Patent application number | Description | Published |
20090179355 | METHODS FOR MULTI-MATERIAL STEREOLITHOGRAPHY - Methods and systems of stereolithography for building cost-efficient and time-saving multi-material, multi-functional and multi-colored prototypes, models and devices configured for intermediate washing and curing/drying is disclosed including: laser(s), liquid and/or platform level sensing system(s), controllable optical system(s), moveable platform(s), elevator platform(s), recoating system(s) and at least one polymer retaining receptacle. Multiple polymer retaining receptacles may be arranged in a moveable apparatus, wherein each receptacle is adapted to actively/passively maintain a uniform, desired level of polymer by including a recoating device and a material fill/remove system. The platform is movably accessible to the polymer retaining receptacle(s), elevator mechanism(s) and washing and curing/drying area(s) which may be housed in a shielded enclosure(s). The elevator mechanism is configured to vertically traverse and rotate the platform, thus providing angled building, washing and curing/drying capabilities. A horizontal traversing mechanism may be included to facilitate manufacturing between components of SL cabinet(s) and/or alternative manufacturing technologies. | 07-16-2009 |
20110059292 | HYDROGEL CONSTRUCTS USING STEREOLITHOGRAPHY - A preferred embodiment of the present invention provides a method and system for building cost-efficient biocompatible hydrogel constructs using stereolithography. Hydrogel constructs may be used in, for example, multi-lumen nerve regeneration conduits and other tissue engineering scaffolds with embedded channel architecture that facilitate tissue regeneration through possible incorporation of precisely located bioactive agents, cells, and other desired inert and/or active chemical agents and devices. Another preferred embodiment of the present invention provides a method of fabricating a hydrogel construct comprising: solidifying a first solution into a first construct layer with a first energy dosage using stereolithography, the first solution comprising: a first polymer; and a first photoinitiator, wherein the first polymer and first photoinitiator are of a first concentration. | 03-10-2011 |
Patent application number | Description | Published |
20090105799 | RENAL ASSESSMENT SYSTEMS AND METHODS - Techniques for assessing a physiological profile of a patient include advancing a catheter shaft of a bifurcated renal catheter system into an aorta of the patient, deploying branches of the bifurcated renal catheter system into the renal arteries of the patient, detecting a renal arterial physiological parameter with a sensing mechanism, and assessing the physiological profile of the patient based on the physiological parameter. Related techniques include modifying or initiating pharmacological or surgical treatments for the patient based on the assessment. | 04-23-2009 |
20090306704 | SPIRAL SHAPED FILTER - In one embodiment of the present invention there is provided a filter having a first spiral support member having a first end and a second end, a second spiral support member positioned adjacent the first spiral support member to form an open loop between the first end and the second end of the first spiral support member; and a filtering structure attached to the open loop. In another embodiment of the present invention there is provided a filter having a first spiral support member having a first end and a second end; a second spiral support member positioned adjacent the first spiral support member to form a loop between the first end and the second end; a material covering a portion of the first and the second spiral support members; and a structure attached to the loop. | 12-10-2009 |
20100324590 | METHODS FOR MAINTAINING A FILTERING DEVICE WITHIN A LUMEN - In one embodiment of the present invention there is provided a method of filtering blood flow in a lumen by positioning an open loop filter support structure within a lumen; maintaining a position of the open loop filter support structure within the lumen using radial force generated by the open loop filter support structure; and filtering blood flow in the lumen using a filter supported by the open loop filter support structure. In one aspect, there is also applying radial force generated by the open loop filter support structure along the axial dimension of the lumen. In another embodiment of the present invention there is provided a method of providing a filter across a lumen flow path by providing a filter support structure having a first end, a crossover section, and a second end; and fixing the position of the filter support structure within the lumen by positioning the first end against a first portion of the lumen and positioning the second end against a second portion of the lumen; and using the filter support structure to provide a filter across the lumen flow path. In one aspect, the ends do not pierce the lumen surface. | 12-23-2010 |
20120179196 | DISTAL PROTECTION DEVICES AND METHODS OF PROVIDING DISTAL PROTECTION - A filter and methods of use to provide distal protection during a vascular procedure is provided. The filter includes a first spiral shaped support member joined to a second spiral support member to form a crossover and to form a first generally planar support frame and a second generally planar support frame. A tether is on one of the first end or the second end and a capture structure is attached to the first support frame or the second support frame. The capture structure extends in a non-planar fashion relative to the generally planar first or second support frame to which the capture structure is attached. After use to capture debris, the filter is recovered in a manner to close while maintaining captured debris within the filter. | 07-12-2012 |
20130012981 | ENDOLUMINAL FILTER WITH FIXATION - An endoluminal filter including a first support member and a second support member attached to the first support member to form a crossover. A material capture structure extends between the first and second support members, the crossover and the first end or the second end of the first support member. The filter includes at least one tissue anchor on the first support member and the second support member. There is a method of positioning a filter within a lumen including advancing a sheath containing a filter through the lumen. Next, deploying a retrieval feature against the lumen wall while maintaining substantially all of a material capture structure of the filter within the sheath. Next, deploying the material capture structure of the filter from the sheath to a position across the lumen along with engaging the lumen wall with fixation elements positioned along the filter. | 01-10-2013 |
20130035715 | DEVICES AND METHODS FOR VESSEL OCCLUSION - Embodiments of devices and methods for vessel occlusion include an endoluminal occlusion device having a support structure forming at least two open loops with a crossover point between adjacent loops and free movement of the support structure at the crossover between adjacent loops, wherein the support structure is configured to extend along the walls of a lumen; and a first occlusive material attached to and across one of the at least two loops formed by the support structure, wherein the occlusive material is configured to occlude the flow of fluid within the lumen. | 02-07-2013 |
20130184744 | SPIRAL SHAPED FILTER - In one embodiment, a filter includes a first spiral support member having a first end and a second end; a second spiral support member positioned adjacent the first spiral support member to form a loop between the first end and the second end; a material covering a portion of the first and the second spiral support members; and a structure attached to the loop. | 07-18-2013 |
20130190804 | METHODS FOR PROVIDING PROTECTION DURING PROCEDURES IN THE VASCULATURE - In one embodiment of the present invention there is provided a method of providing protection during a procedure performed in the vasculature using an open loop filter device comprising two elongate support members positioned to form at least one crossover location between adjacent open loops of the device. The method may also include placing the open loop device down stream of a location in the vasculature performing a procedure to treat the vasculature in proximity to the location; and capturing debris released during the procedure in a material capture structure suspended between the elongate support members and across the vessel. Additionally, there can be a step of maintaining the open loop filter device downstream of the location along the wall of the vasculature while permitting movement along the wall of the vasculature of the two elongate support members adjacent the material capture structure. | 07-25-2013 |
20130231696 | COATED ENDOLUMINAL FILTERS - There are described a number of different coated endoluminal filters. The filters include a support structure formed from two shape memory metal wires joined at a first end and a second end. There is a first loop formed by the two wires and positioned directly adjacent to the first end. There is a second loop formed by the two wires and positioned directly adjacent to the second end. A filtering structure is formed from a suture material and positioned across the two metal wires so as to be within one of the two loops. There is a coating over at least a portion of the wires forming one of the two loops of the support structure containing the filtering structure. In one aspect, the coating is used to secure the filtering structure to the at least one of the two loops of the support structure. | 09-05-2013 |
20130267991 | DISTAL PROTECTION DEVICE - There is described an endoluminal filter having an end cap having a lumen sized to receive there through a guidewire used in the positioning of the filter within the vasculature. There is a first support member with a pre-formed counter clockwise spiral shape and a second support member with a pre-formed clockwise spiral shape positioned adjacent to one another to form a proximal support frame, a distal support frame with a crossover between the proximal support frame and the distal support frame with a proximal portion of the first and the second spiral support members being attached to the end cap. A material capture structure having a rim and an apex with the rim attached to the proximal support frame and the apex extending distally through without attaching to the distal support frame. | 10-10-2013 |
20130282043 | METHODS FOR MAINTAINING A FILTERING DEVICE WITHIN A LUMEN - In one embodiment of the present invention there is provided a method of filtering blood flow in a lumen by positioning an open loop filter support structure within a lumen; maintaining a position of the open loop filter support structure within the lumen using radial force generated by the open loop filter support structure; and filtering blood flow in the lumen using a filter supported by the open loop filter support structure. In one aspect, there is also applying radial force generated by the open loop filter support structure along the axial dimension of the lumen. In another embodiment of the present invention there is provided a method of providing a filter across a lumen flow path by providing a filter support structure having a first end, a crossover section, and a second end; and fixing the position of the filter support structure within the lumen by positioning the first end against a first portion of the lumen and positioning the second end against a second portion of the lumen; and using the filter support structure to provide a filter across the lumen flow path. In one aspect, the ends do not pierce the lumen surface. | 10-24-2013 |
20130282044 | BIODEGRADABLE IMPLANTABLE DEVICE - In one embodiment of the present invention there is provided a biodegradable implantable device. The biodegradable implant device can include one or more elongate spiral support structures that can be biodegradable. Some embodiments can further include a material capture structure that can be biodegradable. A pharmacological agent can also be incorporated into the elongate spiral support structures and/or the material capture structure. | 10-24-2013 |
20130282045 | ENDOLUMINAL FILTER - In one embodiment of the present invention there is provided an implantable filter. The filter can include a first support member having a first end and a second end; a second support member positioned adjacent the first support member to form an open loop between the first end and the second end of the first support member; a wrapping material wrapped around a portion of the first support member and a portion of the second support member that forms the open loop; and a filtering structure attached to the open loop by the wrapping material. | 10-24-2013 |
20130289519 | METHODS FOR MAINTAINING A FILTERING DEVICE WITHIN A LUMEN - In one embodiment of the present invention there is provided a method of filtering blood flow in a lumen by positioning an open loop filter support structure within a lumen; maintaining a position of the open loop filter support structure within the lumen using radial force generated by the open loop filter support structure; and filtering blood flow in the lumen using a filter supported by the open loop filter support structure. In one aspect, there is also applying radial force generated by the open loop filter support structure along the axial dimension of the lumen. | 10-31-2013 |
20130289609 | ENDOLUMINAL FILTER - In one embodiment of the present invention there is provided an implantable filter. The implantable filter can include a first support member having a first end and a second end; a second support member positioned adjacent the first support member to form a loop between the first end and the second end of the first support member; and a filtering structure attached to the loop by a plurality of segmented tubes. | 10-31-2013 |
20130289610 | FILTER DELIVERY METHODS - In one embodiment of the present invention there is provided a method of positioning within a lumen a filtering device having a filter and a filter support structure by advancing the filtering device along the lumen while the filter and the filter support structure are in a stowed configuration; releasing the filter and the filter support structure from the stowed configuration so that opposing spiral elements of the filter support structure are in atraumatic contact with the lumen and the filter is positioned across the lumen flow path. | 10-31-2013 |
20130289611 | RETRIEVABLE ENDOLUMINAL FILTER - In one embodiment of the present invention there is provided a filter having a first support member having a first end and a second end; a second support member joined to the first support member at the first end and positioned adjacent the first support member to form a support frame; a material capture structure within the support frame; and a retrieval feature on the first end and on the second end. In one aspect, the first support member or the second support member has a spiral shape. | 10-31-2013 |
20130296918 | ENDOLUMINAL FILTER - In one embodiment of the present invention there is provided a filter having a first elongate member having a first section and a second section; a second elongate member having a first section and a second section; a first rounded frame formed by the first sections; a second rounded frame formed by the second sections; and a material removal structure supported by the first rounded frame. In another embodiment of the present invention there is provided a filter, having a first elongate member having a first spiral section and a second spiral section; a second elongate member having a first spiral section and a second spiral section; and a material capture structure extending between the first spiral sections. | 11-07-2013 |
Patent application number | Description | Published |
20080221551 | ACUTE KIDNEY INJURY TREATMENT SYSTEMS AND METHODS - Systems and methods for the clinical treatment of individuals susceptible to or suffering from acute kidney injury are provided. Drugs, biologics, or other therapies or treatments are administered by fluid agent delivery directly to the kidneys via their arterial blood supply. Bifurcated renal artery infusion catheter devices and methods can treat kidney injury in patients with locally-delivered drugs, biologics, and other agents, so as to increase the ability of the kidneys to excrete nitrogenous waste products from the blood, and prevent or ameliorate azotemia. | 09-11-2008 |
20090305990 | BI-LATERAL LOCAL RENAL DELIVERY FOR TREATING CONGESTIVE HEART FAILURE AND FOR BNP THERAPY - The invention relates to systems and methods for local renal delivery of agents to subjects that are at risk for congestive heart failure and other conditions. The invention encompasses devices for renal drug delivery and method of use. | 12-10-2009 |
20090306625 | TREATMENT SYSTEMS AND METHODS FOR RENAL-RELATED DISEASES - Systems and methods are provided for locally delivering specific prophylactic, regenerative, or therapeutic agents within the body of a patient. Systems and methods can involve direct delivery of prophylactic, regenerative, or therapeutic agents into branch blood vessels or body lumens from a main vessel or lumen, respectively, and in particular into renal arteries extending from an aorta in a patient. Drug infusion techniques encompass specific treatment and prevention regimes for renal diseases including, but not limited to, Acute Kidney Injury, Renal Cell Carcinoma, Polycystic Kidney Disease, and Chronic Kidney Disease. | 12-10-2009 |
20090318857 | SHEATH FOR USE IN PERIPHERAL INTERVENTIONS - A dual lumen introducer sheath provides access to at least one renal artery and at least one peripheral blood vessel of a patient. The introducer sheath includes a proximal hub comprising first and second ports, a first lumen, and a second lumen. The first lumen extends from the first port to a first distal aperture and has sufficient length such that when the first port is positioned outside the patient the first distal aperture is positionable in the abdominal aorta at or near origins of the patient's renal arteries. The second lumen extends from the second port to a second distal aperture, has a shorter length than the length of the first lumen, and is configured to allow passage of a catheter device through the second lumen and into or through an iliac artery contralateral to an insertion point of the introducer sheath into the patient. | 12-24-2009 |
Patent application number | Description | Published |
20090171334 | SUBDERMAL CRYOGENIC REMODELING OF MUSCLES, NERVES, CONNECTIVE TISSUE, AND/OR ADIPOSE TISSUE (FAT) - Devices, systems, and methods treat cosmetic defects, and often apply cooling with at least one tissue-penetrating probe inserted through of the skin of a patient. The cooling may remodel one or more target tissue so as to effect a desired change in a composition of the target tissue and/or a change in its behavior. Exemplary embodiments of the cooling treatments will interfere with the nerve/muscle contractile function chain so as to mitigate wrinkles of the skin. Related treatments may be used therapeutically for treatment of back and other muscle spasms, chronic pain, and the like. Some embodiments may remodel subcutaneous adipose tissue so as to alter a shape or appearance of the skin surface. | 07-02-2009 |
20090248001 | Pain management using cryogenic remodeling - Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated. | 10-01-2009 |
20100198207 | SUBDERMAL CRYOGENIC REMODELING OF MUSCLES, NERVES, CONNECTIVE TISSUE, AND/OR ADIPOSE TISSUE (FAT) - Devices, systems, and methods treat cosmetic defects, and often apply cooling with at least one tissue-penetrating probe inserted through of the skin of a patient. The cooling may remodel one or more target tissue so as to effect a desired change in a composition of the target tissue and/or a change in its behavior. Exemplary embodiments of the cooling treatments will interfere with the nerve/muscle contractile function chain so as to mitigate wrinkles of the skin. Related treatments may be used therapeutically for treatment of back and other muscle spasms, chronic pain, and the like. Some embodiments may remodel subcutaneous adipose tissue so as to alter a shape or appearance of the skin surface. | 08-05-2010 |
20110144631 | SUBDERMAL CRYOGENIC REMODELING OF MUSCLES, NERVES, CONNECTIVE TISSUE, AND/OR ADIPOSE TISSUE (FAT) - Devices, systems, and methods treat cosmetic defects, and often apply cooling with at least one tissue-penetrating probe inserted through of the skin of a patient. The cooling may remodel one or more target tissue so as to effect a desired change in a composition of the target tissue and/or a change in its behavior. Exemplary embodiments of the cooling treatments will interfere with the nerve/muscle contractile function chain so as to mitigate wrinkles of the skin. Related treatments may be used therapeutically for treatment of back and other muscle spasms, chronic pain, and the like. Some embodiments may remodel subcutaneous adipose tissue so as to alter a shape or appearance of the skin surface. | 06-16-2011 |
20120065629 | SUBDERMAL CRYOGENIC REMODELING OF MUSCLES, NERVES, CONNECTIVE TISSUE, AND/OR ADIPOSE TISSUE (FAT) - Devices, systems, and methods treat cosmetic defects, and often apply cooling with at least one tissue-penetrating probe inserted through of the skin of a patient. The cooling may remodel one or more target tissue so as to effect a desired change in a composition of the target tissue and/or a change in its behavior. Exemplary embodiments of the cooling treatments will interfere with the nerve/muscle contractile function chain so as to mitigate wrinkles of the skin. Related treatments may be used therapeutically for treatment of back and other muscle spasms, chronic pain, and the like. Some embodiments may remodel subcutaneous adipose tissue so as to alter a shape or appearance of the skin surface. | 03-15-2012 |
20130218148 | Pain Management Using Cryogenic Remodeling - Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated. | 08-22-2013 |
20130315924 | Subdermal Tissue Remodeling Using Myostatin, Methods and Related Systems - Systems and methods of tissue remodeling or altering a surface of a skin of a patient are provided. A method includes increasing myostatin activity in a target tissue. Methods can include increasing myostatin activity in a target tissue in addition to various tissue remodeling techniques, including cryogenic cooling of target tissue for tissue remodeling. | 11-28-2013 |
20130324990 | Replaceable and/or Easily Removable Needle Systems for Dermal and Transdermal Cryogenic Remodeling - The present invention generally provides improved medical devices, systems, and methods. Some embodiments of the present invention apply cooling with at least one small, tissue-penetrating probe, the probe often comprising a needle having a size suitable for inserting through an exposed surface of the skin of a patient without leaving a visible scar. The cooling may remodel one or more target tissue so as to effect a desired change in a composition of the target tissue and/or a change in its behavior. Exemplary embodiments make use of replaceable needle probes supported by a probe body handle, with small needle probes often being replaced during treatment of a single patient. Careful control over the control of cryogenic cooling fluid into a needle probe can allow the length of the active cooling to be controlled through depletion of liquid from an evaporating cryogenic cooling flow. | 12-05-2013 |
20140249519 | PAIN MANAGEMENT USING CRYOGENIC REMODELING - Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated. | 09-04-2014 |