Choo, Singapore
Andre Choo, Singapore SG
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20090214490 | HUMAN EMBRYONIC STEM CELL METHODS AND PODXL EXPRESSION - A method of identifying an undifferentiated human embryonic stem cell in a sample which may contain such cells, the method comprising identifying the cell or cells within the sample that express podocalyxin-like protein (PODXL) on their surface. A method of isolating an undifferentiated human embryonic stem cell from a sample containing such cells, the method comprising isolating the cell or cells within the sample that express PODXL on their surface. Typically, the methods use an antibody which binds to PODXL. Undifferentiated human embryonic stem cells isolated by the method may be useful in cell therapy. Also, in particular, compositions of cells differentiated from a human embryonic stem cell but which composition has been depleted of undifferentiated human embryonic stem cells are provided which are useful in cell therapy. | 08-27-2009 |
20100093053 | Microcarriers for Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells. | 04-15-2010 |
20110014693 | Microcarriers For Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells. | 01-20-2011 |
20110294210 | Microcarriers for Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells. | 12-01-2011 |
20120219962 | HUMAN EMBRYONIC STEM CELL METHODS AND PODXL EXPRESSION - A method of identifying an undifferentiated human embryonic stem cell in a sample which may contain such cells, the method comprising identifying the cell or cells within the sample that express podocalyxin-like protein (PODXL) on their surface. A method of isolating an undifferentiated human embryonic stem cell from a sample containing such cells, the method comprising isolating the cell or cells within the sample that express PODXL on their surface. Typically, the methods use an antibody which binds to PODXL. Undifferentiated human embryonic stem cells isolated by the method may be useful in cell therapy. Also, in particular, compositions of cells differentiated from a human embryonic stem cell but which composition has been depleted of undifferentiated human embryonic stem cells are provided which are useful in cell therapy. | 08-30-2012 |
Andre Boon Hwa Choo, Singapore SG
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20090029461 | Immortalised Feeder Cells - The invention relates to an immortalized feeder cell line. The immortalized feeder cell line may be derived from an embryonic fibroblast, which may be a mouse embryonic fibroblast. A culture of an immortalized feeder cell line according to the invention in a suitable culture medium is also provided, as is a composition including an immortalized feeder cell line according to the invention in a suitable carrier or diluent and conditioned medium produced from growth of an immortalized feeder cell line according to the invention. The invention further provides a method of culturing a stem cell including use of a cell line or conditioned medium according to the invention and cells so produced. | 01-29-2009 |
Boon Hwa Andre Choo, Singapore SG
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20080199463 | METHOD FOR TREATING MULTIPLE MYELOMA - The present invention relates to methods for the treatment of multiple myeloma. More particularly, the present invention relates to a method for inducing apoptosis in myeloma cells by administration of a K121-like antibody. | 08-21-2008 |
20090263358 | METHOD FOR TREATING MULTIPLE MYELOMA - The present invention relates to methods for the treatment of multiple myeloma. More particularly, the present invention relates to a method for inducing apoptosis in myeloma cells by administration of a K121-like antibody. | 10-22-2009 |
20110171183 | Markers of Induced Pluripotent Stem Cells - The disclosure relates to the expression of podocalyxin-like protein (PODXL) on the surface of induced pluripotent stem cells and particularly, although not exclusively, to the use of PODXL as a marker of induced pluripotent stem cells. | 07-14-2011 |
20120301899 | USE OF NOVEL MARKERS OF PLURIPOTENT STEM CELLS - The disclosure relates to novel markers of pluripotent stem cells and uses thereof, and particularly, though not exclusively, to antibody molecules based on fragments of mAb84 which bind to undifferentiated pluripotent stem cells via podocalyxin-like protein-1 (PODXL). | 11-29-2012 |
20130115623 | USE OF MARKERS OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS - The disclosure relates to methods of binding and identifying undifferentiated pluripotent stem cells and particularly, although not exclusively, to use of binding moieties which bind to PHB on the surface of undifferentiated pluripotent stem cells, such as PHB-binding peptides, and to methods for depleting undifferentiated stem cells from a sample. | 05-09-2013 |
20130115627 | METHODS FOR IDENTIFYING CANDIDATE CYTOTOXIC ANTIBODY MOLECULES - The disclosure relates to methods for screening candidate antibody molecules which bind to podocalyxin-like protein (PODXL) and/or to undifferentiated pluripotent stem cells and particularly, although not exclusively, to methods for identifying candidate cytotoxic antibody molecules. | 05-09-2013 |
Boon Siang Choo, Singapore SG
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20090125752 | Systems And Methods For Managing A Redundant Management Module - Systems and methods for managing a redundant management module are provided. In this regard, a representative system, among others, includes first and second management modules that are configured to manage a computing device; and a programmable logic device that is configured to: instruct the first management module to manage the computing device responsive to detecting that the first management module is ready to manage the computing device, and instruct the second management module to manage the computing device responsive to detecting that the first management module failed to manage the computing device. | 05-14-2009 |
20120066423 | INTER-INTEGRATED CIRCUIT BUS MULTICASTING - A master node selects a plurality of slave nodes that share a common slave address to receive a data communication. The master node multicasts the data communication to the plurality of selected slave nodes via an inter-integrated circuit bus having a serial data line and a serial clock line. | 03-15-2012 |
20130282949 | ACCESS TO INTERNAL MEMORY OF A COMPUTING DEVICE - A connection is established between a host device and an internal memory of a computing device. A voltage is received by the computing device from the host device. Upon receiving the regulated voltage, the internal memory of the computing device can exchange data with the host device. | 10-24-2013 |
Boo Siang Choo, Singapore SG
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20140292070 | ADAPTER TO PROVIDE POWER FROM A POWER SUPPLY - According to an example, an adapter is to provide power to a plurality of electronic components from a first power supply. The adapter may include a first connector to connect to the first power supply, a plurality of second connectors to connect to the plurality of electronic components, a plurality of lines connecting the first connector to each of the second connectors, in which each of the plurality of electronic components is to receive power from the first power supply through the plurality of lines, and a controller to detect a fault in the receipt of power from a second power supply in an electronic component of the plurality of electronic components and in which the controller is to request allocation of power from the first power supply to supply power to the electronic component. | 10-02-2014 |
Chong Kun Choo, Singapore SG
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20130127603 | MOTOR-DRIVEN CURTAIN OR BLIND ASSEMBLY - Systems and methods for a motor-driven curtain or blind assembly are provided. For example, in some embodiments the motor drive assembly includes a track, a lead runner, and a plurality of sensors. The track can have a plurality of coils that can be electrically activated to generate an electromagnetic field to cause the lead runner to slide along the track. The lead runner may include magnet housing with a magnet to interact with the electromagnetic field. In some embodiments, the plurality of sensors or switches can be disposed between the coils. The sensors can be configured to activate the electromagnetic field locally to cause the lead runner to slide along the track. Examples of the sensors or switches include, but are not limited to, a reed switch, a silicone magnetic switch, an optical switch, a mechanical limit switch, a proximity switch, a magnetic encoder, or an optical encoder. | 05-23-2013 |
20140277749 | MOTORIZED WINDOW COVERING ASSEMBLY - Various embodiments relate to apparatuses and methods of attractive, low cost, controllable, or other featured motorized window covering assemblies. The use of a motor assembly with an integrated WiFi interface enables eliminating a setup box, resulting in lower cost. Eliminating the setup box and any associated wires further eliminates the eye sore that they may pose. These eliminations, along with an elongated motor assembly used in some embodiments, further enable the motor to be made less noticeable by, for example, making it easier to hide or camouflage. As one example, an elongated motor assembly, comprising an elongated casing surrounding the motor and the control board, is hidden inside a window covering holder. An IP address can be assigned to each motor, which enables addressing and controlling each motor individually from any remote device located anywhere with access to the internet. | 09-18-2014 |
Guan Chuan Choo, Singapore SG
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20080276158 | System for Downloading Digital Content Published in a Media Channel - There is provided a system for downloading digital content to a portable media player, the digital content being published in a media channel by a content creator. The system may reside on a server accessible via the Internet. The system may comprise: a data receiver module to receive the digital content from the media channel via a communication medium; a conversion module to convert the received digital content to at least one format for consumption by the player; and a download module to copy the at least one file to the portable media player. The system may further comprise a player detection module to detect file formats compatible with the portable media player. A corresponding method is also disclosed. | 11-06-2008 |
Hong Chean Choo, Singapore SG
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20130069805 | LOW EMI KEYPAD CIRCUITRY - Disclosed is keypad circuitry operable to detect a pressed key while reducing electromagnetic interference (EMI). The keypad circuitry is operable to reduce EMI in two ways: a) reducing the voltage swing occurring at the row circuitry and column circuitry of the keypad, and b) reducing the number of signal transitions by restricting the signal transitions to occurring at the column and row corresponding to a pressed key. By limiting signal transitions to occurring only at the row and column corresponding to a pressed key, fewer signal transitions occur, and thus, less EMI is produced. Additionally, reduced voltage swings at the row circuitry and column circuitry results in reduced EMI. | 03-21-2013 |
Jun Quan Choo, Singapore SG
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20140188135 | Bio-Absorbable Micro-Clip And Applicator For Minimal Access Wound Closure - The present disclosure includes a bio-absorbable wound closure clip for wound closure without crushing of the tissue being closed. The bio-absorbable wound closure clip can be used in minimal access surgery as well as on tissue, such as mucosal tissue, where tactile feedback is reduced. Representative surgical instruments for applying the bio-absorbable wound closure clip and methods of using the same are also provided herein. | 07-03-2014 |
Kim Kian Choo, Singapore SG
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20120244294 | CROSS-LINKING MOIETY - A cross-linking moiety having a general formula I: N | 09-27-2012 |
Li Chia Choo, Singapore SG
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20150318956 | Radio Communication Devices, Access Points, Method for Controlling a Radio Communication Device, and Methods for Controlling an Access Point - According to various embodiments, a radio communication device may be provided. The radio communication device may include: a transmitter configured to transmit a null data packet. The null data packet may include acknowledgement data indicating acknowledgements for a plurality of packets. The null data packet may include a cyclic redundancy check field configured to provide information based on which the null data packet or acknowledgements may be checked for errors. The null data packet may include further information based on which the acknowledgements may be checked for errors. | 11-05-2015 |
Mei Zhen Choo, Singapore SG
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20160124037 | SHORT-CIRCUIT DETECTION CIRCUITS, SYSTEM, AND METHOD - Systems, circuits, and methods for detecting short circuit events during operation of an Insulated-Gate Bipolar Transistor (IGBT) from are provided. A short-circuit detection circuit is described is capable of creating an adaptive blanking time during which a short-circuit detector is blind to short-circuit events for the IGBT and after which the short-circuit detector is allowed to monitor and detect the short-circuit events for the IGBT. | 05-05-2016 |
Poo Dee Choo, Singapore SG
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20090142117 | KEYBOARD WITH EXTENDED CONNECTION - A keyboard for use with a host computer is disclosed. The keyboard has a main portion with a processor and a driver; and an auxiliary portion releasably connected to the main portion and being operatively connected to the processor by a cable. The processor and the driver of the main portion are used for the operation of the auxiliary portion. | 06-04-2009 |
Priscilla Goh Eng Choo, Singapore SG
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20120296304 | Absorbent Article Containing Apertures Arranged in Registration with an Embossed Wave Pattern - An absorbent article that contains a topsheet having embossed regions is provided. The embossed regions propagate in a longitudinal direction of the article in the form of a wave having one or more alternating crests (peaks) and troughs (valleys). Such a wave pattern helps slow down the flow of bodily fluid by directing it along a tortuous path defined by the densified edges rather than in a straight line. Among other things, this reduction in flow rate can help provide sufficient time for the absorbent core to absorb the fluid, which is particularly helpful when it is already partially filled with fluid. Nevertheless, bodily fluids can still sometimes pool near the crests and/or troughs and result in leakage. To help counteract this tendency, the present inventors have discovered that a plurality of apertures can be employed in the topsheet that are arranged in a column that generally extends in a longitudinal direction of the article. At least a portion of the apertures are located proximate to contiguous crests and/or contiguous troughs of the embossed region. Without intending to be limited by theory, it is believed that the registration of the apertures with contiguous crests and/or contiguous troughs of the embossed region puts them in a better position to receive bodily fluids that tend to pool around the embossed regions and thus reduce the likelihood of leakage. | 11-22-2012 |
Quek Leong Choo, Singapore SG
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20090034380 | PARTIAL-BLOCK OFF-TRACK DATA RECOVERY - Techniques for data recovery from a data block wherein portions of the data block are written at different off-track positions are described. For example, portions of a data block can be read separately for each on-track and off-track position in the data block; then, the separately read portions can be recombined into a recovered data block. | 02-05-2009 |
20130046491 | IN-LINE ANALYZER FOR WAVELET BASED DEFECT SCANNING - A method and system for providing simultaneous localization of defects in both the time and frequency domain. A high frequency repeating pattern is written on media, and the pattern is read to generate a readback signal, which is converted into ADC samples. The ADC samples are analyzed, in-line, to determine the type of wavelet, level of decomposition, and threshold level for a wavelet transform of the particular readback signal. The wavelet transform provides details and/or approximations (wavelet coefficients) that are analyzed to determine the type, location, and duration of any identified defects. Any noise in the details and/or approximations (wavelet coefficients) is removed by a wavelet based denoising operation. Flags indicating the type, location, and duration of any defects are generated so that the defects may be mapped. | 02-21-2013 |
Sung Woon Choo, Singapore SG
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20090026568 | OPTICAL COLOR SENSOR SYSTEM - An optical color sensor system is provided including providing a substrate having an optical sensor therein and forming a passivation layer over the substrate. The passivation layer is planarized and color filters are formed over the passivation layer. A planar transparent layer is formed over the color filters and microlenses are formed on the planar transparent layer over the color filters. | 01-29-2009 |
Wee Boon Choo, Singapore SG
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20090028240 | Encoder, Decoder, Method for Encoding/Decoding, Computer Readable Media and Computer Program Elements - An encoder for encoding a first digital signal representative for a first channel and a second digital signal representative for a second channel is described. The encoder comprises cascaded intra-channel prediction elements for compressing the first digital signal and the second digital signal based on intra-channel correlation and an inter-channel prediction element for compressing the first digital signal and the second digital signal based on inter-channel correlation. | 01-29-2009 |
20100023575 | PREDICTOR - A Predictor is described which is based on a modified RLS (recursive least squares) algorithm. The modifications prevent divergence and accuracy problems when fixed point implementation is used. | 01-28-2010 |
Wei Fern Choo, Singapore SG
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20110268913 | Composite Board - A composite board ( | 11-03-2011 |
Wei Hsien Choo, Singapore SG
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20100124766 | Apparatus and Method for Segmented Thermal Cycler - The present invention relates to a thermal cycler for the carrying out of chemical or biological reactions, such as PCR or other nucleic acid amplification reactions, that is segmented with a plurality of reaction vessel receiving elements. The reaction vessel receiving elements are thermally isolated from each other and provide an airtight seal to prevent liquids or moisture from penetrating below the reaction vessel receiving elements. The reaction vessel receiving elements have several recesses arranged in a pattern to receive the reaction vessels of a single standard microtiter plate and the segmented thermal cycler has a system for independently heating and cooling each of the reaction vessel receiving elements. | 05-20-2010 |
20150217292 | Apparatus and Method for Segmented Thermal Cycler - The present invention relates to a thermal cycler for the carrying out of chemical or biological reactions, such as PCR or other nucleic acid amplification reactions, that is segmented with a plurality of reaction vessel receiving elements. The reaction vessel receiving elements are thermally isolated from each other and provide an airtight seal to prevent liquids or moisture from penetrating below the reaction vessel receiving elements. The reaction vessel receiving elements have several recesses arranged in a pattern to receive the reaction vessels of a single standard microtiter plate and the segmented thermal cycler has a system for independently heating and cooling each of the reaction vessel receiving elements. | 08-06-2015 |
Weng Cheong Choo, Singapore SG
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20130190915 | EFFICIENT TRANSFER OF MATERIALS IN MANUFACTURING - Methods for manufacturing automation and a computer executed automated handling system for forming a device are presented. The method includes issuing a transfer request by a tool. The transfer request is processed by a production control system configured for tracking and controlling the flow of carriers. The processing of the transfer request includes selecting a carrier containing production material. A transport system having transport and load/unload (U/L) units in a production area to effect a transfer is controlled and the carrier is transferred by the transport system. | 07-25-2013 |
William Choo, Singapore SG
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20110148981 | DETECTING AND REMOVING FIBERS - In one embodiment, a method to detect and remove fibers comprises identifying blocked nozzles in a grouping of nozzles within a printhead, and triggering a fiber removal event if it is determined that a plurality of adjacent nozzles are blocked. | 06-23-2011 |
Yoo Sang Choo, Singapore SG
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20090217855 | PONTOON-TYPE FLOATING STRUCTURE - A pontoon-type floating structure comprising an upper deck that is to be maintained above water level and that is to receive and support a load by the load resting thereon; and a horizontal array of chambers disposed underneath the upper deck, with the chambers providing a first set of chambers that provide the structure with buoyancy, and a second set of chambers with water having access thereto so that the second set of chambers, under steady state conditions, do not provide buoyancy. | 09-03-2009 |