Patent application number | Description | Published |
20090049785 | SPORT WALL AND SPORT WALL SYSTEM - An anchoring panel for a sport wall system with a front side facing an interior of the sport wall system, a back side, a flange extending from and rigidly fixed to the back side, a top side, a bottom side, and a first and second end wall is provided. Each of the first and second end walls include interlocking elements for interlocking with a first or second end of another panel in the sport wall system, the interlocking elements comprising at least a male knob extending towards the bottom side of the anchoring panel and configured to be insertable into a panel recess of the another panel in the sport wall system. | 02-26-2009 |
20110047923 | SPORT WALL AND SPORT WALL SYSTEM - An anchoring panel for a sport wall system with a front side facing an interior of the sport wall system, a back side, a flange extending from and rigidly fixed to the back side, a top side, a bottom side, and a first and second end wall is provided. Each of the first and second end walls include interlocking elements for interlocking with a first or second end of another panel in the sport wall system, the interlocking elements comprising at least a male knob extending towards the bottom side of the anchoring panel and configured to be insertable into a panel recess of the another panel in the sport wall system. | 03-03-2011 |
20120036698 | SPORTS SAFETY PADDING - An energy absorbing termination post padding for hockey rinks includes a corner shaped foam pad configured to absorb impacts from sports play such as hockey. Energy absorbing foam panels may include a rigid foam alone or in combination with a relatively softer foam or impact layer. | 02-16-2012 |
20120060265 | SPORTS SAFETY PADDING - An energy absorbing termination post padding for hockey rinks includes energy absorbing foam pads configured to absorb impacts from sports play such as hockey. Energy absorbing foam panels may include a rigid foam alone or in combination with a relatively softer foam or impact layer. | 03-15-2012 |
20130284996 | Sport Wall and Sport Wall System - An anchoring panel for a sport wall system with a front side facing an interior of the sport wall system, a back side, a flange extending from and rigidly fixed to the back side, a top side, a bottom side, and a first and second end wall is provided. Each of the first and second end walls include interlocking elements for interlocking with a first or second end of another panel in the sport wall system, the interlocking elements comprising at least a male knob extending towards the bottom side of the anchoring panel and configured to be insertable into a panel recess of the another panel in the sport wall system. | 10-31-2013 |
20140342852 | SPORTS SAFETY PADDING - An energy absorbing termination post padding for hockey rinks includes energy absorbing foam pads configured to absorb impacts from sports play such as hockey. Energy absorbing foam panels may include a rigid foam alone or in combination with a relatively softer foam or impact layer. | 11-20-2014 |
Patent application number | Description | Published |
20090129735 | OPTICAL FIBER HAVING REDUCED DEFECT DENSITY - An optical fiber comprising a multimode glass core having a diameter of at least 250 microns and an index of refraction and a polymer cladding having a thickness and contactingly surrounding a glass portion of the fiber so as to define an interface between the glass portion and the polymer cladding. The polymer cladding can have a first index of refraction that is less than the index of refraction. The fiber can comprise a density of less than 0.25 non-conforming regions having a diameter of 25 microns or greater per millimeter of length along the fiber, where each of the non-conforming regions is a region visible to the human eye under an optical microscope and having at least a portion thereof within a selected distance of the interface. The selected distance can be less than or equal to the thickness of the polymer cladding. The optical microscope can have a total magnification of about 200. The polymer cladding can be applied to at least a part of the optical fiber in at least a class 1000 environment. Methods of using optical fibers, including receiving with an optical fiber optical energy from a source and guiding the optical energy with the optical fiber, wherein the optical energy comprises at least one of 1) pulses each comprising a peak power of at least 10 kW, 2) an average power of at least 50 Watts, or 3) an average power density of at least 2.9 kW/cm | 05-21-2009 |
20100008634 | OPTICAL FIBER ARTICLE FOR HANDLING HIGHER POWER AND METHOD OF FABRICATING OR USING - An optical fiber preform, and method for fabricating, having a first core, a second core spaced from the first core and first and second regions, the first region having an outer perimeter having a first substantially straight length and the second region having an outer perimeter having a second substantially straight length facing the first straight length. One of the regions can comprise the first core and the other comprises the second core. The preform can be drawn with rotation to provide a fiber wherein a first core of the fiber is multimode at a selected wavelength of operation and a second core of the fiber is spaced from and winds around the first core and has a selected longitudinal pitch. The second core of the fiber can couple to a higher order mode of the first core and increase the attenuation thereof relative to the fundamental mode of the first core. | 01-14-2010 |
20130291603 | OPTICAL FIBER ARTICLE FOR HANDLING HIGHER POWER AND METHOD OF FABRICATING OR USING - An optical fiber preform, and method for fabricating, having a first core, a second core spaced from the first core and first and second regions, the first region having an outer perimeter having a first substantially straight length and the second region having an outer perimeter having a second substantially straight length facing the first straight length. One of the regions can comprise the first core and the other comprises the second core. The preform can be drawn with rotation to provide a fiber wherein a first core of the fiber is multimode at a selected wavelength of operation and a second core of the fiber is spaced from and winds around the first core and has a selected longitudinal pitch. The second core of the fiber can couple to a higher order mode of the first core and increase the attenuation thereof relative to the fundamental mode of the first core. | 11-07-2013 |
Patent application number | Description | Published |
20090035856 | CONTINUOUS PERFUSION BIOREACTOR SYSTEM - Systems and methods for containing and manipulating liquids, including vessels and unit operations or components of cell culture, cell containment, bioreactor, and/or pharmaceutical manufacturing systems, are provided. In certain embodiments, such vessels and unit operations are directed to continuous perfusion reactor or bioreactor systems and may include one or more disposable components. For instance, in one aspect, a system includes an apparatus in the form of a bioreactor for harvesting cells which produce one or more products. The apparatus may include a disposable, collapsible bag adapted for containing a liquid, the collapsible bag in fluid communication with a liquid-solids (e.g., cell) separation device. For example, an outlet of the collapsible bag may be connected to an inlet of the separation device, and an outlet of the separation device may be connected to an inlet of the collapsible bag for recycle. Accordingly, after separating the cells from the liquid in the separation device, the cells can be flowed back into the collapsible bag where they can be re-harvested. Meanwhile, product contained in the liquid can be collected in a separate container. The efficiency of product formation in such a system may be enhanced by using mixing systems described herein. | 02-05-2009 |
20130288346 | LINEARLY SCALABLE SINGLE USE BIOREACTOR SYSTEM - Disclosed is a single-use bioreactor bag design providing substantially equivalent maximum shear rate at the impeller tip and average or bulk shear rate over a range of power per unit working volume and rpm needed for bioculture processing. The uniformity in shear profile of the bag design providing a unique advantage when used as a scale-down or scale-up platform. Also disclosed is a linearly scalable, single-use, bioreactor system for use in carrying out a scalable biomanufacturing process, the system comprising two single-use bioreactor bags of different volumes, wherein the ratio H/D of the height of the working volume H to the diameter D of the tank, or of the bag is equal to about 1.5, and the bulk shear in each of the bags is substantially constant. The disclosed small scale system models larger scale systems from both a shear/scalability/performance basis and also from a validation and regulatory basis. In summary, the 10 L bioreactor system disclosed provides for “linear scalability” by using the same or substantially simulating the same vessel geometry, gas sparging system, impeller shape and type, polymer composition of the flexible bag/components, process control system, and shear rates as larger 50-5000 L systems. | 10-31-2013 |
Patent application number | Description | Published |
20110287519 | HIGH YIELD YELLOW FEVER VIRUS STRAIN WITH INCREASED PROPAGATION IN CELLS - The invention provides a an inactive, non-replicating vaccine comprising whole virion, chemically inactivated Yellow Fever virus which is inactivated using a method that ensures preservation of critical, neutralizing epitopes. The Yellow Fever virus has been adapted to propagate in cells to higher yields than the unadapted virus. The invention also provides methods for preventing Yellow Fever viral infection. | 11-24-2011 |
20120028234 | TISSUE AND ORGAN GRAFT BIOREACTOR AND METHOD OF OPERATION - A single-use, single or multiple tissue, organ, and graft bioreactor and environmental control system is designed to replicate the necessary conditions for growth of tissues, organs, or grafts, while addressing problems in scaling up the tissue growth; adaptation to a single-use or disposable format; and operation as a stand-alone unit that provides full environmental control of cell culture conditions. | 02-02-2012 |
20120190068 | DRAIN DOWN AND RE-FEED OF MICROCARRIER BIOREACTOR - Disclosed is a method of increasing product yield per culture in a population of bound product-secreting cells in a bioreactor, the method comprising: semi-harvesting product by removing a volume of the culture medium with a first-secreted product concentration; re-feeding the bound population of product-secreting cells by adding an amount of a fresh culture medium sufficient to increase the volume of the culture medium to approximately the original volume of the culture medium; agitating the culture medium under sufficient conditions and for a sufficient time period to allow the bound population of product-secreting cells to grow and to release a second-secreted product concentration into the culture medium; and harvesting product. | 07-26-2012 |
20120260671 | DISPOSABLE BIOREACTOR CONDENSER BAG AND FILTER HEATER - Disclosed herein is a system and method for condensing moisture in a moist gas stream entering a bioreactor or leaving a bioretractor, forming a dry gas stream for entering or leaving the bioreactor. | 10-18-2012 |
20140106403 | DRAIN DOWN AND RE-FEED OF MICROCARRIER BIOREACTOR - The invention provides a method of increasing product yield per culture in a population of product-secreting cells bound to a scaffold, for example, a microcarrier, at least partially immersed in a culture medium in a bioreactor. The method comprising: semi-harvesting product by removing a volume of the culture medium with a first-secreted product concentration while leaving the scaffold with the bound cells in the bioreactor; re-feeding the cells by adding a fresh culture medium to increase the culture medium in the bioreactor to approximately the original volume; agitating the culture medium to allow the cells to grow and release a second-secreted product concentration; harvesting product by removing the culture medium with the second-secreted product concentration while leaving the scaffold with the bound cells behind. Also disclosed is a method of increasing virus yield per culture in a population of virus-infected cells bound to a microcarrier suspended in a culture medium. | 04-17-2014 |
20140322270 | HIGH YIELD YELLOW FEVER VIRUS STRAIN WITH INCREASED PROPAGATION IN CELLS - The invention provides a an inactive, non-replicating vaccine comprising whole virion, chemically inactivated Yellow Fever virus which is inactivated using a method that ensures preservation of critical, neutralizing epitopes. The Yellow Fever virus has been adapted to propagate in cells to higher yields than the unadapted virus. The invention also provides methods for preventing Yellow Fever viral infection. | 10-30-2014 |
Patent application number | Description | Published |
20090283682 | MULTI-ENERGY X-RAY IMAGING - An imaging method includes obtaining a first image data for a subset of a target region, the subset of the target region having a first metallic object, obtaining a second image data for the target region, and using the first and second image data to determine a composite image. A imaging system includes a first detector configured to provide a first projection data using a first radiation having high energy, and a second detector configured to provide a second projection data using a second radiation having low energy, wherein the first detector has a first length, the second detector has a second length, and the first length is less than 75% of the second length. | 11-19-2009 |
20100051833 | Energy Modulator for Modulating an Energy of a Particle Beam - An energy modulator for use with a particle source that provides a beam of particles includes a first block moveable between a first position and a second position, wherein when the first block is at the second position, it is in a path of the beam, and a second block moveable relative to the first block, wherein the second block and the first block are offset from each other in a direction of the beam, wherein the first block has a first energy absorption characteristic, and the second block has a second energy absorption characteristic that is different from the first energy absorption characteristic. | 03-04-2010 |
20120097871 | ENERGY MODULATOR FOR MODULATING AN ENERGY OF A PARTICLE BEAM - An energy modulator for use with a particle source that provides a beam of particles includes a first block moveable between a first position and a second position, wherein when the first block is at the second position, it is in a path of the beam, and a second block moveable relative to the first block, wherein the second block and the first block are offset from each other in a direction of the beam, wherein the first block has a first energy absorption characteristic, and the second block has a second energy absorption characteristic that is different from the first energy absorption characteristic. | 04-26-2012 |
20130085778 | ELECTRONIC MEDICAL CHART - A handheld electronic device includes a network communication device for wirelessly receiving information regarding a plurality of tasks involved in a treatment process for a patient from a database, a processor for processing the information regarding the plurality of tasks, a housing containing the processor, wherein the housing is configured for handheld, and a screen configured to display a graphic using the information regarding the plurality of tasks, the graphic indicating the plurality of tasks on respective dates in a time line. | 04-04-2013 |
20140110594 | MULTI-ENERGY X-RAY IMAGING - An imaging method includes obtaining a first image data for a subset of a target region, the subset of the target region having a first metallic object, obtaining a second image data for the target region, and using the first and second image data to determine a composite image. A imaging system includes a first detector configured to provide a first projection data using a first radiation having high energy, and a second detector configured to provide a second projection data using a second radiation having low energy, wherein the first detector has a first length, the second detector has a second length, and the first length is less than 75% of the second length. | 04-24-2014 |
Patent application number | Description | Published |
20080273659 | Radiation systems - A radiation system includes a first ring, a radiation source capable of providing radiation suitable for treating a patient, the radiation source secured to the first ring, a second ring located behind the first ring, and an imager secured to the second ring. A radiation system includes a first device having a radiation source capable of generating a radiation beam suitable for treating a patient, and a second device having imaging capability, wherein the first device is oriented at an angle that is less than 180° relative to the second device. A radiation system includes a structure having a first opening, a radiation source rotatably coupled to the structure, an imaging device rotatable relative to the structure, and a processor for controlling a rotation of the radiation source and a rotation of the imaging device, wherein the radiation source is rotatable relative to the imaging device. | 11-06-2008 |
20090202045 | TREATMENT BOOTH FOR RADIATION THERAPY - A radiation system includes a frame having a housing, a radiation source disposed in the housing of the frame, and a supporting device. The frame is curve-shaped and rotatably supported on a floor partially enclosing a space. The supporting device is disposed in the space and movable. The supporting device is adapted to support a patient in a generally seated position. A radiation method is also provided. | 08-13-2009 |
20110313231 | RADIATION SYSTEMS - A radiation system includes a first ring, a radiation source capable of providing radiation suitable for treating a patient, the radiation source secured to the first ring, a second ring located behind the first ring, and an imager secured to the second ring. A radiation system includes a first device having a radiation source capable of generating a radiation beam suitable for treating a patient, and a second device having imaging capability, wherein the first device is oriented at an angle that is less than 180° relative to the second device. A radiation system includes a structure having a first opening, a radiation source rotatably coupled to the structure, an imaging device rotatable relative to the structure, and a processor for controlling a rotation of the radiation source and a rotation of the imaging device, wherein the radiation source is rotatable relative to the imaging device. | 12-22-2011 |