Patent application number | Description | Published |
20120277873 | Interbody fusion device with lipped anterior plate and associated methods - A method and apparatus is provided for use in spinal fusion procedures. An interbody fusion device has a first piece that is a load bearing device designed to bear the axial loading from the end plates of adjacent vertebrae. A second piece of the interbody fusion device is a retention device whose function is to prevent migration of the load bearing device. One or more fasteners secure the retention device to the vertebrae above and below the load bearing device. The fasteners cause the end plates of the vertebrae to compress the end plates to the load bearing device to facilitate proper fusion. The second piece can be configured to include lips that abut the apothyseal rings during, with the plate including bores angled such that fasteners penetrate the apothyseal rings. | 11-01-2012 |
20130261666 | INTERSPINOUS FIXATION DEVICE - A method of securing a portion of a spine is disclosed that includes preparing a first tunnel through a first spinous process and a second tunnel through a second spinous process of a spine, affixing one pair of complementary plates to each tunnel on each side of the spinous process, and affixing a rod into troughs in plates on one side of the spinous process. | 10-03-2013 |
20140012384 | INTERBODY FUSION DEVICE AND ASSOCIATED METHODS - A method and apparatus is provided for use in spinal fusion procedures. An interbody fusion device has a first piece that is a load bearing device designed to bear the axial loading from the end plates of adjacent vertebrae. A second piece of the interbody fusion device is a retention component whose primary functions are to prevent migration of the load bearing device and loss or migration of graft material from within the load bearing device. A secondary function of the retention component is to address fixation of fasteners when the surgeon is confronted with a challenging access to adequate boney structures due to excessive curvature/angulation of the vertebrae column, minimal invasive surgery techniques, danger to surrounding vascular or neurological tissues, poor bone quality, or similar surgical complications. A tertiary function of the retention component is to provide better alignment and stabilization of misaligned vertebrae when spondylolisthesis is a significant factor. One or more fasteners secure the retention component to each of the vertebrae above and below the load bearing device. The fasteners cause the end plates of the vertebrae to compress the end plates to the load bearing device to facilitate proper fusion. | 01-09-2014 |
Patent application number | Description | Published |
20140378853 | Universal wearable limb band mounting, powering and providing an antenna for, diverse physiological sensors and monitors - A band, or bracelet, is semi-permanently attachable to, and wearable about, a limb of the human body. The limb band is in the physical form of a familiar, and well-accepted, flexible plastic hospital-type wrist bracelet. As well as providing a physical platform to attach, and to mount, any of a large number of diverse portable electronic physiological, motion and like sensors of the human body and its condition, the limb band houses, and electrically connects, any of (1) a battery that is preferably rechargeable, (2) a solar cell for recharging the battery, (3) an antenna, and/or (4) a universal electronic signal connector (such as a miniature USB connector port). In this manner the limb band economically serves as a universal platform for mounting, supplying power and/or abetting wireless and wired communication to and from, wearable electronic sensors and monitors of humans and animals. | 12-25-2014 |
Patent application number | Description | Published |
20130186770 | DEVICE AND METHOD OF OBTAINING DIOLS AND OTHER CHEMICALS USING DECARBOXYLATION - A method for converting carboxylic acids (including carboxylic acids derived from biomass) into hydrocarbons. The produced hydrocarbons will generally have at least two oxygen containing substituents (or other substituents). In one example of application, the electrolysis converts alkali salts of carboxylic acids into diols which can then be used as solvents or be dehydrated to produce dienes, which can then be used to produce elastic polymeric materials. This process allows custom synthesis of high value chemicals from renewable feed stocks such as carboxylic acids derived from biomass. | 07-25-2013 |
20130245347 | DEVICE AND METHOD FOR ARYL-ALKYL COUPLING USING DECARBOXYLATION - A method for alkylating aromatic compounds is described using an electrochemical decarboxylation process. This process produces aryl-alkyl compounds that have properties useful in Group V lubricants (and other products) from abundant and economical carboxylic acids. The process presented here is also advantageous as it is conducted at moderate temperatures and conditions, without the need of a catalyst. The electrochemical decarboxylation has only H | 09-19-2013 |
20130284607 | METHOD OF PRODUCING COUPLED RADICAL PRODUCTS - A method that produces coupled radical products from biomass. The method involves obtaining a lipid or carboxylic acid material from the biomass. This material may be a carboxylic acid, an ester of a carboxylic acid, a triglyceride of a carboxylic acid, or a metal salt of a carboxylic acid, or any other fatty acid derivative. This lipid material or carboxylic acid material is converted into an alkali metal salt. The alkali metal salt is then used in an anolyte as part of an electrolytic cell. The electrolytic cell may include an alkali ion conducting membrane (such as a NaSICON membrane). When the cell is operated, the alkali metal salt of the carboxylic acid decarboxylates and forms radicals. Such radicals are then bonded to other radicals, thereby producing a coupled radical product such as a hydrocarbon. The produced hydrocarbon may be, for example, saturated, unsaturated, branched, or unbranched, depending upon the starting material. | 10-31-2013 |
20140154766 | Method of Producing Coupled Radical Products from Biomass - A method that produces coupled radical products from biomass. The method involves obtaining a lipid or carboxylic acid material from the biomass. This material may be a carboxylic acid, an ester of a carboxylic acid, a triglyceride of a carboxylic acid, or a metal salt of a carboxylic acid, or any other fatty acid derivative. This lipid material or carboxylic acid material is converted into an alkali metal salt. The alkali metal salt is then used in an anolyte as part of an electrolytic cell. The electrolytic cell may include an alkali ion conducting membrane (such as a NaSICON membrane). When the cell is operated, the alkali metal salt of the carboxylic acid decarboxylates and forms radicals. Such radicals are then bonded to other radicals, thereby producing a coupled radical product such as a hydrocarbon. The produced hydrocarbon may be, for example, saturated, unsaturated, branched, or unbranched, depending upon the starting material. | 06-05-2014 |
20140251821 | CUSTOM IONIC LIQUID ELECTROLYTES FOR ELECTROLYTIC DECARBOXYLATION - Methods, equipment, and reagents for preparing organic compounds using custom electrolytes based on different ionic liquids in electrolytic decarboxylation reactions are disclosed. | 09-11-2014 |
20140331545 | Bio-Oil Upgrading Process - A method for upgrading pyrolysis oil into a hydrocarbon fuel involves obtaining a quantity of pyrolysis oil, separating the pyrolysis oil into an organic phase and an aqueous phase, and then upgrading the organic phase into a hydrocarbon fuel by reacting the organic phase with hydrogen gas using a catalyst. The catalyst used in the reaction includes a support material, an active metal and a zirconia promoter material. The support material may be alumina, silica gel, carbon, silicalite or a zeolite material. The active metal may be copper, iron, nickel or cobalt. The zirconia promoter material may be zirconia itself, zirconia doped with Y, zirconia doped with Sc and zirconia doped with Yb. | 11-13-2014 |
20140336418 | Production of Fuel from Chemicals Derived from Biomass - Hydrocarbons may be formed from six carbon sugars. This process involves obtaining a quantity of a hexose sugar. The hexose sugar may be derived from biomass. The hexose sugar is reacted to form an alkali metal levulinate, an alkali metal valerate, an alkali metal 5-hydroxy pentanoate, or an alkali metal 5-alkoxy pentanoate. An anolyte is then prepared for use in a electrolytic cell. The anolyte contains the alkali metal levulinate, the alkali metal valerate, the alkali metal 5-hydroxy pentanoate, or the alkali metal 5-alkoxy pentanoate. The anolyte is then decarboxylated. This decarboxylating operates to decarboxylate the alkali metal levulinate, the alkali metal valerate, the alkali metal 5-hydroxy pentanoate, or the alkali metal 5-alkoxy pentanoate to form radicals, wherein the radicals react to form a hydrocarbon fuel compound. | 11-13-2014 |
20140360866 | Production of Fuel from Chemicals Derived from Biomass - Hydrocarbons may be formed from six carbon sugars. This process involves obtaining a quantity of a hexose sugar. The hexose sugar may be derived from biomass. The hexose sugar is reacted to form an alkali metal levulinate, an alkali metal valerate, an alkali metal 5-hydroxy pentanoate, or an alkali metal 5-alkoxy pentanoate. An anolyte is then prepared for use in a electrolytic cell. The anolyte contains the alkali metal levulinate, the alkali metal valerate, the alkali metal 5-hydroxy pentanoate, or the alkali metal 5-alkoxy pentanoate. The anolyte is then decarboxylated. This decarboxylating operates to decarboxylate the alkali metal levulinate, the alkali metal valerate, the alkali metal 5-hydroxy pentanoate, or the alkali metal 5-alkoxy pentanoate to form radicals, wherein the radicals react to form a hydrocarbon fuel compound. | 12-11-2014 |
20150060296 | Hydrogen Utilization and Carbon Recovery - A method for upgrading bio-mass material is provided. The method involves electrolytic reduction of the material in an electrochemical cell having a ceramic, oxygen-ion conducting membrane, where the membrane includes an electrolyte. One or more oxygenated or partially-oxygenated compounds are reduced by applying an electrical potential to the electrochemical cell. A system for upgrading bio-mass material is also disclosed. | 03-05-2015 |
Patent application number | Description | Published |
20110024288 | DECARBOXYLATION CELL FOR PRODUCTION OF COUPLED RADICAL PRODUCTS - A method that produces coupled radical products from biomass. The method involves obtaining a lipid or carboxylic acid material from the biomass. This material may be a carboxylic acid, an ester of a carboxylic acid, a triglyceride of a carboxylic acid, or a metal salt of a carboxylic acid, or any other fatty acid derivative. This lipid material or carboxylic acid material is converted into an alkali metal salt. The alkali metal salt is then used in an anolyte as part of an electrolytic cell. The electrolytic cell may include an alkali ion conducting membrane (such as a NaSICON membrane). When the cell is operated, the alkali metal salt of the carboxylic acid decarboxylates and forms radicals. Such radicals are then bonded to other radicals, thereby producing a coupled radical product such as a hydrocarbon. The produced hydrocarbon may be, for example, saturated, unsaturated, branched, or unbranched, depending upon the starting material. | 02-03-2011 |
20110027848 | METHOD OF PRODUCING COUPLED RADICAL PRODUCTS FROM BIOMASS - A method that produces coupled radical products from biomass. The method involves obtaining a lipid or carboxylic acid material from the biomass. This material may be a carboxylic acid, an ester of a carboxylic acid, a triglyceride of a carboxylic acid, or a metal salt of a carboxylic acid, or any other fatty acid derivative. This lipid material or carboxylic acid material is converted into an alkali metal salt. The alkali metal salt is then used in an anolyte as part of an electrolytic cell. The electrolytic cell may include an alkali ion conducting membrane (such as a NaSICON membrane). When the cell is operated, the alkali metal salt of the carboxylic acid decarboxylates and forms radicals. Such radicals are then bonded to other radicals, thereby producing a coupled radical product such as a hydrocarbon. The produced hydrocarbon may be, for example, saturated, unsaturated, branched, or unbranched, depending upon the starting material. | 02-03-2011 |
20110168569 | METHOD OF PRODUCING COUPLED RADICAL PRODUCTS - A method that produces coupled radical products from biomass. The method involves obtaining a lipid or carboxylic acid material from the biomass. This material may be a carboxylic acid, an ester of a carboxylic acid, a triglyceride of a carboxylic acid, or a metal salt of a carboxylic acid, or any other fatty acid derivative. This lipid material or carboxylic acid material is converted into an alkali metal salt. The alkali metal salt is then used in an anolyte as part of an electrolytic cell. The electrolytic cell may include an alkali ion conducting membrane (such as a NaSICON membrane). When the cell is operated, the alkali metal salt of the carboxylic acid decarboxylates and forms radicals. Such radicals are then bonded to other radicals, thereby producing a coupled radical product such as a hydrocarbon. The produced hydrocarbon may be, for example, saturated, unsaturated, branched, or unbranched, depending upon the starting material. | 07-14-2011 |
20110226633 | ELECTROCHEMICAL SYNTHESIS OF ARYL-ALKYL SURFACANT PRECURSOR - An aryl-alkyl (R—Ar) hydrocarbon is prepared by an electrosynthesis process in an electrolytic cell having an alkali ion conductive membrane positioned between an anolyte compartment configured with an anode and a catholyte compartment configured with a cathode. An anolyte solution containing an alkali metal salt of an alkyl carboxylic acid and an aryl compound is introduced into the anolyte compartment. The aryl compound may include an alkali metal salt of an aryl carboxylic acid, an arene (aromatic) hydrocarbon, or an aryl alkali metal adduct (Ar | 09-22-2011 |
20120304530 | Bio-Oil Upgrading Process - A method for upgrading pyrolysis oil into a hydrocarbon fuel involves obtaining a quantity of pyrolysis oil, separating the pyrolysis oil into an organic phase and an aqueous phase, and then upgrading the organic phase into a hydrocarbon fuel by reacting the organic phase with hydrogen gas using a catalyst. The catalyst used in the reaction includes a support material, an active metal and a zirconia promoter material. The support material may be alumina, silica gel, carbon, silicalite or a zeolite material. The active metal may be copper, iron, nickel or cobalt. The zirconia promoter material may be zirconia itself, zirconia doped with Y, zirconia doped with Sc and zirconia doped with Yb. | 12-06-2012 |
20130001095 | METHOD OF PRODUCING COUPLED RADICAL PRODUCTS - A method that produces coupled radical products. The method involves obtaining a sodium salt of a carboxylic acid. The alkali metal salt is then used in an anolyte as part of an electrolytic cell. The electrolytic cell may include an alkali ion conducting membrane (such as a NaSICON membrane) that separates an anolyte compartment housing the anolyte from a catholyte compartment housing a catholyte. The anolyte includes a first solvent or mixture of solvents and a quantity of the sodium salt of the carboxylic acid. When the cell is operated, the alkali metal salt of the carboxylic acid decarboxylates and forms radicals. Such radicals are then bonded to other radicals, thereby producing a coupled radical product such as a hydrocarbon. | 01-03-2013 |
20140171688 | DECARBOXYLATION OF LEVULINIC ACID TO KETONE SOLVENTS - Ketones, specifically Methyl ethyl ketone (“MEK”) and octanedione, may be formed from six carbon sugars. This process involves obtaining a quantity of a six carbon sugar and then reacting the sugar to form levulinic acid and formic acid. The levulinic acid and formic acid are then converted to an alkali metal levulinate and an alkali metal formate (such as, for example, sodium levulinate and sodium formate.) The alkali metal levulinate is placed in an anolyte along with hydrogen gas that is used in an electrolytic cell. The alkali metal levulinate within the anolyte is decarboxylated to form MEK radicals, wherein the MEK radicals react with hydrogen gas to form MEK, or MEK radicals react with each other to form octanedione. The alkali metal formate may also be decarboxylated in the cell, thereby forming hydrogen radicals that react with the MEK radicals to form MEK. | 06-19-2014 |
Patent application number | Description | Published |
20090318407 | Inhibitors of protein kinases - The present invention is directed to compounds of formula I-II and pharmaceutically acceptable tautomers, salts, or stereoisomers thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma. | 12-24-2009 |
20100048567 | Inhibitors of syk and JAK protein kinases - The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma. | 02-25-2010 |
Patent application number | Description | Published |
20130029944 | INHIBITORS OF PROTEIN KINASES - The present invention is directed to compounds of formula I-II and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma. | 01-31-2013 |
20130165431 | INHIBITORS OF SYK AND JAK PROTEIN KINASES - The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma. | 06-27-2013 |
20140031361 | INHIBITORS OF PROTEIN KINASES - The present invention is directed to compounds of formula I-II and pharmaceutically acceptable tautomers, salts, or stereoisomers thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma. | 01-30-2014 |
20140371195 | INHIBITORS OF HISTONE DEMETHYLASES - The present application discloses compounds capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament. The compounds take the form | 12-18-2014 |
20140371214 | INHIBITORS OF HISTONE DEMETHYLASES - Compounds of the form | 12-18-2014 |
20150203453 | INHIBITORS OF HISTONE DEMETHYLASES - The present application discloses compounds capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament. The compounds take the form (I) | 07-23-2015 |
Patent application number | Description | Published |
20120063735 | Fiber Distribution Terminals - A fiber distribution terminal (FDT) includes a base plate, a spool, and an adapter for securing a connection between a fiber of an input fiber cable and a fiber of an output fiber cable, and an adapter plate. The spool is rotatably mounted to the base plate. The spool houses the input fiber cable. The adapter plate has a cable guide defining a channel for routing the output fiber cable from the adapter. The FDT can be mounted within a pre-installed enclosure or directly to a wall. | 03-15-2012 |
20130129295 | Fiber Optic Collector and Terminal Assemblies - A fiber optic collector and terminal assembly (CTA) can include a multi-fiber optic cable having a tail portion and first and second multi-fiber branches optically coupled to the tail portion. The first and second multi-fiber optic branches each have fewer fibers than the tail portion. The CTA also includes a plurality of single-fiber optic jumpers optically coupled to the first multi-fiber optic branch. Additionally, the CTA includes an adapter for securing a connection between a fiber of one of the plurality of single-fiber optic jumpers and a fiber of a single-fiber optic drop. | 05-23-2013 |
20130209052 | Adapter Retaining Systems - An adapter retaining system comprises an adapter, an adapter pack, and a retaining base. The retaining base allows the adapter pack to slide in a direction substantially parallel to a surface of the retaining base and prevents the adapter pack from moving in a direction substantially perpendicular to the surface. In another embodiment, an adapter retaining system comprises an adapter, an adapter pack, and an adapter plate. The adapter pack rotates about an axis substantially perpendicular to a surface of the adapter plate. In another embodiment, an adapter retaining system comprises an adapter, an adapter pack, and an adapter plate having a curved adapter post. The adapter pack slidably engages the adapter post. In another embodiment, an adapter retaining system comprises an adapter, and an adapter plate having a pair of adapter posts. The adapter posts directly receive the adapter. | 08-15-2013 |
20150093088 | Fiber Optic Terminal Assemblies - A fiber optic terminal assembly comprises a mounting plate configured to be mounted to a surface, a pivot bracket comprising a handle, and a spool rotatably mounted to the pivot bracket and configured to store a multi-fiber optic cable. The spool comprises an adapter for securing a connection between a fiber of the multi-fiber optic cable and a fiber of an output fiber cable. The spool and the pivot bracket are configured to be selectively coupled to the mounting plate. A method of using the fiber optic terminal assembly comprises paying out a multi-fiber optic cable stored on the spool by rotating the spool relative to the pivot bracket. The method also comprises selectively coupling the spool and the pivot bracket to a mounting plate after paying out the multi-fiber optic cable. Selectively coupling the spool and the pivot bracket substantially prevents rotation of the spool. | 04-02-2015 |