Patent application number | Description | Published |
20090004279 | Method For Improvement Of Tolerance For Therapeutically Effective Agents Delivered By Inhalation - A method for improvement of tolerance for therapeutically effective agents delivered by inhalation comprising a pretreatment of a patient with a nebulized lidocaine or a lidocaine-like compound administered immediately or up to about thirty minutes before administration of the primary therapeutically effective agent. The pretreatment of the patient with the nebulized lidocaine or a lidocaine-like compound improves airway tolerance and deposition of the agent in the lungs and makes such deposition more safe, efficacious, controllable and predictable. The method of the invention is especially useful for enhancement of deposition of immunosuppressive agents in the lung(s) of transplant patients, improved tolerance of the drugs by reducing cough, and improving pulmonary drug deposition. | 01-01-2009 |
20090041676 | Targeted Delivery of Lidocaine and Other Local Anesthetics and A Method For Treatment of Cough, Asthma and Tussive Attacks - An anti-tussive nebulized solution for targeted delivery of lidocaine into conducting and central airways. A method for treatment of cough and tussive attacks or episodes using said lidocaine solution. A nebulized lidocaine solution administered in daily dose from about 10 mg to 80 mg of lidocaine dissolved in a saline and nebulized into an aerosol having a mass median aerodynamic diameter 3 μm to 10 μm and a geometric standard deviation less than 1.7 using an electronic nebulizer. | 02-12-2009 |
20120093890 | INHALABLE AZTREONAM FOR TREATMENT AND PREVENTION OF PULMONARY BACTERIAL INFECTIONS - A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by | 04-19-2012 |
20120251585 | INHALABLE AZTREONAM LYSINATE FORMULATION FOR TREATMENT AND PREVENTION OF PULMONARY BACTERIAL INFECTIONS - A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by | 10-04-2012 |
20130263852 | FORMULATIONS OF AMINOGLYCOSIDE AND FOSFOMYCIN COMBINATIONS AND METHODS AND SYSTEMS FOR TREATMENT OF VENTILATOR ASSOCIATED PNEUMONIA (VAP) AND VENTILATOR ASSOCIATED TRACHEAL (VAT) BRONCHITIS - The present invention is antibiotic compositions, ventilator based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an in-line nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT. | 10-10-2013 |
20130302423 | Aerosol Formulation of Aminoglycoside and Fosfomycin Combination for Treatment of Ventilator Associated Pneumonia (VAP) and Ventilator Associated Tracheal (VAT) Bronchitis - The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT. | 11-14-2013 |
20130303476 | Aminoglycoside and Fosfomycin Combination for Treatment of Ventilator Associated Pneumonia (VAP) and Ventilator Associated Tracheal (VAT) Bronchitis - The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT. | 11-14-2013 |
20140014107 | Methods to Administer Formulations of Aminoglycoside and Fosfomycin Combination for Treatment of Ventilator Associated Pneumonia (VAP) and Ventilator Associated Tracheal (VAT) Bronchitis - The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT. | 01-16-2014 |
20140037735 | INHALABLE AZTREONAM FOR TREATMENT AND PREVENTION OF PULMONARY BACTERIAL INFECTIONS - A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by | 02-06-2014 |
20140221302 | FORMULATIONS OF AMINOGLYCOSIDE AND FOSFOMYCIN COMBINATIONS AND METHODS AND SYSTEMS FOR TREATMENT OF VENTILATOR ASSOCIATED PNEUMONIA (VAP) AND VENTILATOR ASSOCIATED TRACHEAL (VAT) BRONCHITIS - The present invention is antibiotic compositions, ventilator based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an in-line nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT. | 08-07-2014 |
20150057241 | FORMULATIONS OF AMINOGLYCOSIDES AND FOSFOMYCIN IN A COMBINATION HAVING IMPROVED CHEMICAL PROPERTIES - The present invention is synergistic antibiotic compositions having pH adjusted profiles for manufacturing combination, and administration, particularly for patients at risk or suffering from ventilator-associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis. Antibiotic compositions containing fosfomycin and aminoglycosides having individually predetermined and selected pH ranges are manufactured and stored for in combination prior to aerosolization, preferably with a specially designed in-line nebulizer attached to a ventilator. | 02-26-2015 |
20150057242 | FORMULATIONS OF AMINOGLYCOSIDE AND FOSFOMYCIN COMBINATIONS AND METHODS AND SYSTEMS FOR TREATMENT OF VENTILATOR ASSOCIATED PNEUMONIA (VAP) AND VENTILATOR ASSOCIATED TRACHEAL (VAT) BRONCHITIS - The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT. | 02-26-2015 |
Patent application number | Description | Published |
20080277057 | Composite laminate having a damping interlayer and method of making the same - Composite laminates used in structural applications include an interlayer of soft material that provides damping action to reduce noise and vibration. The interlayer may comprise a viscoelastic material which deforms under stress caused by shock, noise or vibration. A reinforcement may be embedded in the viscoelastic material to maintain the mechanical strength and stiffness of the laminate. The reinforcement may include individual or woven fibers or ridged tubes that provide the interlayer with stiffness. | 11-13-2008 |
20100320319 | SYSTEMS AND METHODS FOR REDUCING NOISE IN AIRCRAFT FUSELAGES AND OTHER STRUCTURES - Systems and methods for reducing noise in aircraft fuselages and other structures are described herein. A noise reduction system configured in accordance with one embodiment of the invention includes an auxetic core, a damping layer, and a constraining layer. In this embodiment, the auxetic core is supported by a structural member, and the damping layer is sandwiched between the auxetic core and the constraining layer. A method for manufacturing a structural assembly in accordance with another embodiment of the invention includes forming a stiffener by positioning a first ply of composite material against a first tool surface, positioning damping material against the first ply, and positioning a second ply of composite material against the damping material to sandwich the damping material between the first and second plies. The method can further include forming a skin by positioning a third ply of composite material against a second tool surface offset from the first tool surface, and attaching the stiffener to the skin by co-curing the first, second and third plies of composite material. | 12-23-2010 |
20120097321 | SYSTEMS AND METHODS FOR REDUCING NOISE IN AIRCRAFT FUSELAGES AND OTHER STRUCTURES - Systems and methods for reducing noise in aircraft fuselages and other structures are described herein. A noise reduction system configured in accordance with one embodiment of the invention includes an auxetic core, a damping layer, and a constraining layer. A method for manufacturing a structural assembly in accordance with another embodiment of the invention includes forming a stiffener by positioning a first ply of composite material against a first tool surface, positioning damping material against the first ply, and positioning a second ply of composite material against the damping material to sandwich the damping material between the first and second plies. The method can further include forming a skin by positioning a third ply of composite material against a second tool surface offset from the first tool surface, and attaching the stiffener to the skin by co-curing the first, second and third plies of composite material. | 04-26-2012 |
20130153145 | SYSTEMS AND METHODS FOR REDUCING NOISE IN AIRCRAFT FUSELAGES AND OTHER STRUCTURES - Systems and methods for reducing noise in aircraft fuselages and other structures are described herein. A noise reduction system configured in accordance with one embodiment of the invention includes an auxetic core, a damping layer, and a constraining layer. In this embodiment, the auxetic core is supported by a structural member, and the damping layer is sandwiched between the auxetic core and the constraining layer. A method for manufacturing a structural assembly in accordance with another embodiment of the invention includes forming a stiffener by positioning a first ply of composite material against a first tool surface, positioning damping material against the first ply, and positioning a second ply of composite material against the damping material to sandwich the damping material between the first and second plies. The method can further include forming a skin by positioning a third ply of composite material against a second tool surface offset from the first tool surface, and attaching the stiffener to the skin by co-curing the first, second and third plies of composite material. | 06-20-2013 |
20150027807 | ACOUSTIC BARRIER SUPPORT STRUCTURE - An acoustic barrier structure can include a support structure that defines a plurality of cells, a weight attached to the support structure, and at least one resonant membrane covering one of the plurality of cells. The at least one resonant membrane can comprise at least one weight. The at least one resonant membrane can have an anti-resonant frequency and the support structure with the weight can provide wide frequency band gaps between odd resonance modes while suppressing structure-membrane coupled modes to enable the anti-resonance of the at least one resonant membrane. | 01-29-2015 |
20150047923 | HYBRID ACOUSTIC BARRIER AND ABSORBER - A hybrid acoustic absorption and reflection resonator can includes a rigid structure defining a cell, a membrane with at least one orifice attached to the rigid structure, and a back sheet attached to the rigid structure and covering the cell. The membrane is configured to reflect acoustic waves in a predetermined range of frequencies. The rigid structure, the membrane, and the back sheet define a Helmholtz cavity; the Helmholtz cavity is configured to absorb acoustic energy at a frequency within the predetermined range of frequencies. | 02-19-2015 |