Patent application number | Description | Published |
20090148436 | ANTIBODY TO GDF8 AND USES THEREOF - The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF8), in particular epitopes specific to GDF8 and other specific antagonists of GDF8 in particular anti-GDF8 antibodies or antigen binding protein or fragment thereof which may inhibit GDF8 activity and signal in vitro and/or in vivo. The disclosure also provides for an immunoassay used to detect and quantitate GDF8. The disclosure also provides methods for diagnosing, preventing, ameliorating, and treating GDF8-associated disorders, e.g., degenerative orders of muscle, bone, and insulin metabolism. Finally, the disclosure provides pharmaceuticals for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention. | 06-11-2009 |
20100074935 | RECOMBINANT LUBRICIN MOLECULES AND USES THEREOF - Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided. | 03-25-2010 |
20100080848 | Recombinant Lubricin Molecules and Uses Thereof - Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided. | 04-01-2010 |
20110189731 | POLYNUCLEOTIDES ENCODING RECOMBINANT LUBRICIN MOLECULES AND USES THEREOF - Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided. | 08-04-2011 |
20130196930 | POLYNUCLEOTIDES ENCODING RECOMBINANT LUBRICIN MOLECULES AND USES THEREOF - Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided. | 08-01-2013 |
20140023638 | ANTIBODY TO GDF8 AND USES THEREOF - The disclosure provides novel molecules related to growth and differentiation factor 8 (GDF8), in particular epitopes specific to GDF8 and other specific antagonists of GDF8 in particular anti GDF8 antibodies or antigen binding protein or fragment thereof which may inhibit GDF8 activity and signal in vitro and/or in vivo. The disclosure also provides for an immunoassay used to detect and quantitate GDF8. The disclosure also provides methods for diagnosing, preventing, ameliorating, and treating GDF8 associated disorders, e.g., degenerative orders of muscle, bone, and insulin metabolism. Finally, the disclosure provides pharmaceuticals for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention. | 01-23-2014 |
Patent application number | Description | Published |
20100010655 | ASSEMBLY CONNECTION METHOD FOR ATTACHING VIRTUAL PARTS IN A COMPUTER AIDED DESIGN SOFTWARE ENVIRONMENT - A method and apparatus that allows the user of a computer aided design (CAD) system to connect three-dimensional parts to create a three-dimensional assembly using connections that completely define the attachment between the parts attached to each other by that connection. The user can simultaneously define the orientations of the parts and their behavior. “Behavior” includes whether parts are rigidly connected or allowed to move relative to one and other, and if allowed to move, the nature and limits on that movement. Within any movement allowed, the user may specify key discrete orientations known to be important to the function of the assembly, such as orientations that limit movement within the assembly. The connection method creates a smaller, more consistent representation of the underlying constraints of the assembly, improving the reliability, performance, and ease of use of a CAD system in which it is used. | 01-14-2010 |
20100060635 | ASSEMBLY-BASED PARAMETRIC MODELER - Presently disclosed is a process and system for assembly-based parametric modeling having a single design environment in which the parts, components, and assemblies thereof may be designed concurrently. In embodiments of the present invention, every assembly has a deterministic parametric history supporting both top-down and bottom-up assembly design methodologies. Top-down components may be built in place, reducing the user interaction required to define the attachment and movement characteristics of the assembly. Bottom-up components may be inserted into an assembly using a parametric Insert Component Feature. The process and system also provides the ability to parametrically define the shape of an assembly in multiple orientations that still regenerate deterministically. | 03-11-2010 |
Patent application number | Description | Published |
20090308000 | HIGH DENSITY STORAGE FACILITY - A high density storage facility including a storage area is described. Storage racks may be provided in the storage facility, and may be divided from top to bottom into slots. The slots may extend the width of the racks and be accessible for inserting and removing objects into and from the racks. The racks may be disposed in rows within the storage area and include a mechanism for rolling the racks along the storage area. The storage area may include a wall disposed substantially parallel to a widthwise side of the storage area. Doors may be disposed along the length of the wall, for providing access to the width ends of the racks. The racks may be installed upon rollably movable carriages along the width of the storage area for providing access to the width ends of the carriage racks from the doors. | 12-17-2009 |
20120251277 | High Density Storage Facility - A high density storage facility including a plurality of rows of independently movable carriage racks, each row having a plurality of the independently movable carriage racks. Each carriage rack has a height, a length and a width, and defines a plurality of tiers, each tier defining at least one storage slot, the slots extending substantially the length of the carriage racks and being substantially open and accessible for inserting and removing objects into and from the width ends of the carriage racks. The carriage racks are disposed within the floor area and are independently movable along the floor in a direction consistent with the width of the floor area. Preferably, the carriage racks are arranged in the rows within the floor area with the lengthwise sides of the carriage racks being arranged substantially parallel to the lengthwise sides of the floor area. | 10-04-2012 |
20140158908 | Container Scanning System and Method - A system and method of scanning a number of objects such as crates or intermodal containers in a storage area having a plurality of movable racks, each rack occupying at least one level and capable of carrying at least one object. The racks are capable of being moved to establish successive vacant multi-level aisles among the racks. At least one scanner is movable substantially vertically within the successive vacant aisles to scan successive objects substantially adjacent to each vacant aisle to detect at least one pre-determined characteristic. | 06-12-2014 |