Chiti
Fabrizio Chiti, Scandicci IT
Patent application number | Description | Published |
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20080262742 | COMPUTATIONAL METHOD AND APPARATUS FOR PREDICTING POLYPEPTIDE AGGREGATION OR SOLUBILITY - A prediction method for predicting the effect of an amino acid modification on the rate of aggregation (solubility) of a reference polypeptide comprising: calculating the difference in hydrophobicity (ΔHydr) between the reference polypeptide and a modified polypeptide, calculating the difference in β-sheet propensity (ΔΔG | 10-23-2008 |
20100261882 | METHOD AND APPARATUS FOR ASSESSING POLYPEPTIDE AGGREGATION - A method of determining aggregation rate data predicting an aggregation rate of a polypeptide defined by an amino acid sequence, the method comprising determining a hydrophobicity value, a charge value, and at least one shape propensity value for said sequence; identifying one or more aggregation-influencing patterns within said sequence; determining a pattern value for the sequence responsive to said identifying; and determining said aggregation rate data by determining a weighted combination of said hydrophobicity value, said charge value, said at least one shape propensity value, said pattern value and at least one factor extrinsic to said amino acid sequence. | 10-14-2010 |
Giacomo Chiti, Prato IT
Patent application number | Description | Published |
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20090130049 | Self-Sterilizing Products - Self-sterilising products, and in particular novel products comprising phthalocyanine derivatives bound to polymers, a process for the preparation of said products and their use for preparing self-sterilising industrial and medical articles or devices, are described. | 05-21-2009 |
20090131392 | PHTALOCYANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE - Phthalocyanine derivatives are described having photosensitising characteristics and high solubility in water, useful for photodynamic treatment of bacterial infections, in particular infections generated by Gram-negative bacteria. | 05-21-2009 |
20120135972 | PHTHALOCYANINE DERIVATIVE CONSISTING OF A MIXTURE OF 4 ISOMERS - There is described a phthalocyanine derivative of formula (I) consisting of 4 isomers wherein the relative isomer B content is less than or equal to 1% by weight. | 05-31-2012 |
20140163218 | NOVEL PHTHALOCYANINE DERIVATIVES FOR THERAPEUTIC USE - There are described phthalocyanine derivates, the pharmaceutical compositions and the medical devices that contain them, possibly in combination with chelating agents, such as EDTA, useful for treating, by means of photodynamic therapy, diseases characterised by cellular hyperproliferation, microbial infections caused by Gram− bacteria, Gram+ bacteria and fungi, and for treating various types of infected and non-infected ulcers. | 06-12-2014 |
Giacomo Chiti, Montemurlo IT
Patent application number | Description | Published |
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20090131393 | Process for Preparing Chlorides of Phthalocyanine Derivatives Comprising at Least a Quaternary Ammonium Group - A process is described for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group, products useful as photosensitising agents in photodynamic therapy. | 05-21-2009 |
20110112464 | MESO-SUBSTITUTED PORPHYRINS - Meso-substituted porphyrins of general formula (I) | 05-12-2011 |