Vrijbloed
Jan Willem Vrijbloed, Mohlin CH
Patent application number | Description | Published |
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20120208765 | MODIFIED AGRIN-FRAGMENT CAPABLE OF RESTORING MUSCLE STRENGTH FOR USE AS A MEDICAMENT - Modified agrin fragment having in vivo activity, comprising at least the domains LG2 and LG3 of human agrin in covalently interlinked form and modified in such a way that the fragment cannot be cleaved by neurotrypsin for use as medicament. | 08-16-2012 |
20130245064 | NOVEL NEUROTRYPSIN INHIBITORS - The invention relates to novel acylamino-hydroxy-benzamides of formula (I), wherein R | 09-19-2013 |
20130261130 | NEUROTRYPSIN INHIBITORS - The invention relates to acylamino-phthalic acid amides and related compounds of formula (I) wherein A is —CON—R | 10-03-2013 |
20130344593 | METHOD FOR THE PRODUCTION OF HYBRIDOMA CELL LINES PRODUCING MONOCLONAL ANTIBODIES CAPABLE TO SPECIFICALLY BINDING TO A HUMAN C44-FRAGMENT OF AGRIN - A method for the production of a hybridoma cell lines producing monoclonal antibodies capable to specifically binding to a human C44-fragment of agrin, comprising administering to wild-type-mice an immunizing amount of C44y≧4-fragment of agrin, isolating antibody producing cells from the immunized mice, fusing them with a myeloma cell line, growing the fused cells in a selection medium, screening the antibodies in the supernatants of hybridoma cells for binding to C44-fragment of agrin and isolating the hybridoma cells producing the desired monoclonal antibodies | 12-26-2013 |
20150031057 | METHOD FOR THE DETERMINATION OF RENAL FUNCTION - Method for the determination of the renal function wherein the amount of at least one agrin fragment derived by neurotrypsin cleavage of agrin is measured in a sample taken from a patient and the measured amount of the agrin-fragment in the sample is used as indicator for renal function. | 01-29-2015 |
Jan Wim Vrijbloed, Zurich CH
Patent application number | Description | Published |
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20090118134 | Template Fixed Beta-Hairpin Loop Mimetics and Their Use in Phage Display - Template-fixed β-hairpin mime tics of the general formula R | 05-07-2009 |
20100056432 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIBACTERIAL ACTIVITY - Template-fixed β-hairpin peptidomimetics of the general formula (I) wherein Z is a template-fixed chain of | 03-04-2010 |
20110294702 | TEMPLATE FIXED BETA-HAIRPIN LOOP MIMETICS AND THEIR USE IN PHAGE DISPLAY - Template-fixed β-hairpin mimetics and libraries including a plurality of these mimetics are provided. The template-fixed β-hairpin mimetics are of the following general formula: | 12-01-2011 |
20110319291 | TEMPLATE FIXED BETA-HAIRPIN LOOP MIMETICS AND THEIR USE IN PHAGE DISPLAY - Template-fixed β-hairpin mimetics and libraries including a plurality of these mimetics are provided. The template-fixed β-hairpin mimetics are of the following general formula: | 12-29-2011 |
Jan Wim Vrijbloed, Moehlin CH
Patent application number | Description | Published |
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20100048463 | TEMPLATE-FIXED PEPTIDOMIMETICS - The template-fixed B-hairpin peptidomimetics Cyclo(-Tyr-His-X-Cys-Ser-Ala- | 02-25-2010 |
20130150299 | TEMPLATE-FIXED PEPTIDOMIMETICS - The template-fixed β-hairpin peptidomimetics Cyclo(-Tyr-His-X-Cys-Ser-Ala- | 06-13-2013 |
20150080317 | TEMPLATE-FIXED PEPTIDOMIMETICS - The template-fixed B-hairpin peptidomimetics Cyclo(-Tyr-His-X-Cys-Ser-Ala- | 03-19-2015 |
Jan Wim Vrijbloed, Mohlin CH
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20110245155 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH CXCR4 ANTAGONIZING ACTIVITY - Template-fixed β-hairpin peptidomimetics of the general formula (I) | 10-06-2011 |
20150087577 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH CXCR4 ANTAGONIZING ACTIVITY - Template-fixed β-hairpin peptidomimetics of the general formula (I) | 03-26-2015 |
Wim Vrijbloed, Moehlin CH
Patent application number | Description | Published |
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20100240592 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIMICROBIAL ACTIVITY - Template-fixed β-hairpin peptidomimetics of the general formula (I) wherein Z is a template-fixed chain of 12 α-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid) are Gly, or Pro, or of certain types which, as the remaining Symbols in the above formula, are defined in the description and the claims, and salts thereof, have the property to selectively inhibit the growth of or to kill microorganisms such as | 09-23-2010 |
20140087994 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIMICROBIAL ACTIVITY - Template-fixed β-hairpin peptidomimetics of the general formula | 03-27-2014 |
20140187471 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIMICROBIAL ACTIVITY - Template-fixed β-hairpin peptidomimetics of the general formula | 07-03-2014 |
20140187472 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIMICROBIAL ACTIVITY - Template-fixed β-hairpin peptidomimetics of the general formula | 07-03-2014 |