Patent application number | Description | Published |
20090105201 | Pulmonary Pharmaceutical Formulations - The present invention provides improved pharmaceutical formulations for pulmonary delivery having improved chemical and physical stability of the therapeutic, prophylactic or diagnostic agent as compared to formulations known in the art. The improved pharmaceutical formulations of the invention for administration to the respiratory system of a patient for the treatment of a variety of disease conditions comprise a mass of biocompatible particles comprising an active agent, and a hydrogenated starch hydrosylate (HSH). The improvement over the prior art comprises the presence of HSH in the pharmaceutical formulation. The invention further relates to a method of treating diseases comprising administering the pharmaceutical formulations of the present invention to the respiratory system of a patient in need of treatment. | 04-23-2009 |
20100272811 | COMPLEX OF TROSPIUM AND PHARMACEUTICAL COMPOSITIONS THEREOF - The invention is directed to a complex of trospium and saccharin. In one embodiment, the complex is a crystalline form. In another embodiment, the complex is a monohydrate form. The invention also encompasses methods of preparing the the saccharin complex of trospium and to pharmaceutical compositions thereof. | 10-28-2010 |
20130172268 | DRUG DELIVERY THROUGH HYDROGEL PLUGS - An embodiment is a medical prosthesis for blocking or reducing tear flow through a punctum or canaliculus of a human eye and delivering a drug to the eye that comprises a dehydrated covalently crosslinked synthetic hydrophilic polymer hydrogel with dimensions to pass through a puncta lacrimali, with the dehydrated hydrogel absorbing physiological water to swell to at least 1 mm in cross-sectional width and conformably fit a canaliculus, with the hydrogel comprising a therapeutic agent dispersed through the hydrogel for release to an eye, with the hydrogel having a water content of at least about 50% by weight or volume when allowed to fully hydrate in vitro in physiological saline. | 07-04-2013 |
20140148424 | Pulmonary Pharmaceutical Formulations - The present invention provides improved pharmaceutical formulations for pulmonary delivery having improved chemical and physical stability of the therapeutic, prophylactic or diagnostic agent as compared to formulations known in the art. The improved pharmaceutical formulations of the invention for administration to the respiratory system of a patient for the treatment of a variety of disease conditions comprise a mass of biocompatible particles comprising an active agent, and a hydrogenated starch hydrosylate (HSH). The improvement over the prior art comprises the presence of HSH in the pharmaceutical formulation. The invention further relates to a method of treating diseases comprising administering the pharmaceutical formulations of the present invention to the respiratory system of a patient in need of treatment. | 05-29-2014 |
Patent application number | Description | Published |
20110159289 | Method of encapsulating particulate materials - A method of encapsulating particulate materials that enables the particulate materials to be used in end use applications where they currently are not useful. The method uses specific sol gel technology to encapsulate solid particles. In addition, the method can be used to multiple coat a coated particle. | 06-30-2011 |
20110177991 | Cleaner and polish formulation - A novel cleaner and polish formulation that is eco friendly, that is, it is formulated without alcohols, organic solvents and without normal cleaning and polishing components, for example, amine functional materials, that are undesirable with regard to the environment. | 07-21-2011 |
20130230676 | Two- and Three-Component Siloxanes and Related Compounds and Compositions - Compositions are disclosed that comprise at least one compound of formula IV: | 09-05-2013 |
20140086857 | Compositions Comprising Siloxane Polymer - Compositions comprising siloxane polymers are disclosed. The compositions are useful as thixotropic bases for a variety of components, such as antimicrobial agents, sterilants, medicaments, antibiotics, analgesics, essential oils, preservatives, colorants, fragrances, and the like. Methods for preparing the compositions are also disclosed. | 03-27-2014 |
20140255322 | SILOXANE POLYMER AND ACTIVES - A siloxane polymer base that is useful as an excipient for many variable materials that can be compounded into it. Also disclosed are a method for the preparation of such bases, and another method regarding the preparation of the base and actives. | 09-11-2014 |
20150051130 | HEAT PUMP ADDITIVE PROVIDING ENHANCED EFFICIENCY - Improvements in the efficiency of heat pump systems including refrigeration units, heating and air conditioning systems and the like using a composition that is a pump oil comprising at least a compressor oil and, a material selected from the group consisting of an organic phosphate and mixtures of organic phosphates and, a hydxotreated heavy naphthenic distillate. | 02-19-2015 |
Patent application number | Description | Published |
20100319632 | PRESSURE-APPLYING GARMENT FOR ANIMALS - A garment to reduce an animal's anxiety, fearfulness, overexcitement, or a combination thereof. The garment may include a central portion, flaps extending from opposite sides of the central portion, and, in some cases, a cinching member that extends from a central area of the central portion. The flaps may be fastened together around the chest and stomach of the animal, and the cinching member may be fastened to the central portion or one or more flaps to tighten the garment further, applying pressure to reduce anxiety, fearfulness, or over-excitement. Straps may be provided to secure the garment to the animal's neck. One material that may be used in making the garment is a fabric made of 55% cotton, 35% polyester, and 10% spandex. The animal may generally be any animal with four legs, for example, a dog or cat, or two arms and two legs, for example, a monkey. | 12-23-2010 |
20130042820 | PRESSURE-APPLYING GARMENT FOR ANIMALS - A garment to reduce an animal's anxiety, fearfulness, overexcitement, or a combination thereof. The garment may include a central portion, flaps extending from opposite sides of the central portion, and, in some cases, a cinching member that extends from a central area of the central portion. The flaps may be fastened together around the chest and stomach of the animal, and the cinching member may be fastened to the central portion or one or more flaps to tighten the garment further, applying pressure to reduce anxiety, fearfulness, or over-excitement. Straps may be provided to secure the garment to the animal's neck. One material that may be used in making the garment is a fabric made of 55% cotton, 35% polyester, and 10% spandex. The animal may generally be any animal with four legs, for example, a dog or cat, or two arms and two legs, for example, a monkey. | 02-21-2013 |
20130186348 | PRESSURE-APPLYING ANIMAL GARMENT - A garment to reduce an animal's anxiety, fearfulness, overexcitement, or a combination thereof. The garment may include a central portion and first, second, and third flaps. The first and second flaps extend from opposite sides of the central portion and the third flap extends from a central, inner surface area of the central portion. The inner surface is configured to be proximate to the animal's body. The flaps are configured to extend around the animal's mid-body such that the central portion and flaps form a shape conforming to the outside of the animal's mid-body. The third flap may be between the central portion, the second flap, or a combination thereof and the animal's body. The garment may apply pressure to the animal adequate to reduce anxiety, fearfulness, overexcitement, or a combination thereof in the animal. | 07-25-2013 |
20130247840 | PRESSURE-APPLYING GARMENT FOR ANIMALS - A garment to reduce an animal's anxiety, fearfulness, overexcitement, or a combination thereof. The garment may include a central portion, flaps extending from opposite sides of the central portion, and, in some cases, a cinching member that extends from a central area of the central portion. The flaps may be fastened together around the chest and stomach of the animal, and the cinching member may be fastened to the central portion or one or more flaps to tighten the garment further, applying pressure to reduce anxiety, fearfulness, or over-excitement. Straps may be provided to secure the garment to the animal's neck. One material that may be used in making the garment is a fabric made of 55% cotton, 35% polyester, and 10% spandex. The animal may generally be any animal with four legs, for example, a dog or cat, or two arms and two legs, for example, a monkey. | 09-26-2013 |
20140116355 | CONVERTIBLE LEASH AND HARNESS SYSTEM AND METHOD - A restraining apparatus for an animal including a combination of a leash and a harness to be used in conjunction with a collar. The restraining apparatus includes a ring defining an opening. A coupling element for fastening to a collar on the animal is mounted to the ring. A substantially rigid arm is mounted to the ring and extends to a free distal end spaced from the ring, with the arm forming a substantially elongated opening with the ring. A leash may be attached to the ring. When the restraining apparatus is applied to the animal as a harness, the coupling element is fastened to the collar, and the leash is wrapped around the torso of the animal, engages the arm at the elongated opening, and may freely slide and tighten around the torso of the animal. | 05-01-2014 |
20150083054 | PRESSURE-APPLYING GARMENT FOR ANIMALS - A garment to reduce an animal's anxiety, fearfulness, overexcitement, or a combination thereof. The garment may include a central portion, flaps extending from opposite sides of the central portion, and, in some cases, a cinching member that extends from a central area of the central portion. The flaps may be fastened together around the chest and stomach of the animal, and the cinching member may be fastened to the central portion or one or more flaps to tighten the garment further, applying pressure to reduce anxiety, fearfulness, or over-excitement. Straps may be provided to secure the garment to the animal's neck. One material that may be used in making the garment is a fabric made of 55% cotton, 35% polyester, and 10% spandex. The animal may generally be any animal with four legs, for example, a dog or cat, or two arms and two legs, for example, a monkey. | 03-26-2015 |
Patent application number | Description | Published |
20090012061 | A Method of Treating Cancer - The present invention relates to a method of treating cellular proliferative diseases, in particular cancer, which comprises administering a modulator of the activity of the mitotic kinesin KSP, wherein the activity of the KSP modulator is dependent on the presence of microtubules. It is believed that the KSP modulators utilized in the instant method bind to the KSP protein in a previously unreported manner, since the compounds do not bind competitively with respect to either microtubules or ATP, the substrates of KSP. The modulators useful in the instant methods are furthermore not active against the non-microtubule stimulated activity of KSP. Cellular proliferative diseases that may be treated using the method disclosed herein are, for example cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and inflammation. | 01-08-2009 |
20100009957 | NOVEL INHIBITORS OF BETA-LACTAMASE - A class of 7-oxo-2,6-diazabicyclo-[3.2.0]-heptane-6-sulfonic acid compounds substituted at the two position of the bicyclic ring with a heterocyclylaminocarbonyl group or a carbocyclylaminocarbonyl group are β-lactamase inhibitors. The compounds and their prodrugs and pharmaceutically acceptable salts are useful in the treatment of bacterial infections in combination with β-lactam antibiotics. In particular, the compounds are suitable for use with β-lactam antibiotics (e.g., imipenem and ceftazidime) against micro-organisms resistant to β-lactam antibiotics due to the presence of the β-lactamases. | 01-14-2010 |
20110294777 | BETA-LACTAMASE INHIBITORS - Substituted bicyclic beta-lactams of Formula I: (I), are β-lactamase inhibitors, wherein a, X, R | 12-01-2011 |
20140045746 | ANTIDIABETIC TRICYCLIC COMPOUNDS - Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia. | 02-13-2014 |
20140309213 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL - This invention relates to compounds of Formula I-VI having the following general structure: | 10-16-2014 |
20150025046 | PREPARATION AND USE OF BICYCLIC HIMBACINE DERIVATIVES AS PAR-1 RECEPTOR ANTAGONISTS - The present invention relates to bicyclic himbacine derivatives of the formula or a pharmaceutically acceptable salt thereof, wherein: X is —O—, —N(R), —C(R | 01-22-2015 |