Gregory, CA
Arthur Gregory, Culver City, CA US
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20090179899 | METHOD AND APPARATUS FOR EFFICIENT OFFSET CURVE DEFORMATION FROM SKELETAL ANIMATION - A method for use in animation includes establishing an influence primitive, associating the influence primitive with a model having a plurality of model points, and for each of the plurality of model points on the model, determining an offset primitive that passes through the model point. Another method includes deforming the model, and determining a deformed position of each of the plurality of model points by using a separate offset primitive for each model point. A computer readable storage medium stores a computer program adapted to cause a processor based system to execute one or more the above steps. | 07-16-2009 |
Arthur D. Gregory, Sherman Oaks, CA US
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20130088497 | MULTIPOINT OFFSET SAMPLING DEFORMATION - A skin deformation system for use in computer animation is disclosed. The skin deformation system accesses the skeleton structure of a computer generated character, and accesses a user's identification of features of the skeleton structure that may affect a skin deformation. The system also accesses the user's identification of a weighting strategy. Using the identified weighting strategy and identified features of the skeleton structure, the skin deformation system determines the degree to which each feature identified by the user may influence the deformation of a skin of the computer generated character. The skin deformation system may incorporate secondary operations including bulge, slide, scale and twist into the deformation of a skin Information relating to a deformed skin may be stored by the skin deformation system so that the information may be used to produce a visual image for a viewer. | 04-11-2013 |
Arthur D. Gregory, Los Angeles, CA US
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20150187113 | MULTIPOINT OFFSET SAMPLING DEFORMATION TECHNIQUES - Systems and methods for performing MOS skin deformations are provided. In one example process, the in vector of a MOS transform may be manually configured by a user. In another example process, a slide/bulge operation may be configured to depend on two or more MOS transforms. Each of the MOS transforms may be assigned a weight that represents the transform's contribution to the overall slide/bulge. In yet another example process, a bulge operation for a MOS vertex may be performed in a direction orthogonal to the attached MOS curve regardless of the direction of the attachment vector. In yet another example process, a ghost transform may be inserted into a MOS closed curve and used to calculate skin deformations associated with first transform of the MOS closed curve. | 07-02-2015 |
Brent Gregory, Cupertino, CA US
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20090106722 | DESIGN AUTOMATION METHOD AND SYSTEM FOR ASSESSING TIMING BASED ON GAUSSIAN SLACK - An automated design process using a computer system includes identifying a set of timing endpoints in a circuit defined by a machine-readable file. Values of slack in the estimated arrival times for the timing endpoints are assigned. Probability distribution functions, such as Gaussian distributions, are assigned for the respective values of slack, and are combined. The combination of probability distribution functions represents a measure of circuit performance. The measure is computed for alternative implementations of the circuit, and used to identify an alternative more likely to meet timing constraints. | 04-23-2009 |
Chris Gregory, La Crescenta, CA US
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20090007901 | SOLAR COLLECTOR SYSTEM FOR SOLAR THERMAL APPLICATIONS - A solar collector system includes a plurality of frames. Each frame includes at least a pair of spaced apart side members, a plurality of cross members connected to the side members, the cross members pivotally moveable from a shipping configuration to a deployed configuration wherein in the deployed configuration, each cross member is positioned relative to an adjacent cross member with a predetermined angle, and a plurality of stantions extending from the frames. The solar collector system further includes a plurality of heliostats, each heliostat mounted to one of the stantions, and a plurality of ballasts coupled to the frames, each ballast having a lower surface contacting the ground without substantially penetrating the ground to maintain a position of the frames on the ground. | 01-08-2009 |
Christian Gregory, La Crescenta, CA US
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20090133685 | HELIOSTAT ARRAY LAYOUTS FOR MULTI-TOWER CENTRAL RECEIVER SOLAR POWER PLANTS - A solar power plant includes central receiver modules arranged in a regular pattern. Each central receiver module includes a tower, a central receiver mounted on the tower, and a heliostat array bounded by a polygon. The heliostat array includes heliostats with mirrors for reflecting sunlight to the central receiver. The heliostats are grouped in linear rows and each of the rows is parallel to another row. The locations of the heliostats are staggered between adjacent rows. The power plant also includes a power block for aggregating power from the central receivers and power conduits for transferring power from the central receivers to the power block. | 05-28-2009 |
20100206294 | HELIOSTAT FIELD CLEANING SYSTEM - Systems and methods of heliostat reflector cleaning via a vehicle in a heliostat field. | 08-19-2010 |
Christian T. Gregory, La Crescenta, CA US
Patent application number | Description | Published |
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20100147401 | Sprinkler With Pressure Regulation - A sprinkler pressure regulator module has a compact arrangement with a shiftable member having an upper cavity for receiving water flow debris, and a portion of a bypass valve may reciprocate therein. The module includes a stator plate directing water into a drive mechanism, such as a turbine drive mechanism. The shiftable member receives fluid flow from a radially outboard direction and is sealed with a cup portion receiving the shiftable member to define a cup cavity. A module exterior surface is separated from a sprinkler housing to define a vent cavity. A pressure release vent communicates with the cup cavity, a vent channel between the cup portion and the exterior surface, the vent cavity, and the exterior environment. The vent cavity and cup portion provide receptacles for debris deposit. Ribs around an opening of the vent channel with the vent cavity generally prevent debris from entering the vent channel. | 06-17-2010 |
20110285147 | APPARATUSES AND METHODS FOR ENERGY STORAGE - Some embodiments relate to an energy storage and generation system, comprising a cable system having a first end portion located at a first elevation and a second end portion located at a second elevation, a plurality of mass carriers supported by the cable system, one or more motor generators coupled with the cable system and with an energy grid, a control system in communication with at least the one or more motor generators, a first mass pile area configured to store mass medium positioned at the first elevation, and a second mass pile area configured to store mass medium positioned at the second elevation that can be higher than the first elevation. The one or more motor generators can move the cable system in an energy storing state and be moved by the cable in an energy generating state. The system can store energy by transferring mass medium from the first mass pile area to the second mass pile area, and can generate energy by transferring mass medium from the second mass pile area to the first mass pile area. | 11-24-2011 |
20120012678 | Sprinkler With Pressure Regulation - A sprinkler pressure regulator module has a compact arrangement with a shiftable member having an upper cavity for receiving water flow debris, and a portion of a bypass valve may reciprocate therein. The module includes a stator plate directing water into a drive mechanism, such as a turbine drive mechanism. The shiftable member receives fluid flow from a radially outboard direction and is sealed with a cup portion receiving the shiftable member to define a cup cavity. A module exterior surface is separated from a sprinkler housing to define a vent cavity. A pressure release vent communicates with the cup cavity, a vent channel between the cup portion and the exterior surface, the vent cavity, and the exterior environment. The vent cavity and cup portion provide receptacles for debris deposit. Ribs around an opening of the vent channel with the vent cavity generally prevent debris from entering the vent channel. | 01-19-2012 |
Christian Thomas Gregory, La Crescenta, CA US
Patent application number | Description | Published |
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20130220310 | SOLAR THERMAL RECEIVER WITH CONCENTRIC TUBE MODULES - A solar thermal receiver with concentric tube modules is disclosed. The outer two tubes ( | 08-29-2013 |
David C. Gregory, Canoga Park, CA US
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20120198813 | THRUST CHAMBER AND ROCKET ENGINE SYSTEM - An engine system includes a thrust chamber that has a cooling channel. The cooling channel is adapted to provide sustained cracking conditions for a fluid at steady-state operating conditions. A turbine has an input in fluid communication with an output of the cooling channel. A pump is mechanically coupled with the turbine and is in fluid communication with the cooling channel. | 08-09-2012 |
David M. Gregory, San Diego, CA US
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20100311186 | DEVICES AND METHODS FOR PERFORMING RECEPTOR BINDING ASSAYS USING MAGNETIC PARTICLES - The present invention provides methods, devices, and systems for performing receptor binding assays. In particular, magnetically responsive particles configured to form a complex with a labeled conjugate corresponding to one or more analytes of interest can be moved within an assay device to one or more discrete detection regions through the application of one or more magnetic fields. By positioning the detection region such that the direction of this movement is, for at least a portion of the movement, counter to the direction of fluid flow within the device, detection of assay signals can be performed without the need for separate wash steps. Moreover, contamination of the signals resulting from labeled conjugate being carried in the direction of fluid flow substantially reduced. | 12-09-2010 |
George D. Gregory, Los Altos, CA US
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20140180934 | Systems and Methods for Using Non-Textual Information In Analyzing Patent Matters - Aspects of the present invention comprise using non-textual information in analyses of patent matters. In embodiments, patent matter similarity may comprise a combination of two or more metrics: (a) a metric that measures the textual similarity between an input patent portfolio and patent matters; (b) a metric that measures the behavior between portfolio patents and other patent matters at issue (e.g., which patents are asserted in the same proceeding with portfolio patents); (c) a metric that measures the textual similarity between the textual description and patent matters; and (d) a metric that inspects which patent matters are placed at issue by peer companies. In embodiments, patent matter similarity may be determined using textual similarity in combination with non-textual information. | 06-26-2014 |
Haydn Gregory, San Jose, CA US
Patent application number | Description | Published |
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20090115318 | ORGANIC ELECTRONIC DEVICE STRUCTURES AND FABRICATION METHODS - An organic electronic device structure, the structure comprising: a substrate; a base layer supported by said substrate and defining the base of a well for solvent-based deposition of organic electronic material; one or more spacer layers formed over said base layer; a bank layer formed over said spacer layer to define a side of said well; and wherein an edge of said well adjacent said base layer is undercut to define a shelf over said base layer, said shelf defining a recess to receive said organic electronic material. | 05-07-2009 |
20090121618 | Solvents for PEDOT-Solutions for Ink-Jet Printing - A composition for ink jet printing an opto-electrical device, the composition comprising: an electroluminescent or charge transporting organic material; and a high boiling point solvent having a boiling point higher than water. | 05-14-2009 |
Jack Gregory, Santa Rosa, CA US
Patent application number | Description | Published |
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20100257713 | HAND-OPERATED RIVET SETTING TOOL - A hand-operated rivet setting tool, having an upper handle, a lower handle, a housing which is connected to the lower handle at its first end and houses a pump assembly and a flexible reservoir, the pump assembly, connected to a flexible reservoir, the front assembly for setting a rivet, having a nose tube connected to a hydraulic cylinder of the pump assembly, a lever assembly, wherein the lever assembly and at least one of the handles are operationally connected to the pump assembly, wherein the pump assembly is sufficiently designed to advance the hydraulic cylinder with the nose tube to set the rivet when the lever of the lever assembly is in a first position, and wherein the pump assembly is sufficiently designed to open a passage for oil to return into the flexible reservoir and the hydraulic cylinder with the nose tube to retrieve toward the housing when the lever of the lever assembly is in a second position. | 10-14-2010 |
Jack T Gregory, Sonoma, CA US
Patent application number | Description | Published |
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20140230615 | Hydraulic Press Pliers Power Hand Tool - A hand operated hydraulic press pliers tool is provided comprising an upper stationary handle having a fixed serrated upper jaw portion forming the front end of the stationary handle and a tubular portion forming the rear end of the stationary handle. A serrated lower jaw is pivotally attached to the stationary handle and disposed opposing the upper jaw portion. A hydraulic cylinder assembly is centrally disposed within the upper stationary handle and pivotally attached at one end within the tubular portion of the upper stationary handle near the rear of the handle, and the front end of the cylinder assembly pivotally attached to the lower serrated jaw between the lower jaw pivot handle attachment point and the serrated portion of the jaw. A lower tool handle is pivotally attached to the cylinder assembly yoke that is the front end of the pump assembly. A pivotally attached lower tool handle provides a pump lever disposed to engage a concentrically disposed hydraulic pump assembly within the cylinder assembly wherein depressing the top of the hydraulic pump assembly forces fluid into the cylinder assembly expanding the length of the cylinder assembly when the handles are squeezed together by a user. The longitudinal expansion pivots the lower serrated jaw towards the upper serrated jaw gripping a work piece disposed by a user between the jaws. Repeated cycles of squeezing and releasing the handles of the tool effectuate an incremental closure of the jaws onto a work piece with increasing pressure with each squeezing cycle. | 08-21-2014 |
James A. Gregory, San Diego, CA US
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20140219971 | ALGAL PRODUCED MALARIAL TRANSMISSION BLOCKING VACCINES - The present invention relates to the production of malaria transmission blocking vaccines in single-celled green algae, particularly algae of the genus | 08-07-2014 |
James Peter Gregory, Berkeley, CA US
Patent application number | Description | Published |
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20150094150 | OPERATION OF A BROWSER-INCOMPATIBLE APPLICATION WITHIN A BROWSER - Disclosed in some examples are methods, machine readable mediums, and systems for allowing a user to utilize an application that is not normally browser-compatible in a browser. In some examples, this may be accomplished by utilizing a source-to-source compiler to compile the source code of the browser-incompatible application itself into browser-compatible code (such as JavaScript). In other examples, this may be accomplished by utilizing a source-to-source compiler to compile the source code of a virtual machine into browser-compatible code (such as JavaScript). Once the virtual machine is rendered browser-compatible, the virtual machine may execute within the browser, and applications that are natively executable on the execution environment simulated by the virtual machine may then be executed within the virtual machine (and by extension, within the browser). | 04-02-2015 |
Jeff Gregory, Mountain View, CA US
Patent application number | Description | Published |
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20150341167 | SECURING A DIRECTED ACYCLIC GRAPH - A method and apparatus for securing a directed acyclic graph (DAG) is described. In one embodiment, an algorithm for encrypting a DAG is described that enables encryption of a DAG given a start node (an entrypoint), the node key for that node, and a path to traverse in the graph, where keys are stored on the edges of the DAG instead of on nodes of the DAG. Storing the keys on the edges of the DAG instead of on nodes of the DAG enables efficient querying of the DAG and the ability for a node to have multiple parents that may change without affecting the node's relationship with the non-changing parents. A unique and cryptographically random key is generated for each node created within the DAG (sometimes referred herein as a unique node key). The node key encrypts the node it is generated for and also any edges exiting the node. The node key is not stored with the node. Instead, the node key is stored on the incoming edge to the node (the edge from its parent node) encrypted with the node key of the parent node. In the case of the root node, there is an implicit edge from outside the DAG where the node key of the root node is stored. | 11-26-2015 |
Joshua Alexander Gregory, Belmont, CA US
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20130340316 | FLOAT LINE HAVING A CLUTCHED BRAKING CAPABILITY - Integrated float line assemblies having braking capability and methods for forming same are disclosed. The integrated float line assembly includes a braided portion slidably captured between the two ends of a float line, wherein the float line can slide along an interior hollow of the braided portion and be selectively braked by engaging the braided portion. The braided portion is provided with substantially rigid end ferrules. Obstruction having a transverse dimension larger than an inner diameter of the ferrule is provided with at least one end of the float line to prevent the braided portion from being separated from the float line. | 12-26-2013 |
Kyle Gregory, Fremont, CA US
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20150205419 | DYNAMIC TACTILE INTERFACE - One variation of a dynamic tactile interface includes a tactile layer defining a peripheral region and a deformable region adjacent the peripheral region; a substrate coupled to the peripheral region, a fluid conduit adjacent the deformable region, a fluid channel fluidly coupled to the fluid conduit, and a via fluidly coupled to the fluid channel and passing through the back surface; a bladder fluidly coupled to the via and the substrate; a structure adjacent a first side of the bladder; and a platen adjacent a second side of the bladder opposite the first side and compressing the bladder against the structure substantially perpendicular the longitudinal axis of the bladder and substantially parallel the substrate to displace fluid from the bladder and into the fluid channel to transition the deformable region from a retracted setting into an expanded setting. | 07-23-2015 |
20150205420 | DYNAMIC TACTILE INTERFACE - The dynamic tactile interface includes: a tactile layer defining a peripheral region and a deformable region adjacent the peripheral region and operable between a retracted setting and an expanded setting; a substrate including an attachment surface and coupled to the peripheral region and defining a fluid conduit adjacent the deformable region and a fluid channel fluidly coupled to the fluid conduit; a border region proximal a periphery of the substrate and defining a cavity configured to receive an instrument, the cavity supporting the instrument in a first configuration and releasing the instrument in a second configuration; and a bladder fluidly coupled to the fluid channel and coupled to the cavity, the instrument compressing a portion of the bladder in the first configuration to displace fluid from the bladder into the fluid channel to transition the deformable region from the retracted setting to the expanded setting. | 07-23-2015 |
Nicole Gregory, San Francisco, CA US
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20100058168 | MULTIPLE VIEWS FOR WEB APPLICATIONS ACROSS MULTIPLE ENDPOINTS - In one example embodiment, a selection may be received from a user of one of a plurality of web applications. Information related to one or more views of the selected application may be assembled and transmitted to a user computing platform for display in a plurality of application areas for a respective plurality of web pages associated with the user. | 03-04-2010 |
Noel T. Gregory, Santa Barbara, CA US
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20090126775 | SOLAR ARRAYS - A solar array including a solar array assembly, hub assembly, and wing assembly. | 05-21-2009 |
Paul E. Gregory, Palo Alto, CA US
Patent application number | Description | Published |
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20110121404 | ADVANCED TRANSISTORS WITH PUNCH THROUGH SUPPRESSION - An advanced transistor with punch through suppression includes a gate with length Lg, a well doped to have a first concentration of a dopant, and a screening region positioned under the gate and having a second concentration of dopant. The second concentration of dopant may be greater than 5×10 | 05-26-2011 |
20120223389 | SEMICONDUCTOR STRUCTURE WITH IMPROVED CHANNEL STACK AND METHOD FOR FABRICATION THEREOF - A method for fabricating a semiconductor structure with a channel stack includes forming a screening layer under a gate of a PMOS transistor element and a NMOS transistor element, forming a threshold voltage control layer on the screening layer, and forming an epitaxial channel layer on the threshold control layer. At least a portion of the epitaxial channel layers for the PMOS transistor element and the NMOS transistor element are formed as a common blanket layer. The screening layer for the PMOS transistor element may include antimony as a dopant material that may be inserted into the structure prior to or after formation of the epitaxial channel layer. | 09-06-2012 |
20130181298 | ADVANCED TRANSISTORS WITH PUNCH THROUGH SUPPRESSION - An advanced transistor with punch through suppression includes a gate with length Lg, a well doped to have a first concentration of a dopant, and a screening region positioned under the gate and having a second concentration of dopant. The second concentration of dopant may be greater than 5×10 | 07-18-2013 |
20130313652 | SEMICONDUCTOR STRUCTURE WITH IMPROVED CHANNEL STACK AND METHOD FOR FABRICATION THEREOF - A method for fabricating a semiconductor structure with a channel stack includes forming a screening layer under a gate of a PMOS transistor element and a NMOS transistor element, forming a threshold voltage control layer on the screening layer, and forming an epitaxial channel layer on the threshold control layer. At least a portion of the epitaxial channel layers for the PMOS transistor element and the NMOS transistor element are formed as a common blanket layer. The screening layer for the PMOS transistor element may include antimony as a dopant material that may be inserted into the structure prior to or after formation of the epitaxial channel layer. | 11-28-2013 |
20140001571 | SEMICONDUCTOR STRUCTURE WITH MULTIPLE TRANSISTORS HAVING VARIOUS THRESHOLD VOLTAGES AND METHOD OF FABRICATION THEREOF | 01-02-2014 |
20140084385 | DEEPLY DEPLETED MOS TRANSISTORS HAVING A SCREENING LAYER AND METHODS THEREOF - A semiconductor transistor structure fabricated on a silicon substrate effective to set a threshold voltage, control short channel effects, and control against excessive junction leakage may include a transistor gate having a source and drain structure. A highly doped screening region lies is embedded a vertical distance down from the surface of the substrate. The highly doped screening region is separated from the surface of the substrate by way of a substantially undoped channel layer which may be epitaxially formed. The source/drain structure may include a source/drain extension region which may be raised above the surface of the substrate. The screening region is preferably positioned to be located at or just below the interface between the source/drain region and source/drain extension portion. The transistor gate may be formed below a surface level of the silicon substrate and either above or below the heavily doped portion of the source/drain structure. | 03-27-2014 |
20140167156 | ADVANCED TRANSISTORS WITH PUNCH THROUGH SUPPRESSION - An advanced transistor with punch through suppression includes a gate with length Lg, a well doped to have a first concentration of a dopant, and a screening region positioned under the gate and having a second concentration of dopant. The second concentration of dopant may be greater than 5×10 | 06-19-2014 |
20140248753 | ANALOG TRANSISTOR - An analog transistor useful for low noise applications or for electrical circuits benefiting from tight control of threshold voltages and electrical characteristics is described. The analog transistor includes a substantially undoped channel positioned under a gate dielectric between a source and a drain with the undoped channel not being subjected to contaminating threshold voltage implants or halo implants. The channel is supported on a screen layer doped to have an average dopant density at least five times as great as the average dopant density of the substantially undoped channel which, in turn, is supported by a doped well having an average dopant density at least twice the average dopant density of the substantially undoped | 09-04-2014 |
Philip D. Gregory, Richmond, CA US
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20130244332 | TAREGTED INTEGRATION AND EXPRESSION OF EXOGENOUS NUCLEIC ACID SEQUENCES - Disclosed herein are methods and compositions for targeted integration of a exogenous sequence into a predetermined target site in a genome for use, for example, in protein expression and gene inactivation. | 09-19-2013 |
20140030240 | METHODS AND COMPOSITIONS FOR MODULATING PD1 - Disclosed herein are methods and compositions for modulating expression of a PD1 gene. | 01-30-2014 |
20140080216 | METHODS AND COMPOSITIONS FOR TREATMENT OF A GENETIC CONDITION - Methods and compositions for a genetic disease are provided. | 03-20-2014 |
20140093913 | METHODS AND COMPOSITIONS FOR TREATMENT OF A GENETIC CONDITION - Methods and compositions for a genetic disease are provided. | 04-03-2014 |
20140120622 | T CELL MODIFYING COMPOUNDS AND USES THEREOF - Methods and compositions for modifying T-cells in which PD1 and/or CTLA-4 is repressed and/or inactivated using fusion proteins such as artificial transcription factors and nucleases. | 05-01-2014 |
20140134723 | NOVEL DNA-BINDING PROTEINS AND USES THEREOF - Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences. | 05-15-2014 |
20140134740 | NOVEL DNA-BINDING PROTEINS AND USES THEREOF - Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences. | 05-15-2014 |
20140134741 | NOVEL DNA-BINDING PROTEINS AND USES THEREOF - Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences. | 05-15-2014 |
20140155468 | METHODS AND COMPOSITIONS FOR REGULATION OF METABOLIC DISORDERS - Cells and methods of using these cells for expressing a transgene expressing a protein that is aberrantly expressed in a metabolic disorders from a safe harbor locus. | 06-05-2014 |
20140301990 | TARGETED DISRUPTION OF T CELL RECEPTOR GENES USING ENGINEERED ZINC FINGER PROTEIN NUCLEASES - Disclosed herein are methods and compositions for modifying TCR genes, using nucleases (zinc finger nucleases or TAL nucleases) to modify TCR genes. | 10-09-2014 |
20140349394 | TARGETED INTEGRATION INTO THE PPP1R12C LOCUS - Disclosed herein are methods and compositions for targeted integration of an exogenous sequence into the human PPP1R12C locus, for example, for expression of a polypeptide of interest. | 11-27-2014 |
20150037304 | METHODS AND COMPOSITIONS FOR MODIFICATION OF HLA - Disclosed herein are methods and compositions for modulating the expression of a HLA locus, including cells that lack expression of one or more classic HLA genes but are not targeted by Natural Killer (NK) cells for lysis. | 02-05-2015 |
20150174169 | DELIVERY METHODS AND COMPOSITIONS FOR NUCLEASE-MEDIATED GENOME ENGINEERING IN HEMATOPOIETIC STEM CELLS - The present disclosure is in the field of genome engineering, particularly targeted modification of the genome of a hematopoietic cell. | 06-25-2015 |
20150225727 | LINEAR DONOR CONSTRUCTS FOR TARGETED INTEGRATION - Disclosed herein are linear donor molecules comprising homology arms of 50-750 base pairs (e.g., 50-100 base pairs) flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell. | 08-13-2015 |
20150252094 | METHODS AND COMPOSITIONS FOR MODIFICATION OF A HLA LOCUS - Disclosed herein are methods and compositions for modulating the expression of a HLA locus or for selectively deleting or manipulating a HLA locus or HLA regulator. | 09-10-2015 |
20150267205 | METHODS AND COMPOSITIONS FOR REGULATION OF ZINC FINGER PROTEIN EXPRESSION - The present disclosure is in the field of genome engineering, particularly regulating targeted modification of the genome. | 09-24-2015 |
20150267223 | METHODS AND COMPOSITIONS FOR REGULATING HIV INFECTION - Methods and compositions for regulating HIV infection and/or replication in which an anti-HIV transgene is integrated into the genome of a cell using a nuclease. | 09-24-2015 |
20150329875 | METHODS AND COMPOSITIONS FOR PREVENTION OR TREATMENT OF A DISEASE - Methods and compositions for treatment of a genetic disease are provided. | 11-19-2015 |
Richard J. Gregory, Carlsbad, CA US
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20080299083 | Adenoviral vectors having a protein IX deletion - This invention provides a recombinant adenovirus expression vector characterized by the partial or total deletion of the adenoviral protein IX DNA and having a gene encoding a foreign protein or a functional fragment or mutant thereof. Transformed host cells and a method of producing recombinant proteins and gene therapy also are included within the scope of this invention. | 12-04-2008 |
Robert Gregory, Calabasas, CA US
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20130031232 | System and Method For Sharing Electronic Information - In one embodiment, the present invention provides a system for interfacing at least one requestor to at least one performer, wherein the at least one requestor is able to transfer electronic data, or portions thereof, ubiquitously with at least one performer, regardless of the format that the at least one requestor and the at least one performer manage their respective electronic information. In particular, the present invention provides a system, wherein the at least one requestor and the at least one performer update electronic, and/ or modify electronic information, or portions thereof, dynamically, in response to requests and responses from at the at least one requestor and the at least one performer. At any given time, any requestor may become a performer and vice versa. | 01-31-2013 |
Sherman A. Gregory, San Diego, CA US
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20100008453 | ANTENNA ARRAY PATTERN DISTORTION MITIGATION - At least one feature provides a way to perform point-to-multipoint transmissions using adaptive or directional antennas while reducing antenna pattern distortion. Generally, rather than transmitting the same waveform to two or more receivers, an information-bearing signal is transformed into different decorrelated waveforms and each decorrelated waveform is transmitted to a different receiver. In one implementation, an information-bearing signal is transformed into two decorrelated signals such that their crosscorrelation, or autocorrelation of the information-bearing signal, is zero or very small. Such decorrelation may be achieved by sending a first signal to a first receiver while sending a second signal, having a radio frequency spectrum that is the spectrally inverted version of the first signal, to a second receiver. In another implementation, a first signal is transmitted to a first receiver and is also transmitted to a second receiver with a time delay. | 01-14-2010 |
20100064536 | MULTI-PANEL ELECTRONIC DEVICE - A multi-panel electronic device and method are disclosed. In a particular embodiment, a method includes receiving first acceleration data from a first sensor coupled to a first portion of an electronic device. The method further includes receiving second acceleration data from a second sensor coupled to a second portion of the electronic device, where a position of the first portion is movable with respect to a position of the second portion. The method further includes determining a configuration of the electronic device at least partially based on the first acceleration data and the second acceleration data. | 03-18-2010 |
20130115967 | ADAPTIVE FLEXIBLE BANDWIDTH WIRELESS SYSTEMS - Methods, systems, and devices are described for providing flexible bandwidth waveforms and channels for wireless communication. Embodiments may utilize portions of spectrum that may not be large enough to fit a standard or normal waveform. Chip rates may be adapted dynamically to generate and/or to receive flexible bandwidth waveforms to fit these portions of spectrum. Scaling factors and/or center frequencies may also be utilized to generate flexible waveforms. A mobile device may receive adjustment information from a base station so that the mobile device may dynamically adjust its chip rate to utilize a flexible bandwidth channel. A base station may simultaneously transmit on a normal bandwidth channel and a flexible bandwidth channel in some cases. Some flexible bandwidth waveforms may be utilized that are larger, or take more bandwidth, than a normal waveform. Flexible bandwidth may also be utilized to split and/or combine frequency channels. | 05-09-2013 |
Susan Gregory, San Diego, CA US
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20090029931 | Topical administrations of antisense compounds to vla-4 for the treatment of respiratory conditions - A method for the treatment and/or prophylaxis of an animal having a respiratory disease or condition associated with airway hyperresponsiveness, eosinophilia, neutrophilia, leukocytes or overproduction of mucus and/or with the expression of integrin α4 comprising administering to the animal a composition comprising from. 0.001 to 1000 μg per kg body weight of the animal of an antisense compound targeted to a nucleic acid molecule encoding integrin α4. | 01-29-2009 |
20090281169 | Compositions and Their Uses Directed to IL-4R Alpha - Disclosed herein are compounds, compositions and methods for modulating the expression of IL-4R alpha in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders related to expression of IL 4R-α, airway hyperresponsiveness, and/or pulmonary inflammation. | 11-12-2009 |
20090312398 | COMPOSITIONS AND THEIR USES DIRECTED TO IL-4R ALPHA - Disclosed herein are compounds, compositions and methods for modulating the expression of IL-4R alpha in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders related to expression of IL 4R-α, airway hyperresponsiveness, and/or pulmonary inflammation. | 12-17-2009 |
20100056606 | Combination therapy using budesonide and antisense oligonucleotide targeted to IL4-receptor alpha - Provided herein is a method for reducing the amount of steroid required for the prevention, amelioration and/or treatment of pulmonary inflammation and/or airway hyperresponsiveness, comprising administration of the steroid and an oligonucleotide targeted to IL-4R alpha. Also described is a method for the prevention, amelioration and/or treatment of pulmonary inflammation and/or airway hyperresponsiveness comprising administration of a corticosteroid and an oligonucleotide targeted to IL-4R alpha. Further provided are compositions comprising a corticosteroid and an IL-4R alpha targeted antisense oligonucleotide. | 03-04-2010 |
20120088814 | METHODS OF MODULATING AN IMMUNE RESPONSE TO A VIRAL INFECTION - Disclosed herein are methods for treating respiratory disorders via administration of antisense compounds targeting IL-4Rα. Provided herein, for example, are compositions and methods of modulating immune responses to a viral infection in a subject. Also provided, for example, are compositions and methods for managing, treating, ameliorating, preventing and/or delaying the onset of pulmonary inflammation, airway hyperreactivity and/or loss of lung function, or a symptom thereof in a subject during the course of or resulting from a viral infection. Further provided, for example, are compositions and methods of inducing or augmenting hypo-responsiveness, non-responsiveness or tolerance to a virus in a subject. Also provided, for example, are compositions and methods of enhancing the efficacy of a viral vaccine in a subject. In certain embodiments, the compositions and methods provided herein utilize an antisense compound 12 to 35 nucleobases in length targeted to a nucleic acid molecule encoding human IL-4 receptor alpha IL-4Rα, wherein said antisense compound inhibits expression of human IL-4Rα protein and/or expression of functional IL-4 and IL-13 receptors. | 04-12-2012 |
20120316221 | COMPOSITIONS AND THEIR USES DIRECTED TO IL-4R ALPHA - Disclosed herein are compounds, compositions and methods for modulating the expression of IL-4R alpha in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders related to expression of IL 4R-α, airway hyperresponsiveness, and/or pulmonary inflammation. | 12-13-2012 |
Thomas M. Gregory, Cupertino, CA US
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20150350549 | OPTICAL IMAGE STABILIZATION CALIBRATION - In some embodiments, a camera actuator module includes a linear actuator motor for moving a lens assembly, a position sensor coupled to the lens assembly, a mechanical end stop mounted in the path of motion of the lens assembly, and a non-transitory storage medium storing program instructions. In some embodiments, the program instructions are computer-executable to implement exciting, using the linear actuator motor, a mechanical resonance in the camera actuator module calculated to cause the lens assembly to move to an overload displacement by powering the linear actuator of the camera actuator module at a resonant frequency of the camera actuator module, measuring, using the position sensor, a current maximal displacement of the lens assembly during the exciting using a position sensor, and estimating a position of the mechanical end stop using at least the current maximal displacement. | 12-03-2015 |
Trever Gregory, Newport Beach, CA US
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20150352395 | SURFACE MOUNTED MODULAR EXERCISE DEVICE - Described herein are devices and methods which incorporate a surface mounted “base structure” for use with one or more components allowing various resistance-based exercises to be performed, for example, exercises incorporating bars, benches, handles and resistance bands. The device can be made modular such that an intermediate structure can interchangeably cooperate with various components allowing a myriad of different exercises to be performed, utilizing the same single intermediate structure. The device can comprise additional designs and features to enhance the safety and stability of the device and the connections of the various components to the device. | 12-10-2015 |
Wayne Brian Gregory, Fallbrook, CA US
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20080210729 | ERGONOMIC DUTY GEAR BELT - An ergonomic duty gear belt for carrying duty gear components having a first curved conically shaped side section and a second curved conically shaped side section pivotably hinged together and a lumbar pad wrapped around the hinged connection of the belt to provide support for the lumbar area of the wearer. | 09-04-2008 |