Xu, NJ
Bibo Xu, Belle Mead, NJ US
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20130067796 | Bed Bug Trap or Barrier Surrounding a Bed - A bed bug device to trap or stop bed bugs may include a substantially vertical back wall having a first layer of detachably connected adhesive to detachably attach to a bed, a top wall being connected to the vertical back wall to prevent a user from interfering with the operation of the bed bug device, a bottom wall being connected to the top wall, and a second adhesive being connected to the vertical back wall to trap the bed bugs. This bed bug device or a double sided adhesive tape or a slippery tape (one face is slippery and the other face is adhesive) may be stuck to a special mattress cover to generate an upside down rectangular prism box shaped bed bug device, so that bed bugs hiding anywhere in the bedroom may not be able to travel to the top of the bed. | 03-21-2013 |
Bingxiong Xu, Edison, NJ US
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20080204124 | Fine-Grained Power Management of Synchronous and Asynchronous Datapath Circuits - A power management circuit is provided for controlling power dissipation in at least one combinational logic circuit. The power management circuit includes a detector operative to receive at least a first input signal to the combinational logic circuit and to detect a transition of the first input signal between a first logic state and a second logic state. The detector generates a control signal indicative of whether or not a transition of the first input signal has occurred. The power management circuit further includes a controller operative to receive the first control signal generated by the detector and to selectively disconnect the first combinational logic circuit from a power supply to the first combinational logic circuit when no logic transition of the first input signal is detected between a preceding computational cycle and a present computational cycle of the first combinational logic circuit, and to connect the first combinational logic circuit to the power supply when a logic transition of the first input signal is detected. | 08-28-2008 |
Chenjian Xu, Short Hills, NJ US
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20110173135 | Methods and Systems for Risk Management - In one aspect, the invention comprises acquiring background data regarding securities positions and regarding real-time pricing data; performing calculations regarding intermediate measures of performance of the securities; receiving configuration data for a portfolio of securities and one or more data requests, at least one of the data requests comprising a request for a value at risk report regarding the portfolio; and providing a value at risk report based on a Parkinson's volatility estimation. In another aspect, the invention comprises displaying a tree structure display in a first portion of a graphical user interface display; in response to a user selecting an item from the tree structure display, displaying a corresponding listing in a tabular display in a second portion of the graphical user interface display; and in response to the user selecting a listing in the tabular display, displaying a corresponding item in the tree structure display. | 07-14-2011 |
Daguang Xu, Plainsboro, NJ US
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20160005166 | User-Guided Shape Morphing in Bone Segmentation for Medical Imaging - A semi-automatic approach is used for user-guided bone segmentation in medical imaging. The user indicates a plurality of landmarks on an image of the bone. A processor morphs the same landmarks on a model of the bone to the user input landmarks on the image, resulting in a transform. This transform is then applied to the model to roughly segment the bone. The user may edit the resulting fit, and the processor then refines the edited fit, such as fitting the bone model to the scan data and avoiding any overlap with other bones. This user-guided segmentation may avoid the need for many samples to train a classifier for a fully automated approach while also avoiding the tedious outlining in a manual approach. | 01-07-2016 |
Dahai Xu, Livingston, NJ US
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20100157847 | METHOD AND APPARATUS FOR PROVIDING REDUNDANCY FOR AN ACCESS NETWORK - A method and apparatus for providing redundancy for an access network are disclosed. For example, the method receives an access network structure, and removes one or more unnecessary 2D edges or 3D edges from a simplex cover for the access network structure. The method then performs a search on the simplex cover; and, generates a new access network structure that includes the redundancy. | 06-24-2010 |
20110141877 | Method of simple and efficient failure resilient load balancing - A resilient load balancing method uses fixed paths and a fixed path-splitting strategy to enable ingress routers to efficiently reroute traffic after a failure. An off-line management system computes a set of fixed paths and a set of splitting ratios for routing demand from ingress routers to egress routers, with sufficient capacity to meet demands under each failure scenario. That data is then used by the ingress router to reroute demand after observing a failure. | 06-16-2011 |
20120087665 | METHOD AND APPARATUS FOR PROVIDING A ROUTE RECOMMENDATION - A method and apparatus for providing a route recommendation are disclosed. For example, the method obtains network topology information, wherein the network topology information comprises a plurality of underlying subnetwork types for a network. The method creates a cost model for the network, and receives a request from a user for a connection to be supported by the network. The method provides the route recommendation for supporting the connection by applying the cost model. | 04-12-2012 |
20120213520 | Reachability Matrices Spanning Multiple Domains in an Optical Network - A method of providing routes through heterogeneous subsystems in an optical network is disclosed, which includes generating, using a processing device, a reachability matrix based on subnetwork information; and generating, using the processing device, a topology associated with the optical network using the reachability matrix. The method also includes determining, using the processing device, a shortest path through the optical network using the reachability matrix and a cost model graph; and displaying, using a graphical user interface, subsystems associated with the shortest path, regeneration locations associated with the shortest path, wavelengths associated with the shortest path, the topology, and the shortest path. Corresponding apparatus and computer-readable storage media are also disclosed. | 08-23-2012 |
20130182561 | Method Of Simple And Efficient Failure Resilient Load Balancing - A resilient load balancing method uses fixed paths and a fixed path-splitting strategy to enable ingress routers to efficiently reroute traffic after a failure. An off-line management system computes a set of fixed paths and a set of splitting ratios for routing demand from ingress routers to egress routers, with sufficient capacity to meet demands under each failure scenario. That data is then used by the ingress router to reroute demand after observing a failure. | 07-18-2013 |
20130236176 | Reachability Matrices Spanning Multiple Domains in an Optical Network - A method of providing routes through heterogeneous subsystems in an optical network is disclosed, which includes generating, using a processing device, a reachability matrix based on subnetwork information; and generating, using the processing device, a topology associated with the optical network using the reachability matrix. The method also includes determining, using the processing device, a shortest path through the optical network using the reachability matrix and a cost model graph; and displaying, using a graphical user interface, subsystems associated with the shortest path, regeneration locations associated with the shortest path, wavelengths associated with the shortest path, the topology, and the shortest path. Corresponding apparatus and computer-readable storage media are also disclosed. | 09-12-2013 |
20150195186 | METHOD AND APPARATUS FOR PROVIDING A ROUTE RECOMMENDATION - A method and apparatus for providing a route recommendation are disclosed. For example, the method obtains network topology information, wherein the network topology information comprises a plurality of underlying subnetwork types for a network. The method creates a cost model for the network, and receives a request from a user for a connection to be supported by the network. The method provides the route recommendation for supporting the connection by applying the cost model. | 07-09-2015 |
Daigen Xu, North Caldwell, NJ US
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20140044674 | INTERLEUKIN-10 FUSION PROTEINS AND USES THEREOF - The present invention generally relates to fusion proteins of antibodies and interleukin-10 (IL-10). In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease. | 02-13-2014 |
20150218244 | INTERLEUKIN-10 FUSION PROTEINS AND USES THEREOF - The present invention generally relates to fusion proteins of antibodies and interleukin-10 (IL-10). More particularly, the invention concerns fusion proteins of antibodies and mutant IL-10 that exhibit improved properties for use as therapeutic agents, e.g. in the treatment of inflammatory diseases. In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease. | 08-06-2015 |
David Xu, Whippany, NJ US
Patent application number | Description | Published |
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20080249318 | Process for phenylacetic acid derivatives - A process for the production of a compound of Formula I, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable prodrug ester thereof, | 10-09-2008 |
20090275758 | PROCESS FOR PHENYLACETIC ACID DERIVATIVES - A process for the production of a compound of Formula I, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable prodrug ester thereof, | 11-05-2009 |
Di W. Xu, Edison, NJ US
Patent application number | Description | Published |
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20090177480 | System And Method For Identifying Targeted Consumers Using Partial Social Security Numbers - A system and method are used to identify a targeted consumer. The system includes a partial social security number (SSN) system that identifies a partial SSN issued during a preselected time period and a marketing database system. The marketing database system receives a comparison result from a SSN matching system that identifies at least one individual in a consumer database having a partial SSN that matches the partial SSN identified by the partial SSN system. The marketing database system places identifying information of the at least one individual in a marketing database. In one method, an individual is identified as a targeted consumer based on the individual's age being within a preselected age range and the individual's social security number being issued within a predetermined social security number SSN issue date range. Identifying information of the targeted consumer is stored in a contact database, which a business may use to directly market its goods or services. | 07-09-2009 |
20120185338 | ESTIMATING THE SPEND CAPACITY OF CONSUMER HOUSEHOLDS - The spend capacity of a consumer typically increases as the number of consumers in the household increases, since the consumer can draw on the spending power of other consumers in the household. The size of wallet of the household is thus a better indicator of the consumer's spend capacity than an individual size of wallet. All consumers in a given household can be aggregated based on, for example, their address of record. Duplicate tradelines within each household are removed from consideration in a size of wallet estimate. A spend capacity is then estimated for each tradeline using calculations derived from a consumer behavior model. The spend capacities for all tradelines in the household are combined to determine a household size of wallet. Each consumer in the household is then tagged with the household size of wallet, rather than their individual size of wallet, | 07-19-2012 |
20130179216 | ESTIMATING THE SPEND CAPACITY OF CONSUMER HOUSEHOLDS - The spend capacity of a consumer typically increases as the number of consumers in the household increases, since the consumer can draw on the spending power of other consumers in the household. The size of wallet of the household is thus a better indicator of the consumer's spend capacity than an individual size of wallet. All consumers in a given household can be aggregated based on, for example, their address of record. Duplicate tradelines within each household are removed from consideration in a size of wallet estimate. A spend capacity is then estimated for each tradeline using calculations derived from a consumer behavior model. The spend capacities for all tradelines in the household are combined to determine a household size of wallet. Each consumer in the household is then tagged with the household size of wallet, rather than their individual size of wallet. | 07-11-2013 |
Fengyuan Xu, Franklin Park, NJ US
Patent application number | Description | Published |
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20160125095 | LIGHTWEIGHT TEMPORAL GRAPH MANAGEMENT ENGINE - A method and system are provided. The method includes storing, in a memory, temporal data for a temporal graph. The memory includes a temporal graph storage structure having a set of buckets. The temporal data stored in the buckets includes respective data segments implemented using graph edges. Each of the graph edges has a start time and an end time associated therewith. The method further includes the methods, performed by a processor, of: forming an index that categorizes the graph edges based on the end times of the graph edges; positioning the graph edges within respective ones of the buckets for storage using the index such that the graph edges are positioned in the respective ones of the buckets in a chronological order that is based on the end times; and accessing the temporal graph storage structure using the index responsive to a temporal graph query. | 05-05-2016 |
Guofeng Xu, Plainsboro, NJ US
Patent application number | Description | Published |
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20090087461 | ANTI-BACTERIAL PYROCATECHOLS AND RELATED METHODS - The invention includes a compound or an oral care composition comprising a compound represented by the structure (I): | 04-02-2009 |
20090202456 | NOVEL SALTS AND THEIR USES - The invention relates to novel arginine salts, compositions comprising them, and their uses. | 08-13-2009 |
20090320226 | Oral Care Implement - An oral care implement includes a handle, a head mounted to one end of the handle that includes a first face having plurality of tooth cleaning elements extending therefrom and a second face, a store of dentifrice retained at the head, and a film matrix retained at the head containing at least one rapidly releasable agent. A soft tissue cleaner can be included on the second face. The at least one rapidly releasable agent can be provided to the first and/or second faces during use from the film matrix. In addition, dentifrice can be provided to the first and/or second faces during use from the store of dentifrice. The at least one rapidly releasable agent can include, for example, a flavoring agent, a dentifrice, or a therapeutic agent. The toothbrush can be small in size and lightweight so as to be readily portable for use away from the home. | 12-31-2009 |
20110024629 | ANALYSIS OF SUBSTRATES HAVING AGENTS DEPOSITED THEREON - Improved analytical, diagnostic, monitoring, and other methods (and their associated devices) for evaluating the extent of deposition of an agent onto a substrate are described. Exemplary methods may be used in the in the monitoring of the dental health of patients or in the fast, efficient screening and/or characterization of formulations in terms of their use for depositing oral actives onto tooth surfaces. The methods involve the direct or in situ analysis of substrates, onto which agents are deposited, using Near-IR spectroscopy and/or UV spectroscopy. | 02-03-2011 |
20120020900 | DENSENSITIZING DENTIFRICE EXHIBITING DENTAL TISSUE ANTIBACTERIAL AGENT UPTAKE - An oral composition exhibiting increased uptake by dental tissue of antibacterial compounds contained therein and eliminating or substantially reducing the discomfort and pain associated with dentinal hypersensitivity. The composition includes an orally acceptable vehicle for such composition, an effective therapeutic amount of an antibacterial compound, a mixture of anionic surfactant and amphoteric surfactant, the mixture having 0.1 wt. % to 2.0 wt. % anionic surfactant and 0.8 wt. % to 2.0 wt. % amphoteric surfactant, and a potassium ion releasable compound. | 01-26-2012 |
20120064017 | BORINIC COMPOSITIONS - A stabilized oral care composition comprising a borinic acid derivative, e.g., a borinic ester. | 03-15-2012 |
20120269742 | ENZYME ENHANCED BREATH FRESHENING FILM - An orally consumable film composition for delivering breath freshening agents to the oral cavity which is rapidly dissolvable or dispersible in the oral cavity, the composition being comprised of a homogeneous mixture of a water dispersible film forming polymer and an enzyme. | 10-25-2012 |
20120294812 | ORAL CARE COMPOSITIONS - Disclosed herein are methods of enhancing the solubility and delivery of one or more active ingredients found in magnolia extract, or a synthetic analogue thereof, in an oral composition. | 11-22-2012 |
20120301852 | DENTAL STRIP FOR ADMINISTRATION OF ORAL TREATMENT - Described herein, are dental strips comprising a film backing, and an adhesive layer, the adhesive layer comprising a water-swellable polymer and at least one active agent; and uses thereof. | 11-29-2012 |
20120308489 | ORAL CARE COMPOSITIONS - Disclosed herein are methods of enhancing the solubility and delivery of one or more active ingredients found in magnolia extract, or a synthetic analogue thereof, in an oral composition. | 12-06-2012 |
20130017237 | ANTIPLAQUE ORAL CARE COMPOSITIONS - The invention provides oral compositions including a safe and effective amount of a compound represented by the formula (I): | 01-17-2013 |
20130025081 | ORAL CARE IMPLEMENT - An oral care implement includes a handle, a head mounted to one end of the handle that includes a first face having a plurality of tooth cleaning elements extending therefrom and a second face, a store of dentifrice retained at the head, and a film matrix retained at the head containing at least one rapidly releasable agent. A soft tissue cleaner can be included on the second face. The at least one rapidly releasable agent can be provided to the first and/or second faces during use from the film matrix. In addition, dentifrice can be provided to the first and/or second faces during use from the store of dentifrice. The at least one rapidly releasable agent can include, for example, a flavoring agent, a dentifrice, or a therapeutic agent. The toothbrush can be small in size and lightweight so as to be readily portable for use away from the home. | 01-31-2013 |
20130129643 | ORAL CARE COMPOSITIONS - An oral care composition for treating or preventing calculus comprising an anticalculus agent and an antibacterial agent comprising a biphenol compound obtainable from | 05-23-2013 |
20130164228 | COMPOSITIONS COMPRISING GALLATES AND GALLAMIDES - Described herein are compositions for topical use comprising an antibacterially effective concentration of a gallate or gallamide compound which is a polysubstituted cycloalkyl or heterocycloalkyl wherein the substituents are selected from hydroxy, hydroxymethyl, fluoro, chloro, amino, nitro, or a moiety of formula -X-(CO)-(3,4,5-trihydroxyphenyl), wherein X is selected from O and NH, provided that the substituents comprise at least two moieties of formula -X-(CO)-(3,4,5-trihydroxyphenyl) attached to adjacent carbons in free or in orally or topically acceptable salt form, as well as methods of making and using the same. | 06-27-2013 |
20130224271 | Oral Compositions Containing Microaggregates - The invention relates to a composite and oral care compositions for use in the mouth to retard the accumulation of dental plaque and/or calculus. The composite is a microaggregate comprising polymer coated, surfactant stabilized particles of a substantially insoluble metal, metal salt or metal oxide, for example zinc oxide. Also methods for retarding the accumulation of dental plaque and/or calculus are provided. | 08-29-2013 |
20130249159 | Apparatus for Conducting Oral Care Experiments and Method of Forming and Using the Same - An apparatus for conducting oral care experiments with enamel block substrates ( | 09-26-2013 |
20130272973 | Dentifrice Containing Functional Film Flakes - A dentifrice composition comprising an orally acceptable vehicle having distributed therein a water hydratable film flakes having a matrix comprised of a water soluble hydroxy alkyl cellulose polymer and a starch, and flaying entrained therein a constituent selected from therapeutic cosmetic and decorative materials. | 10-17-2013 |
20130280185 | Compounds and Compositions - Described herein are compounds of Formula (I): or a salt thereof; wherein: R1 and R5 are independently selected from H, OH and alkoxy; R | 10-24-2013 |
20130315844 | Oral Care Compositions - Described herein are compositions comprising an active compound from an extract of magnolia, or a derivative thereof; and a non-surfactant electrolyte in an amount effective to stabilize the composition, and methods of making and using the same. | 11-28-2013 |
20140096333 | ORAL CARE IMPLEMENT - An oral care implement includes a handle, a head mounted to one end of the handle that includes a first face having a plurality of tooth cleaning elements extending therefrom and a second face, a store of dentifrice retained at the head, and a film matrix retained at the head containing at least one rapidly releasable agent. A soft tissue cleaner can be included on the second face. The at least one rapidly releasable agent can be provided to the first and/or second faces during use from the film matrix. In addition, dentifrice can be provided to the first and/or second faces during use from the store of dentifrice. The at least one rapidly releasable agent can include, for example, a flavoring agent, a dentifrice, or a therapeutic agent. The toothbrush can be small in size and lightweight so as to be readily portable for use away from the home. | 04-10-2014 |
20140234232 | Oral and Skin Care Compositions Based on a 3,3-Dialkyl-1,1-Biphenyl-2,2-Diol or a 3,3-Dialkenyl-1,1-Biphenyl-2,2-Diol - Described herein are compositions comprising antibacterially effective amounts of a compound of Formula (I): or a salt thereof in which R | 08-21-2014 |
20140242001 | TOOTH FILM FORMULATIONS - The invention provides novel dental film-forming compositions, comprising i. an acrylate/octylacrylamide copolymer, ii. one or more alkyl cellulose ethers, and iii. a solvent, and optionally further comprising whitening materials and/or active agents, together with method for using the same. | 08-28-2014 |
20140312232 | ANALYSIS OF SUBSTRATES HAVING AGENTS DEPOSITED THEREON - Improved analytical, diagnostic, monitoring, and other methods (and their associated devices) for evaluating the extent of deposition of an agent onto a substrate are described. Exemplary methods may be used in the in the monitoring of the dental health of patients or in the fast, efficient screening and/or characterization of formulations in terms of their use for depositing oral actives onto tooth surfaces. The methods involve the direct or in situ analysis of substrates, onto which agents are deposited, using Near-IR spectroscopy and/or UV spectroscopy. | 10-23-2014 |
20140314688 | ORAL CARE COMPOSITIONS - Oral care compositions comprising isobutyl magnolol and n-butyl magnolol. A method of enhancing the solubility of isobutyl magnolol in an oral care composition comprises admixing n-butyl magnolol with an orally acceptable carrier comprising isobutyl magnolol. The composition may be used to treat diseases or conditions of the oral cavity such as caries, gingivitis, periodontitis, tooth yellowing and halitosis. | 10-23-2014 |
20140314829 | PERACID-GENERATING COMPOSITIONS - Described herein are tooth whitening strips comprising an hydratable adhesive film having a granular bleaching ingredient attached thereto, wherein upon hydration, the granular bleaching ingredient releases hydrogen peroxide which is used by an enzyme catalyst having perhydrolytic activity to enzymatically produce an effective amount of peracid bleaching agent from an acyl donor substrate. Methods of making and use the tooth whitening strips are also provided. | 10-23-2014 |
20140338688 | Tooth Whitening Strip - Described herein are tooth whitening strips comprising a hydratable adhesive film with a first side and a second side, the first side having a granular bleaching ingredient attached thereto in an amount effective to whiten teeth, together with methods of making and using the same. | 11-20-2014 |
20140356299 | ORAL CARE COMPOSITIONS - The invention provides oral care compositions comprising isobutyl magnolol and propylene glycol monolaurate, together with methods of making and using the same. Also described is a method of enhancing the solubility of isobutyl magnolol in an oral care composition comprising effective amount of propylene glycol monolaurate. The composition is for use in the treatment of caries, gingivitis, periodontitis, tooth yellowing and halitosis. | 12-04-2014 |
20150086487 | LIQUID ACTIVATION SYSTEM - Described herein are compositions comprising an unactivated liquid, an immobilized sparingly soluble acid or base, such that during storage the unactivated liquid is not in contact with the immobilized sparingly soluble acid or base, but upon use, the unactivated liquid contacts the immobilized sparingly soluble acid or base, whereby the pH of the liquid is altered, thereby activating the liquid to provide a benefit; together with variant and alternative designs, methods of making and using the compositions, and components thereof. | 03-26-2015 |
20150114436 | LIQUID ACTIVATION SYSTEM - Described herein are systems for removing selected components, e.g., stabilizing agents or preservatives, from a liquid composition just prior to use, using activated charcoal or an affinity matrix filter, together with variant and alternative designs, methods of making and using the product, and components thereof. | 04-30-2015 |
20150118167 | SYSTEM PROVIDING ENZYME-CATALYZED REACTION - Described herein are packages for storing and dispensing multi-part tooth whitening formulations, wherein the contents of the parts are mixed, a peracid and/or dioxirane whitening agent is formed. Particular multi-part tooth whitening formulations using this principle and methods of use thereof are also provided. | 04-30-2015 |
20150265511 | SYSTEM PROVIDING PERHYDROLASE-CATALYZED REACTION - Described herein are packages for storing and dispensing multi-part tooth whitening formulations, comprising a deformable material configured to form two or more sealed chambers, e.g., wherein the first chamber contains a low viscosity liquid solution comprising an enzyme having perhydrolytic activity, and the second chamber contains a peroxide source and a at least one acyl donor substrate. Particular multi-part tooth whitening formulations using this principle and methods of use thereof are also provided. | 09-24-2015 |
20150328096 | ORAL CARE PRODUCTS COMPRISING TETRABASIC ZINC CHLORIDE AND TRIMETHYLGLYCINE - The invention provides oral care compositions comprising a mixture of tetrabasic zinc halide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided. | 11-19-2015 |
20150328111 | ORAL CARE PRODUCTS COMPRISING A TETRABASIC ZINC-AMINO ACID-HALIDE COMPLEX - Described herein are oral care compositions comprising a tetrabasic zinc halide and an amino acid; along with methods of making and using the same. | 11-19-2015 |
20150328112 | ORAL CARE PRODUCTS COMPRISING ZINC OXIDE AND TRIMETHYLGLYCINE - Described herein are oral care compositions comprising a mixture of zinc oxide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided. | 11-19-2015 |
20150328120 | ORAL CARE COMPOSITION COMPRISING AN AMADORI COMPOUND - The present invention relates to oral care compositions and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm. Disclosed herein are oral care compositions comprising an Amadori compound having a glucose moiety and an amino acid moiety. The Amadori compound has use for inhibiting oral microbial biofilm formation and/or degrading an oral microbial biofilm in the oral cavity of a mammalian subject. | 11-19-2015 |
Guofeng Xu, Princeton, NJ US
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20100048706 | Ethoxylated and/or Hydrogenated Oil Adduct - A composition of matter comprising an oil adduct synthesized by an oil and an addition material, wherein the oil includes at least one member chosen from an ethoxylated oil, a hydrogenated oil, and an ethoxylated and hydrogenated oil: wherein the average degree of ethoxylation in the ethoxylated (optionally hydrogenated) oil is less than about 10 based on moles of ethylene oxide per mole of oil: wherein the hydrogenated (optionally ethoxylated) oil has an iodine value of less than about 75: wherein the oil is capable of undergoing reaction with the addition material through a hydroxyl group of tile oil; and wherein the addition material includes at least one member chosen from carboxylic acid anhydrides, maleic anhydride, dicarboxylic acids, fumaric acid, maleic acid, succinic acids alpha hydroxy acids, beta hydroxy acids, lactic acid, glycolic acid, lactobionic acid, carnitine, salicylic acid, and (meth)acrylic acid. | 02-25-2010 |
Hai Xu, Kenvil, NJ US
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20160110757 | SYSTEM AND METHOD FOR DETECTING AND CORRELATING INDIVIDUAL ACTION INFORMATION TO MEDIA CONTENT DISTRIBUTION - Provided is a method for correlating individual action information with media content distribution, the method including obtaining data related to a presence of an external terminal relative to an output device providing media content, obtaining identifying information of a user associated with the detected external terminal, and storing, in a memory, data received from another party which indicates an action of the user at a virtual or physical location associated with a product or service presented in the provided media content. | 04-21-2016 |
Hanping Xu, Edgewater, NJ US
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20110161958 | Method and system for managing business calculations using multi-dimensional data - A method and system for managing and executing business formulas using a single platform includes a storage function for storing a plurality of business formulas in a single repository, where each business formula is defined using multi-dimensional data. The multi-dimensional data is accessible by employee-users of the business through a server communicatively connected to the repository. The employee-user may alter the multi-dimensional data of a business formula to incorporate modifications, as well as to create new business formulas. The server functions to execute business formulas contained within the repository. By allowing employee-users to modify existing business formulas and to input new business formulas directly into the system without requiring a programmer to write new software code, the efficiency of executing business formulas and implementing modifications is increased. | 06-30-2011 |
Hong Xu, Montgomery, NJ US
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20150099851 | CNSL-BASED HYDROCARBON RESINS, PREPARATION AND USES THEREOF - The present invention is directed to resins made from cashew nutshell liquid and vinyl hydrocarbons and processes for manufacturing the resins. These resins exhibit lower viscosity than the phenol-based homologs. They also exhibit good compatibility with a wide range of solvents, mineral and natural oils, epoxy curing agents, liquid epoxy resins, and polymers, which make them suitable additives as non-reactive diluents for solvent-free coating formulations; tackifiers for structural adhesive, pressure sensitive and hot-melt adhesives; stabilizers for lubricants, fuel and polymer formulations; plasticizers for thermoplastic polymers and processing aid for rubber compounding and stabilizers for respective rubber artifacts. These resins are also valuable precursors for the manufacture of epoxy resins and polyols for coating, adhesive and composite formulations exhibiting ameliorated performance in water repellency, anti-corrosion, and fast hardness development during cure. | 04-09-2015 |
20160075805 | CNSL-BASED HYDROCARBON RESINS, PREPARATION AND USES THEREOF - The present invention is directed to resins made from cashew nutshell liquid and vinyl hydrocarbons and processes for manufacturing the resins. These resins exhibit lower viscosity than the phenol-based homologs. They also exhibit good compatibility with a wide range of solvents, mineral and natural oils, epoxy curing agents, liquid epoxy resins, and polymers, which make them suitable additives as non-reactive diluents for solvent-free coating formulations; tackifiers for structural adhesive, pressure sensitive and hot-melt adhesives; stabilizers for lubricants, fuel and polymer formulations; plasticizers for thermoplastic polymers and processing aid for rubber compounding and stabilizers for respective rubber artifacts. These resins are also valuable precursors for the manufacture of epoxy resins and polyols for coating, adhesive and composite omulations exhibiting ameliorated performance in water repellency, anti-corrosion, and fast hardness development during cure. | 03-17-2016 |
Jean Xu, Warren, NJ US
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20080234359 | Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2- methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof - Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-α or the inhibition of PDE4. | 09-25-2008 |
20090048275 | SOLID FORMS COMPRISING 4-[9-(TETRAHYDRO-FURAN-3-YL)-8-(2,4,6-TRIFLUORO-PHENYLAMINO)-9H-PURIN-2-Y- LAMINO]-CYCLOHEXAN-1-OL, COMPOSITIONS THEREOF, AND USES THEREWITH - Solid forms comprising 4-[9-(tetrahydro-furan-3-yl)-8-(2,4,6-trifluoro-phenylamino)-9H-purin-2-ylamino]-cyclohexan-1-ol, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the treatment of various diseases and/or disorders are disclosed. | 02-19-2009 |
20110112307 | SOLID FORMS COMPRISING (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULFONYLETHYL]-4-ACETYLAMINOI- SOINDOLINE-1,3-DIONE, COMPOSITIONS THEREOF, AND USES THEREOF - Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-α or the inhibition of PDE4. | 05-12-2011 |
20120101144 | SOLID FORMS COMPRISING (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULFONYLETHYL]-4-ACETYLAMINOI- SOINDOLINE-1,3-DIONE, COMPOSITIONS THEREOF, AND USES THEREOF - Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-α or the inhibition of PDE4. | 04-26-2012 |
20120115890 | SOLID FORMS COMPRISING 4-[9-(TETRAHYDRO-FURAN-3-YL)-8-(2,4,6-TRIFLUORO-PHENYLAMINO)-9H-PURIN-2-Y- LAMINO]-CYCLOHEXAN-1-OL, COMPOSITIONS THEREOF, AND USES THEREWITH - Solid forms comprising 4-[9-(tetrahydro-furan-3-yl)-8-(2,4,6-trifluoro-phenylamino)-9H-purin-2-ylamino]-cyclohexan-1-ol, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the treatment of various diseases and/or disorders are disclosed. | 05-10-2012 |
20120232100 | SOLID FORMS OF 3-(5-AMINO-2-METHYL-4-OXO-4H-QUINAZOLIN-3-YL)-PIPERIDINE-2,6-DIONE, AND THEIR PHARMACEUTICAL COMPOSITIONS AND USES - Solid forms comprising 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their uses are disclosed | 09-13-2012 |
20140046057 | SALTS AND SOLID FORMS OF (S)-3-(4-((4-(MORPHOLINOMETHYL)BENZYL)OXY)-1-OXOISOINDOLIN-2-YL)PIPERIDIN- E-2,6-DIONE AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME - Salts and solid forms of 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, or a stereoisomer thereof, are disclosed. Compositions comprising and methos of using the salts and solid forms are also disclosed. | 02-13-2014 |
20140100259 | SOLID FORMS COMPRISING (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULFONYLETHYL]-4-ACETYLAMINOI- SOINDOLINE-1,3-DIONE, COMPOSITIONS THEREOF, AND USES THEREOF - Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-α or the inhibition of PDE4. | 04-10-2014 |
20140315908 | PHARMACEUTICAL FORMULATIONS, PROCESSES, SOLID FORMS AND METHODS OF USE RELATING TO 1-ETHYL-7-(2-METHYL-6-(1H-1,2,4-TRIAZOL-3-YL)PYRIDIN-3-YL)-3,4-DIHYDROPYR- AZINO[2,3-b]PYRAZIN-2(1H)-ONE - Provided herein are formulations, processes, solid forms and methods of use relating to 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one. | 10-23-2014 |
20140378484 | SOLID FORMS OF 3-(5-AMINO-2-METHYL-4-OXO-4H-QUINAZOLIN-3-YL)-PIPERIDINE-2,6-DIONE, AND THEIR PHARMACEUTICAL COMPOSITIONS AND USES - Solid forms comprising 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their uses are disclosed | 12-25-2014 |
20150094473 | SOLID FORMS OF 3-(4-NITRO-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE - Solid forms comprising crystalline 3-(4-nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione are disclosed. Compositions comprising the solid forms, methods of making the solid forms and methods of their use are also disclosed. | 04-02-2015 |
20150196535 | SOLID FORMS COMPRISING (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULFONYLETHYL]-4-ACETYLAMINOI- SOINDOLINE-1,3-DIONE, COMPOSITIONS THEREOF, AND USES THEREOF - Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-α or the inhibition of PDE4. | 07-16-2015 |
20150210650 | SOLID FORMS OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRI- MIDINE-5-CARBOXAMIDE, COMPOSITIONS THEREOF AND METHODS OF THEIR USE - Provided herein are formulations, processes, solid forms and methods of use relating to 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide. | 07-30-2015 |
Jean Xu, Skillman, NJ US
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20110014163 | Differentiation of Human Embryonic Stem Cells - The present invention provides a method for lowering blood glucose levels in an animal by transplanting a population of pancreatic endocrine precursor cells into an animal. | 01-20-2011 |
20110014702 | Differentiation of Human Embryonic Stem Cells - The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present invention provides a method to produce cells capable of producing insulin following transplantation into an animal. | 01-20-2011 |
20110014703 | Differentiation of Human Embryonic Stem Cells - The present invention provides methods to promote the differentiation of pluripotent stem cells into cells expressing markers characteristic of the pancreatic endocrine lineage that co-express PDX1, NKX6.1, but do not express CDX2 and NGN3. | 01-20-2011 |
20110151560 | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS - The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present invention provides a method to produce cells expressing markers characteristic of the pancreatic endocrine lineage that co-express NKX6.1 and insulin and minimal amounts of glucagon. | 06-23-2011 |
20110281355 | Differentiation of Human Embryonic Stem Cells - The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present invention provides a method to produce a population of cells expressing markers characteristic of the pancreatic endoderm lineage, wherein greater than 50% of the cells in the population co-express PDX1 and NKX6.1. | 11-17-2011 |
20120039955 | Treatment of Diabetes with Pancreatic Endocrine Precursor Cells - The present invention provides a method for lowering blood glucose levels in an animal by transplanting a population of pancreatic endocrine precursor cells into an animal. | 02-16-2012 |
Jean Xu, Raritan, NJ US
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20150159139 | Differentiation of Human Embryonic Stem Cells - The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides an improved method for the formation of pancreatic endoderm, pancreatic hormone expressing cells and pancreatic hormone secreting cells. The present invention also provides methods to promote the differentiation of pluripotent stem cells without the use of a feeder cell layer. | 06-11-2015 |
20150290249 | Differentiation of Human Embryonic Stem Cells - The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides an improved method for the formation of pancreatic endoderm, pancreatic hormone expressing cells and pancreatic hormone secreting cells. The present invention also provides methods to promote the differentiation of pluripotent stem cells without the use of a feeder cell layer. | 10-15-2015 |
20160032250 | Differentiation of Human Embryonic Stem Cells - The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present invention provides a method to produce cells expressing markers characteristic of the pancreatic endocrine lineage that co-express NKX6.1 and insulin and minimal amounts of glucagon. | 02-04-2016 |
Jean Xu, Hillsborough, NJ US
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20100015100 | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS - The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides an improved method for the formation of pancreatic endoderm, pancreatic hormone expressing cells and pancreatic hormone secreting cells. The present invention also provides methods to promote the differentiation of pluripotent stem cells without the use of a feeder cell layer. | 01-21-2010 |
Jianwu Xu, Princeton, NJ US
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20160086097 | Automatic Discovery of Message Ordering Invariants in Heterogeneous Logs - A method and system are provided. The method includes performing, by a logs-to-time-series converter, a logs-to-time-series conversion by transforming a plurality of heterogeneous logs into a set of time series. Each of the heterogeneous logs includes a time stamp and text portion with one or more fields. The method further includes performing, by a time-series-to-sequential-pattern converter, a time-series-to-sequential-pattern conversion by mining invariant relationships between the set of time series, and discovering sequential message patterns and association rules in the plurality of heterogeneous logs using the invariant relationships. The method also includes executing, by a processor, a set of log management applications, based on the sequential message patterns and the association rules. | 03-24-2016 |
Jiayi Xu, Marlboro, NJ US
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20150336946 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF TREATMENT - Novel pyridine-2-carboxamide derivatives of formula I and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are effective as glucokinase activating agents. Pharmaceutical compositions and methods of treatment are also included. The present invention relates to novel pyridine-2-carboxamide derivatives and salts thereof which are effective as glucokinase activating agents. Moreover, it relates to compositions containing such compounds, and methods of treatment. | 11-26-2015 |
20150336991 | NOVEL GLUCOKINASE ACTIVATOR COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF TREATMENT - Novel pyridine-2-carboxamide derivatives of formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are effective as glucokinase activating agents. Pharmaceutical compositions and methods of treatment are also included. | 11-26-2015 |
Jiayi Xu, Rahway, NJ US
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20150336991 | NOVEL GLUCOKINASE ACTIVATOR COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF TREATMENT - Novel pyridine-2-carboxamide derivatives of formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are effective as glucokinase activating agents. Pharmaceutical compositions and methods of treatment are also included. | 11-26-2015 |
Jiayi Xu, Edison, NJ US
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20150322056 | Factor IXa Inhibitors - The present invention provides a compound of Formula (I) | 11-12-2015 |
Jinyou Xu, Scotch Plains, NJ US
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20090258851 | DIARYL SUBSTITUTED ALKANES - The instant invention provides compounds of Formula II which are 5-lipoxygenase activating protein inhibitors. | 10-15-2009 |
20090258885 | Diphenylmethane Derivatives as Inhibitors of Leukotriene Biosynthesis - The instant invention provides compounds of Formula I which are 5-lipoxygenase activating protein inhibitors. Compounds of Formula I are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. | 10-15-2009 |
20100130504 | BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES - The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. | 05-27-2010 |
20100168076 | DIPHENYL SUBSTITUTED ALKANES - The instant invention provides compounds of Formula I which are 5-lipoxygenase activating protein inhibitors. Compounds of Formula (I) are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents. | 07-01-2010 |
20110190308 | NOVEL CYCLIC AZABENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS - The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. | 08-04-2011 |
20110224195 | HETEROCYCLIC COMPOUNDS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES - The present invention is directed to substituted six-membered heterocyclic compounds of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as obesity and diabetes, particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. | 09-15-2011 |
20120108595 | PLATELET-ACTIVATING FACTOR RECEPTOR ANTAGONISTS - Cyclohexyl sulfonamide compounds which are platelet-activating factor (PAF) receptor antagonists. Said compounds may be useful, for example, for the treatment of atherosclerosis or other PAF-mediated disorders, including inflammatory, cardiovascular, and immune disorders. | 05-03-2012 |
20120149674 | Diaryl Substituted Alkanes - The instant invention provides compounds of Formula II which are 5-lipoxygenase activating protein inhibitors. | 06-14-2012 |
20130217695 | BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES - The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. | 08-22-2013 |
20150359793 | BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES - The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. | 12-17-2015 |
Li-An Xu, Branchburg, NJ US
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20110104664 | BIOMARKERS AND METHODS FOR DETERMINING SENSITIVITY TO MICORTUBULE-STABILIZING AGENTS - Biomarkers that are useful for identifying a mammal that will respond therapeutically or is responding therapeutically to a method of treating cancer that comprises administering a microtubule-stabilizing agent. In one aspect, the cancer is breast cancer, and the microtubule-stabilizing agent is an epothilone or analog or derivative thereof, or ixabepilone. | 05-05-2011 |
20140065164 | IP-10 ANTIBODY DOSAGE ESCALATION REGIMENS - In certain embodiments, the present invention provides a method of treating an IP10-related disease in a subject, comprising: (a) administering to the subject a predetermined dosage of an anti-IPIO antibody; (b) detecting the level of the anti-IPIO antibody in a sample of the subject; and (c) if the level of the anti-IPIO antibody from step (b) is below a threshold exposure level, increasing the dosage of the anti-IPIO antibody in the subject such that the IP-10 related disease in the subject is treated. | 03-06-2014 |
20140127229 | IP-10 ANTIBODY DOSAGE ESCALATION REGIMENS - In certain embodiments, the present invention provides a method of treating an IP-10-related disease in a subject, comprising: (a) administering to the subject a predetermined dosage of an anti-IP-10 antibody; (b) detecting the level of the anti-IP-10 antibody in a sample of the subject; and (c) if the level of the anti-IP-10 antibody from step (b) is below a threshold exposure level, increasing the dosage of the anti-IP-10 antibody in the subject such that the IP-10 related disease in the subject is treated. In certain embodiments, the present invention provides an isolated monoclonal anti-idiotypic antibody, or an antigen binding portion thereof, which binds to the anti-IP-10 antibody MDX-1100. | 05-08-2014 |
Libo Xu, Bridgewater, NJ US
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20110172256 | GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE - Glucagon receptor antagonist compounds are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included. | 07-14-2011 |
20150336991 | NOVEL GLUCOKINASE ACTIVATOR COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF TREATMENT - Novel pyridine-2-carboxamide derivatives of formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are effective as glucokinase activating agents. Pharmaceutical compositions and methods of treatment are also included. | 11-26-2015 |
Libo Xu, Rahway, NJ US
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20150336991 | NOVEL GLUCOKINASE ACTIVATOR COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF TREATMENT - Novel pyridine-2-carboxamide derivatives of formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are effective as glucokinase activating agents. Pharmaceutical compositions and methods of treatment are also included. | 11-26-2015 |
Liqing Xu, Tenafly, NJ US
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20080294387 | MARTINGALE CONTROL OF PRODUCTION FOR OPTIMAL PROFITABILITY OF OIL AND GAS FIELDS - A computer-aided lean management (CALM) controller system recommends actions and manages production in an oil and gas reservoir/field as its properties and conditions change with time. The reservoir/field is characterized and represented as an electronic-field (“e-field”). A plurality of system applications describe dynamic and static e-field properties and conditions. The application workflows are integrated and combined in a feedback loop between actions taken in the field and metrics that score the success or failure of those actions. A controller/optimizer operates on the combination of the application workflows to compute production strategies and actions. The controller/optimizer is configured to generate a best action sequence for production, which is economically “always-in-the-money.” | 11-27-2008 |
Lucy Xu, Woodcliff Lake, NJ US
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20140187577 | BIOMARKERS FOR PREDICTING AND ASSESSING RESPONSIVENESS OF THYROID AND KIDNEY CANCER SUBJECTS TO LENVATINIB COMPOUNDS - Biomarkers are provided that are predictive of a subject's responsiveness to a therapy comprising lenvatinib or a pharmaceutically acceptable salt thereof (e.g., lenvatinib mesylate). The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having cancer (e.g., thyroid cancer, kidney cancer), suspected of having cancer, or at risk of developing cancer. | 07-03-2014 |
Ningning Xu, Lawrenceville, NJ US
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20100041717 | N-((3-BENZYL)-2,2-(BIS-PHENYL)-PROPAN-1-AMINE DERIVATIVES AS CETP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROSIS AND CARDIOVASCULAR DISEASES - Compounds of formula (Ia) and (Ib), wherein A, B, C, R | 02-18-2010 |
Qian Xu, Plainsboro, NJ US
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20100232498 | METHOD AND APPARATUS FOR RATE CONTROL ACCURACY IN VIDEO ENCODING AND DECODING - Methods and apparatus are provided for rate control accuracy in video encoding and decoding. An apparatus includes a video encoder for encoding image data using rate control. The rate control involves estimating a quantization step size and adjusting a rounding offset. The rounding offset is capable of being non-constant during the encoding. | 09-16-2010 |
20100290524 | Method and apparatus for joint quantization parameter adjustment - The present principles provides a method and apparatus for jointly adjusting the rounding offset and the quantization step size on a macroblock level to improve the perceptual quality of the fine details of the encoded image. In one implementation, the content of the pictures is analyzed and the smooth regions are identified. A quantization step size value for the picture is initially defined and a rounding offset is adaptively assigned to each macroblock based on the content characteristics. The quantization step size is then calculated for the a particular macroblock according to another content characteristic of the macroblock such that the encoding of the particular macroblock is performed in response to the calculated quantization step size and the rounding offset value of the first block. | 11-18-2010 |
20110051807 | METHOD AND APPARATUS FOR RATE CONTROL ACCURACY IN VIDEO ENCODING - A method and apparatus are provided for rate control accuracy in video encoding. The apparatus includes a video encoder for encoding image data in a single encoding pass using rate control. The rate control involves defining a quantization step size value and a rounding offset value and refining at least the rounding offset value. The image data is encoded responsive to the quantization step size value and the refined rounding offset value. | 03-03-2011 |
20110286513 | METHODS AND APPARATUS FOR ADAPTIVE MODE VIDEO ENCODING AND DECODING - There are provided methods and apparatus for adaptive mode video encoding and decoding. An apparatus includes an encoder for encoding adapted mode mapping information for a mapping between values of a mode index and modes available to encode at least a portion of a picture in a sequence of pictures. The adapted mode mapping information is adapted based on one or more actual parameters of the sequence. | 11-24-2011 |
20120030219 | METHODS AND APPARATUS FOR FILTER PARAMETER DETERMINATION AND SELECTION RESPONSIVE TO VARRIABLE TRANSFROMS IN SPARSITY BASED DE-ARTIFACT FILTERING - There are provided method and apparatus for filter parameter determination and selection responsive to variable transforms in sparsity-based de-artifact filtering. An apparatus includes an encoder for encoding picture data for at least a portion of a picture. The encoder includes a sparsity-based de-artifact filter for performing sparsity-based de-artifact filtering on the portion. One or more filter parameters for the sparsity-based de-artifact filtering are determined and selected responsive to variable transforms. | 02-02-2012 |
20120106627 | METHODS AND APPARATUS FOR VIDEO ENCODING AND DECODING USING ADAPTIVE GEOMETRIC PARTITIONING - Methods and apparatus are provided for video encoding and decoding using adaptive geometric partitioning. An apparatus includes an encoder for encoding picture data for a region in a picture using adaptive geometric partitioning, wherein a subset of geometric partitions used to code the picture data for the region is determined responsive to at least one of a distance and an angle. The distance is measured from a defined point within the region to a partition boundary. The angle is measured with respect to at least a line extending from the defined point within the region to the partition boundary. | 05-03-2012 |
20130044814 | METHODS AND APPARATUS FOR ADAPTIVE INTERPOLATIVE INTRA BLOCK ENCODING AND DECODING - Methods and apparatus are provided for adaptive interpolative intra block encoding and decoding. An apparatus includes a video encoder for encoding at least an intra block in a picture by dividing the intra block into at least a first partition and a second partition, and generating predictions of pixels in the second partition by adaptively interpolating reconstructed pixels from the first partition. | 02-21-2013 |
20130058413 | METHODS AND APPARATUS FOR UNI-PREDICTION OF SELF-DERIVATION OF MOTION ESTIMATION - Methods and apparatus are provided for uni-prediction of self-derivation of motion estimation. An apparatus includes a video encoder for encoding at least a portion of a picture. The video encoder includes a self derivation motion estimator for performing self derivation motion estimation for the portion. The self derivation motion estimation is used for selectively performing uni-prediction or bi-prediction for the portion based on one or more criterion. | 03-07-2013 |
Qiang Xu, East Windsor, NJ US
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20150071108 | PATENT LATENCY MONITORING IN SOFTWARE-DEFINED NETWORKS - In a software defined network having switches including first and last switches and intermediate switches, wherein a default routing path exists between the first and last switches, a system and method are provided for computing path latency. The method includes inserting a respective monitoring rule(s) in each switch, mandating for each switch, forwarding a received rule matching packet to a next switch, and further mandating for the first switch and the last switch, sending a PacketIn message to a controller. The method includes inserting, in each switch, a respective monitoring probe(s) matching the respective monitoring rule(s) in a same switch to initiate mandates specified by the respective monitoring rule(s) in the same switch responsive to an arrival of the packet thereat. The method includes time-stamping the PacketIn messages to generate PacketIn timestamps, aggregating the PacketIn timestamps, and estimating the path latency from an aggregation of PacketIn timestamps. | 03-12-2015 |
20150281076 | Layer 2 Path Tracing Through Context Encoding in Software Defined Networking - A computer implemented method for network monitoring includes providing network packet event characterization and analysis for network monitoring that includes supporting summarization and characterization of network packet traces collected across multiple processing elements of different types in a virtual network, including a trace slicing to organize individual packet events into path-based trace slices, a trace characterization to extract at least 2 types of feature matrix describing those trace slices, and a trace analysis to cluster, rank and query packet traces based on metrics of the feature matrix. | 10-01-2015 |
20160057018 | OPTIMIZATION FRAMEWORK FOR MULTI-TENANT DATA CENTERS - Systems and methods for decoupled searching and optimization for one or more data centers, including determining a network topology for one or more networks of interconnected computer systems embedded in the one or more data center, searching for routing candidates based on a network topology determined, and updating and applying one or more objective functions to the routing candidates to determine an optimal routing candidate to satisfy embedding goals based on tenant requests, and to embed the optimal routing candidate in the one or more data centers. | 02-25-2016 |
20160057054 | Path Selection in Hybrid Networks - Systems and methods for controlling legacy switch routing in one or more hybrid networks of interconnected computers and switches, including generating a network underlay for the one or more hybrid networks by generating a minimum spanning tree (MST) and a forwarding graph (FWG) over a physical network topology of the one or more hybrid networks, determining an optimal path between hosts on the FWG by optimizing an initial path with a minimum cost mapping, and adjusting the initial path to enforce the optimal path by generating and installing special packets in one or more programmable switches to trigger installation of forwarding rules for one or more legacy switches. | 02-25-2016 |
Ruo Xu, Watchung, NJ US
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20100087425 | Substituted N-Arylsulfonylheterocyclic Amines As Gamma-Secretase Inhibitors - This invention discloses novel gamma secretase inhibitors of the formula: | 04-08-2010 |
20100093695 | Substituted N-Arylsulfonylheterocyclic Amines As Gamma-Secretase Inhibitors - This invention discloses novel gamma secretase inhibitors of the formula: | 04-15-2010 |
20100247514 | GAMMA SECRETASE MODULATORS - In its many embodiments, the present invention provides a novel class of heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions. | 09-30-2010 |
20100255005 | GAMMA SECRETASE MODULATORS - In its many embodiments, the present invention provides a novel class of heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions. | 10-07-2010 |
20110110948 | BENZENESULFONYL-CHROMANE, THIOCHROMANE, TETRAHYDRONAPHTHALENE AND RELATED GAMMA SECRETASE INHIBITORS - Disclosed are novel gamma secretase inhibitors of the formula (I): or a pharmaceutically acceptable salt, solvate, or ester thereof, wherein L | 05-12-2011 |
20110236400 | TETRAHYDROPYRANOCHROMENE GAMMA SECRETASE INHIBITORS - Disclosed are novel gamma secretase inhibitors of the formula. Also disclosed are methods of inhibiting gamma-secretase, methods of treating neurodegenerative diseases, and methods of treating Alzheimer's Disease. Also disclosed are processes for preparing alkenes in one reaction step using a mixture of an aldehyde (or ketone) and an alkyl substituted with two electron withdrawing groups, and reacting the mixture with: (a) a sulfonyl halide (e.g., a sulfonyl chloride) and a basic tertiary amine, or, (b) a sulfonyl anhydride and a basic amine, or (c) an aryl-C(O)-halide and a basic tertiary amine, or (d) an aryl-C(O)—O—C(O)-aryl and a basic tertiary amine, or (e) an heteroaryl-C(O)-halide and a basic tertiary amine, or (f) a heteroaryl-C(O)—O—C(O)-heteroaryl and a basic tertiary amine. | 09-29-2011 |
20110257156 | GAMMA SECRETASE MODULATORS - In its many embodiments, the present invention provides novel heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions. | 10-20-2011 |
20110263529 | GAMMA SECRETASE MODULATORS - In its many embodiments, the present invention provides a novel class of heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions. | 10-27-2011 |
20110306593 | GAMMA SECRETASE MODULATORS - In its many embodiments, the present invention provides a novel class of heterocyclic compounds of the formula: as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more disease associated with the central nervous system using such compounds or pharmaceutical compostions. | 12-15-2011 |
20120264736 | BENZENESULFONYL-CHROMANE, THIOCHROMANE, TETRAHYDRONAPHTHALENE AND RELATED GAMMA SECRETASE INHIBITORS - This invention discloses novel gamma secretase inhibitors of the formula: | 10-18-2012 |
Shiyou Xu, Harrison, NJ US
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20090056094 | Piezoelectric composite nanofibers, nanotubes, nanojunctions and nanotrees - Piezoelectric nanostructures, including nanofibers, nanotubes, nanojunctions and nanotrees, may be made of piezoelectric materials alone, or as composites of piezoelectric materials and electrically-conductive materials. Homogeneous or composite nanofibers and nanotubes may be fabricated by electrospinning. Homogeneous or composite nanotubes, nanojunctions and nanotrees may be fabricated by template-assisted processes in which colloidal suspensions and/or modified sol-gels of the desired materials are deposited sequentially into the pores of a template. The electrospinning or template-assisted fabrication methods may employ a modified sol-gel process for obtaining a perovskite phase in the piezoelectric material at a low annealing temperature. | 03-05-2009 |
20110209820 | Piezoelectric composite nanofibers, nanotubes, nanojunctions and nanotrees - Piezoelectric nanostructures, including nanofibers, nanotubes, nanojunctions and nanotrees, may be made of piezoelectric materials alone, or as composites of piezoelectric materials and electrically-conductive materials. Homogeneous or composite nanofibers and nanotubes may be fabricated by electrospinning. Homogeneous or composite nanotubes, nanojunctions and nanotrees may be fabricated by template-assisted processes in which colloidal suspensions and/or modified sol-gels of the desired materials are deposited sequentially into the pores of a template. The electrospinning or template-assisted fabrication methods may employ a modified sol-gel process for obtaining a perovskite phase in the piezoelectric material at a low annealing temperature. | 09-01-2011 |
20110210650 | Piezoelectric composite nanofibers, nanotubes, nanojunctions and nanotrees - Piezoelectric nanostructures, including nanofibers, nanotubes, nanojunctions and nanotrees, may be made of piezoelectric materials alone, or as composites of piezoelectric materials and electrically-conductive materials. Homogeneous or composite nanofibers and nanotubes may be fabricated by electrospinning. Homogeneous or composite nanotubes, nanojunctions and nanotrees may be fabricated by template-assisted processes in which colloidal suspensions and/or modified sol-gels of the desired materials are deposited sequentially into the pores of a template. The electrospinning or template-assisted fabrication methods may employ a modified sol-gel process for obtaining a perovskite phase in the piezoelectric material at a low annealing temperature. | 09-01-2011 |
Xiaochun Xu, Annandale, NJ US
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20140291202 | PRODUCTION OF LOW CLOUD POINT DISTILLATE FUELS - Methods are provided for dewaxing a distillate fuel boiling range feed to improve one or more cold flow properties of the distillate fuel feed, such as cloud point, with reduced consumption of hydrogen during the dewaxing process. The reduced hydrogen consumption is achieved by using a dewaxing catalyst with a reduced content of hydrogenation metals, such as a content of Pt or Pd of from about 0.03 wt % to about 0.35 wt %. A distillate fuel feed can be dewaxed to achieve a desired cloud point differential using a reduced metals content dewaxing catalyst under the same or similar conditions to those required for a dewaxing catalyst with higher metals content. | 10-02-2014 |
20150122701 | PRODUCTION OF LOW CLOUD POINT DIESEL FUELS AND LOW FREEZE POINT JET FUELS - Methods are provided for dewaxing a distillate fuel boiling range feed to improve one or more cold flow properties of the distillate fuel feed, such as cloud point, where the distillate fuel feed is fractionated to produce both a jet fuel product and an arctic diesel fuel product. The decrease of cloud point is achieved by using a feedstock having a concentration of nitrogen of less than about 50 wppm and a concentration of sulfur of less than about 15 wppm. Further, the dewaxing catalyst may have a reduced content of hydrogenation metals, such as a content of Pt or Pd of from about 0.05 wt % to about 0.35 wt %. A distillate fuel feed can be dewaxed to achieve a desired cloud point differential using a reduced metals content dewaxing catalyst under the same or similar conditions to those required for a dewaxing catalyst with higher metals content. | 05-07-2015 |
Xiaolian Xu, Princeton, NJ US
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20120302562 | 4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE - Compounds that may be used to inhibit Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting bone. | 11-29-2012 |
20140256784 | 4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE - Compounds that may be used to inhibit Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting bone. | 09-11-2014 |
Xiaoqing Xu, Plainsboro, NJ US
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20090156577 | 7-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES - The present invention relates to compounds having a structure according to Formula (I) | 06-18-2009 |
20110003800 | BENZIMIDAZOLE DERIVATIVES USEFUL AS TRPM8 CHANNEL MODULATORS - Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: | 01-06-2011 |
20110003801 | BENZIMIDAZOLE DERIVATIVES USEFUL AS TRPM8 CHANNEL MODULATORS - Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: | 01-06-2011 |
20130245085 | BENZIMIDAZOLE DERIVATIVES USEFUL AS TRPM8 CHANNEL MODULATORS - Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: | 09-19-2013 |
20140128428 | COLD MENTHOL RECEPTOR ANTAGONISTS - Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: | 05-08-2014 |
20150150882 | BENZIMIDAZOLE DERIVATIVES USEFUL TRPM8 CHANNEL MODULATORS - Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: | 06-04-2015 |
Xiaowei Xu, Monmounth Junction, NJ US
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20110200566 | Compositions and Methods for the Treatment of Vitiligo - Compositions and methods for darkening skin and treating vitiligo are provided. | 08-18-2011 |
Xiaowei Xu, Monmouth Junction, NJ US
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20090130065 | Multipotent adult stem cells - Isolated human multipotent adult stem cell and isolated populations of cells that include human multipotent adult stem cells are disclosed. Human hair-follicle derived multipotent adult stem cells and methods of preparing isolated populations of cells that include human multipotent adult stem cells are disclosed. Isolated human hair-follicle derived multipotent adult stem cell that can differentiate in culture into a neuronal cell, a glial cell, a melanocyte cell, a muscle cell, an osteocyte, a chondrocyte, and a lymphocyte. Isolated human hair-follicle derived multipotent adult stem cell that can grow in cell culture in spheres are disclosed. Human pancreas derived multipotent adult stem cells, human liver derived multipotent adult stem cells, human kidney derived multipotent adult stem cells, human heart derived multipotent adult stem cells, human neural derived multipotent adult stem cells and methods of preparing isolated populations of cells that include such human multipotent adult stem cells are disclosed. Method of treating an individual who has diabetes, cardiac muscle damage, muscle damage and disease, neurodegenerative disease or nerve damage or injury, bone loss, damage and/or disease, cartilage loss, damage and/or disease, hair loss and immune disorders, are disclosed. | 05-21-2009 |
Xiaozhong Xu, Princeton, NJ US
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20130101232 | Coding Images Using Intra Prediction Modes - A system and a method for decoding at least a portion of an image includes determining a current prediction mode based on a combination of a prediction mode residue and a function of at least one previous prediction mode and decoding the portion of the image using the current prediction mode. | 04-25-2013 |
Yanhui Xu, Princeton, NJ US
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20090291878 | MODULATORS OF PROTEIN PHOSPHATASE 2A HOLOENYME - Atomic coordinates for human serine/threonine protein phosphotase 2A (PP2A) holoenzyme, as well as methods for using these atomic coordinates to prepare inhibitors of PP2A and inhibitors prepared using such methods are provided herein. A biochemical analysis of the interactions of PP2A holoenzyme is also provided. Compositions including mimetics and small molecules of the invention and, optionally, secondary agents may be used to treat disorders in which PP2A activity plays a contributing role. | 11-26-2009 |
Yanjun Xu, Princeton, NJ US
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20090231439 | Method for Propagating Data Through a Video Stream - A method for propagating an error between video frames of a video stream wherein data in a single macroblock is propagated from a first video frame to a second video frame via inter-frame coding. Once integrated into the second video frame, the macroblock may be utilized as the basis for intra-frame coding within the second video frame. Intra-frame coding within the second video frame allows for any error in the data contained in the macroblock to propagate through the second video frame while minimizing the amount of the second video frame dedicated to propagation the existing error(s). Embodiments of the present invention are directed to the application of stress to a decoder, to cause an error in the decoder, and propagation of the error between video frames of a video stream. | 09-17-2009 |
20100199159 | METHOD AND SYSTEM FOR PERFORMING DATA INTEGRITY VERIFICATION OF A TRANSPORT STREAM - A method, system, and computer-readable medium for facilitating integrity verification of a transport stream is provided. Integrity verification is performed without increasing the bit rate of the transport stream by generating a checksum corresponding to a portion of the transport stream and inserting the checksum into a null packet within the transport stream. Utilizing a null packet to carry the checksum allows the checksum to be transmitted without increasing the bit rate of the transport stream. In addition, by creating a checksum corresponding to a portion of the transport stream, integrity verification may be performed on a streaming data file. | 08-05-2010 |
Yanjun Xu, Plainsboro, NJ US
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20090129452 | Method and Apparatus for Producing a Desired Data Compression Output - A method and apparatus for testing the functionality of a data decoder is provided. The functionality of a decoder is examined through the used of a functional bitstream. The functional bitstream is a bitstream which when decoded by a properly functioning decoder, produces a desired output. Such a bitstream can be created by receiving an input bitstream, compressing the input bitstream, thereby creating a compressed input bitstream. The compressed input bitstream is then decompressing, thereby creating an intermediate bitstream. The intermediate bitstream is then compressed, thereby creating a compressed intermediate bitstream. The compressed intermediate bitstream is then decompressed, thereby creating an output bitstream. Finally, a comparison is performed to determine if the output bitstream is equivalent to a desired bitstream. | 05-21-2009 |
Yi Xu, Princeton, NJ US
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20150092556 | TWO-STAGE PRECODING AND USER GROUPING FOR LARGE SCALE MULTIPLE-INPUT MULTIPLE-OUTPUT (MIMO) SYSTEMS - Methods are provided. A method includes determining respective weighted likelihoods corresponding to a plurality of users in a multiple-input multiple-output communication system. The method further includes forming a plurality of user groups from the plurality of users using an iterative K-means clustering technique applied to the plurality of users. The iterative K-means clustering technique is responsive to the respective weighted likelihoods. | 04-02-2015 |
Yiming Xu, Princeton, NJ US
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20100158992 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS - There is disclosed a method for treating or preventing fungal infections comprising the administration of at least one glucan synthase inhibitor of a formula as described above in the specification or a pharmaceutically acceptable salt thereof; also claimed are methods of preparing pharmaceutical compositions comprising a compound as described above in the specification and a carrier, method of treating or preventing fungal infections comprising administration of combinations of glucan synthase inhibitor of a formula as described above in the specification and other antifungal agents, and method of treating or preventing fungal infections comprising administration of pharmaceutical compositions prepared according to a method described above in the specification, and a method of preparing a kit in a single package of the above described pharmaceutical composition and other antifungal agents. | 06-24-2010 |
Yuanxin Xu, Bridgewater, NJ US
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20150226758 | ASSAYS FOR DETECTING THE PRESENCE OR AMOUNT OF AN ANTI-DRUG ANTIBODY - Methods and kits for detecting antibodies (e.g., anti-drug antibodies). Such methods and kits permit the detection of, for example, anti-drug antibodies in human body fluids, such as blood, plasma and serum. | 08-13-2015 |
Zhiling Xu, West Windsor, NJ US
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20140019079 | METHOD AND APPARATUS FOR ALIGNING THE MEASUREMENTS OF COLOR MEASUREMENT INSTRUMENTS - One embodiment of a method for aligning measurements taken by a plurality of color measurement instruments with measurements taken by an industry standard color measurement instrument includes receiving a first set of spectral data from the plurality of instruments, receiving a second set of spectral data from the industry standard instrument, generating initial profiles for the plurality of instruments (by producing, for each given instrument, a first correction that aligns the spectral data taken by the given instrument with the second set of spectral data), mathematically correcting the first set of spectral data using the initial profiles to produce a third set of spectral data, and generating new profiles for the plurality of instruments (by calculating a mean of the third set of spectral data, and producing, for each given instrument, a second correction that aligns the spectral data taken by the given instrument with the mean. | 01-16-2014 |
20140299787 | METHOD AND APPARATUS FOR ALIGNING MEASURED SPECTRAL RADIANCE FACTORS AMONG DIFFERENT INSTRUMENTS - Aligning measurements of fluorescent spectral radiance factors taken by a first instrument with measurements of fluorescent spectral radiance factors taken by a second instrument, without knowledge of the matrix of bispectral luminescent radiance factor of any sample, includes obtaining a fluorescent spectral radiance factor of a reference sample, measured by the first instrument, obtaining the fluorescent spectral radiance factor of the reference sample, measured by the second instrument, obtaining a fluorescent spectral radiance factor of a test sample, measured by the first instrument, and estimating the fluorescent spectral radiance factor of the test sample that would be measured by the second instrument, based on the fluorescent spectral radiance factor of a reference sample, measured by the first instrument, on the fluorescent spectral radiance factor of the reference sample, measured by the second instrument, and on the fluorescent spectral radiance factor of the test sample, measured by the first instrument. | 10-09-2014 |
Zhiling Xu, Princeton Junction, NJ US
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20130154830 | SYSTEM AND APPARATUS FOR GLOSS CORRECTION IN COLOR MEASUREMENTS - An apparatus and system for providing a solution that enables technicians or other technical professionals obtain both an accurate color value for a sample as well as an accurate gloss value while using a spectrophotometer and an integrated gloss meter device. The present invention allows for accurate color and gloss value analysis of samples using improved compensation values by using a reference sensor to correct the variations in intensity of a light source. | 06-20-2013 |
20130293897 | SYSTEM AND APPARATUS FOR MEASUREMENT OF LIGHT SCATTERING FROM A SAMPLE - An apparatus and method for providing a solution that enables technicians or other technical professionals to obtain accurate gloss, haze and DOI values for a reflecting sample due to the surface conditions of the sample. The apparatus and method allow for the generation of a data model of the surface of a sample using a sensor array designed to detect the divergence of a collimated beam of light reflected off the surface of the sample. The same principle enables technical professionals to obtain accurate haze and clarity values for a transparent or translucent sample that is trans-illuminated by light. | 11-07-2013 |
20140129179 | SYSTEM AND APPARATUS FOR MULTI CHANNEL GLOSS MEASUREMENTS - The present invention is directed to an apparatus and method for determining a set of gloss measurement values of a sample to be measured. The invention includes a plurality of light sources having a light output, the plurality of sources configured to project light in the direction of a single sample having a gloss characteristic to be measured, wherein the planes of incidence of the light sources are arrayed at different azimuthal angles about the perpendicular direction of the sample. Furthermore, the invention includes a plurality gloss-sensitive sensors, each positioned at 180 degrees of azimuthal angle from the plurality of light sources so as to receive light reflected off a sample and output a plurality of measured gloss sample channel values and a processor configured to compare the outputs of the plurality of sample channel values and generate a plurality of angle-indexed gloss measurement values. | 05-08-2014 |
20150260648 | SYSTEM AND METHOD FOR HAZE MEASUREMENT - The present invention is directed to an apparatus and method for measuring the haze value of transmissive samples. The apparatus comprises a first light source selectively configurable to emit a first light beam, a second light source selectively configurable to emit a second light beam, an integrating sphere having an outer surface and an inner surface, the inner surface configured to reflect light incident upon the inner surface, the inner surface further enclosing an interior volume. The integrating sphere is further equipped with an exit port configured to emit light from the interior volume of the integrating sphere. The exit port is positioned such that light from the first light source exits the integrating sphere without obstruction, and light from the second light source is diffused on the interior surface of the integrating sphere prior to exiting the exit port. A light detector is also included and is configured to generate a light-intensity signal when light exiting the integrating sphere has passed through a sample and is incident on the light detector. The apparatus further includes a processor configured to receive the light-intensity signal and generate an output signal to a user indicating the haze value. The present invention is also directed to a method of calculating the haze value of a sample using a stored calibration value, a diffuse transmission value (sample-absent diffuse light-intensity value), a direct transmission value (sample-absent direct light-intensity value), a measured diffuse transmission value (sample-present diffuse light-intensity value) and a measured direct transmission value (sample-present direct light-intensity value). | 09-17-2015 |