Meissner, US
Alexander Meissner, Cambridge, MA US
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20110076678 | REPROGRAMMING OF SOMATIC CELLS - The disclosure relates to a method of reprogramming one or more somatic cells, e.g., partially differentiated or fully/terminally differentiated somatic cells, to a less differentiated state, e.g., a pluripotent or multipotent state. In further embodiments the invention also relates to reprogrammed somatic cells produced by methods of the invention, to uses of said cells, and to methods for identifying agents useful for reprogramming somatic cells. | 03-31-2011 |
20130296183 | FUNCTIONAL GENOMICS ASSAY FOR CHARACTERIZING PLURIPOTENT STEM CELL UTILITY AND SAFETY - The present invention generally relates set of reference data or “scorecard” for a pluripotent stem cell, and methods, systems and kits to generate a scorecard for predicting the functionality and suitability of a pluripotent stem cell line for a desired use. In some aspects, a method for generating a scorecard comprises using at least 2 stem cell assays selected from: epigenetic profiling, differentiation assay and gene expression assay to predict the functionality and suitability of a pluripotent stem cell line for a desired use. In some embodiments, the scorecard reference data can be compared with the pluripotent stem cells data to effectively and accurately predict the utility of the pluripotent stem cell for a given application, as well as any to identify specific characteristics of the pluripotent stem cell line to determine their suitability for downstream applications, such as for example, their suitability for therapeutic use, drug screening and toxicity assays, differentiation into a desired cell lineage, and the like. | 11-07-2013 |
Benjamin W. Meissner, San Antonio, TX US
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20090033947 | Method for repeatable optical determination of object geometry dimensions and deviations - A method for inspecting geometrical shapes of objects to determine selected dimensions thereof based on data characterizing such objects obtained through stereoscopic photographs taken by a pair of cameras with fields of view intersecting to thereby provide a photographic event measurement volume that includes at least a portion of each of such objects being photographed. The method involves using previously specified procedures to check on the cameras performance consistency in photographing from different positions, preparing the object to be inspected including providing reference point targets thereon, scanning that object with the cameras from different camera pair positions, processing the resulting data to represent the scan basis geometrical shape of the object, and orient it to compare with the dimensional specifications therefor. | 02-05-2009 |
20090089020 | Method of inspecting turbine internal cooling features using non-contact scanners - A method of inspecting an internal feature of a gas turbine component includes removing a portion of the turbine component to expose the internal feature, treating the surfaces of the internal feature to provide the surfaces with a substantially uniform coloration, generating an electronic model of the internal feature, analyzing the electronic model generated with reference to a nominal electronic model, and providing an output based on the analysis of the electronic model generated. | 04-02-2009 |
Callahan Meissner, Lee'S Summit, MO US
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20120040201 | Relocatable Ornaments and Related Methods - Disclosed is an apparatus and related methods of differentiating an item or improving its aesthetic appearance. | 02-16-2012 |
Charles Meissner, Austin, TX US
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20130124920 | METHOD, APPARATUS and product FOR testing transactions - A computer-implemented method and apparatus, comprising: having a plurality of processing entities operating substantially concurrently in a computerized platform enabling transaction operations, wherein the plurality of processing entities comprise two or more entities adapted to store values, and one or more entity adapted to load values, wherein each writing entity is associated with a private memory location within a memory unit; storing symbols into an associated target memory location by each of the entities adapted to store values, wherein symbols are stored according to a predetermined order, wherein a symbol is stored using a transaction; loading a multiplicity of private memory locations by the at least one entity adapted to load values, to obtain loaded values; and analyzing the loaded values for at least one invariant. | 05-16-2013 |
Charles L. Meissner, Austin, TX US
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20080282123 | System and Method of Multi-Frequency Integrated Circuit Testing - A system and method of multi-frequency integrated circuit testing with a method for testing a clocked logic type integrated circuit including creating exerciser code on the integrated circuit when the integrated circuit is operating at a first frequency, switching the integrated circuit to operating at a second frequency greater than the first frequency, and running the exerciser code on the integrated circuit when the integrated circuit is operating at the second frequency. | 11-13-2008 |
Charles Leverett Meissner, Austin, TX US
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20090112557 | System and Method of Automating the Addition of RTL Based Critical Timing Path Counters to Verify Critical Path Coverage of Post-Silicon Software Validation Tools - A system and method for modifying a simulation model and optimizing an application program to produce valid hardware-identified operating conditions that are matched with simulator-identified operating conditions in order to modify a simulator accordingly is presented. A critical path coverage analyzer includes critical path measurement logic into a simulation model that injects errors into the critical path and provides visibility into the number of times that an application program exercises the critical path. The critical path coverage analyzer uses the critical path measurement logic to optimize an application program to adequately exercise and test the critical paths. Once optimized, the critical path coverage analyzer runs the optimized application program on a hardware device to produce hardware-identified operating conditions. The hardware-identified operating conditions are matched against simulator-identified operating conditions. When discrepancies exist, the simulator is modified accordingly to match the hardware-identified operating conditions. | 04-30-2009 |
20110197049 | TWO PASS TEST CASE GENERATION USING SELF-MODIFYING INSTRUCTION REPLACEMENT - A test code generation technique that replaces instructions having a machine state dependent result with special redirection instructions provides generation of test code in which state dependent execution choices are made without a state model. Redirection instructions cause execution of a handler than examines the machine state and replaces the redirection instruction with a replacement instruction having a desired result resolved in accordance with the current machine state. The instructions that are replaced may be conditional branch instructions and the result a desired execution path. The examination of the machine state permits determination of a branch condition for the replacement instruction so that the next pass of the test code executes along the desired path. Alternatively, the handler can execute a jump to the branch instruction, causing immediate execution of the desired branch path. The re-direction instructions may be illegal instructions, which cause execution of an interrupt handler that performs the replacement. | 08-11-2011 |
Christine E. Meissner, Royal Oak, MI US
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20090326806 | Potable Geo-Coded Audio - A method of providing route guidance to a vehicle user via a telematics unit comprises reading geo-coded route data from a removable medium at the telematics unit, the geo-coded data comprising a list of location and events associated with respective actions. The system senses the vehicle location and event status during the course of a trip. If the vehicle location matches a vehicle location listed in the geo-coded route data, the system executes an action associated in the list with that location and if a sensed event status indicates the occurrence of an event listed in the geo-coded route data, the system executes an action associated in the list with that event. | 12-31-2009 |
20100082245 | SYSTEM AND METHOD FOR INDIVIDUALLY UPDATING A LOCATION-BASED GEOMETRIC BOUNDARY OF A SUBSCRIBER VEHICLE - A system and method for individually updating a location-based geometric boundary of a subscriber vehicle that is one of many subscriber vehicles are disclosed herein. The method includes obtaining a garage address of the subscriber vehicle, and determining a location-based geometric boundary of the subscriber vehicle from at least the garage address. The method further includes monitoring at least one of a service event including at least a vehicle registration event, a driving distance, or a driving speed to determine a driving pattern of the subscriber vehicle. The location-based geometric boundary of the subscriber vehicle is dynamically updated based at least on the driving pattern of the subscriber vehicle. | 04-01-2010 |
David C. Meissner, Charlotte, NC US
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20110277591 | SYSTEM AND METHOD FOR REDUCING IRON OXIDE TO METALLIC IRON USING COKE OVEN GAS AND OXYGEN STEELMAKING FURNACE GAS - A process for the direct reduction of iron ore when the external source of reductants is one or both of coke oven gas (COG) and basic oxygen furnace gas (BOFG). Carbon dioxide (CO | 11-17-2011 |
20120125159 | SYSTEM AND METHOD FOR REDUCING IRON OXIDE TO METALLIC IRON USING COKE OVEN GAS AND OXYGEN STEELMAKING FURNACE GAS - A process for reducing iron oxide to metallic iron using coke oven gas (COG), including: a direct reduction shaft furnace for providing off gas; a COG source for injecting COG into a reducing gas stream including at least a portion of the off gas; and the direct reduction shaft furnace reducing iron oxide to metallic iron using the reducing gas stream and injected COG. The COG has a temperature of about 1,200 degrees C. or greater upon injection. The COG has a CH | 05-24-2012 |
20130116347 | SYSTEMS AND METHODS FOR THE USE OF FISCHER-TROPSCH TAIL GAS IN A GAS TO LIQUID PROCESS - The present disclosure provides a Fischer-Tropsch tail gas recycling system, including: a Fischer-Tropsch reactor providing a source of tail gas; a first preheater for preheating the tail gas to between about 200 and 300 degrees C.; a hydrogenator for hydrogenating the tail gas; an expansion device for reducing the pressure of the tail gas to between about 2.5 and 5 bar; a second preheater for preheating a feed gas comprising the tail gas and steam to between about 500 and 600 degrees C.; and a catalytic reformer for reforming the feed gas in the presence of a catalyst, wherein the catalytic reformer operates at about 2 bar and about 1000 degrees C., for example. Optionally, CO2 and/or natural gas are also added to the tail gas and/or steam to form the feed gas. | 05-09-2013 |
20130205951 | METHOD AND SYSTEM FOR THE PRODUCTION OF DIRECT REDUCED IRON USING A SYNTHESIS GAS WITH A HIGH CARBON MONOXIDE CONTENT - Methods and systems for the production of direct reduced iron, including: removing a top gas from a direct reduction furnace; carbon monoxide shifting the top gas using a carbon monoxide shift reactor to form a carbon monoxide shifted top gas having a reduced carbon monoxide content; adding one of a coal gas, a synthesis gas, and an export gas to at least a portion of the carbon monoxide shifted top gas to form a combined gas; removing carbon dioxide from the combined gas using a carbon dioxide removal unit to form a carbon dioxide lean combined gas; and providing the carbon dioxide lean combined gas to the direct reduction furnace as a reducing gas for producing direct reduced iron after heating to reduction temperature. Optionally, the method includes removing carbon dioxide from the top gas using a carbon dioxide removal unit prior to carbon monoxide shifting the top gas. | 08-15-2013 |
20130312571 | SYSTEM AND METHOD FOR REDUCING IRON OXIDE TO METALLIC IRON USING COKE OVEN GAS AND OXYGEN STEELMAKING FURNACE GAS - Novel systems and methods are described for reducing iron oxide to metallic iron in an integrated steel mill or the like that has a coke oven and/or an oxygen steelmaking furnace. More specifically, the present invention relates to novel systems and methods for reducing iron oxide to metallic iron using coke oven gas (COG) or COG and basic oxygen furnace gas (BOFG). | 11-28-2013 |
20140053686 | SYSTEM AND METHOD FOR REDUCING IRON OXIDE TO METALLIC IRON USING NATURAL GAS - In various exemplary embodiments, the present invention provides systems and methods that can convert clean or raw natural gas, clean or dirty coke oven gas, or the like to reducing gas/syngas suitable for direct reduction with minimal processing or cleaning. Hydrocarbons and the like are converted to H | 02-27-2014 |
20140264177 | SYSTEMS AND METHODS FOR GENERATING CARBON DIOXIDE FOR USE AS A REFORMING OXIDANT IN MAKING SYNGAS OR REFORMED GAS - Processes that generate syngas or reformed gas that have the desired H2/CO ratio, such that they can be used directly for producing higher value liquids, such as using a FT GTL process. The systems and methods of the present invention are simpler and more cost effective than conventional systems and methods. The systems and methods of the present invention generate the required CO2 in a reforming furnace by combusting natural gas with a mixture of O2 from an external source and CO2 that is recirculated from a reforming furnace. A second application of the natural gas combustion with external O2 mixed with recirculated CO2 in the reformer burners can be utilized in a DR process. The reformed gas or syngas containing H2 and CO is used to reduce iron oxide to metallic iron in a shaft furnace, for example. | 09-18-2014 |
Dylan Meissner, Seattle, WA US
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20100169487 | DYNAMIC DATA PROCESSING APPLICATIONS WITH MULTIPLE RECORD TYPES AND WORK MANAGEMENT - Methods and apparatuses for defining and executing dynamic applications are disclosed herein. In various embodiments, an electronic library of work management entities is provided. In various embodiments, components are also provided to enable definition of a plurality of record types, definition of a plurality of relationships between selected ones of the work management entities and the record types, including one or more parent-child, reference and reciprocal relationships between selected ones of the record types, to form a dynamic application. In various embodiments, the components are also configured to enable definition of one or more capabilities for a record type, data phasing and workflow manage for the various record types. Other embodiments may also be described and claimed. | 07-01-2010 |
20100169859 | DYNAMIC DATA PROCESSING APPLICATIONS WITH DATA PHASING AND WORK MANAGEMENT - Methods and apparatuses for defining and executing dynamic applications are disclosed herein. In various embodiments, an electronic library of work management entities is provided. In various embodiments, components are provided to enable definition of a plurality of record types, definition of a plurality of data phases for a business lifecycle, behaviors of the record types and selected ones of the work management entities in the various data phases, and workflow rules for the record types and the work management entities to flow through the data phases. The selected ones of the work management entities, the record types, the data phases, behaviors of the record types and the selected ones of the work management entities in the various data phases, and workflow rules for the record types and the selected ones of the work management entities to flow through the data phases, form a dynamic application. Other embodiments may also be described and claimed. | 07-01-2010 |
Jay P. Meissner, Power Springs, GA US
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20150026914 | Carpet cleaning system - A carpet cleaning system having a single, hand-held wand and mounted on it, a pre-spray canister, a venturi tee fluidly connected thereto, and valves for directing pressurized hot water into first and/or second flow streams. Downstream of a flow-splitting tee, a single valve regulates the first flow stream; and a pair of valves, sandwiching the venturi tee, regulate the second flow stream. This pair also controls cleaning solution discharging from the pre-spray canister via the venturi tee. Positioned at the operator's fingertips are the single valve's handle and a bar for moving the paired valves' handles simultaneously, thus allowing one to momentarily turn on or off either flow stream or adjust a mix thereof. Importantly, without interrupting any steam cleaning then in progress, one can immediately reapply the cleaning solution to a stain and, as a consequence, substantially upgrade the quality of the finished carpet cleaning job. | 01-29-2015 |
Jochen Dieter Meissner, Durham, NH US
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20110297023 | APPARATUS AND METHOD FOR PRODUCING NEWSPAPERS FROM A PRINTED WEB - A printing press is provided that includes at least one printing unit printing on a plurality of successive web portions. Each of the web portions is printed with a plurality of groups of pages and each web portion is printed with different content than at least one other of the plurality of web portions. The printing press also includes a storage apparatus receiving the web portions and storing the web portions separately from one another and a folder receiving the web portions from the storage apparatus and processing the web portions into a plurality of printed products. Each of the printed products includes one group of pages from each of the web portions. A method of creating newspapers is also provided. | 12-08-2011 |
Karl J. Meissner, Windham, NH US
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20110138077 | System And Method For Releasing Information From An Information Embargo Setting - Information is electronically transmitted from an information embargo setting. The latency and/or lag in releasing information from the information embargo setting is reduced to facilitate dissemination of the embargoed information faster than other entities. The entity controlling the release of information in the information embargo setting may include one or more of a governmental agency (e.g., associated with the United States government, associated with the Canadian government, associated with the European Union and/or one or more states included therein, and/or other agencies associated with other governments), and/or other entities. | 06-09-2011 |
Len Meissner, Stillwater, MN US
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20090122261 | Reflective Polarized Lenses With High Transmission - The present invention relates to unique reflective polarized lenses that are anti-dazzling and reduce glare. In particular, it relates to polarized lenses utilizing a reflective polarizer, a high-transmission absorptive polarizer and photochromic treatment in a unique combination that can be injection molded to make thermoplastic ophthalmic lenses. The resulting lenses have high luminous transmission, high polarization efficiency for use in sunglasses and has potential applications for night vision | 05-14-2009 |
Manfred Meissner, Minier, IL US
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20120199102 | GAS FUEL ADMISSION SYSTEM FOR A GAS FIRED ENGINE - The present disclosure refers to a gas fuel admission system for a gas fired engine. A gas pressure regulating unit includes a gas pressure regulating unit inlet and a gas pressure regulating unit outlet. The gas pressure regulating unit is configured to receive gas and to discharge the gas at an injection pressure. An engine gas inlet is configured to direct gas into the at least one combustion chamber. A gas admission valve is configured to admit the gas having an injection pressure at a predetermined time for a predetermined duration into the engine gas inlet. A gas pressure relief device is fluidly connected to the gas conduit and it is configured to relieve overpressure of the gas in the gas supply conduit, if a pressure differential between the injection gas pressure and the intake air pressure is above a predetermined threshold. A specific engine control module is configured to control the gas admission valve in response to inputs from various sensing devices. | 08-09-2012 |
Marty Meissner, Milton Freewater, OR US
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20100109283 | OFF-ROAD WHEELCHAIR DEVICE WITH SUSPENSION - An improved off-road wheelchair having detachable wheelchair wheels having disc brakes, an anti-wheelie wheel and at least one detachable stability wheel. | 05-06-2010 |
Michael Meissner, Minneapolis, MN US
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20090063118 | Systems and methods for interactive navigation and visualization of medical images - Systems and methods for visualization and interactive navigation of virtual images of internal organs are provided to assist in medical diagnosis and evaluation of internal organs. In one aspect, an image data processing system ( | 03-05-2009 |
Michael Meissner, Pittsburgh, PA US
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20120069049 | DIGITAL PATHOLOGY IMAGE MANIPULATION - Systems, methods, and products are described that provide for digital pathology image manipulation. One aspect provides for displaying one or more digital specimen images on a display device in one or more viewing windows arranged in one or more viewing configurations; and associating one or more images through one or more correlation processes comprising image co-registration, image locking, and image overlay processes. Other aspects and embodiments are also described herein. | 03-22-2012 |
20140257857 | Systems and Methods in Digital Pathology - A system and method of increasing digital pathology productivity is provided. The system accepts case information from a plurality of sources and pre-processes that information in order to present the slides in an order and orientation dictated by preference and/or reviewing standard. Upon application of the system and method, the appearance and behavior of the user interface is optimized for the user. | 09-11-2014 |
Michael R. Meissner, Ayer, MA US
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20130086338 | LINKING CODE FOR AN ENHANCED APPLICATION BINARY INTERFACE (ABI) WITH DECODE TIME INSTRUCTION OPTIMIZATION - A code sequence made up multiple instructions and specifying an offset from a base address is identified in an object file. The offset from the base address corresponds to an offset location in a memory configured for storing an address of a variable or data. The identified code sequence is configured to perform a memory reference function or a memory address computation function. It is determined that the offset location is within a specified distance of the base address and that a replacement of the identified code sequence with a replacement code sequence will not alter program semantics. The identified code sequence in the object file is replaced with the replacement code sequence that includes a no-operation (NOP) instruction or having fewer instructions than the identified code sequence. Linked executable code is generated based on the object file and the linked executable code is emitted. | 04-04-2013 |
20130086570 | LINKING CODE FOR AN ENHANCED APPLICATION BINARY INTERFACE (ABI) WITH DECODE TIME INSTRUCTION OPTIMIZATION - A code sequence made up multiple instructions and specifying an offset from a base address is identified in an object file. The offset from the base address corresponds to an offset location in a memory configured for storing an address of a variable or data. The identified code sequence is configured to perform a memory reference function or a memory address computation function. It is determined that the offset location is within a specified distance of the base address and that a replacement of the identified code sequence with a replacement code sequence will not alter program semantics. The identified code sequence in the object file is replaced with the replacement code sequence that includes a no-operation (NOP) instruction or having fewer instructions than the identified code sequence. Linked executable code is generated based on the object file and the linked executable code is emitted. | 04-04-2013 |
Oliver Robert Meissner, Washington, DC US
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20140237377 | GRAPHICAL USER INTERFACE METHODS TO DETERMINE AND DEPICT RELATIVE POPULARITY OF INTERNET OFFERINGS - The present invention relates generally w a method to enable computerized device users, Internet service and product providers, media companies and others to be aware of the relative popularity of offerings, such as media, other digital files, products, services, representations of people and other items, available is the Internet, including through mobile applications (offerings), through a simple, easy to view graphical user interface (GUI) which can be viewed on computer platforms such as desktop, tablet and laptop computers, smart phones, head and wrist mounted computers and other devices. Based on number of web-hits to, selections of addition to or subtraction from a favorites database, number of purchases of, duration of viewing, listening to, or otherwise experiencing a certain offering by a user, or combination thereof, the offering's popularity rank is dearly graphically depicted and updated in real time, or regularly, with the capability to view the offering popularity relative to other offerings in a certain database of offerings. The GUI may be interactive with down-select options and possibility to zoom in and out to small or large numbers of offerings represented therein. | 08-21-2014 |
Paul S. Meissner, Barnesville, MD US
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20100130417 | TRANSFORMING GROWTH FACTOR ALPHA HII - The present invention discloses transforming growth factor alpha HII polypeptides and polynucleotides encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and therapeutic uses of the polypeptides which include stimulating wound healing, treating neurological disorders, treating ocular disorders, treating kidney and liver disorders, and stimulating embryogenesis and angiogenesis. Also disclosed are antagonists against such polypeptides and their use as a therapeutic to treat neoplasia. Also disclosed are diagnostic assays for detecting altered levels of the polypeptide of the present invention and mutations in the nucleic acid sequences which encode the polypeptides of the present invention. | 05-27-2010 |
Richard Meissner, Newberg, OR US
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20090146965 | INTERACTIVE COMMUNICATION SYSTEM HAVING AN INTEGRATED KEY DRIVE SYSTEM - A device and method of connecting an interactive communication system to a processing device. The device is a cable system that includes first and second ends. The first end of the cable system has a leg connector, while the second end of the connector system has first and second arm connectors. The method implements the cable system to load or run software onto the processing device, and includes connecting the leg connector to an interactive communication system; connecting the first arm connector having a memory device to the processing device, wherein the memory device includes predetermined software; loading/running the software on the processing device; disconnecting the first arm connector having the memory device from the processing device; and connecting a second arm connector to the processing device. | 06-11-2009 |
20100275132 | INTERACTIVE COMMUNICATION SYSTEMS - The present invention includes interactive communication systems that incorporate several beneficial embodiments including an interactive tray system, an electronic presentation messaging system, an interactive podium, and a key drive system. The interactive tray system enables a single, transferable interactive unit to be fastened to a communication medium, turning into a fully interactive medium. The electronic presentation messaging system enables the e-mailing of presentations and notes to and from components of the interactive communication system. The interactive podium increases conventional podium mobility, enabling both the presenter, and podium, to move and be moved about the room without attention to wired connections. The key drive system replaces the conventional Y-connector of the key drive technology by effectively integrating the key drive in the device, thus only having one connector, and eliminating the need to change connectors from the key drive, to the USB connector, upon software driver loading. | 10-28-2010 |
Richard K. Meissner, Hartland, WI US
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20080300111 | Artificial rock climbing systems and methods adapted for water environment - Improved climbing structures, systems, and methods for use on an artificial rock climbing arrangement which includes a generally rigid framework removably attached to a support surface located adjacent a body of water. The framework makes use of assist shocks in combination with actuators in order to provide an automated (motorized) easy-up vertical climbing wall. A panel structure is mounted on the framework for defining a climbing surface, the panel surface carrying a plurality of climbing holds. A hinged adjustable support bar is secured between the framework and the support surface for maintaining the framework and the climbing surface in a substantially vertical orientation when a climber scales the climbing surface. The hinged adjustable support bar is diagonally mounted with telescoping and threaded ends. | 12-04-2008 |
Robert Meissner, Schwenksville, PA US
Robert Meissner, Devon, PA US
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20140309227 | QUINOLINE CARBOXAMIDE AND QUINOLINE CARBONITRILE DERIVATIVES AS mGluR2-NEGATIVE ALLOSTERIC MODULATORS, COMPOSITIONS, AND THEIR USE - The present invention provides quinoline carboxamide and quinoline carbonitrile compounds of formula (I) wherein ring A, R | 10-16-2014 |
Robert Joseph Meissner, Brooklyn Park, MN US
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20090276322 | RETAILER DEBIT CARD SYSTEM - Methods for soliciting and enrolling customers for a retailer payment instrument are disclosed. For example, a method is disclosed for enrolling a customer for a retailer debit card which includes receiving enrollment data from the customer, establishing a check writer rating for the customer based on a history of checks associated with the customer and stored by the retailer, adjusting a validation threshold score based on the check writer rating, and denying enrollment of the customer if the validation score is less than the adjusted validation threshold score. Other associated methods and systems are also disclosed. | 11-05-2009 |
20120143747 | RETAILER DEBIT CARD SYSTEM - Methods for soliciting and enrolling customers for a retailer payment instrument are disclosed. For example, a method is disclosed for enrolling a customer for a retailer debit card which includes receiving enrollment data from the customer, establishing a check writer rating for the customer based on a history of checks associated with the customer and stored by the retailer, adjusting a validation threshold score based on the check writer rating, and denying enrollment of the customer if the validation score is less than the adjusted validation threshold score. Other associated methods and systems are also disclosed. | 06-07-2012 |
20130232004 | RETAILER DEBIT CARD SYSTEM - A method of processing a purchase transaction for one or more items includes receiving, at a central computing network, MICR information associated with a financial account of a customer. The central computing network includes a solicitation processor and a comprehensive negative check file. The method further includes using the solicitation processor to determine whether to solicit the customer to apply for a financial transaction card including determining if any of a plurality of predefined reasons exist not to solicit the customer, wherein one of the plurality of predefined reasons includes if the MICR information associated with the financial account of the customer matches MICR information of a check listed in the comprehensive negative check file, if any of the plurality of predefined reasons exist, deciding not to solicit the customer, and if none of the plurality of predefined reasons exist, deciding to solicit the customer. | 09-05-2013 |
Robert S. Meissner, Schwenksville, PA US
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20090082320 | Fluorinated 4-azasteroid derivatives as androgen receptor modulators - Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. They are useful as agonists of the androgen receptor in bone and/or muscle tissue while antagonizing the AR in the prostate of a male patient or in the uterus of a female patient. These compounds are therefore useful in the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, cancer cachexia, muscular dystrophies, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents. | 03-26-2009 |
20090088458 | N-(Pyridin-4-Yl)-2-Phenylbutanamides as Androgen Receptor Modulators - Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal adiposity, metabolic syndrome, type II diabetes, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents. | 04-02-2009 |
20090275515 | 2-HYDROXY-2-PHENYLTHIOPHENYLPROPIONAMIDES AS ANDROGEN RECEPTOR MODULATORS - Compounds of structural formula (I) are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HFV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal adiposity, metabolic syndrome, type II diabetes, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents. | 11-05-2009 |
20090306202 | D-homoandrosta-17-yl carbamate derivatives as selective glucocorticoid receptor ligands - The present invention is directed to D-homoandrosta-17-yl-carbamate derivatives as selective glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 12-10-2009 |
20110003797 | HEXAHYDROCYCLOPENTYL[f]INDAZOLE CARBOXAMIDES AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS - The present invention is directed to hexahydrocyclopentyl[f]imidazole carboxamides and derivatives thereof as selective glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 01-06-2011 |
20110105440 | HEXAHYDROCYCLOPENTYL[f]INDAZOLE SULFONAMIDES AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS - The present invention is directed to hexahydrocyclopentylf]indazole carboxamides and derivatives thereof as selective glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 05-05-2011 |
20120214847 | 2-[1-PHENYL-5-HYDROXY-4a-SUBSTITUTED-HEXAHYDROCYCLOPENTA[F]INDAZOL-5-YL]ET- HYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS - The present invention encompasses compounds of Formula I: or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 08-23-2012 |
Robert S. Meissner, Devon, PA US
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20120172397 | HEXAHYDROCYCLOPENTA[f]INDAZOLE 5-YL ETHANOLS AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS - The present invention encompasses compounds of Formula (I) or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 07-05-2012 |
20120214846 | HEXAHYDROCYCLOPENTYL[F]INDAZOLE PYRIDYL ETHANOLS AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS - The present invention encompasses compounds of Formula (I): or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 08-23-2012 |
Sandra Meissner, Secaucus, NJ US
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20140288278 | CHROMATOGRAPHY PROCESS FOR RESOLVING HETEROGENEOUS ANTIBODY AGGREGATES - Disclosed are methods and processes utilizing multi-modal chromatography as a polishing step to separate heterogeneously charged (basic and acidic) aggregates and other impurities from partially a partially purified bulk product monoclonal antibody product. The resulting chromatographic process provides a scaleable production process that is cost effective and increases the productivity of the purification process over a platform utilizing a combination of anion and cation exchange chromatography to resolve heterogeneous aggregates. | 09-25-2014 |
Stark Meissner, Prattville, AL US
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20100042536 | System and method of transferring funds - A system for transferring funds can include a database with information about a routing number including ACH transfer information and wire transfer information. The system can include a conversion module configured to receive an ACH transfer file including an associated routing number, access the database to retrieve wire transfer information, and convert the ACH transfer file to a wire transfer file. The system can include an implementation module configured to perform a wire transfer using the wire transfer file. The wire transfer can be a batch wire transfer. The conversion module can use the associated routing number from the ACH transfer file to retrieve wire transfer information for the associated routing number from the database. | 02-18-2010 |
Stephen C. Meissner, West Henrietta, NY US
Patent application number | Description | Published |
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20080259634 | DOUBLE-SIDED TURNING FILM - A backlight device for a display comprising (1) a side-lit light source, (2) a light guide plate and (3) a turning film comprising a light entry and a light exit surface comprising lenticular elements on the exit surface and prismatic structures on the entry surface, wherein the average values of the parameters of the features and the thickness of the film are selected to provide a peak output angle of ±10° from normal to the light exit surface of the light guide plate and an optical gain of at least 1.25. Also disclosed are methods of making the turning film and a display incorporating the backlight. | 10-23-2008 |
Steven A. Meissner, Power Springs, GA US
Patent application number | Description | Published |
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20150026914 | Carpet cleaning system - A carpet cleaning system having a single, hand-held wand and mounted on it, a pre-spray canister, a venturi tee fluidly connected thereto, and valves for directing pressurized hot water into first and/or second flow streams. Downstream of a flow-splitting tee, a single valve regulates the first flow stream; and a pair of valves, sandwiching the venturi tee, regulate the second flow stream. This pair also controls cleaning solution discharging from the pre-spray canister via the venturi tee. Positioned at the operator's fingertips are the single valve's handle and a bar for moving the paired valves' handles simultaneously, thus allowing one to momentarily turn on or off either flow stream or adjust a mix thereof. Importantly, without interrupting any steam cleaning then in progress, one can immediately reapply the cleaning solution to a stain and, as a consequence, substantially upgrade the quality of the finished carpet cleaning job. | 01-29-2015 |
Steven Allen Meissner, Power Springs, GA US
Patent application number | Description | Published |
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20150026914 | Carpet cleaning system - A carpet cleaning system having a single, hand-held wand and mounted on it, a pre-spray canister, a venturi tee fluidly connected thereto, and valves for directing pressurized hot water into first and/or second flow streams. Downstream of a flow-splitting tee, a single valve regulates the first flow stream; and a pair of valves, sandwiching the venturi tee, regulate the second flow stream. This pair also controls cleaning solution discharging from the pre-spray canister via the venturi tee. Positioned at the operator's fingertips are the single valve's handle and a bar for moving the paired valves' handles simultaneously, thus allowing one to momentarily turn on or off either flow stream or adjust a mix thereof. Importantly, without interrupting any steam cleaning then in progress, one can immediately reapply the cleaning solution to a stain and, as a consequence, substantially upgrade the quality of the finished carpet cleaning job. | 01-29-2015 |
Timothy A. Meissner, Power Springs, GA US
Patent application number | Description | Published |
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20150026914 | Carpet cleaning system - A carpet cleaning system having a single, hand-held wand and mounted on it, a pre-spray canister, a venturi tee fluidly connected thereto, and valves for directing pressurized hot water into first and/or second flow streams. Downstream of a flow-splitting tee, a single valve regulates the first flow stream; and a pair of valves, sandwiching the venturi tee, regulate the second flow stream. This pair also controls cleaning solution discharging from the pre-spray canister via the venturi tee. Positioned at the operator's fingertips are the single valve's handle and a bar for moving the paired valves' handles simultaneously, thus allowing one to momentarily turn on or off either flow stream or adjust a mix thereof. Importantly, without interrupting any steam cleaning then in progress, one can immediately reapply the cleaning solution to a stain and, as a consequence, substantially upgrade the quality of the finished carpet cleaning job. | 01-29-2015 |
Torsten B. Meissner, Boston, MA US
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20130177577 | NLRC5 AS A TARGET TO INTERVENE MHC CLASS 1-MEDIATED IMMUNE RESPONSES - A method to modulate MHC class I gene expression by modulating NLRC5 expression and/or NLRC5 activity in a subject is provided. The method comprises administering to the subject a compound HLA-A HLA-B that modulates NLRC5 expression and/or NLRC5 activity in an amount effective to modulates MHC class I gene expression. Also described is a screen for compounds that modulate NLRC5 expression. Candidate compounds are tested for their ability to modulate NLRC5 expression. | 07-11-2013 |