Patent application number | Description | Published |
20090105143 | HIV FUSION INHIBITOR PEPTIDES WITH IMPROVED BIOLOGICAL PROPERTIES - Provided is an HIV fusion inhibitor peptide having an amino acid sequence of any one of SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, or SEQ ID NO:15; and provided is a pharmaceutical composition comprising a HIV fusion inhibitor peptide and one or more of a pharmaceutically acceptable carrier and macromolecular carrier, and uses and methods of treatment provided by these compositions. | 04-23-2009 |
20100261876 | NOVEL METHODS OF SYNTHESIS FOR THERAPEUTIC ANTIVIRAL PEPTIDES - Provided herein are methods for synthesis of peptides. In particular, provided herein are methods of synthesis for therapeutic antiviral peptides. | 10-14-2010 |
20120040891 | HIV FUSION INHIBITOR PEPTIDES WITH IMPROVED BIOLOGICAL PROPERTIES - Provided is an HIV fusion inhibitor peptide having an amino acid sequence of any one of SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, or SEQ ID NO:15; and provided is a pharmaceutical composition comprising a HIV fusion inhibitor peptide and one or more of a pharmaceutically acceptable carrier and macromolecular carrier, and uses and methods of treatment provided by these compositions. | 02-16-2012 |
Patent application number | Description | Published |
20130201867 | METHOD AND APPARATUS FOR IDENTIFYING A PHYSICAL LINK INTERCONNECTING NETWORK DEVICES - Methods and apparatuses for identifying a physical link interconnecting network devices and/or correlating a designation of an interface on a network device to a physical location of the interface on the network device are disclosed herein. A method for identifying a physical link interconnecting a network device and a peer network device, where the network device and the peer network device each have an interface and a corresponding indicating light, may include: sending a packet from the interface of the network device to the interface of the peer network device over the physical link; causing the indicating light corresponding to the interface of the peer network device to blink at a predetermined cadence for a predetermined period of time upon receipt of the packet to enable recognition of the peer network device. | 08-08-2013 |
20140146051 | Visualization of Question and Related Informational Item Data - Data indicating a plurality of informational items is received at a processor. The data further comprises at least one useful informational item. Also received at the processor is data indicating a plurality of questions, including at least one unanswered question. The processor analyzes the data to determine a number of unanswered questions and a number of useful informational items. The processor generates a visualization comparing the number useful informational items to the number of unanswered questions. The visualization is displayed on a display. | 05-29-2014 |
20140172919 | AUTOMATIC CORRELATION OF DYNAMIC SYSTEM EVENTS WITHIN COMPUTING DEVICES - Systems and methods are described herein for logging system events within an electronic machine using an event log structured as a collection of tree-like cause and effect graphs. An event to be logged may be received. A new event node may be created within the event log for the received event. One or more existing event nodes within the event log may be identified as having possibly caused the received event. One or more causal links may be created within the event log between the new event node and the one or more identified existing event nodes. The new event node may be stored as an unattached root node in response to not identifying an existing event node that may have caused the received event. | 06-19-2014 |
20150128264 | METHOD AND SYSTEM FOR DELEGATING ADMINISTRATIVE CONTROL ACROSS DOMAINS - In one embodiment, a method for delegating partial administrative controls across one or more administrative domains is provided. An upstream network device may advertise capabilities for controlling certain administrative functions to a downstream network device. The downstream network device may chose to act on one or more capabilities, allowing for partial administrative control across the administrative domain. | 05-07-2015 |
20160098419 | AUTOMATIC CORRELATION OF DYNAMIC SYSTEM EVENTS WITHIN COMPUTING DEVICES - Systems and methods are described herein for logging system events within an electronic machine using an event log structured as a collection of tree-like cause and effect graphs. An event to be logged may be received. A new event node may be created within the event log for the received event. One or more existing event nodes within the event log may be identified as having possibly caused the received event. One or more causal links may be created within the event log between the new event node and the one or more identified existing event nodes. The new event node may be stored as an unattached root node in response to not identifying an existing event node that may have caused the received event. | 04-07-2016 |
Patent application number | Description | Published |
20140270634 | MULTI- PURPOSE APPARATUS FOR SWITCHING, AMPLIFYING, REPLICATING, AND MONITORING OPTICAL SIGNALS ON A MULTIPLICITY OF OPTICAL FIBERS - Several useful functions that are included in many modern day fiber optical communication systems are (1) replication of an optical signal on a single optical fiber onto a multiplicity of optical fibers, (2) amplification of optical signals, and (3) sequential switching of optical signals on a large number of optical fibers to a single or limited number of optical fibers that can each be connected to specialized performance monitoring equipment. These functions can be accomplished using a single apparatus called a multi-purpose Switched, Amplifying, Replicating and Monitoring apparatus that can manage as few as 8 optical fibers up to 512 optical fibers, or more by multiplexing. | 09-18-2014 |
20140314385 | HIGH DENSITY ENCLOSURE FOR OPTICAL MODULES - Rack mountable equipment enclosures have been developed that contain a multiplicity of fiber optical component such as optical taps, arrayed waveguide gratings (AWGs), optical splitters, and optical switches at a greater component density than has been previously achieved. For example, 192 fiber optical taps can be contained in a standard 19 inch wide equipment enclosure that is only 1 Rack Unit (1.75 inches) high. This high component density is achieved by locating the optical components within a multiplicity of modular containers inside of the equipment enclosure. The components are connected to fiber optic pig-tails that extend beyond the modular containers. These pig-tails are terminated with multi-fiber connectors that are mounted on the front panel of the equipment enclosure. This strategy allows for efficient packing of the modular containers containing optical components in the full volume of the rack space that is available to the equipment enclosure. | 10-23-2014 |
20140376855 | APPARATUS FOR SELECTIVE FIBER OPTICAL CHANNEL MONITORING AND CHANNEL REPLICATION OF WAVELENGTH DIVISION MULTIPLEXED (WDM) SIGNALS - An apparatus for selective fiber optical channel monitoring and channel replication of wavelength division multiplexed (WDM) signals is constructed by combining a dispersive element, such as an arrayed waveguide grating (AWG), with a multiplicity of simple 1×1 optical switches and either an optical splitter/combiner or a second AWG. In operation, each optical channel in a WDM group may be sequentially monitored or replicated. When this apparatus is preceded by an N×1 optical switch, any optical channel on any one of N input optical fibers to the switch may be selected for monitoring or replication. | 12-25-2014 |
Patent application number | Description | Published |
20080260775 | New Live Virus Vaccines - The present invention provides novel self-replicating and self-propagating chimeric viral vectors and chimeric virus particles comprising a modified genome of a carrier RNA virus packaged within structural proteins of a second virus. Also provided are pharmaceutical formulations comprising the chimeric viral vectors and virus particles and methods of inducing an immune response by administration of the same to a subject. | 10-23-2008 |
20080279891 | Viral Adjuvants - The present invention provides viral adjuvants for enhancing an immune response to an immunogen. In particular embodiments, the viral adjuvant is an alphavirus adjuvant or a Venezuelan Equine Encephalitis viral adjuvant. Also provided are compositions comprising the viral adjuvant and an immunogen, and pharmaceutical formulations comprising the viral adjuvant or compositions of the invention in a pharmaceutically acceptable carrier. Further provided are methods of producing an immune response against an immunogen in a subject comprising administering the immunogen and a viral adjuvant of the invention to the subject. | 11-13-2008 |
20090162395 | VACCINE FOR RSV AND MPV - The present invention is directed to alphavirus vectored vaccine contructs encoding paramyxovirus proteins that find use in the prevention of respiratory syncytial virus or human metapneumovirus infections. In particular, these vaccines induce cellular and humoral immune responses that inhibit RSV. Also disclosed are improved methods for producing alphavirus vectored paramyxovirus vaccines. | 06-25-2009 |
20110064772 | VIRAL ADJUVANTS - The present invention provides viral adjuvants for enhancing an immune response to an immunogen. In particular embodiments, the viral adjuvant is an alphavirus adjuvant or a Venezuelan Equine Encephalitis viral adjuvant. Also provided are compositions comprising the viral adjuvant and an immunogen, and pharmaceutical formulations comprising the viral adjuvant or compositions of the invention in a pharmaceutically acceptable carrier. Further provided are methods of producing an immune response against an immunogen in a subject comprising administering the immunogen and a viral adjuvant of the invention to the subject. | 03-17-2011 |
20120121650 | Chimeric Virus Vaccines - The present invention provides novel self-replicating and self-propagating chimeric viral vectors and chimeric virus particles comprising a modified genome of a carrier RNA virus packaged within structural proteins of a second virus. Also provided are pharmaceutical formulations comprising the chimeric viral vectors and virus particles and methods of inducing an immune response by administration of the chimeric viral vectors and virus particles or nucleic acids (e.g., DNA and/or RNA) encoding the same to the subject. | 05-17-2012 |
Patent application number | Description | Published |
20080259930 | Message Flow Model of Interactions Between Distributed Services - A computer-implementable method, system and computer-usable medium for defining a message flow model of interactions between distributed services are presented. In a preferred embodiment, the method includes the steps of: capturing unidirectional network-level message traffic between services in a network; identifying service end-points from information obtained from the uni-directional network-level message traffic; identifying message interactions of captured uni-directional network-level message traffic between identified service end-points; applying formal and informal interface definitions to the captured unidirectional network-level message traffic; categorizing each captured unidirectional network-level message traffic as being a public network-level message traffic or a private network-level message traffic; filtering the captured uni-directional network-level message traffic to filter out any formally defined captured uni-directional network-level message traffic; correlating message exchanges for filtered uni-directional network-level message traffic to identify a relationship between correlated message exchanges; and analyzing the network according to identified relationships between correlated message exchanges. | 10-23-2008 |
20080313597 | System and Method for Describing Method Process Using Guided Architectural Decisions - A method author uses a method generator to create a customized project-specific method that includes first class decision elements. The decision elements are included in a meta model for a process framework, and describe actual decisions for a user to resolve. Once created, a method advisor uses the project-specific method to guide a user through architectural decisions by refining the project-specific method's process flow based upon the user's decisions. The refining includes removing activity elements and decision elements from the process flow that are not reachable by a path corresponding to the user's choice selection. The method advisor also stores the user's choice selections, along with considerations, conditions, and consequences, for the use to view at a later date. | 12-18-2008 |
20090105941 | AUTOMATIC DESTINATION DETERMINATION FOR MULTIPLE TRAVELERS DEPARTING FROM MULTIPLE SOURCE LOCATIONS BASED ON USER SPECIFIED CRITERIA - The present invention discloses a software implemented solution for automatically determining a travel destination. The method can identify a set of source locations, each source location representing a starting location of a traveler. Criteria for a destination to which each of the travelers is to travel can then be identified. At least one destination can be determined based upon the identified criteria. Directions for traveling from each of the source locations to the determined destination can be constructed. | 04-23-2009 |
20090138249 | DEFINING OPERATIONAL ELEMENTS IN A BUSINESS PROCESS MODEL - Embodiments of the invention provide a method, system and computer program product for rendering a process model through a configuration of a unitary operational element in the process modeling data processing system. The method can include parsing semantic elements in a semantic process model and identifying different types for the semantic elements as well as different connections amongst the semantic elements in the semantic process model. The method further can include initializing a visual model to include instances of a unitary operational element, and for each of the semantic elements, an instance of a unitary operational element can be configured in the visual model with zero or more inbound and outbound connections according to an identified type and connecting paths between respective outbound and inbound connections of different instances of the unitary operational element based upon the different connections amongst the semantic elements. Finally, the visual model can be displayed. | 05-28-2009 |
20090187573 | REPRESENTING MODELS IN SYSTEMS DEVELOPMENT LIFECYCLE (SDLC) TOOLS USING A NETWORK OF INTERNET RESOURCES - In the present solution, as set of SDLC resources can be established, where each is separately addressable through a unique URL and is able to be managed through a simple set of operations. For example, a set of RESTful operations (GET, POST, PUT, and DELETE) can be used for the operations. Database management technologies can be leveraged for storing and indexing resources, but the underlying database schema for the solution can operate on a resource level, which results in the resources being stored as-is. Thus, storage (even when database based) of resources for the solution can be considered an Internet server exposing a space of URL addressable objects. Because the solution leverages Internet technologies and standards, it is scalable, standards based, extensible, and traceable. | 07-23-2009 |
20110125904 | INDEXING HETEROGENOUS RESOURCES - Resources are typically stored in homogenous data structures by shredding resource data into database tables destroying a native format of the resources. Typical approaches to indexing the resources rely on users indicating properties that should be indexed, using full text searches to create resource index documents, and other such labor and computation intensive processes. Functionality can be implemented to dynamically generate the resource index documents based on resource properties with minimal user input. The resource index documents can be in a_common format to facilitate access to resources stored in heterogeneous native resource formats. | 05-26-2011 |