smith, Nine Mile Falls, WA US
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20080251524 | Containment Systems for Folding Leg Tables - Containment systems for folding leg tables are disclosed. In one embodiment, a containment system for a folding leg table includes first and second side panels attached along a lower portion of a perimeter edge. An upper portion of the perimeter edge is selectively openable by a coupling device. The first and second side panels define an interior region therebetween that is configured to receive the folding leg table. Elongated carrying handles are disposed transversely across the lower portion of the perimeter edge, each carrying handle having a first end coupled to the first side panel and a second end coupled to the second side panel. The carrying handles are configured about the perimeter edge in the manner of a stirrup. | 10-16-2008 |
Rebecca Sroufe, Germantown, OH US
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20080288337 | Template-Based Targeted Marketing - Systems, methods, and computer-readable media provide for the creation of a template-based targeted marketing presentation. According to various embodiments described herein, a sales representative utilizes a workstation to request a marketing presentation for a certain category of customer within a particular market. A presentation engine retrieves applicable up-to-date data corresponding to the customer category and market from a database and uses the data to make one or more Return On Investment (ROI) calculations. One or more presentation templates include data insertion locations. The one or more ROI calculations and other retrieved data is used to populate the data insertion locations of a selected presentation template. Once populated, the resulting marketing presentation is customized with targeted data and statistics for presenting to the customer. | 11-20-2008 |
Rebecca Stoermer Golightly, Belmond, CA US
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20110124117 | SERS NANOTAG ASSAYS WITH ENHANCED ASSAY KINETICS - Methods and systems for the use of surface-enhanced Raman scattering nanotags (SERS nanotags) in various assay platforms which feature accelerated reaction kinetics. One embodiment includes a method detecting a substance of interest by associating a SERS nanotag with the substance of interest while accelerating the reaction kinetics of the association steps. This method also includes detecting a Raman spectrum of a reporter molecule associated with the SERS nanotag. The reaction kinetics of the assay may be accelerated by applying microwave radiation to the sample, heating the sample, agitating the sample, mixing the sample, vibrating the sample or other methods. | 05-26-2011 |
Rebecca Stopps, London GB
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20090306255 | NOVEL WATER-BASED ADHESIVES FOR INDUSTRIAL APPLICATIONS - The invention relates to water-based adhesives for industrial applications obtained by mixing water-redispersible polymer powder and water-soluble polymer powder with water, wherein the weight ratio of the water-redispersible polymer powder to the water-soluble polymer powder is from about 0.001:1 to 100:1 and the water-based adhesive has a set speed of less than 300 sec, when measured with a 36 μm thick layer at 23° C. and 50% relative humidity and 385 μm thick carton boards with a weight of 275+/−3 g/m2 and Cobb values on one side of 43 g/min/m2 and 27 g/min/m2 on the other side, has a solids content of about 7.5 to 70 wt.-% and a Brookfield viscosity at 23° C. at 20 rpm, measured according to the ASTM D1084 standard, of about 500 to 10,000 mPas. The water-based industrial adhesive has the capability to bond a low surface tension substrate to a cellulosic substrate, in particular with a weight-ratio of water-redispersible polymer powder to water-soluble polymer powder from about 0.5:1 to 100:1 thus can replace conventional aqueous adhesives based on synthetic polymer dispersions. The benefits of the invention are manifold such as faster set speeds and increased machine speeds, logistical advantages due to handling powders instead of liquids, leading to e.g. prolonged shelf life, no water transportation and being an environmentally friendly, low VOC containing adhesive. | 12-10-2009 |
Rebecca Sutphen, Tampa, FL US
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20100190662 | METHODS AND MATERIALS FOR DETECTION, DIAGNOSIS AND MANAGEMENT OF OVARIAN CANCER - The subject invention concerns methods using a panel of proteins to detect, diagnose, and monitor therapy during treatment of ovarian cancer in a female patient. The proteins were identified using proteomics analyses of plasma samples obtained preoperatively from ovarian cancer patients versus those of healthy control women. Such a panel has utility for the diagnosis of ovarian cancer, screening for ovarian cancer and possibly therapeutic monitoring. | 07-29-2010 |
20100291690 | METHODS FOR DETECTING OR MONITORING CANCER USING LPC AS A MARKER - A method of detecting a cancer, such as ovarian cancer, in a test subject including (a) determining the amount of a lysophosphatidyl choline in a sample of a bodily fluid taken from the test subject, and (b) comparing the amount of the lysophosphatidyl choline in the sample of the bodily fluid taken from the test subject to a range of amounts of lysophosphatidyl choline found in samples of the bodily fluid taken from a group of normal subjects of the same species as the test subject and lacking the cancer, such as ovarian cancer, whereby a change in the amount of the lysophosphatidyl choline in the sample of the bodily fluid taken from the test subject indicates the presence of the cancer, such as ovarian cancer. | 11-18-2010 |
20110059543 | METHODS FOR DETECTING OR MONITORING CANCER USING LPE AS A MARKER - A method of detecting a cancer, such as ovarian cancer, in a test subject including (a) determining the amount of a lysophosphatidyl ethanolamine in a sample of a bodily fluid taken from the test subject, and (b) comparing the amount of the lysophosphatidyl ethanolamine in the sample of the bodily fluid taken from the test subject to a range of amounts of the lysophosphatidyl ethanolamine found in samples of the bodily fluid taken from a group of normal subjects of the same species as the test subject and lacking the cancer, such as ovarian cancer, whereby a change in the amount of the lysophosphatidyl ethanolamine in the sample of the bodily fluid from the test subject indicates the presence of the cancer, such as ovarian cancer. | 03-10-2011 |
20140162891 | METHODS AND MATERIALS FOR DETECTION, DIAGNOSIS AND MANAGEMENT OF OVARIAN CANCER - The subject invention concerns methods using a panel of proteins to detect, diagnose, and monitor therapy during treatment of ovarian cancer in a female patient. The proteins were identified using proteomics analyses of plasma samples obtained preoperatively from ovarian cancer patients versus those of healthy control women. Such a panel has utility for the diagnosis of ovarian cancer, screening for ovarian cancer and possibly therapeutic monitoring. | 06-12-2014 |
Rebecca Tagett, Marseille FR
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20110244459 | METHODS FOR IDENTIFYING ERBB2 ALTERATION IN TUMORS - Methods for identifying ERBB2 (also named HER2) alteration in tumors, in particular cancer, based on the analysis of the expression of at least three genes of the ERBB2 amplicon located within less than one megabase on either side of ERBB2, and eventually of the gene corresponding to the Affymetrix probeset 234046_at (SEQ ID NO: 31), as well as a poynucleotide library useful for the molecular characterization of a cancer including polynucleotide sequences for detecting the genes, and a kit including the library. | 10-06-2011 |
Rebecca Terns, Athens, GA US
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20110189776 | PROKARYOTIC RNAi-LIKE SYSTEM AND METHODS OF USE - Provided herein are methods for inactivating a target polynucleotide. The methods use a psiRNA having a 5′ region and a 3′ region. The 5′ region includes, but is not limited to, 5 to 10 nucleotides chosen from a repeat from a CRISPR locus immediately upstream of a spacer. The 3′ region is substantially complementary to a portion of the target polynucleotide. The methods may be practiced in a prokaryotic microbe or in vitro. Also provided are polypeptides that have endonuclease activity in the presence of a psiRNA and a target polynucleotide, and methods for using the polypeptides. | 08-04-2011 |
Rebecca Trierweiler, White Lake, MI US
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20090118954 | METHOD FOR MONITORING AN AUXILIARY PUMP FOR A HYBRID POWERTRAIN - A powertrain system includes a hybrid transmission coupled to an engine and an auxiliary hydraulic pump. The auxiliary hydraulic pump is commanded to operate at a predetermined speed only when enable criteria are met. An engine-off state is inhibited based upon a difference between a commanded speed and a monitored operating speed of the auxiliary hydraulic pump. | 05-07-2009 |
Rebecca Volovsek, Hudson, WI US
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20120078359 | ADJUSTABLE ANNULOPLASTY RING SUPPORT - A support for an adjustable annuloplasty ring generally includes a body and a groove. The body has a first end, a second end and an outer surface. The body may also include an inner surface defining a longitudinal bore. The outer surface is configured to slidably receive an annuloplasty ring and a length of adjustable suture. The groove is formed along at least a portion of the outer surface of the body and is dimensioned to receive at least a portion of the suture. | 03-29-2012 |
20130073031 | SYSTEMS AND METHODS FOR HOLDING ANNULOPLASTY RINGS - Holders for releasably holding annuloplasty rings prior to and during the implantation of the rings employ any of a variety of features relating to such things as holder shape, handle attachment structures, securement of a ring to the holder, and release of the ring from the holder. In one aspect, the holder includes a flexible bracket and a more rigid connector. In another aspect, the holder includes a flexible bracket and cutting blocks, wherein the interior surface of the cutting block is made of a higher durometer material than the bracket. The interior surface of the cutting block can be coated with a higher durometer material than the material of the bracket. In another aspect, the holder includes a flexible bracket and cutting blocks made of a higher durometer material than the flexible bracket. | 03-21-2013 |
20130197632 | ADJUSTMENT SUTURE MARKERS FOR ADJUSTABLE ANNULOPLASTY RING - An adjustable annuloplasty ring includes a body in the form of an endless loop having an internal lumen therethrough, an adjustment suture extending through at least a portion of the internal lumen, a first portion of the suture exiting the lumen through a first opening in the body and a second portion of the suture exiting the lumen through a second opening in the body, and a first adjustment marker on the first portion of the suture outside of the body. The suture may be adapted to reduce the length of the body around the loop when tightened. | 08-01-2013 |
Rebecca Wells, Wynnewood, PA US
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20110028828 | T1 RHO MAGNETIC RESONANCE IMAGING FOR STAGING OF HEPATIC FIBROSIS - Methods for diagnosis of fibrotic diseases, staging of fibrotic diseases and monitoring treatment of fibrosis. The presence of fibrotic tissue is detected. First, a T | 02-03-2011 |
Rebecca Whipple-Bettes, Elkridge, MD US
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20110021440 | APOPTOTIC PATHWAY TARGETING FOR THE DIAGNOSIS AND TREATMENT OF CANCER - The invention relates to methods of treating cancer. The invention further relates to a method of treating cancer by exploiting apoptotic pathways. The invention particularly relates to regulation of apoptotic pathways in cancerous cells, to metastasis of cancer cells, and to methods of preventing cancer metastasis. | 01-27-2011 |
Rebecca Whipple-Bettes, Columbia, MD US
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20090137473 | INHIBITION OF MICROTUBULE PROTRUSION IN CANCER CELLS - The present invention generally concerns microtubule protrusions in cancer cells, including detached cancer cells, and inhibition of the protrusions. In particular aspects, the inhibition of the protrusions interferes with attachment of the cell to a vessel wall, and in further aspects the cell is killed by forcing it to enter capillaries and be destroyed, for example by shearing. Inhibition by a variety of agents and methods is contemplated. | 05-28-2009 |
Rebecca Yang, Los Angeles, CA US
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20090238818 | Induction of Antigen Specific Immunnologic Tolerance - Antigen specific immune tolerance is induced in a mammalian host by administration of a toleragen in combination with a regimen of immunosuppression. The methods optionally include a preceding conditioning period, where immunosuppressive agents are administered in the absence of the toleragen. After the tolerizing regimen, the host is withdrawn from the suppressive agents, but is able to maintain specific immune tolerance to the immunogenic epitopes present on the toleragen. Optimally, the toleragen will have high uptake properties that allow uptake in vivo at low concentrations in a wide variety of tolerizing cell types. | 09-24-2009 |
Rebecca Zmarzly, Ronneburg DE
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20080237529 | Sprayable Acoustic Compositions - The invention relates to sprayable acoustic compositions, production processes and uses. | 10-02-2008 |