Melo
António Augusto Vieira Melo, Lisboa PT
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20130246995 | SYSTEMS, METHODS, AND APPARATUS FOR MODEL-BASED SECURITY CONTROL - An integrated model-driven application development and execution environment enables declaration of a data-role in an application model. The data-role is based on a property of a data entity in the application model. The data-role provides for the enforcement of domain-specific security policies with respect to data elements corresponding to the data entity. | 09-19-2013 |
António Augusto Vieira Melo, Lisboa PT
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20130246995 | SYSTEMS, METHODS, AND APPARATUS FOR MODEL-BASED SECURITY CONTROL - An integrated model-driven application development and execution environment enables declaration of a data-role in an application model. The data-role is based on a property of a data entity in the application model. The data-role provides for the enforcement of domain-specific security policies with respect to data elements corresponding to the data entity. | 09-19-2013 |
C. Melo, Provincia De Buenos Aires AR
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20090187999 | Process for Producing Exogenous Protein in the Milk of Transgenic Mammals and a Process For Purifying Proteins Therefrom - The invention relates to a non-human transgenic mammal that is useful for the production of a protein of interest that may be toxic to the mammal. The mammal is characterized by the fact that it is transgenic for the production in its milk of an inactive form of the protein of interest, preferably recombinant human insulin. It is not possible to produce recombinant human insulin in transgenic mammals since this molecule has a certain degree of biological activity in the mammals and could be toxic to the mammal. Thus, the invention involves cloning a genetic construct comprising a sequence encoding a modified human insulin precursor under the control of a beta casein promoter in an expression vector. It also involves transfecting the expression plasmid into fetal bovine somatic cells, such as fibroblasts, and enucleating bovine oocytes by nuclear transfer to generate transgenic embryos. The invention gives rise to transgenic bovine that will be able to produce a modified human insulin precursor in their mammary glands. Afterwards, the milk of these transgenic mammals can be collected, the modified human insulin precursor can be converted in vitro into recombinant human insulin, and the recombinant human insulin can be purified to homogeneity as a pure biopharmaceutical product. | 07-23-2009 |
Carlos Alberto Melo, Buenos Aires AR
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20090275645 | METHOD TO INDUCE NEOVASCULAR FORMATION AND TISSUE REGENERATION - The present invention relates, e.g., to a method for inducing arteriogenesis, lymphangiogenesis, vasculogenesis, or cardiomyogenesis, and/or for inducing mitosis or proliferation of a smooth muscle cell, a skeletal muscle cell, or a cardiomyocyte, comprising administering to a cell or tissue in need thereof a dose of a polynucleotide that encodes a vascular endothelial growth factor (VEGF), or that encodes a polypeptide comprising an active site of the VEGF. The coding sequence is operably linked to an expression control sequence; and the dose is sufficient to induce arteriogenesis, lymphangiogenesis, vasculogenesis, or cardiomyogenesis, and/or to induce mitosis or proliferation of a smooth muscle cell, a skeletal muscle cell, or a cardiomyocyte. In preferred embodiments of the invention, the method is a method of tissue regeneration, particularly of cardiomyogenesis; and the polynucleotide (or a polypeptide encoded by such a polynucleotide) is administered into the myocardium. | 11-05-2009 |
20140341972 | METHOD TO INDUCE NEOVASCULAR FORMATION AND TISSUE REGENERATION - The present invention relates, e.g., to a method for inducing arteriogenesis, lymphangiogenesis, vasculogenesis, or cardiomyogenesis, and/or for inducing mitosis or proliferation of a smooth muscle cell, a skeletal muscle cell, or a cardiomyocyte, comprising administering to a cell or tissue in need thereof a dose of a polynucleotide that encodes a vascular endothelial growth factor (VEGF), or that encodes a polypeptide comprising an active site of the VEGF. The coding sequence is operably linked to an expression control sequence; and the dose is sufficient to induce arteriogenesis, lymphangiogenesis, vasculogenesis, or cardiomyogenesis, and/or to induce mitosis or proliferation of a smooth muscle cell, a skeletal muscle cell, or a cardiomyocyte. In preferred embodiments of the invention, the method is a method of tissue regeneration, particularly of cardiomyogenesis; and the polynucleotide (or a polypeptide encoded by such a polynucleotde) is administered into the myocardium. | 11-20-2014 |
Carlos Alberto Melo, Prov. De Buenos Aires AR
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20080229438 | Process of making transgenic mammals that produce exogenous proteins in milk and transgenic mammals produced thereby - The invention relates to a method of producing a protein of interest, comprising making a non-human transgenic mammal that produces said protein in its milk, obtaining said milk from the non-human transgenic mammal and purifying said protein of interest from the milk. Transgenic bovine animals were generated, which are able to produce human growth hormone in mammary glands. The method involves cloning of a genetic construct encoding hGH gene and beta casein promoter conveniently in an expression vector. It also includes transfection procedures into fetal bovine somatic cells, generally fibroblasts, and the nuclear transfer into enucleated bovine oocytes, generating thus transgenic embryos. The method also includes other procedures to generate transgenic embryos for the further expansion of the transgenic herd, such as the subcloning of transgenic female bovines, the superovulation of transgenic cows and their insemination with semen from a non-transgenic or a transgenic male bovine, and the superovulation of non-transgenic cows and their insemination with semen from a transgenic male bovine. Afterwards, transgenic embryos give rise to transgenic cattle that produce human growth hormone in huge amounts in their milk, from which the hormone is completely purified and analysed to fulfill all the requirements for the manufacture of a pure biopharmaceutical product. | 09-18-2008 |
20110072526 | PROCESS FOR PRODUCING EXOGENOUS PROTEIN IN THE MILK OF TRANSGENIC MAMMALS AND A PROCESS FOR PURIFYING PROTEINS THEREFROM - The invention relates to a method of producing a protein of interest, comprising making a non-human transgenic mammal that produces said protein in its milk, obtaining said milk from the non-human transgenic mammal and purifying said protein of interest from the milk. Transgenic bovine animals were generated, which are able to produce human growth hormone in mammary glands. The method involves cloning of a genetic construct comprising the hGH gene and beta casein promoter sequences conveniently in an expression vector. It also includes transfection procedures into fetal bovine somatic cells, generally fibroblasts, and the nuclear transfer into enucleated bovine oocytes, generating thus transgenic embryos. The method also includes other procedures to generate transgenic embryos for further expansion of the transgenic herd, such as the subcloning of transgenic female bovines, the superovulation of transgenic cows and their insemination with semen from a non-transgenic or a transgenic male bovine, and the superovulation of non-transgenic cows and their insemination with semen from a transgenic male bovine. Afterwards, transgenic embryos give rise to transgenic cattle that produce human growth hormone in huge amounts in their milk, from which the hormone is completely purified and analysed to fulfill all the requirements for the manufacture of a pure biopharmaceutical product. | 03-24-2011 |
Carlos Alberto Melo, Del Visio AR
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20100210508 | Method for the Massive Culture of Cells Producing Recombinant Human Erythropoietin - The present invention relates, in general, to a method for the massive culture of recombinant mammalian cells for the production of recombinant human erythropoietin (EPO) in culture medium containing insulin. The present invention also refers to a method of producing EPO and to the EPO thus produced. | 08-19-2010 |
Christopher A. Melo, Johnston, RI US
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20150106118 | Cloud-Based Storage and Retrieval of Medical Information Using Near Field Communication Devices - Systems and methods for using near field communication in a cloud computing environment to store and retrieve medical information are provided. | 04-16-2015 |
David M. Melo, Garden City, NY US
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20110272127 | COMPACT PLATE-FIN HEAT EXCHANGER UTILIZING AN INTEGRAL HEAT TRANSFER LAYER - A heat exchanger includes a housing which maintains a first section that has a first inlet and a first outlet, and a second section that has a second inlet and a second outlet. At least one conductive plate extends between the first section and the second section, wherein the conductive plate transfers heat from a fluid flowing in one of the sections to another fluid flowing in the other of the sections. The sections may be positioned side-by-side such that the fluids' flow is coplanar, or co-curvilinear, and non-intersecting. | 11-10-2011 |
Eduardo Melo, Seattle, WA US
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20150278234 | INLINE WEB PREVIEWS WITH DYNAMIC ASPECT RATIOS - A system for providing inline web previews with dynamic aspect ratios. The system includes an automatic information layout engine to dynamically render a preview of web content located at one or more uniform resource locators contained in a message. The web content previews may be tailored to the display configuration of the device showing the web preview. The system may select an appropriate layout for rendering the web content preview based on one or more properties, such as size, resolution, or aspect ratio, of the display each time the web preview is displayed. Web content previews may be dynamically generated or updated as messages are composed, received, or displayed allowing senders and recipients to see the web content preview in a suitable layout. | 10-01-2015 |
Eduardo De Oliveira Melo, Brasilia-Df BR
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20110252489 | METHOD OF IDENTIFYING PROLIFICACY IN MAMMALS - The present invention refers to a method of predicting prolificacy in mammals, by means of analyzing a specific molecular marker for a novel mutation correlated to the increase of the ovulation rate. The correct and simple identification of the presence of the mutation, provided by the use of the method can be highly useful in the genetic improvement of ewes, as well as flock reproduction management. The invention also refers to a novel mutation in the GDF-9 gene which positively alters the ovulation rate and to the use of said genetic sequence for the production of high prolificacy transgenic animals. | 10-13-2011 |
Fébio Rabelo Melo, Rio De Janeirio-Rj BR
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20110263527 | Sulfated Galactans With Antithrombotic Activity, Pharmaceutical Composition, Method for Treating or Prophylaxis of Arterial or Venous Thrombosis, Method of Extraction and Use Thereof - The present invention relates to low molecular weight sulfated galactans, obtained from algae, particularly genus | 10-27-2011 |
Fernando Melo, Edmonton CA
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20150224399 | SYSTEMS AND METHODS FOR MANAGING GAMEPLAY HISTORY - Systems and methods described herein may maintain and modify, for a player, gameplay history data associated with a set of game titles to produce modified gameplay history data. The systems and methods may validate the modified gameplay history data based on game logic data associated with the set of game titles, where the validating may comprise detecting one or more issues relating to the modified gameplay history data that cause the modified gameplay history data to be invalid based on the game logic data. The systems and methods may resolve a set of issues relating to the modified gameplay history data in response to detecting the set of issues. The systems and methods may filter the modified gameplay history data, based on filter data, to produce filtered gameplay history data, and provide the filtered gameplay history data to a client device operating an imported video game. | 08-13-2015 |
Francisco Melo, Santiago CL
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20100273159 | Nested Multiplex Amplification Method for Identification of Multiple Biological Entities - The present invention provides a novel molecular method for the simultaneous identification and semi-quantification of multiple targeted biological entities from amongst a plurality. This invention discloses a method based on a multiplex nested amplification reaction in a single closed tube. The first amplification reaction relies on a set of large oligonucleotides for the amplification of common loci in all the targeted biological entities. The second nested amplification reaction relies on a set of short oligonucleotide primers that amplifies specific nucleotide sequences from all the amplicons previously produced in the first amplification reaction and generates an amplified product pattern capable of identifying each targeted biological entity. This method offers fast and accurate simultaneous identification of many targeted biological entities in any sample. | 10-28-2010 |
20120171681 | OLIGONUCLEOTIDES, METHODS AND KITS FOR DETECTING AND IDENTIFYING VANCOMYCIN-RESISTANT ENTEROCOCCUS - The present invention relates to methods for detecting the presence or absence of vancomycin resistant enterococci (VRE) in a sample using a multiplex polymerase chain reaction (mtx-PCR) assay. Furthermore, the present invention relates to oligonucleotide primers and kits for the detection of VRE. | 07-05-2012 |
Francisco De Assis Dutra Melo, Recife BR
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20160122790 | PROCESS OF SCALE PRODUCTION AND PURIFICATION OF BACTERIAL CELLULOSE OBTAINED BY GLUCOSE POLYMERIZATION FROM SUGARS OF RENEWABLE SOURCES VIA BIOTECHNOLOGY THROUGH THE PROPAGATION OF GLUCONOACETOBACTER HANSENII LMSPE IN REACTORS AND OBTAINMENT OF PURIFIED CELLULOSE FOR APPLICATION IN HEALTH, PHARMACOTECHNICAL AND COSMETIC DERMATOLOGY AREAS - A process of scale production and purification of bacterial cellulose obtained by glucose polymerization from sugars of renewable sources via biotechnology through the propagation of | 05-05-2016 |
Hendrick Melo, Lexington, MA US
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20140329304 | RAPID PEPTIDOGLYCAN-BASED ASSAY FOR DETECTION OF BACTERIAL CONTAMINATION - The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-β-D-glucan in a sample. | 11-06-2014 |
Jacqueline Melo, Vittel FR
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20150335057 | METHOD OF IMPROVING MICROBIOLOGICAL STABILITY IN A STILL WATER-BASED BEVERAGE AND MICROBIOLOGICALLY SHELF-STABLE STILL WATER-BASED BEVERAGES - The present invention relates to a method of improving microbiological stability in a still water-based beverage with respect to undesirable growth of microbiological spoilage such as yeast and/or mould growth during their preparation and/or storage. | 11-26-2015 |
Jason F. Melo, Hastings-On-Hudson, NY US
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20160110412 | Flexible Graph System for Accessing Organization Information - A method and apparatus for accessing a graph database having nodes and relationships describing an organization. An interface in a computer system receives a request from a client to access information about the organization. Further, the interface in the computer system retrieves the information from the graph database having nodes and relationships describing the organization. Still further, the interface in the computer system sends a portion of the information to the client based on how much of the information is displayable by the client. | 04-21-2016 |
20160110473 | Graph Loader for a Flexible Graph System - A method and apparatus for adding information to a graph database. A computer system receives initial records from a legacy database. The computer system converts the initial records from a source format for the legacy database into nodes and relationships for the graph database. The computer system also stores the nodes and the relationships in the graph database. The graph database stores the information about employees in an organization. Further, the computer system receives a group of records after the initial records have been converted into the nodes and the relationships for the graph database. Still further, the computer system changes at least one of a group of nodes or a group of relationships in the graph database based on the group of records. A synchronization between the legacy database and the graph database occurs. | 04-21-2016 |
Jose Melo, Odivelas PT
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20150354891 | Dynamic Suspension Drying (DSD) to Control Ostwald Ripening - The present invention relates to a process for the control of Ostwald Ripening phenomenon occurring in particle suspensions without the need for addition of stabilizing agents, by using high pressure homogenization at mild conditions in a way that no increase or decrease in particle size occurs, thus allowing the stabilization of the suspension during the isolation step in the form of a dried powder. | 12-10-2015 |
Kathleen Lynn Melo, Stratford, CT US
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20140374508 | TOPICAL SPRAY COMPOSITION AND SYSTEM FOR DELIVERING THE SAME - A topical spray composition and a system for containing and applying the composition is described. The composition has liquid emulsifiers that unexpectedly result in a superior product suitable to be applied homogeneously. | 12-25-2014 |
Kelly Ann Melo, Santa Clarita, CA US
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20140299608 | HIGHCHAIR TRAY COVER SYSTEM WITH MAGNETICALLY ATTACHABLE OBJECTS - A highchair system enables removable attachment of objects to a tray of the highchair and protects the highchair from food and liquid spills. A flexible slipcover is removably attachable to the highchair tray so as to extend over at least an upper surface thereof. A permanent magnet or a ferromagnetic material is associated with the slipcover. Objects, such as a dish or a toy, are held in place on the highchair tray by magnetic attraction forces. Tethered utensils may be removably attachable to the dish. | 10-09-2014 |
Luis G. Melo, Saskatoon CA
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20110044947 | METHODS OF TREATING CARDIAC DISORDERS - The invention feature methods and compositions for treating ischemic and reperfusuin related injury such as cardiac disorders. | 02-24-2011 |
Marcelo Claudio De Souza Melo, Sao Paulo BR
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20140089538 | MANAGED ACCESS TO PERIPHERALS OF A SERVICE TERMINAL - Managed access to one or more peripherals of a service terminal is provided. A master controller controls access to the peripheral(s) by applications of the service terminal, wherein only a single application can access the peripheral(s) at a time, by identifying an application of the applications for placing into an on-focus state in order to enable access to the peripheral(s) by the identified application, and placing the identified application into the on-focus state, where access to the peripheral(s) by the identified application is enabled. The remaining applications of the applications execute in an off-focus state in which the master controller simulates, for the remaining applications, connectivity to the peripheral(s), and in which access to the peripheral(s) by the remaining applications is disabled transparent to the remaining applications while the access to the peripheral(s) by the identified application is enabled. | 03-27-2014 |
Marcel Vasconcelos Melo, Niteroi BR
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20090134093 | PROCESS FOR TREATING EFFLUENTS FROM THE OIL INDUSTRY FOR DISCHARGE OR REUTILIZATION - A process is described for treating effluents from oil production units for discharge or reutilization, to remove oil and other soluble toxic contaminants such as sulphides, benzenes, toluenes, xylenes and polyaromatic hydrocarbons, before discharging or reusing this effluent, especially in an offshore environment. This process for effluent treatment includes a step of changing the thermodynamic equilibrium conditions of an oil-in-water emulsion, followed by a step of separating the oil and the water, to be carried out in an offshore oil production unit. | 05-28-2009 |
Maria Do Socorro Cavalcanti De Melo, Recife BR
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20160054372 | REAL TIME, AUTOMATIC DIAGNOSTIC SYSTEM AND METHOD FOR ELECTRIC NETWORKS - A system and method for performing real-time and automatic diagnostics of failures in equipment located in an electrical grid, such as, for example, transmission and generation grids of electric power, using generic rules that consist in correlating events, especially applied in electrical grid with constant topology changes. | 02-25-2016 |
Nicolas Melo, San Francisco, CA US
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20100233960 | SERVICE DISCOVERY FUNCTIONALITY UTILIZING PERSONAL AREA NETWORK PROTOCOLS - Techniques to provide service discovery via personal area network protocols. A personal area network is generally a network that covers only a few feet or meters of physical space. Personal area networks can be wired or wireless. Wired personal area networks include, for example, Universal Serial Bus (USB) and IEEE 1394 (or FireWire) connections. Wireless personal area networks can include, for example, IrDA, Bluetooth, UWB, Z-Wave and ZigBee. Service discovery results in indication of services that are available via the personal area network and not necessarily the physical devices that provide the services. A wireless device may utilize DNS formatted data over a Bluetooth connection to determine services that are available from other Bluetooth devices within range. | 09-16-2010 |
Pedro Fernando Melo, Medellín CO
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20160031458 | SYSTEM FOR DETECTING DEFECTS IN THE ROUNDNESS OF RAILWAY VEHICLE WHEELS - The present invention discloses a device for evaluating the technical condition of the tread of moving railway vehicles, especially for automated inspection of the loss of roundness of each wheel of circulating railway vehicles, in which a point of measurement is used which generates a signal proportional to rail deformation when a wheel arch passes over said point. Then the comparator system compares the measured signal with a wheel pattern without any roundness defects, which is then transmitted over a data network that associates the wheel identification information, with the wheel defect data generated by the comparator system each time the wheel passes over said measurement area. | 02-04-2016 |
Rafael C. Melo, Joinville BR
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20130152967 | DISHWASHER WITH CLOSED LOOP CONDENSER - A dishwasher with a closed loop condenser having a moist air conduit, a dry air conduit having a portion in overlying relationship with a portion of the moist air conduit, wherein the overlying portions of the moist air conduit and the dry air conduit form a heat exchanger, and a controllable gate for selectively introducing, exhausting, or redirecting air relative to the condenser. | 06-20-2013 |
20130152968 | METHOD OF OPERATING A DISHWASHER WITH CLOSED LOOP CONDENSER - A dishwasher with a closed loop condenser having a moist air conduit, a dry air conduit having a portion in overlying relationship with a portion of the moist air conduit, wherein the overlying portions of the moist air conduit and the dry air conduit form a heat exchanger, and a controllable gate for selectively introducing, exhausting, or redirecting air relative to the condenser. | 06-20-2013 |
20130152981 | DISHWASHER WITH CLOSED LOOP CONDENSER - A dishwasher with a closed loop condenser having a moist air conduit, a dry air conduit having a portion in overlying relationship with a portion of the moist air conduit, wherein the overlying portions of the moist air conduit and the dry air conduit form a heat exchanger, and a controllable gate for selectively introducing, exhausting, or redirecting air relative to the condenser. | 06-20-2013 |
20140059880 | DISHWASHER WITH CONTROLLED DRY CYCLE - A method of drying dishes in a dishwasher having a condensation system for extracting liquid from air within a treating chamber of the dishwasher to control the dry cycle of the dishes in the treating chamber. | 03-06-2014 |
Sandra Patricia Melo, Palm Springs, FL US
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20160066837 | Personal Device and Method for Integration of Mind/Body Focus Energy - The present invention provides a device and related method that uses a physical stimulus ( | 03-10-2016 |
Sónia Melo, Porto PT
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20160024503 | miRNA BIOGENESIS IN EXOSOMES FOR DIAGNOSIS AND THERAPY - Methods for diagnosis and treatment of cancers by use of exosomes comprising miRNAs and precursors thereof. For example, in some aspects, a cancer may be diagnosed or evaluated by determining the miRNA content of exosomes in a sample from a subject or by detecting miRNA processing in exosomes. | 01-28-2016 |
William Melo, Tustin, CA US
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20160132849 | SYSTEM AND METHOD FOR AN ON DEMAND MEDIA KIOSK - A method and system for transferring media on demand to a mobile computing device of a consumer is presented. A sensor in a kiosk identifies a consumer by facial recognition algorithms or identification of the mobile computing device of the consumer. An interactive display presents media that is available for download by the consumer based at least in part on the identity of the consumer. The consumer touches their mobile computing device to a short range communications interface on the kiosk which transfers the media to the mobile computing device. The media can be streamed to the kiosk from a remote content server across a network. The kiosk can process the consumer payment for the downloaded media by sending payment transactions to a payment network. | 05-12-2016 |
William Melo, Irvine, CA US
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20150229793 | MULTI-PURPOSE DOCUMENT EQUIPMENT MANAGEMENT SYSTEM AND METHOD OF USE - Provided herein are systems for management and control of document production devices, as well as methods and software for their use. These systems can include a server configured to host a document management service. The server can have a plurality of local user interfaces adapted for electronic and/or optical data communication with one or more remote user interfaces and one or more document production devices. The server can have a plurality of purpose-specific application interfaces which further communicate over a communications network with a plurality of purpose-specific applications. | 08-13-2015 |