Llorenc
Llorenc Llopart Prieto, Munich DE
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20130099427 | METHOD AND DEVICE FOR PRODUCING A COMPOSITE MOLDED PART FROM FIBER-REINFORCED PLASTIC - A method for producing a composite molded part from fiber-reinforced plastics material includes providing a prepreg semi-finished product including fibers that are pre-impregnated with a matrix material and encasing the semi-finished product with a flexible sheet material to form an inner arrangement. The flexible sheet material includes a gas-permeable membrane and an inner planar gas-conducting element. The inner arrangement is encased with a first gas-tight casing and positioned on a molding surface of a mold. The inner arrangement and molding surface is encased with a second gas-tight casing. A first negative pressure is applied to the inner planar gas-conducting element and the inside of the first gas-tight casing, and the entire arrangement is heated for a first time at a first temperature. A second negative pressure is applied to an inside of the second gas-tight casing and the entire arrangement is heated for a second time at a second temperature. | 04-25-2013 |
Llorenc Rafecas, Barcelona ES
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20110105443 | SALTS OF MEMANTINE AND COX-INHIBITORS AND THEIR CRYSTAL FORM IN THE TREATMENT OF PAIN - The present invention relates to salts of Memantine and COX-INHIBITORs, their crystal form, the processes for preparation of the same and their uses for the treatment of various disorders, including pain. | 05-05-2011 |
Llorenc Rafecas Jane, Llorenc Del Penedes (tarragona) ES
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20090099367 | Process for preparing a leukotriene antagonist - Process for preparing montelukast or a pharmaceutically acceptable salt thereof, especially its sodium salt, that comprises the condensation of an aldehyde and 7-chloro-2-methylquinoline. Moreover, novel intermediates useful for the synthesis of montelukast are described as well as their preparation. | 04-16-2009 |
Llorenc Rafecas Jané, Barcelona ES
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20110040115 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE - Process for the preparation of aromatic derivatives of 1-adamantane (tricyclo[3.3.1.1 (3,7)]decane), or an acceptable pharmaceutical salt thereof, based on a hydrolysis reaction of a precursor cyano compound. It also comprises different processes for obtaining the cyano compound. It is especially useful for obtaining Adapalene on an industrial scale in high yield and purity. It also comprises new intermediates useful in said preparation process. | 02-17-2011 |
Llorenc Rafecas Jané, Barcelona ES
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20090124577 | Intermediate Compounds for the Preparation of an Angiotensin II Receptor Antagonist - It comprises new substituted 4-valinylmethylphenyl boronic acids of formula (II) and their derivatives and also its preparation process. It also comprises a preparation process of Valsartan (I) from such intermediates. The process comprises the reaction of the new 4-valinylmethylphenyl boronic compounds with a (halophenyl)tetrazole compound which proceeds with high yields. The process is particularly advantageous in its practical industrial realization because it avoids the use of azide derivatives and also the use of expensive biphenyl intermediates. | 05-14-2009 |
20090137841 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE - Process for the obtaining of 1-adamantane (tricycle[3.3.1.1 (3,7)]decane) derivatives, or of a pharmaceutically acceptable salt thereof, based on a carboxylation reaction, via metallation, of a precursor compound with an adequate leaving group. It also comprises the preparation of the precursor compound by means of a selective coupling of the corresponding boron, magnesium or zinc derivative with the corresponding disubstitute aromatic derivative. It is especially useful for the obtaining of Adapalene at industrial scale with good yield and high purity. | 05-28-2009 |
20100010265 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE - Process for the obtaining of 1-adamantane (tricycle[3.3.1.1 (3,7)]decane) derivatives, or of a pharmaceutically acceptable salt thereof, based on a carboxylation reaction, via metallation, of a precursor compound with an adequate leaving group. It also comprises the preparation of the precursor compound by means of a selective coupling of the corresponding boron, magnesium or zinc derivative with the corresponding disubstitute aromatic derivative. It is especially useful for the obtaining of Adapalene at industrial scale with good yield and high purity. | 01-14-2010 |
20110040115 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE - Process for the preparation of aromatic derivatives of 1-adamantane (tricyclo[3.3.1.1 (3,7)]decane), or an acceptable pharmaceutical salt thereof, based on a hydrolysis reaction of a precursor cyano compound. It also comprises different processes for obtaining the cyano compound. It is especially useful for obtaining Adapalene on an industrial scale in high yield and purity. It also comprises new intermediates useful in said preparation process. | 02-17-2011 |
Llorenç Rafecas, Barcellona ES
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20130143890 | CO-CRYSTAL INTERMEDIATES OF ROSUVASTATIN AND METHODS OF USING SAME - Methods for the preparation of Rosuvastatin by co-crystals of Rosuvastatin or intermediates are provided. Also provided are co-crystals, pharmaceutical compositions which include such co-crystals and methods for treating conditions associated with hypercholesterolemia by administering such compositions. | 06-06-2013 |
Llorenç Rafecas Jane, Tarragona ES
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20100298538 | METHOD FOR THE STEREOSELECTIVE PREPARATION OF AMINO ACID DERIVATIVES - The invention relates to a process for the stereoselective preparation of amino acid derivatives, comprising a hydrogenation reaction of the compound of formula (III), alternatively its enantiomer, wherein R is (C | 11-25-2010 |
Llorenç Rafecas Jane, Tarragona ES
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20100298538 | METHOD FOR THE STEREOSELECTIVE PREPARATION OF AMINO ACID DERIVATIVES - The invention relates to a process for the stereoselective preparation of amino acid derivatives, comprising a hydrogenation reaction of the compound of formula (III), alternatively its enantiomer, wherein R is (C | 11-25-2010 |
20140303344 | METHOD FOR THE STEREOSELECTIVE PREPARATION OF AMINO ACID DERIVATIVES - The invention relates to a process for the stereoselective preparation of amino acid derivatives, comprising a hydrogenation reaction of the compound of formula (III), alternatively its enantiomer, wherein R is (C | 10-09-2014 |
Llorenç Rafecas Jané, Barcelona ES
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20120283434 | PROCESS FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF - A process for the preparation of rivaroxaban, or a pharmaceutically acceptable salt thereof, or a solvate thereof, including a hydrate, comprising submitting an amine compound of formula (III) wherein R | 11-08-2012 |