Cleary, US
Andrew J. Cleary, Liverpool, NY US
Patent application number | Description | Published |
---|---|---|
20130033969 | TRANSDUCER AND SYSTEM OF ARRANGEMENT FOR A PANEL ARRAY - A sensor system includes a pressure sensor portion, and an accelerometer. Outputs from the sensor system are handled by a signal processing system that includes a first beamforming module for inputs from a pressure sensor, a second beamforming module for inputs from an accelerometer, and an adaptive beam interpolation module. A method for signal processing signals from both a pressure sensor and an accelerometer. An array of sensors transfers data wirelessly. | 02-07-2013 |
Arthur L. Cleary, Fort Myes, FL US
Patent application number | Description | Published |
---|---|---|
20100259589 | INERT UV INKJET PRINTING - Enhanced printing solutions are enabled by providing ultraviolet curing conditions without requiring complete evacuation of atmospheric oxygen. Increased ink coverage and adjusted surface appearance are also provided. | 10-14-2010 |
Brian Cleary, Cleveland, OH US
Patent application number | Description | Published |
---|---|---|
20130139418 | GREETING CARD WITH SPRING LOADED SLIDE TRACK AUDIO TRIGGER - An interactive greeting card having a multi-panel greeting card body, a sound module and a molded track contained between two or more panels of the multi-panel greeting card body, and a moveable object which is attached to the molded track through an opening in one or more of the greeting card panels. The moveable object is operative to move from one end of the molded track to the opposite end of the molded track whereby playback of a pre-recorded digital audio file is initiated. The interactive greeting card may additionally contain a small motor which causes movement of a second moveable object and an object launcher which is operative to launch an object along the track and into the air. Other special effects may be included such as lights, additional sounds or movement, or any other special effects which can be incorporated into a greeting card. | 06-06-2013 |
Brian P. Cleary, Webster, NY US
Patent application number | Description | Published |
---|---|---|
20140000477 | PIGMENT-BASED INKJET INKS | 01-02-2014 |
Charles Brian Cleary, Alpharetta, GA US
Patent application number | Description | Published |
---|---|---|
20150358475 | ENRICHING AND ANALYZING CDR DATA TO IDENTIFY VOICE TRAFFIC ROUTING THROUGH AN INTERMEDIATE PROVIDER - A method describes enriching a Call Detail Record (CDR) to identify traffic routing through network providers. The method comprises the steps of obtaining Operator Carrier Numbers (OCNs) assigned to network providers operating in a network; obtaining trunk group identifiers for identifying trunks configured to interconnect an Originating Provider's network including a Mobile Switching Center (MSC) with network providers; and identifying network providers configured to communicate through the trunk groups with the Originating Provider's network, including the MSC. The method also obtains a Called Party Number (CdPN) from the CDR; and associates the CdPN with an OCN of a network provider. The method also determines whether the OCN associated with the trunk group and the OCN of the CdPN are the same. If they are the same, then the method concludes that the Originating Provider, including the MSC is communicating directly with the network provider without any other network provider operating as an Intermediate Provider; if they are not the same, then the method concludes that the Originating Provider including the MSC is communicating indirectly with the network provide involving another network provider operating as an Intermediate Provider. | 12-10-2015 |
20160028897 | METHOD TO DETERMINE THE JURISDICTION OF CMRS TRAFFIC VIA CELL SITE LOCATION AND RATE CENTER - A method includes receiving, at a processor, Call Detail Records (CDRs) from a Data Mediation System, in which each CDR includes a called party number (CdPN) associated with a first device, and a Cell Site ID associated with a location of a cell carrying a communication from a second device. Also included are: obtaining, from a first digital table, a first Major Trading Area (MTA) associated with the CdPN; obtaining, from a second digital table, a second MTA associated with the Cell Site ID; and concluding that the first and second devices are communicating in Local Traffic, if the first MTA is the same as the second MTA. | 01-28-2016 |
Daniel Joseph Cleary, Schenectady, NY US
Patent application number | Description | Published |
---|---|---|
20080243328 | METHOD AND SYSTEM FOR DIAGNOSING FAULTS IN A PARTICULAR DEVICE WITHIN A FLEET OF DEVICES - A method for diagnosing faults in a particular device within a fleet of devices is provided. The method comprises receiving performance data related to one or more parameters associated with a fleet of devices and processing the performance data to detect one or more trend shifts in the one or more parameters. The method then comprises detrending the one or more parameters to derive noise-adjusted performance data related to a particular parameter associated with a particular device. The method further comprises generating a fleet-based diagnostic model based on trend patterns and data characteristics associated with the fleet of devices. The fleet-based diagnostic model comprises one or more fuzzy rules defining one or more expected trend shift data ranges for the one or more parameters associated with the fleet of devices. The method then comprises computing one or more scaling factors for the particular parameter associated with the particular device and scaling the one or more of fuzzy rules defined for the one or more parameters in the fleet-based diagnostic model, based on the one or more scaling factors, to generate a personalized diagnostic model for the particular parameter associated with the particular device. The method finally comprises evaluating the personalized diagnostic model against the one or more trend shifts detected for the one or more parameters, to diagnose a fault associated with the particular device. | 10-02-2008 |
20120158826 | SYSTEM AND METHOD FOR PROVIDING AN OPTIMAL MOTIVATIONAL RESPONSE - A system for providing an optimal motivational response is provided. The system includes an input device configured to receive at least one client input from the client. The system further includes a processor configured to analyze the at least one client input received from the client and generate a current state of the client based on the at least one client input. The processor is further configured to analyze the current state of the client and determine an optimal motivational technique for the client based on the current state of the client and the at least one client input. The processor is also configured to generate an optimal motivational response based on the optimal motivational technique. The system further includes an output device configured to display the optimal motivational response to the client. | 06-21-2012 |
20130053653 | RADAR BASED SYSTEMS AND METHODS FOR MONITORING A SUBJECT - Methods and systems for monitoring a subject in a resting state using one or more range-controlled radars are presented. The radars non-invasively detect one or more motion and/or physiological parameters corresponding to the subject. The motion parameters comprise one or more activity levels and the physiological parameters comprise one or more of heartbeat and respiration. Further, one or more patterns in the motion parameters detected over a designated motion period of time are determined Additionally, one or more patterns in the physiological parameters detected over the designated physiological period of time are also determined The systems then assess a health condition of the subject based on the determined patterns of the motion parameters and/or the determined patterns of the physiological parameters. | 02-28-2013 |
20140095181 | METHODS AND SYSTEMS FOR MANAGING PERFORMANCE BASED SLEEP PATIENT CARE PROTOCOLS - Methods, systems and non-transitory computer readable media for automated workflow management for sleep quality are presented. A subject in a resting state is monitored using one or more sensors for acquiring one or more physiological parameters. A phase of sleep of the subject at a specific time using the physiological parameters is detected and inferred. Further, a recuperative benefit of the detected sleep phase is estimated. Additionally, it is determined is if an activity in a patient care workflow scheduled proximate to the specific time hinders sleep of the subject. The patient care workflow is then automatically reconfigured if scheduled activity hinders patient sleep, if the determined recuperative benefits exceed a designated threshold and/or if a proposed reconfiguration satisfies one or more designated criteria accounting for both restorative benefits to the patient and objectives of competing care delivery activities for both a given patient and a department. | 04-03-2014 |
Darryl G. Cleary, Chapel Hill, NC US
Patent application number | Description | Published |
---|---|---|
20110130559 | Methods to Manufacture 1,3-Dioxolane Nucleosides - This application provides a process for preparing enantiomerically pure β-D-dioxolane nucleosides. In particular, a new synthesis of (−)-DAPD, suitable for large scale development, is described. In one embodiment the invention provides a process for preparing a substantially pure β-D- or β-L-1,3-dioxolane nucleosides comprising a) preparing or obtaining an esterified 2,2-dialkoxy ethanol; b) cyclizing the esterified 2,2-dialkoxy ethanol with glycolic acid to obtain a 1,3-dioxolane lactone; c) resolving the 1,3-dioxolane lactone to obtain a substantially pure D- or L-lactone; d) selectively reducing and activating the D- or L-chiral lactone to obtain a substantially pure D- or L-1,3-dioxolane; e) coupling the D- or L-1,3-dioxolane to an activated and/or protected purine or pyrimidine base; and f) optionally purifying the nucleoside to obtain a substantially pure protected β-D- or β-L-1,3-dioxolane nucleoside. | 06-02-2011 |
20130136776 | COMPOSITIONS AND METHODS FOR TREATING HEPATITIS C VIRUS - Disclosed herein are a composition and unit dosage form for the treatment of hepatitis C virus (HCV) infection comprising GS-7977 and at least one pharmaceutically acceptable excipient, as well as methods for making said composition and unit dosage form. Also disclosed herein is a method of treating a subject, preferably a human, infected with hepatitis C virus, said method comprising administering to the subject for a time period an effective amount of GS-7977 and an effective amount of ribavirin. In one aspect, the method comprises administering to the subject an interferon-free treatment regimen comprising an effective amount of GS-7977 and an effective amount of ribavirin. In a particular aspect, the method is sufficient to produce an undetectable amount of HCV RNA in the subject for at least 12 weeks after the end of the time period. | 05-30-2013 |
20150150896 | COMPOSITIONS AND METHODS FOR TREATING HEPATITIS C VIRUS - Disclosed herein are a composition and unit dosage form for the treatment of hepatitis C virus (HCV) infection comprising GS-7977 and at least one pharmaceutically acceptable excipient, as well as methods for making said composition and unit dosage form. Also disclosed herein is a method of treating a subject, preferably a human, infected with hepatitis C virus, said method comprising administering to the subject for a time period an effective amount of GS-7977 and an effective amount of ribavirin. In one aspect, the method comprises administering to the subject an interferon-free treatment regimen comprising an effective amount of GS-7977 and an effective amount of ribavirin. In a particular aspect, the method is sufficient to produce an undetectable amount of HCV RNA in the subject for at least 12 weeks after the end of the time period. | 06-04-2015 |
David Cleary, Bloomington, MN US
Patent application number | Description | Published |
---|---|---|
20090268609 | EFFICIENT MANAGEMENT OF RING NETWORKS - In general, techniques are described for efficient management of ring networks with a system of two network devices. The first network device of the ring network is designated as an adjacent selective forwarding (ASF) device, and the second network device is designated as a master device. The master device monitors the ring network to determine whether a fault has occurred in the ring network and transmits via a secondary port of the master device a network status message to the ASF device based on the determination of whether the fault has occurred. The ASF device determines a status of the ring network based on the network status message and selectively forwards data traffic to the master network device based on the determination of the status. As a result, the master device more efficiently utilizes network resources by not consuming processor or memory resources to prevent traffic loops. | 10-29-2009 |
20110267940 | EFFICIENT MANAGEMENT OF RING NETWORKS - In general, techniques are described for efficient management of ring networks with a system of two network devices. The first network device of the ring network is designated as an adjacent selective forwarding (ASF) device, and the second network device is designated as a master device. The master device monitors the ring network to determine whether a fault has occurred in the ring network and transmits via a secondary port of the master device a network status message to the ASF device based on the determination of whether the fault has occurred. The ASF device determines a status of the ring network based on the network status message and selectively forwards data traffic to the master network device based on the determination of the status. As a result, the master device more efficiently utilizes network resources by not consuming processor or memory resources to prevent traffic loops. | 11-03-2011 |
David D. Cleary, Bloomington, MN US
Patent application number | Description | Published |
---|---|---|
20100183298 | PASSIVE OPTICAL NETWORK PROTECTION SWITCHING - This disclosure relates to detection of optical fiber failure and implementation of protection switching in a passive optical network (PON). A protection switch determines whether there is an optical fiber failure in a fiber link between an OLT and a group of ONTs. In the case of an optical fiber failure, an optical fiber may be physically cut or damaged, causing the optical fiber link to be disabled. A protection switch may detect an optical fiber failure by determining a peak optical power of at least a portion of an upstream optical signal transmitted from one or more ONTs via the optical fiber link. If the peak optical power is less than a threshold value, the protection switch may detect a fiber failure. In response to a detected fiber failure, the protection switch may switch upstream and downstream PON transmissions from a primary optical fiber to a secondary optical fiber. | 07-22-2010 |
Dennis M. Cleary, Pittsford, NY US
Patent application number | Description | Published |
---|---|---|
20100278530 | DISTRIBUTED ANTENNA SYSTEM FOR WIRELESS NETWORK SYSTEMS - A distributed antenna system is provided for communicating with a plurality of base stations. The distributed antenna system includes a system controller and a master unit communicating with at least one of the plurality of base stations. A remote unit communicates over a high data rate media with the master unit and/or a downstream remote unit. Alternatively, the distributed antenna system includes a controller and a digital time/space crosspoint switch controlled by the controller. A digitizing transceiver is in communication with the digital time/space crosspoint switch. The crosspoint switch is configured to transmit and receive digital data through the digitizing transceiver. | 11-04-2010 |
20130308537 | DISTRIBUTED ANTENNA SYSTEM FOR WIRELESS NETWORK SYSTEMS - A distributed antenna system is provided for communicating with a plurality of base stations. The distributed antenna system includes a system controller and a master unit communicating with at least one of the plurality of base stations. A remote unit communicates over a high data rate media with the master unit and/or a downstream remote unit. Alternatively, the distributed antenna system includes a controller and a digital time/space crosspoint switch controlled by the controller. A digitizing transceiver is in communication with the digital time/space crosspoint switch. The crosspoint switch is configured to transmit and receive digital data through the digitizing transceiver. | 11-21-2013 |
Dillon C. Cleary, Middleboro, MA US
Patent application number | Description | Published |
---|---|---|
20160090397 | Se-Adenosyl-L-Selenohomocysteine Selenoxide As A Modulator Of Methyltransferase And Other Activities - The invention relates to a compound of the structural formula | 03-31-2016 |
Donald E. Cleary, Littleton, MA US
Patent application number | Description | Published |
---|---|---|
20080268138 | Metal plating compositions and methods - Disclosed are metal plating compositions and methods. The metal plating compositions provide good leveling performance and throwing power. | 10-30-2008 |
20080269395 | Metal plating compositions - Disclosed are metal plating compositions for plating a metal on a substrate. The metal plating compositions include compounds which influence the leveling and throwing performance of the metal plating compositions. Also disclosed are methods of depositing metals on a substrate. | 10-30-2008 |
20090188804 | Plating method - Methods for depositing a metal or metal alloy on a substrate and articles made with the methods are described. The metal or metal alloy is deposited on the substrate electrolytically. The current is periodically interrupted during deposition to improve throwing power and reduce nodule formation on the metal or metal alloy deposit. | 07-30-2009 |
20110318479 | METAL PLATING COMPOSITIONS AND METHODS - Disclosed are metal plating compositions and methods. The metal plating compositions provide good leveling performance and throwing power. | 12-29-2011 |
20120034371 | METAL PLATING COMPOSITIONS - Disclosed are metal plating compositions for plating a metal on a substrate. The metal plating compositions include compounds which influence the leveling and throwing performance of the metal plating compositions. Also disclosed are methods of depositing metals on a substrate. | 02-09-2012 |
20130230657 | STABLE CATALYSTS FOR ELECTROLESS METALLIZATION - Catalysts include nanoparticles of catalytic metal and gallic acid or gallic acid derivatives or salts thereof. The catalysts are used in electroless metal plating. The catalysts are free of tin. | 09-05-2013 |
20140081045 | METAL PLATING COMPOSITIONS AND METHODS - Disclosed are metal plating compositions and methods. The metal plating compositions provide good leveling performance and throwing power. | 03-20-2014 |
20150024123 | CATALYSTS FOR ELECTROLESS METALLIZATION CONTAINING IMINODIACETIC ACID AND DERIVATIVES - Catalysts include iminodiacetic acid and derivatives thereof as ligands for metal ions which have catalytic activity. The catalysts may be used to electrolessly plate metal on metal clad and un-clad substrates. | 01-22-2015 |
Donald E. Cleary, Marlborough, MA US
Patent application number | Description | Published |
---|---|---|
20160038925 | CATALYSTS FOR ELECTROLESS METALLIZATION CONTAINING FIVE-MEMBERED HETEROCYCLIC NITROGEN COMPOUNDS - Catalysts include five-membered nitrogen containing heterocyclic compounds as ligands for metal ions which have catalytic activity. The catalysts are used to electrolessly plate metal on metal clad and un-clad substrates. | 02-11-2016 |
Doreen Cleary, Mashpee, MA US
Patent application number | Description | Published |
---|---|---|
20090007911 | Pulmonary Rehabilitation Providing Respiratory Assistance by Application of Positive Airway Pressure - A system for pulmonary rehabilitation by the application of positive airway pressure, characterized in that the system comprises a source of pressurized air, a source of pressurized oxygen, control arrangement for enabling a control of the sources of pressurized air and pressurized oxygen, a source of sterile water, a source of heat, and an output arrangement for providing pressurized and heated air and oxygen to a patient. The system can be rendered portable by use of a mobile casing. Means can be provided for enabling an automatic following of a patient by the casing. | 01-08-2009 |
Earnest L. Cleary, Superior Township, MI US
Patent application number | Description | Published |
---|---|---|
20150145272 | REAR PASS THROUGH POWER OUTLET - A rear seat assembly within an automotive vehicle is provided. The seat assembly including a seat bottom portion and a seat back portion where the seat back portion includes a fold down arm rest movable from a closed position to an open position. The fold down arm rest is pivotable about a first pivot point. A generally vertical wall separates a cab portion of the vehicle from a trunk portion of the vehicle. The wall is connected to the seat back portion and is generally parallel with the seat back portion. A passageway or pass through portion connects the cab portion of the vehicle with the trunk portion of the vehicle. A power supply portion is mounted to the generally vertical wall and is mounted adjacent to or within the passageway. The power supply portion is accessible when the fold down arm rest is in the open position. | 05-28-2015 |
Geoffrey Alan Cleary, Ambler, PA US
Patent application number | Description | Published |
---|---|---|
20080301226 | LOW COST, HIGHLY ACCURATE VIDEO SERVER BIT-RATE COMPENSATION - A method, apparatus and system for adaptably distributing video server processes among processing elements within a video server such that video server operation may be adapted in a manner facilitating rigorous timing constraints. | 12-04-2008 |
Gregory Cleary, Dayton, OH US
Patent application number | Description | Published |
---|---|---|
20130166628 | TRANSACTION SERVICES MANAGEMENT SYSTEM - One or more network devices send to a user device a user interface with options for configuring a network to provide transaction services between transaction devices and host processing devices. The user interface is accessible to the user device via a private network connection. The one or more network devices receive from the user device configuration settings for a particular host processing device. The one or more network devices store the configuration settings in a database of transaction services data for multiple host processing devices, to be accessed by another device within the network for configuring the network for the particular host processing device. | 06-27-2013 |
20130167047 | TRANSACTION SERVICES REPORTING SYSTEM - One or more devices within a transaction services hub collect session data of transaction services for multiple customers and provide a user interface with reporting options for transaction services associated with a particular customer. The user interface is accessible to a user device via a public network connection. The one or more devices receive a report request from a user account associated with the particular customer and retrieve, from the collected session data, data responsive to the report request. The one or more devices generate a report for the particular customer based on the report request and the data responsive to the report request. | 06-27-2013 |
Jay Cleary, New York, NY US
Patent application number | Description | Published |
---|---|---|
20100169193 | Conversion engine and financial reporting system using the conversion engine - A computerized management system is provided. The system includes a routine for accessing journal entries stored in a memory and an automated journal entry generating routine for generating journal entries for a first set-of-books and for a second set-of-books based on the accessed journal entries. The journal entries for the first set-of-books are in accordance with a first reporting standard and the journal entries for the second set-of-books are in accordance with a second, different reporting standard. | 07-01-2010 |
John D. Cleary, Brandon, MS US
Patent application number | Description | Published |
---|---|---|
20110152211 | METHODS AND FORMULATIONS FOR REDUCING AMPHOTERICIN B TREATMENT SIDE EFFECTS - A method of ameliorating amphotericin treatment side effects in a mammal that comprises administering a therapeutically effective amount of a formulation that comprises a polyene active ingredient that includes amphotericin B, wherein the amphotericin B compound is present, in terms of polyene content, in an amount greater than 90%, and non-amphotericin B polyene compounds are present in an amount of no greater than 10%, and a pharmaceutically effective carrier; and administering a therapeutically effective amount of said formulation to a subject in need thereof. | 06-23-2011 |
John M. Cleary, New Fairfield, CT US
Patent application number | Description | Published |
---|---|---|
20100255198 | SOLID PRECURSOR-BASED DELIVERY OF FLUID UTILIZING CONTROLLED SOLIDS MORPHOLOGY - Apparatus and method for volatilizing a source reagent susceptible to particle generation or presence of particles in the corresponding source reagent vapor, in which such particle generation or presence is suppressed by structural or processing features of the vapor generation system. Such apparatus and method are applicable to liquid and solid source reagents, particularly solid source reagents such as metal halides, e.g., hafnium chloride. The source reagent in one specific implementation is constituted by a porous monolithic bulk form of the source reagent material. The apparatus and method of the invention are usefully employed to provide source reagent vapor for applications such as atomic layer deposition (ALD) and ion implantation. | 10-07-2010 |
20140329025 | SOLID PRECURSOR-BASED DELIVERY OF FLUID UTILIZING CONTROLLED SOLIDS MORPHOLOGY - Apparatus and method for volatilizing a source reagent susceptible to particle generation or presence of particles in the corresponding source reagent vapor, in which such particle generation or presence is suppressed by structural or processing features of the vapor generation system. Such apparatus and method are applicable to liquid and solid source reagents, particularly solid source reagents such as metal halides, e.g., hafnium chloride. The source reagent in one specific implementation is constituted by a porous monolithic bulk form of the source reagent material. The apparatus and method of the invention are usefully employed to provide source reagent vapor for applications such as atomic layer deposition (ALD) and ion implantation. | 11-06-2014 |
20150191819 | SOURCE REAGENT-BASED DELIVERY OF FLUID WITH HIGH MATERIAL FLUX FOR BATCH DEPOSITION - Systems, reagent support trays, particle suppression devices, and methods are disclosed. In one aspect, a system includes a vaporizer vessel having one or more interior walls enclosing an interior volume and a plurality of reagent support trays configured to be vertically stackable within the interior volume. Each of the plurality of reagent support trays is configured to be vertically stackable within the interior volume to form a stack of reagent support trays. One or more of the plurality of reagent support trays is configured to redirect a flow of a gas passing between adjacent reagent support trays in the stack of reagent support trays to cause the flow of gas to interact with the source reagent material in a particular reagent support tray before passing into a next of the plurality of reagent support trays in the stack of reagent support trays. | 07-09-2015 |
Joseph A. Cleary, Dodgeville, WI US
Patent application number | Description | Published |
---|---|---|
20120140219 | Monolithic Geared Optical Reflector - A novel monolithic geared optical reflector apparatus which is configured from a gear blank machined to have an integral shaft and integral reflective surface with desired optical properties is introduced herein. Such a rotating mirror device is beneficially capable of being configured into any optical instrument, such as, but not limited to a spectrophotometer, wherein the reflector is adapted to accurately point to a plurality of locations within or out of the system via gear to gear rotation. | 06-07-2012 |
Joseph Gordon Cleary, Bethlehem, PA US
Patent application number | Description | Published |
---|---|---|
20100130923 | APPARATUS AND METHOD FOR INSERTING A CATHETER - A delivery apparatus for a stimulating catheter has a conductive wire wound within a reel dispenser. The reel dispenser has a base portion and a rotating portion that are coupled at the axle with the rotating portion rotatable relative to the base portion. The proximal region of the conductive wire is in electrical connection with the axle of the dispenser. A method for delivering a stimulating catheter includes introducing the distal regions of the conductive wire and catheter into a subject, rotating the rotating portion of the reel dispenser relative to the base portion whereby the catheter and conductive wire are advanced into the subject, providing an electrical current to the conductive wire through the axle, and rewinding the rotating portion of the reel dispenser relative to the base portion whereby the conductive wire is retracted in a proximal direction through the catheter. | 05-27-2010 |
Joseph M. Cleary, Cold Spring, KY US
Patent application number | Description | Published |
---|---|---|
20080300730 | Roller-ball roller coaster - A novel roller coaster comprising a spherical, rotating rider-enclosure, wherein the roller coaster is transported along or within a track configured to transport the coaster, while converting coaster kinetic energy from potential energy and back. The rider is subjected to accelerations resulting from the coaster's transport, among which are rotational accelerations resulting from the rider enclosure. In a preferred embodiment, the coaster comprises a transport mechanism, the transport mechanism engaging and following a track. The spherical enclosure further includes a gimbal arrangement having a gyroscope, the gimbal arrangement supported by the transport mechanism. The gimbal arrangement contains at least one seat carrying a rider, and the motion of the rider is determined by the gyroscope that is controlled by a computer within the coaster. Therefore the motion of the rider is determined by the path of the transport mechanism and the rotation of the rider compartment under the computer controlled gyroscope. The spherical enclosure may roll within a track or the spherical enclosure may be attached to and carried by a traditional roller coaster conveyance. | 12-04-2008 |
Katherine Cleary, Cedar Knolls, NJ US
Patent application number | Description | Published |
---|---|---|
20100303991 | HIGH FIBER AND HIGH PROTEIN BAKED GOODS PRODUCTION - Substantially uniform hydration and dispersion of high amounts of protein and fiber are achieved while avoiding lump formation, hard textures, and off-tastes in the continuous, mass production of high protein and high fiber content sheetable doughs, and baked goods such as crackers, snacks, and cookies made from the sheeted doughs, by hydrating the protein and fiber with water at a temperature below the denaturization temperature of the proteins, and steaming the hydrated mixture without substantial gelatinization of starch during dough production. The steamed, hydrated mass may be admixed with ingredients comprising at least one flour comprising starch to obtain a dough while avoiding substantial gelatinization of starch of the at least one flour during mixing. The baked goods may have a protein content of at least about 4 g, a fiber content of at least about 4 g, and a whole grain flour content of at least about 4 g per 30 g serving. | 12-02-2010 |
Kevin Cleary, Washington, DC US
Patent application number | Description | Published |
---|---|---|
20140371584 | PATIENT MOUNTED MRI AND CT COMPATIBLE ROBOT FOR NEEDLE GUIDANCE IN INTERVENTIONAL PROCEDURES - A patient mountable robot includes a four link mechanism, three actuators, and a first robot base. The mechanism includes four links that form a closed loop structure. The four links include a base link that includes a spherical joint. The mechanism provides two rotational degrees of freedom about the spherical joint for a needle that is configured to pass through the spherical joint. A first actuator is attached to the mechanism and moves the mechanism to provide the first of the two rotational degrees of freedom. A second actuator is attached to the mechanism and moves the mechanism to provide the second of the two rotational degrees of freedom. The base link of the mechanism passes through the first robot base. A third actuator is attached to the first robot base and linearly translates the base link so that a translational degree of freedom is provided for the needle. | 12-18-2014 |
Kevin Cleary, Potomac, MD US
Patent application number | Description | Published |
---|---|---|
20130123580 | ENHANCED CONTROL OF FLEXIBLE ENDOSCOPES THROUGH HUMAN-MACHINE INTERFACE - An electromechanical drive system with drop-in capability allows manipulation of the majority of existing endoscopes. The invention does not require retrofitting of existing endoscopes and maintains the current clinical workflow. The drive system can be controlled through a human/machine interface, which could consist of a variety of different input devices, including a joystick, keyboard, or game controller. | 05-16-2013 |
20150223956 | ANCHORED NON-SPHERICAL BALLOON FOR THE TREATMENT OF OBESITY - Described herein are a device and an associated method for treatment of obesity. Specifically, a non-spherical balloon is described that expands inside the stomach to reduce luminal volume. The non-spherical balloon is firmly anchored to the abdominal wall in order to eliminate migration risks. Further, the device inflates in a longitudinal fashion to fill a greater curvature of the stomach, thereby preventing food from contacting the ghrelin-producing cells that stimulate hunger. | 08-13-2015 |
20160038002 | ENHANCED CONTROL OF FLEXIBLE ENDOSCOPES THROUGH HUMAN-MACHINE INTERFACE - An electromechanical drive system with drop-in capability allows manipulation of the majority of existing endoscopes. The invention does not require retrofitting of existing endoscopes and maintains the current clinical workflow. The drive system can be controlled through a human/machine interface, which could consist of a variety of different input devices, including a joystick, keyboard, or game controller. | 02-11-2016 |
Mark James Cleary, Powder Springs, GA US
Patent application number | Description | Published |
---|---|---|
20090071163 | SYSTEMS AND METHODS FOR INSTALLING COOLING HOLES IN A COMBUSTION LINER - A system and method for modification of cooling holes in a combustion liner to prevent cracking. The invention provides a portable combustion liner modification system for a gas turbine able to allow for the correct placement of cooling holes on the combustion liner preventing cracks from forming around the mixing hole. | 03-19-2009 |
Martin Cleary, Waltham, MA US
Patent application number | Description | Published |
---|---|---|
20150270465 | NbFeSb-Based Half-Heusler Thermoelectric Materials and Methods of Fabrication and Use - A thermoelectric half-Heusler material comprising niobium (Nb), iron (Fe) and antimony (Sb) wherein the material comprises grains having a mean grain size less than one micron. A method of making a nanocomposite half-Heusler thermoelectric material includes melting constituent elements of the thermoelectric material to form an alloy of the thermoelectric material, comminuting (e.g., ball milling) the alloy of the thermoelectric material into nanometer scale mean size particles, and consolidating the nanometer size particles to form the half-Heusler thermoelectric material comprising at least niobium (Nb), iron (Fe) and antimony (Sb) and having grains with a mean grain size less than one micron. | 09-24-2015 |
Michael Cleary, Jamison, PA US
Patent application number | Description | Published |
---|---|---|
20110166200 | METHODS OF USING MIR210 AS A BIOMARKER FOR HYPOXIA AND AS A THERAPEUTIC AGENT FOR TREATING CANCER - The present invention provides compositions and methods for predicting the hypoxia response in tumor cells, methods for predicting the likelihood of cancer metastasis, and methods for inhibiting tumor cell proliferation using a microRNA comprising miR-210. | 07-07-2011 |
Michael Alan Cleary, Lexington, KY US
Patent application number | Description | Published |
---|---|---|
20150110534 | Backup Roll Having Axial Constraints and Fuser Therefor - A fuser assembly for an imaging device is shown and described. The fuser assembly includes a heat transfer member for generating heat and a backup roll coupled to the heat transfer member and rotatable therewith. The backup roll includes a central core and a rubber layer surrounding the central core. The fuser assembly further includes a plurality of end cap members, each end cap member being disposed at an end of the backup roll and dimensioned for substantially preventing outward expansion of the rubber layer in an axial direction of the backup roll. | 04-23-2015 |
Michael F. Cleary, Vancouver, WA US
Patent application number | Description | Published |
---|---|---|
20100003390 | METHOD FOR ADDING FUNCTIONAL COMPONENTS TO HYDROCOLLOID BASES THAT REQUIRE COOKING - Functional components are often cooked with hydrocolloid bases to create a more palatable and nutritional product. Mixing the functional components and hydrocolloid base together and cooking the mixture often results in damage to the functional components. The damage caused to the functional components result in a reduction in the potency of the functional components or may otherwise adversely affect the functional components. Conversely, adding the functional components to the hydrocolloid base after the base has been cooked and cooled minimizes the damage caused to the functional components. | 01-07-2010 |
Michael J. Cleary, Hinsdale, IL US
Patent application number | Description | Published |
---|---|---|
20120254004 | Method and System for Distribution of Unactivated Bank Account Cards - The invention comprises a method for distributing dead bank cards to customers who have not solicited a bank card or submitted an application. The dead bank card is a bank card (e.g., ATM card, debit card, check card, and the like) which contains all necessary information to be used, including a pre-assigned bank account number, and which only requires activation/approval by the prospective new bank account customer. In one embodiment, the dead bank card is distributed in connection with live credit cards issued to applicants for credit card accounts. Once operative, the bank card and the credit card may be linked together through a rebate/rewards program. | 10-04-2012 |
20130238486 | METHOD AND SYSTEM FOR DISTRIBUTION OF UNACTIVATED BANK ACCOUNT CARDS - The invention comprises a method for distributing dead bank cards to customers who have not solicited a bank card or submitted an application. The dead bank card is a bank card (e.g., ATM card, debit card, check card, and the like) which contains all necessary information to be used, including a pre-assigned bank account number, and which only requires activation/approval by the prospective new bank account customer. In one embodiment, the dead bank card is distributed in connection with live credit cards issued to applicants for credit card accounts. Once operative, the bank card and the credit card may be linked together through a rebate/rewards program. | 09-12-2013 |
20130246153 | METHOD AND SYSTEM FOR DISTRIBUTION OF UNACTIVATED BANK ACCOUNT CARDS - The invention comprises a method for distributing dead bank cards to customers who have not solicited a bank card or submitted an application. The dead bank card is a bank card (e.g., ATM card, debit card, check card, and the like) which contains all necessary information to be used, including a pre-assigned bank account number, and which only requires activation/approval by the prospective new bank account customer. In one embodiment, the dead bank card is distributed in connection with live credit cards issued to applicants for credit card accounts. Once operative, the bank card and the credit card may be linked together through a rebate/rewards program. | 09-19-2013 |
Michael L. Cleary, Eugene, OR US
Patent application number | Description | Published |
---|---|---|
20140323524 | Anti-Proliferative Compounds and Methods for Using the Same - Disclosed herein are anti-proliferative compounds which find use in inhibiting the growth of cancer cells. Also provided herein are methods for using these compounds for inhibiting growth of cancer cells. Also provided herein are methods for using these compounds for treating a subject for hyperproliferative conditions, including without limitation the treatment of hematopoietic cancers. | 10-30-2014 |
Michael Martin Cleary, Longmont, CO US
Patent application number | Description | Published |
---|---|---|
20140353306 | Thermal Containers - A container to keep substances heated for longer periods of time is described. The container bears a cavity that contains a heating medium and a microwave susceptor. The container maybe a plate, cup, mug or other utensil to keep food or bevarages hot. | 12-04-2014 |
Michael Patrick Cleary, Denver, CO US
Patent application number | Description | Published |
---|---|---|
20120273213 | MARINE SUBSEA RISER SYSTEMS AND METHODS - A riser system connects a subsea source of hydrocarbons to a collection vessel. The system includes a riser, a lower end of the riser fluidly coupled to a seal stem, the seal stem in turn fluidly attached to a lower riser assembly through a polished bore receptacle. The upper end of the riser is connected to the collection vessel, the riser being maintained in a near vertical position. Methods of installing and using the riser systems for killing and cementing wells are described. | 11-01-2012 |
Michele Cleary, Rochester, NY US
Patent application number | Description | Published |
---|---|---|
20100092219 | FUSER APPARATUS HAVING FUSER CLEANER WEB AND CORRESPONDING METHODS - Disclosed are methods of controlling a speed of a fuser cleaner web in a fuser apparatus, and the corresponding fuser apparatus. The method utilizes a fuser cleaner web for cleaning a fuser roll and being disposed between the fuser roll and a web nip roll, the fuser cleaner web being unwound from a web supply roll and wound onto a take up roll, the take up roll being driven by a motor. The method determines an angular displacement of the motor from a start of the fuser cleaner web being unwound from the web supply roll, and controls a speed of the motor to maintain a substantially constant fuser cleaner web speed, wherein the speed of the motor is controlled based on the determined angular displacement of the motor and a changing diameter of the take up roll, the changing diameter of the take up roll including a diameter of the fuser cleaner web as it is wound onto the take up roll. | 04-15-2010 |
Michele A. Cleary, Jamison, PA US
Patent application number | Description | Published |
---|---|---|
20100227909 | COMPOSITIONS COMPRISING MIR34 THERAPEUTIC AGENTS FOR TREATING CANCER - In one aspect, the invention generally relates to compositions comprising miR-34 and siRNAs functionally and structurally related to miR-34 for the treatment of cancer. | 09-09-2010 |
20110105583 | METHODS OF USING MIR34 AS A BIOMARKER FOR TP53 FUNCTIONAL STATUS - In one aspect, the invention generally relates to use of miR-34 as a biomarker to estimate TP53 function in a cell. In another aspect, the invention generally relates to multiple uses of miR-34 and siRNAs functionally and structurally related to miR-34 for the treatment of cancer. | 05-05-2011 |
20120149602 | METHOD FOR MAKING POPULATIONS OF DEFINED NUCLEIC ACID MOLECULES - The present invention provides methods of making a population of nucleic acid molecules, wherein each nucleic acid molecule comprises a predetermined nucleic acid sequence, each of said methods comprising the steps of: (a) synthesizing, on a substrate, a population of nucleic acid molecules wherein: i) each synthesized nucleic acid molecule comprises a predetermined nucleic acid sequence; and ii) each synthesized nucleic acid molecule is localized to a defined area of said substrate; (b) harvesting said population of synthesized nucleic acid molecules from said substrate to yield harvested nucleic acid molecules; and (c) introducing said harvested nucleic acid molecules into vector molecules. | 06-14-2012 |
Michele A. Cleary, Bothell, WA US
Patent application number | Description | Published |
---|---|---|
20090136957 | Methods and compositions for regulating cell cycle progression via the miR-106B family - In one aspect, a method is provided of inhibiting proliferation of a mammalian cell comprising introducing into said cell an effective amount of at least one microRNA-specific inhibitor of at least one miR-106b family member. In another aspect a method is provided for accelerating proliferation of a mammalian cell comprising introducing into said cell an effective amount of at least one miR-106b family member. | 05-28-2009 |
20100113287 | METHODS FOR ASSESSING THE REPRESENTATION OF NUCLEIC ACID MOLECULES IN A NUCLEIC ACID LIBRARY - The invention provides methods for evaluating the representation of expected nucleic acid molecules in a test population of nucleic acid molecules. The methods each comprise the steps of: (a) hybridizing a population of sample nucleic acid molecules obtained from a test population of nucleic acid molecules to a substrate comprising a population of target nucleic acid molecules, wherein (i) each target nucleic acid molecule comprises a predetermined sequence corresponding to an expected nucleic acid molecule, and (ii) each target nucleic acid molecule is localized to a defined area of the substrate; and (b) evaluating the representation of expected nucleic acid molecules in the test population of nucleic acid molecules by analyzing the pattern of hybridization of the sample population of nucleic acid molecules to the target nucleic acid molecules. | 05-06-2010 |
Michele D. Cleary, Rochester, NY US
Patent application number | Description | Published |
---|---|---|
20080217838 | METHOD OF CONTROLLING ENVIRONMENT WITHIN MEDIA FEED STACK - A method maintains an environment within an interior of a sheet feeder during dead-cycling of an image forming device to which the sheet feeder is operatively connected. The method jets pulses of air into the interior of the sheet feeder that houses two or more pieces of media therein while the image forming device is dead-cycling. By the method, the attractive forces between two pieces of adjacent media. In a stack are reduced or minimized, and feeding of multiple sheets can be reduced or eliminated. | 09-11-2008 |
20130114985 | CONTROLLING EXIT VELOCITY OF PRINTED SHEETS BEING STACKED TO OPTIMIZE STACK QUALITY - Methods and devices determine the media properties of a sheet of media exiting a printing device. The methods and devices apply the media properties to a predetermined velocity equation to calculate a corresponding sheet exit velocity for the sheet of media that will optimize stack quality in a particular output tray. Then, the methods and devices change process controls sheet movement elements within a media path of the printing device to cause the sheet of media to exit the printing device at the sheet exit velocity. | 05-09-2013 |
20130279929 | INFERRING TONER CONTAMINATION OF ELECTRODES FROM PRINTING PARAMETERS - A computer implemented method of cleaning electrodes (such as wires) is used in a toner-based electrostatic printing device. The electrodes produce an environment containing charged toner particles to assist in electrostatic printing. The method automatically monitors at least two printing parameters that are unrelated to signals and voltages provided to the electrodes (using a processor of the electrostatic printing device). Further, this method also uses the processor automatically infers a toner contamination of the electrodes from the printing parameters. This allows the processor to automatically adjust the printing the used by the electrostatic printing device during electrostatic printing to maintain the contamination of the electrodes below a threshold. | 10-24-2013 |
Michele Donna Cleary, Rochester, NY US
Patent application number | Description | Published |
---|---|---|
20100044955 | APPARATUS AND METHOD FOR CONTROLLING FEED COMMITMENTS BASED ON FEEDABLE CAPACITY | 02-25-2010 |
20110243629 | Process For Preparing Braille Images Using Inline Digital Coating - A method for forming Braille images on a substrate comprising feeding a substrate to an inline digital coating apparatus; forming one or more Braille images on the substrate with the inline digital coating apparatus; wherein the inline digital coating apparatus forms the Braille image by coating an ultra-violet curable phase change ink composition comprising an optional colorant and a phase change ink vehicle comprising a radiation curable monomer or prepolymer; a photoinitiator; a reactive wax; and a gellant in a single pass to form the one or more Braille images; and curing the one or more Braille images. | 10-06-2011 |
Pamela A. Cleary, King Of Prussia, PA US
Patent application number | Description | Published |
---|---|---|
20080293720 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors - The present invention relates to compounds of following formula: | 11-27-2008 |
Paul Patrick Cleary, St. Paul, MN US
Patent application number | Description | Published |
---|---|---|
20140037669 | MULTICOMPONENT IMMUNOGENIC COMPOSITION FOR THE PREVENTION OF BETA-HEMOLYTIC STREPTOCOCCAL (BHS) DISEASE - A number of β-hemolytic streptococci polynucleotides and polypeptides, particularly | 02-06-2014 |
Peter Cleary, Pembroke, MA US
Patent application number | Description | Published |
---|---|---|
20150025940 | SYSTEMS AND METHODS FOR GENERATING CUSTOMER SOLUTIONS - Implementations described and claimed herein provide systems and methods for generating customer solutions using real-time information for new customer sales and/or current customer support. In one implementation, technical infrastructure information for an installed network design providing one or more telecommunication products at one or more customer sites is retrieved. Customer service analytics are generated based on the technical infrastructure information and output for display on a graphical user interface. | 01-22-2015 |
20150026073 | SYSTEMS AND METHODS FOR GENERATING CUSTOMER SOLUTIONS - Implementations described and claimed herein provide systems and methods for generating customer solutions using real-time information for new customer sales and/or current customer support. In one implementation, technical infrastructure data for a provider network is retrieved from one or more databases. The technical infrastructure data represents network assets and capabilities. Location information is obtained for at least one customer site. A product selection including a set of design attributes for one or more telecommunication products is received. A network access point for providing the one or more telecommunication products is determined based on a correlation of the technical infrastructure data with the location information. A configuration for the at least one customer site is generated based on the product selection. A design is generated based on the network access point and the at least one configured customer site. | 01-22-2015 |
Peter W. Cleary, Colorado Springs, CO US
Patent application number | Description | Published |
---|---|---|
20150163206 | CUSTOMIZABLE SECURE DATA EXCHANGE ENVIRONMENT - In embodiments, the disclosure provides a secure data exchange system that includes a data management facility; and a plurality of data storage nodes. The data management facility manages content sharing between entities of data stored in the data storage nodes, wherein the data is stored by a user of a first entity and comprises content and metadata. The data management facility only has access to the metadata of the user data for managing of the data in the plurality of data storage nodes and not the content. The data management facility may be geographically distributed at a plurality of data management sites and the data storage nodes may exist inside and outside of a firewall of the first entity. | 06-11-2015 |
20150310188 | SYSTEMS AND METHODS OF SECURE DATA EXCHANGE - In embodiments of the present invention improved capabilities are described for managing digital rights management (DRM) protected content sharing in a networked secure collaborative computer data exchange environment through a secure exchange facility managed by an intermediate organizational entity amongst users of a plurality of other organizational entities, wherein computer data content and access rights for the computer data content is shared between a first and second user, the computer data content and access rights for the computer data content are transformed into a DRM protected computer data content through communications with a DRM engine, wherein the DRM engine is selected based on a content type of the computer data content, and the DRM engine is provided by an entity other than the intermediate organizational entity and other than any of the plurality of other organizational entities. | 10-29-2015 |
Robert R. Cleary, Pearland, TX US
Patent application number | Description | Published |
---|---|---|
20120212729 | THERMAL PHASE SEPARATION SIMULATOR - A thermal phase separation simulator and method for testing chemicals is disclosed. The simulator comprises a circular block heater carousel mounted for rotation on a stage. The carousel includes a circular array of test wells for receiving a plurality of test bottles, a plurality of heating elements and thermocouples disposed between the wells. Each well has an illumination port and a vertical slit to the outside to allow visual observation or imaging of a vertical swatch of the bottle. An illumination source aligns with the illumination port of each well in response to rotation of the carousel. The method includes adding a mixed phase fluid to a plurality of bottles, adding a chemical agent to each bottle, and simulating a thermal phase separation. Images of the fluid in each bottle are captured and analyzed to determine the performance of the one or more chemical agents. | 08-23-2012 |
Stephen Cleary, Baltimore, MD US
Patent application number | Description | Published |
---|---|---|
20120121210 | Bag with Cover - A bag includes an outer body portion or outer shell which encloses a storage compartment. The bag also includes a pocket non-removably attached to the bag which is accessible through the outer body portion or outer shell and is freely contained within the storage compartment. The pocket is configured to retain a cover, which is non-removably attached thereto. The cover is a flexible material that is water resistant or water repellant. The cover can be collapsed and stored within the pocket or can be withdrawn from the pocket and spread over the outer body portion or outer shell of the bag, thereby protecting it, for example, from inclement weather. | 05-17-2012 |
Stephen Cleary, Severna Park, MD US
Patent application number | Description | Published |
---|---|---|
20120093685 | Article with Deodorant Device - An article configured to be worn or carried by a human includes a body portion with a deodorant enclosure and a deodorant insert positioned within the deodorant enclosure. The body portion is comprised of a flexible material that defines an inside and an outside of the article. An opening is formed in the body portion which provides a passage between the inside and the outside of the article. The deodorant enclosure is secured to the body portion at the opening. The deodorant enclosure includes a chamber positioned between an air permeable inner wall and an air permeable outer wall. The deodorant insert is removably positioned within the chamber of the deodorant enclosure. | 04-19-2012 |
20130221049 | BAG WITH VARIABLE DIAMETER CORDING - An apparatus for carrying objects includes a bag and at least one cord. The bag has a top portion and a bottom portion. The top portion of the bag includes a channel. The cord includes a first end portion coupled to the bottom portion of the bag, a second end portion coupled to the bottom portion of the bag, and a middle portion positioned between the first end portion and the second end portion. The middle portion of the cord includes a first length of cord which extends slidably through the channel and a second length of cord which is positioned outside of the channel. The second length of cord has a substantially larger diameter than the first length of cord. | 08-29-2013 |
20140355908 | BAG WITH ADJUSTABLE MOUTH AND VARIABLE DIAMETER CORDING - An apparatus for carrying objects includes a bag and at least one cord. The bag has a top portion and a bottom portion. The top portion of the bag includes an adjustable mouth and a channel. The cord includes a first end portion coupled to the bottom portion of the bag, a second end portion coupled to the bottom portion of the bag, and a middle portion positioned between the first end portion and the second end portion. The middle portion of the cord includes a first length of cord which extends slidably through the channel and a second length of cord which is positioned outside of the channel. The second length of cord has a substantially larger diameter than the first length of cord. | 12-04-2014 |
Terrance Cleary, Fond Du Lac, WI US
Patent application number | Description | Published |
---|---|---|
20130248058 | Heat Treatment Process for Engine Ring Gear - The present disclosure relates to methods of hardening toothed gear parts for engines. The method results in a uniformly hardened gear with minimized distortion. | 09-26-2013 |
Terrance M. Cleary, Fond Du Lac, WI US
Patent application number | Description | Published |
---|---|---|
20140271342 | NICKEL CONTAINING HYPEREUTECTIC ALUMINUM-SILICON SAND CAST ALLOY - A nickel containing hypereutectic aluminum-silicon sand cast alloy is disclosed herein containing 18-20% by weight silicon, 0.3-1.2% by weight magnesium, 3.0-6.0% by weight nickel, 0.6% by weight maximum iron, 0.4% by weight maximum copper, 0.6% by weight maximum manganese, 0.1% maximum zinc and balance aluminum. The alloy may have a more narrow nickel content of 4.5%-6.0% by weight, and up to 2% by weight cobalt. The alloy may be substantially free from iron, copper and manganese. The alloy of the present invention is preferably sand cast, and most preferably lost foam cast with a pressure of 10 ATM to produce engine parts with high thermal properties that are easily machined. | 09-18-2014 |
Thomas Cleary, Florence, SC US
Patent application number | Description | Published |
---|---|---|
20080312288 | SOLID FORMS OF 2-CHLORO-4-[1-(4-FLUORO-PHENYL)-2,5-DIMETHYL-1H-IMIDAZOL-4-YLETHYNYL]-PYRIDINE - The present invention relates to the mono-sulfate salt, crystalline forms A and B of the mono-sulfate salt, an amorphous form of the mono-sulfate salt, hemi-sulfate salts, and a crystalline form A of the hemi-sulfate salt of the compound 2-chloro-4-[1-(4-fluoro-phenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]-pyridine. | 12-18-2008 |
20080312467 | NOVEL PROCESS FOR THE PREPARATION OF 3-AMINO-PENTAN-1,5-DIOL - The present invention provides a novel method for preparing a key intermediate, 3-amino-pentan-1,5-diol (2), which is useful for the preparation of 6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)-propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidine-7-one (1) a MAP-kinase inhibitor useful in the treatment of rheumatoid arthritis. | 12-18-2008 |
20100094011 | DIAZONIUM-FREE METHOD TO MAKE AN INDAZOLE INTERMEDIATE IN THE SYNTHESIS OF BICYCLIC 5-(TRIFLUORMETHOXY)-1H-3-INDAZOLECARBOXYLIC ACID AMIDES - The present invention provides novel methods for preparing 5-(trifluoromethoxy)-1H-3-indazolecarboxylic acid (3), which is a useful precursor for the preparation of bicyclic-5-trifluoromethoxy-1H-indazole-3-carboxylic acid amides of Formula (1). Compounds of Formula (1) are active as agonists and partial agonists of the nicotinic α-7 receptor and are being studied for their use in the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain, such as for the treatment of Alzheimer's disease and schizophrenia, as well as other psychiatric and neurological disorders. The present methods are useful for preparing compound (3) on scale up levels. | 04-15-2010 |
20120035222 | Solid forms of 2-Chloro-4-[1-(4-fluoro-phenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]-pyr- idine - The present invention relates to mono-sulfate and hemi-sulfate salts of 2-Chloro-4-[1-(4-fluoro-phenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]-pyridine, to crystalline and amorphous forms thereof and to their use in pharmaceutical formulations. | 02-09-2012 |
20120259120 | DIAZONIUM-FREE METHOD TO MAKE AN INDAZOLE INTERMEDIATE IN THE SYNTHESIS OF BICYCLIC 5-(TRIFLUORMETHOXY)-1H-3-INDAZOLECARBOXYLIC ACID AMIDES - The present invention provides novel methods for preparing 5-(trifluoromethoxy)-1H-3-indazolecarboxylic acid (3), which is a useful precursor for the preparation of bicyclic-5-trifluoromethoxy-1H-indazole-3-carboxylic acid amides of Formula (1). Compounds of Formula (1) are active as agonists and partial agonists of the nicotinic α-7 receptor and are being studied for their use in the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain, such as for the treatment of Alzheimer's disease and schizophrenia, as well as other psychiatric and neurological disorders. The present methods are useful for preparing compound (3) on scale up levels. | 10-11-2012 |
Thomas J. Cleary, St. Louis County, MO US
Patent application number | Description | Published |
---|---|---|
20140209086 | DIRECT FIRED HEATERS INCLUDING PREMIX BURNER TECHNOLOGY - According to various aspects, exemplary embodiments are disclosed of direct fired heaters including premix burner technology and/or feed forward control loop modulation via inlet air temperature. | 07-31-2014 |
Thomas Joseph Cleary, Kirkwood, MO US
Patent application number | Description | Published |
---|---|---|
20150362213 | BLOW THROUGH DIRECT FIRED HEATING, A/C AND ERV - According to various aspects, exemplary embodiments are disclosed of blow through direct fired heaters including evaporator coils and/or energy recovery ventilation. | 12-17-2015 |
Thomas M. Cleary, Elmira, NY US
Patent application number | Description | Published |
---|---|---|
20120328843 | LIGHT-WEIGHT HYBRID GLASS LAMINATES - A glass laminate comprises an external glass sheet, an internal glass sheet, and a polymer interlayer formed between the external glass sheet and the internal glass sheet. The external glass sheet is a chemically-strengthened glass sheet having a thickness of less than 1 mm, the polymer interlayer has a thickness of less than 1.6 mm, and the internal glass sheet is a non-chemically-strengthened glass sheet having a thickness of less than 2.5 mm. | 12-27-2012 |
20130319046 | APPARATUS FOR SHAPING GLASS AND METHODS - An apparatus for shaping a glass sheet includes an engagement member including a flexible bumper comprising a flexible material. The flexible bumper is configured to operate at the forming temperature to reduce an impact stress between the engagement member and the edge portion of the glass sheet. In another example, an apparatus for shaping a sheet of glass includes a push member configured to engage an end edge portion of the glass sheet to push the glass sheet to be transported over the support surface. The push member includes a push flange extending in a direction away from the support surface. The push flange includes a plurality of apertures configured to increase the resistance of conductive heat transfer between the end edge portion of the glass sheet and the push member. In a further example an engagement member can fabricated from a material having a coefficient of thermal conductivity that is less than a coefficient of thermal conductivity of the stainless steel. In further examples, methods include using the apparatus to shape a glass sheet. | 12-05-2013 |
Thomas Michael Cleary, Elmira, NY US
Patent application number | Description | Published |
---|---|---|
20130295357 | LIGHT-WEIGHT HYBRID GLASS LAMINATES - A glass laminate comprises an external glass sheet, an internal glass sheet, and a polymer interlayer formed between the external glass sheet and the internal glass sheet. The external glass sheet can be a thin chemically-strengthened glass sheet or can be a non-chemically strengthened glass sheet, the polymer interlayer can have a thickness of less than 1.6 mm, and the internal glass sheet can be a non-chemically-strengthened glass sheet or a thin chemically strengthened glass sheet. | 11-07-2013 |
20140087159 | METHODS FOR PRODUCING ION EXCHANGED GLASS AND RESULTING APPARATUS - A laminate structure having a first glass layer, a second glass layer, and at least one polymer interlayer intermediate the first and second glass layers. The first glass layer is comprised of a thin, chemically strengthened glass having a surface compressive stress of between about 250 MPa and about 350 MPa and a depth of layer (DOL) of compressive stress greater than about 60 μm. The second glass layer can also be comprised of a thin, chemically strengthened glass having a surface compressive stress of between about 250 MPa and about 350 MPa and a depth of layer (DOL) of compressive stress greater than about 60 μm. | 03-27-2014 |
20140087193 | METHODS FOR PRODUCING ION EXCHANGED GLASS AND RESULTING APPARATUS - Methods and apparatus provide for performing an ion exchange process by immersing a glass sheet into a molten salt bath at one or more first temperatures for a first period of time such that ions within the glass sheet proximate to a surface thereof are exchanged for larger ions from the molten salt bath, thereby producing: (i) an initial compressive stress (iCS) at the surface of the glass sheet, (ii) an initial depth of compressive layer (iDOL) into the glass sheet, and (iii) an initial central tension (iCT) within the glass sheet; and annealing the glass sheet, after the ion exchange process has been completed, by elevating the glass sheet to one or more second temperatures for a second period of time such that at least one of the initial compressive stress (iCS), the initial depth of compressive layer (iDOL), and the initial central tension (iCT) are modified. | 03-27-2014 |
20140239034 | METHODS OF MANUFACTURING A THIN GLASS PANE - Methods of manufacturing a glass pane comprise the steps of providing a glass sheet with a thickness of less than about 1.6 mm between a first major surface and a second major surface of the glass sheet. The methods include scoring the first major surface of the glass sheet to provide a boundary score line and a relief score line. In some examples, the method provides a relief score depth that is greater than a boundary score depth. In another example, the method includes the step of placing the glass sheet on a conveyor belt including a Shore A hardness of greater than or equal to 70. In further examples, methods of breaking a glass sheet with an oversized template are provided. | 08-28-2014 |
20150132538 | GLASS LAMINATE CONSTRUCTION FOR OPTIMIZED BREAKAGE PERFORMANCE - A glass laminate includes at least one chemically-strengthened glass sheets with a thickness not exceeding 2.0 mm and a polymer interlayer between the glass sheets. Flaws are created in the surface of one of the glass sheets in order to weaken the glass laminate upon an impact event on a first side of the laminate, while retaining the strength of the laminate upon impact on the opposing second side of the laminate. The opposing side of the glass sheet with the flaws or a surface of the other glass sheet may be strengthened with an acid etch treatment in order to further strengthen the laminate upon impact on the opposing second side of the laminate. | 05-14-2015 |
20150251377 | GLASS LAMINATE STRUCTURES FOR HEAD-UP DISPLAY SYSTEM - A glass laminate structure comprising a non-strengthened external glass sheet, a strengthened internal glass sheet, and at least one polymer interlayer intermediate the external and internal glass sheets. The internal glass sheet can have a thickness ranging from about 0.3 mm to about 1.5 mm, the external glass sheet can have a thickness ranging from about 1.5 mm to about 3.0 mm, and the polymer interlayer can have a first edge with a first thickness and a second edge opposite the first edge with a second thickness greater than the first thickness. Other embodiments include external and internal strengthened glass sheets as well as an external strengthened glass sheet and an internal non-strengthened glass sheet. | 09-10-2015 |
20150314571 | STRENGTHENED GLASS AND COMPOSITIONS THEREFOR - A glass laminate structure comprising an external glass sheet and an internal glass sheet wherein one or both of the glass sheets comprises SiO | 11-05-2015 |
Tim Cleary, Portland, OR US
Patent application number | Description | Published |
---|---|---|
20130015871 | SYSTEMS, DEVICES, AND METHODS FOR TWO-SIDED TESTING OF ELECTRONIC DEVICES - Systems, devices, and methods for two-sided testing of electronic devices. These systems, devices, and methods may include the use of a test fixture that is configured to electrically connect a back side electrical pad of a device under test with an auxiliary pad that faces in a different direction than the back side electrical pad. Additionally or alternatively, these systems, devices, and methods also may include the use of a probe head that is configured to form an electrical connection with both the auxiliary pad and a front side electrical pad of the device under test. The systems, devices, and methods also may include providing a test signal to the device under test, receiving a resultant signal from the device under test, and/or analyzing the resultant signal. | 01-17-2013 |
Wayne C. Cleary, Glenshaw, PA US
Patent application number | Description | Published |
---|---|---|
20100089952 | CONDIMENT BOTTLE - A bottle formed of a food-grade plastic material, such as clear polyethylene terephthalate, may include a frustoconical neck portion, a shoulder region, a base region, and a sidewall portion have opposed grip-enhancing surfaces, and elastically deformable pressure panels. A cap for the container may include a valve to control product leakage, and may be sized to allow inversion of the bottle. A generally trapezoidal tab of the cap may be moveable between a closed position covering a cap orifice and an open position outside the plane of the cap. | 04-15-2010 |
20110011894 | CONDIMENT BOTTLE - A bottle formed of a food-grade plastic material, such as clear polyethylene terephthalate, may include a frustoconical neck portion, a shoulder region, a base region, and a sidewall portion have opposed grip-enhancing surfaces, and elastically deformable pressure panels. A cap for the container may include a valve to control product leakage, and may be sized to allow inversion of the bottle. A generally trapezoidal tab of the cap may be moveable between a closed position covering a cap orifice and an open position outside the plane of the cap. | 01-20-2011 |
20120132609 | CONDIMENT BOTTLE - A bottle formed of a food-grade plastic material, such as clear polyethylene terephthalate, may include a frustoconical neck portion, a shoulder region, a base region, and a sidewall portion have opposed grip-enhancing surfaces, and elastically deformable pressure panels. A cap for the container may include a valve to control product leakage, and may be sized to allow inversion of the bottle. A generally trapezoidal tab of the cap may be moveable between a closed position covering a cap orifice and an open position outside the plane of the cap. | 05-31-2012 |