Lembo
Antonio Lembo, Savigliano IT
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20120197540 | MARKERS TO PREDICT SURVIVAL OF BREAST CANCER PATIENTS AND USES THEREOF - The present invention relates to a method to predict the mortality risk of a subject (p) affected of breast cancer comprising measuring the expression level of 105 specific genes in a biological sample, obtaining the prognostic score, S(p), that indicates the expression levels of said genes in said subject (p) affected of cancer, and predicting the mortality risk of said subject (p) affected of cancer. | 08-02-2012 |
David Lembo, Orbassano IT
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20120121623 | NOVEL ANTIPATHOGENIC PEPTIDES - The present invention relates to monomeric and multimeric peptidic compounds which have antipathogenic, in particular antiviral or/and antibacterial activity. In a preferred aspect, the peptide compounds of the invention have an activity in respect of a broad spectrum of viruses, both DNA and RNA viruses, irrespective of whether they possess virus envelope or not. Further, the present invention refers to compositions comprising said peptidic compounds for medical use, i.e. for the treatment or prevention of pathogenic, in particular viral or/and bacterial infections. | 05-17-2012 |
David Lembo, Torino IT
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20130130970 | LACTADHERIN-DERIVED PEPTIDES AS ANTIVIRAL AGENTS - The present invention relates to monomeric and multimeric peptidic compounds which have antiviral activity, particularly against integrin-using viruses, more particularly against rotavirus. Further, the present invention refers to compositions comprising said peptidic compounds for medical use or for use as food additives. | 05-23-2013 |
20130243721 | ANTI-VIRAL AGENTS AND COMPOSITIONS THEREOF - Guanidine-based poly (amidoamine) polymers of formula (I): wherein n is an integer between 3 and 400; R | 09-19-2013 |
Dawn Lembo, Leonia, NJ US
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20160058789 | CLOSTRIDIUM DIFFICILE SPORICIDAL COMPOSITIONS - Disclosed are sporicidal compositions, and methods of use thereof. The sporicidal compositions contain water, an organic solvent, and a spore-germinating agent containing an iodide source, a citrate source or both. The compositions have sporicidal activity against, e.g., | 03-03-2016 |
Giuseppe Lembo, Mugnano Del Cardinale (av) IT
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20120010386 | RECOMBINANT MELUSIN FUSION PROTEIN AS PHARMACOLOGICAL AGENT IN THE TREATMENT OF HEART PATHOLOGIES AND COMPOSITIONS THEREOF - A recombinant melusin fusion protein having an improved stability and a capability to reach intracellular compartments as compared to recombinant melusin in vivo, wherein said protein comprises i) a human melusin protein having the amino acid sequence as defined in SEQ ID No.:1, or a homologue thereof having at least 60%, preferably at least 80%, more preferably at least 90% sequence identity to SEQ ID No.:1 and having the function of native melusin protein or a human melusin portion derived from SEQ ID No.:1 or homologue thereof having at least 60%, preferably at least 80%, more preferably at least 90% sequence identity of the melusin portion derived from SEQ ID No.:1 and having the function of native melusin protein and ii) a cell penetrating polypeptide. | 01-12-2012 |
Giuseppe Lembo, Mugnano Del Cardinale IT
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20090036382 | TGF-Beta Modulators and Use Thereof - The present invention relates to molecules preferably of polypeptide nature with negative regulatory activity on the amount or activity of TGF-β through direct interaction with pro-TGF-β, and containing as active region a cysteine-rich polypeptide sequence defined as “EMI domain”, or its subfragments, wherein said “EMI domain” has at least 25% sequence homology to the ID NO2 sequence for pharmaceutical use. Even more preferably said polypeptide sequence consists of the EMI domain of the following proteins: emilin-1, emilin-2 and/or multimerin-2 or their subfragments having a length of at least 6 amino acids, capable of inhibiting the conversion of pro-TGFβ to mature TGFβ as anti-hypertensive drugs and polypeptides active on the cardiovascular system. The invention extends to the use of molecules which are known to negatively regulate TGF-β and to molecules which interfere with TGF-β binding to its receptors, or to inhibitors of TGF-β mRNA synthesis or TGF-β expression for the same therapeutic uses as anti-hypertensive drugs and polypeptides active on the cardiovascular system. | 02-05-2009 |
Graziano Lembo, Norfolk GB
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20110107544 | Air Rinse and Transport Apparatus - Air rinse and transport apparatus ( | 05-12-2011 |
Kristin Lembo, Hudson, MA US
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20140042236 | Sprinkler Assembly System - A sprinkler system having a sprinkler assembly with at least one sprinkler head having a removable top coupled thereto by an attachment means. A female inlet removably couples the sprinkler head to a swing joint, which is buried below the sprinkler head and connects the sprinkler head to the irrigation feed. The removable top has a plurality of openings for exporting water from the irrigation feed outwardly therefrom. A top surface of the sprinkler head includes crushed stone for stabilizing the sprinkler assembly. The sprinkler system further includes a control system in electronic communication with a valve and control box connected to the sprinkler assembly. | 02-13-2014 |
Michael Lembo, Souderton, PA US
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20150337528 | SYSTEM, METHOD AND APPARATUS FOR ATTIC RAFTER EXTENSION FOR STORAGE - A support structure may have a base having surfaces including a top, a bottom, a front, a rear and sides. A first top slot may be formed in the top and may extend at least partially between the front and the rear. A second top slot may be formed in the top and may extend at least partially between the sides. In addition, a bottom slot may be formed in the bottom. A system for attic storage can include an attic having attic joists. A plurality of support structures, each comprising a base, may be mounted to the attic joists. At least two conventional lumber studs may be included and may extend between adjacent ones of the bases. In addition, a plurality of lumber panels may be mounted to at least one of the bases and the lumber studs. | 11-26-2015 |
Michael J. Lembo, Souderton, PA US
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20090266025 | INSULATION BOARD WITH AIR/RAIN BARRIER COVERING AND WATER-REPELLENT COVERING - A previously formed unitary building exterior envelope product is provided, comprising: a mineral fiber insulation board including a binder having a hydrophobic agent and is resistant to liquid water-penetration and has first and second major surfaces, an exterior facing material, which resists air infiltration and liquid water penetration, laminated to the first major surface, the exterior facing material being permeable to water vapor, and a continuous interior facing laminated to the second major surface, so that the second major surface is resistant to liquid water-penetration and is permeable to water vapor. The section of product is mounted to an exterior side of a plurality of framing members of an exterior wall of a building, so that the interior facing faces the framing members. An exterior layer is mounted to the framing members using a connection device that passes through the section of product, with the facing material facing the exterior layer. | 10-29-2009 |
20100088998 | SEGMENTED BAND JOIST BATTS AND METHOD OF MANUFACTURE - Insulation is partially divided into segments ( | 04-15-2010 |
20100107535 | Segmented Band Joist Batts and Method of Manufacture - Insulation is partially divided into segments ( | 05-06-2010 |
20110183096 | Foamed Airstream Surface Duct Product - The present invention provides insulation duct products including an insulation layer containing fibrous material bound with a resinous binder, an inner surface and an outer surface, and a closed cell foam layer adhered to an inner surface of the insulation layer. The closed cell foam layer includes a thickness of less than 0.5 inches (1.27 cm), and has a density of less than about 12 pcf. | 07-28-2011 |
Nicholas J. Lembo, Atlanta, GA US
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20090112207 | SKELETAL MANIPULATION METHOD - A method of treating scoliosis in a subject includes securing a scoliosis treatment device to first and second locations on the subject's skeletal system, the scoliosis treatment device including a first portion, a second portion moveably mounted relative to the first portion, and an adjustment device disposed on the device and configured to change a distraction force between the first location and the second location, the adjustment device including a rotationally mounted magnetic element configured to move the second portion relative to the first portion in response to rotation of the magnetic element. An external adjustment device is provided external to the subject and is able to adjust the distraction force between the first location and second location. | 04-30-2009 |
20120157996 | SKELETAL MANIPULATION METHOD - A method of treating scoliosis in a subject includes securing a scoliosis treatment device to first and second locations on the subject's skeletal system, the scoliosis treatment device including a first portion, a second portion moveably mounted relative to the first portion, and an adjustment device disposed on the device and configured to change a distraction force between the first location and the second location, the adjustment device including a rotationally mounted magnetic element configured to move the second portion relative to the first portion in response to rotation of the magnetic element. An external adjustment device is provided external to the subject and is able to adjust the distraction force between the first location and second location. | 06-21-2012 |
20130296859 | SKELETAL MANIPULATION METHOD - A method of treating scoliosis in a subject includes securing a scoliosis treatment device to first and second locations on the subject's skeletal system, the scoliosis treatment device including a first portion, a second portion moveably mounted relative to the first portion, and an adjustment device disposed on the device and configured to change a distraction force between the first location and the second location, the adjustment device including a rotationally mounted magnetic element configured to move the second portion relative to the first portion in response to rotation of the magnetic element. An external adjustment device is provided external to the subject and is able to adjust the distraction force between the first location and second location. | 11-07-2013 |