Konietzko
Albrecht Konietzko, Bamberg DE
Patent application number | Description | Published |
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20120269029 | PROGRAMMABLE MIXER AND METHOD FOR THE OPERATION THEREOF - The invention relates to a programmable mixer for producing pharmaceutical or cosmetic recipes. The mixer includes a controller, a motor-driven mixing unit having a mixing tool engaging in a mixing vessel, and a lift unit. The lift unit induces an axial relative motion between the mixing tool and the mixing vessel to displace the mixing tool in the mixing vessel at a constant lift speed. The control method includes counting the lift strokes performed by the lift unit during an initial mixing process for each mixing period, and using the identifying data determined in the initial mixing process during a repeated mixing process. The identification data matching the recipe are read in, and the number of lift strokes per mixing period determined in the initial stirring process is used for implementing the corresponding mixing period of the repeated mixing process. | 10-25-2012 |
Janelle Konietzko, Lansdale, PA US
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20140288278 | CHROMATOGRAPHY PROCESS FOR RESOLVING HETEROGENEOUS ANTIBODY AGGREGATES - Disclosed are methods and processes utilizing multi-modal chromatography as a polishing step to separate heterogeneously charged (basic and acidic) aggregates and other impurities from partially a partially purified bulk product monoclonal antibody product. The resulting chromatographic process provides a scaleable production process that is cost effective and increases the productivity of the purification process over a platform utilizing a combination of anion and cation exchange chromatography to resolve heterogeneous aggregates. | 09-25-2014 |
Matthias Konietzko, Bamberg DE
Patent application number | Description | Published |
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20120269029 | PROGRAMMABLE MIXER AND METHOD FOR THE OPERATION THEREOF - The invention relates to a programmable mixer for producing pharmaceutical or cosmetic recipes. The mixer includes a controller, a motor-driven mixing unit having a mixing tool engaging in a mixing vessel, and a lift unit. The lift unit induces an axial relative motion between the mixing tool and the mixing vessel to displace the mixing tool in the mixing vessel at a constant lift speed. The control method includes counting the lift strokes performed by the lift unit during an initial mixing process for each mixing period, and using the identifying data determined in the initial mixing process during a repeated mixing process. The identification data matching the recipe are read in, and the number of lift strokes per mixing period determined in the initial stirring process is used for implementing the corresponding mixing period of the repeated mixing process. | 10-25-2012 |
Thomas Konietzko, Niederkassel DE
Patent application number | Description | Published |
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20140170876 | ARRANGEMENT FOR ESTABLISHING AND BREAKING A CONNECTION BETWEEN A PLUG AND A MATING PLUG - Arrangement for establishing and/or breaking a connection between a plug and a complementary mating plug, wherein a lever which can be pivoted about an axis is arranged on the plug. The connection between the plug and the mating plug can be broken when the lever is pivoted into a disconnection position and/or can be established when the lever is pivoted into a connection position. The plug is, in particular, a switch module, for example a tripping module for a mating plug which is in the form of a circuit breaker. | 06-19-2014 |
20140179142 | SWITCH ARRANGEMENT FOR ESTABLISHING AND/OR DISCONNECTING A CONNECTION BETWEEN A CONNECTOR AND A MATING-CONNECTOR - A switching arrangement includes a plug and a complementary mating plug for establishing and separating a connection between the plug and the mating plug. The plug includes a locking bolt disposed rotationally about an axis. The locking bolt includes a thread and the mating plug includes a mating thread. The plug is lockable to the mating plug by driving in the thread of the locking bolt into the mating thread. The switching device is configured to be moved to a connected position by driving in the thread of the locking bolt into the mating thread, and thereby providing a movement of the plug relative to the mating plug, and is configured to be moved to a disconnected position by driving out the thread of the locking bolt from the mating thread, thereby providing the movement of the plug relative to the mating plug. | 06-26-2014 |
Uwe Konietzko, Zurich CH
Patent application number | Description | Published |
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20100169988 | MEANS AND METHODS FOR ISOLATING AND DETERMINING NOVEL TARGETS FOR THE TREATMENT OF NEURODEGENERATIVE, NEUROLOGICAL OR NEUROPSYCHIATRIC DISORDERS AND COMPOSITIONS COMPRISING THE SAME - A novel method of identifying and obtaining molecules interacting with neurodegenerative, neurological or neuropsychiatric disorder-associated proteins is provided, which is suitable for drug screening and drug development. Furthermore, drugs and drug targets for the therapeutic intervention of neurodegenerative, neurological or neuropsychiatric disorders, in particular Alzheimer's disease are described. | 07-01-2010 |
Uwe Konietzko, Konstanz DE
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20090117120 | Transgenic animal model for alzheimer's disease - Provided is a novel APP (amyloid precursor protein) transgenic non-human animal modeling in vivo the pathophysiological effects and effects on cognitive behavior of early intraneuronal and extracellular brain parenchymal amyloid-β (Aβ) deposition and cerebral amyloid angiopathy associated with brain microhemorrhages and reduced vasoreactivity and blood flow. Furthermore, methods of screening for therapeutic or diagnostic agents useful in the treatment or diagnosis of Alzheimer's disease, in particular for improving blood flow to the brain are provided as well as the corresponding therapeutic methods. | 05-07-2009 |