Anderson, CT
Amy C. Anderson, Storrs, CT US
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20090105287 | Inhibitors of Dihydrofolate Reductase With Antibacterial Antiprotozoal, Antifungal and Anticancer Properties - The compositions and methods described herein discloses the design, synthesis and testing of compounds that act as inhibitors of DHFR. The basic scaffold of these inhibitors includes a 2,4-diaminopyrimidine ring with a propargyl linker to another substituted aryl, bicyclo or heteroaryl ring. These DHFR inhibitors are potent and selective for many different pathogenic organisms, including the DHFR enzyme from bacteria such as | 04-23-2009 |
20120196859 | HETEROCYCLIC ANALOGS OF PROPARGYL-LINKED INHIBITORS OF DIHYDROFOLATE REDUCTASE - The compositions and methods described herein disclose the design, synthesis and testing of compounds that act as inhibitors of DHFR. The basic scaffold of these inhibitors includes a 2,4-diaminopyrimidine ring with a propargyl linker to another substituted aryl, bicyclo or heteroaryl ring. These DHFR inhibitors are potent and selective for many different pathogenic organisms, including the DHFR enzyme from bacteria such as | 08-02-2012 |
20150225353 | Heterocyclic and Cyclic Analogs of Propargyl-Linked Inhibitors of Dihydrofolate Reductase - Compounds of Formula I and Formula IA are inhibitors of dihydrofolate reductase and are suitable for use in compositions and methods for dihydrofolate reductase inhibition or, more specifically, treatment of a fungal infection, a bacterial infection or a protozoal infection, and, in specific embodiments, treatment of a fungal infection caused by | 08-13-2015 |
Barbara Anderson, Brookfield, CT US
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20120153958 | METHODS FOR DETERMINING DIELECTRIC PERMITTIVITY SPECTRUM OF UNDERGROUND ROCK FORMATIONS - A method for determining the frequency-dependent dielectric permittivity spectrum of a rock sample, comprising:—defining a series of electromagnetic measurement data comprising at least a first measurement at a frequency from which a substantially frequency-independent value of dielectric permittivity ∈ | 06-21-2012 |
Barbara Anderson, Brookfield Center, CT US
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20150025807 | Methods for Determining Dielectric Permittivity Spectrum of Underground Rock Formations - Techniques involve determining the frequency-dependent dielectric permittivity spectrum of a rock sample. Determining the frequency-dependent dielectric permittivity may involve defining a series of electromagnetic measurement data having at least a measurement at a frequency from which a substantially frequency-independent value of dielectric permittivity ε | 01-22-2015 |
Barbara I. Anderson, Brookfield, CT US
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20110309835 | METHOD FOR DETERMINING SPATIAL DISTRIBUTION OF FLUID INJECTED INTO SUBSURFACE ROCK FORMATIONS - A method for determining spatial distribution of fluid injected into a subsurface rock formation includes injecting the fluid into the rock formation. The fluid includes therein electrically conductive solid particles dispersed in an electrolyte. An electromagnetic response of the formation is measured. The measured electromagnetic response is used to determine spatial distribution of the injected fluid. | 12-22-2011 |
Carney R. Anderson, East Haddam, CT US
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20110176925 | TORSIONAL FLEXING ENERGY ABSORBING BLADE LOCK - A lock for constraining blades in a hub includes a flexible ring for constraining the blades from moving axially in the hub, a finger attached to the hub for preventing the ring from rotating relative to the hub and whereby the ring flexes about at least a partial circumference thereof if urged axially by the blades. | 07-21-2011 |
20130052026 | AXIAL RETENTION SYSTEM FOR A BLADED ROTOR WITH MULTIPLE BLADE TYPES - A bladed rotor includes a blade lock mountable to a rotor hub adjacent to a multiple of blade slots. The blade lock includes at least one interface feature adjacent to a first of the multiple of blade slots. A first rotor blade includes a blade feature which interfaces with the interface feature to permit the first rotor blade to be axially mounted within the first of the multiple of blade slots but not within a remainder of the multiple of blade slots. | 02-28-2013 |
20130156584 | COMPRESSOR ROTOR WITH INTERNAL STIFFENING RING OF DISTINCT MATERIAL - A compressor rotor has a hub at a radially outer location, and a leg extending from an inner ring at a radially inner location to the hub. The hub has an inner bore at a location spaced from the leg. A stiffening ring is force fit into the inner bore of the hub. | 06-20-2013 |
20140056713 | TURBINE ENGINE ROTOR ASSEMBLY - A turbine engine rotor assembly includes a turbine engine rotor disk that extends axially along a centerline between a first disk end and a second disk end, and radially to an outer disk surface. The rotor disk includes one or more blade retention slots arranged circumferentially around the centerline. A first of the blade retention slots extends axially into the rotor disk from a disk end surface at the first disk end to a slot end surface, and radially into the rotor disk from the outer disk surface to a slot base surface. | 02-27-2014 |
20140070794 | SENSOR AND TOOTH ARRANGEMENT FOR SHAFT SPEED DETECTION - A non-ferrous shaft includes multiple non-integral ferrous tooth components, thereby allowing a sensor to detect the shaft speed. | 03-13-2014 |
20140127007 | GAS TURBINE ENGINE ROTOR SEAL - A rotary seal for sealing a bladed rotor of a gas turbine engine to a stator thereof comprises a sealing element and a sealing element support comprising a radially outer edge portion on which the sealing element is fixed, a radially inner mounting portion adapted to be attached to a supported rotor hub, and a flexible, medial web portion extending between the radially outer edge portion and the radially inner mounting portion. | 05-08-2014 |
20140133991 | GAS TURBINE ENGINE FAN BLADE LOCK ASSEMBLY - A gas turbine engine fan blade lock assembly includes a fan hub that has blade slots each configured to receive a root of a fan blade. The fan hub includes circumferentially spaced first slots. A lock ring is configured to move between unlocked and locked positions. The lock ring includes circumferentially spaced second slots aligned with the first slots in the locked position, and multiple discrete pins. Each pin is configured to be slidably received in paired first and second slots in the locked position to prevent rotational movement of the lock ring relative the fan hub. | 05-15-2014 |
20140199176 | GAS TURBINE ENGINE NOSE CONE ATTACHMENT CONFIGURATION - A gas turbine engine fan section includes a fan hub configured to rotate about an axis. A nose cone includes a spinner operatively mounted to the fan hub. The spinner supports a first fastening element and the nose cone includes an annular cover arranged over the fastening element. The spinner and annular cover provide an aerodynamic exterior surface of the nose cone without exposed fasteners. A second fastening element cooperates with the first fastening element to secure the spinner relative to the fan hub. The first and second fastening elements are oriented transversely to the axis. | 07-17-2014 |
20140255196 | DOUBLE SPLIT BLADE LOCK RING - A rotor assembly for a gas turbine engine includes a plurality of blades including a root portion and an airfoil portion. The rotor includes a plurality of slots that receive the root portion of a corresponding blade. The rotor includes an annular groove for a first and second retaining ring. The retaining rings are received within a common annular groove for holding each of the plurality of blades within the slots of the rotor. | 09-11-2014 |
20150361804 | GAS TURBINE ENGINE NOSE CONE ATTACHMENT - A fan section for a gas turbine engine includes a fan hub having blade slots for receiving a root of a fan blade. A lock ring is configured to move rotatably from an unlocked position to a locked position for securing the blade root in the blade slot. A nose cone is secured to the lock ring, and thereby secured to the fan section. | 12-17-2015 |
Christopher S. Anderson, Westport, CT US
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20120312944 | Sign Holder and Coupon Dispenser - A system for mounting a sign on a store shelf comprises a mounting bracket for mounting a sign holder to the C-channel commonly found on the edge of shelves. The mounting bracket has a mounting face coupled to a channel anchor. The sign holder is affixed to the mounting face and the channel anchor is affixed to the C-channel. The mounting face and channel anchor are pivotably coupled to allow the angle there between to be adjustable. Bumps on the channel anchor and corresponding dimples on the mounting face may be provided to allow adjustment of the angle when a mounting screw is loosed and locking in of the angle when the mounting screw is tightened. | 12-13-2012 |
Clark David Anderson, Barkhamsted, CT US
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20110076146 | Wind turbine electrical generating system with combined structural support members and straightening vanes - A wind turbine electrical-generating system with air-directing vanes in the forms of sheaths over structural members crossing the sir discharge opening of the wind turbines. The turbines also have associated shroud assemblies which support the structural members and which cooperate with the vanes to provide superior performance. | 03-31-2011 |
20110131917 | Method of forming adhesive joint, structural subassembly, and joint construction - A method of forming an adhesive joint, a structural subassembly, and a joint construction. The method comprises telescopically assembling male and female tubular members having slightly different diameters to cooperatively define a narrow continuous open-end adhesive chamber between contiguous surfaces of the assembled members. Four (4) or more centering pins equally circumaxially spaced about the members are forcefully entered in the adhesive chambers to equalize spacing between the members throughout the chamber. A distributing device communicates with the adhesive chamber for the introduction of adhesive under pressure to the chamber, thus forming a secure joint. | 06-09-2011 |
David D. Anderson, Groton, CT US
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20100029686 | HCV PROTEASE INHIBITORS AND USES THEREOF - This invention relates to: (a) compounds of formula I and salts thereof that, inter alia, are useful as hepatitis C virus (HCV) inhibitors; (b) intermediates useful for the preparation of such compounds and salts; (c) pharmaceutical compositions comprising such compounds and salts; and (d) methods of use of such compounds, salts, and compositions. | 02-04-2010 |
20110160233 | ANTI-VIRAL COMPOUNDS - Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections. | 06-30-2011 |
20130303547 | HCV Protease Inhibitors and Uses Thereof - This invention relates to: (a) compounds of formula I and salts thereof that, inter alia, are useful as hepatitis C virus (HCV) inhibitors; (b) intermediates useful for the preparation of such compounds and salts; (c) pharmaceutical compositions comprising such compounds and salts; and (d) methods of use of such compounds, salts, and compositions. | 11-14-2013 |
David R. Anderson, Salem, CT US
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20150141433 | N-ARYLMETHYL SULFONAMIDE NEGATIVE MODULATORS OF NR2A - Compounds that selectively negatively modulate NMDA receptors containing an NR2A subunit, pharmaceutical compositions comprising the compounds, and methods of treating a disease using the compounds are disclosed. | 05-21-2015 |
20150225342 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C] PYRROLE NEGATIVE MODULATORS OF NR2B - Compounds that selectively negatively modulate NMDA receptors containing an NR1/NR2B subunit, pharmaceutical compositions comprising the compounds, and methods of treating a disease using the compounds are disclosed. | 08-13-2015 |
David Randolph Anderson, Salem, CT US
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20150284405 | Bicyclic-Fused Heteroaryl or Aryl Compounds - Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia, | 10-08-2015 |
David W. Anderson, South Windsor, CT US
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20130145607 | FITTING FOR USE WITH NUT WITH INTERNAL LOCKING MECHANISM - A fitting for use with a nut with an internal locking mechanism includes a first tubular portion with a first end and a first outer diameter for connecting to a first object; a second tubular portion with a second end and a second outer diameter for connecting to a second object; a transition portion connecting the first tubular portion and the second tubular portion for fluid communication between the first tubular portion and the second tubular portion; and a plurality of pockets spaced circumferentially around the second tubular portion to engage the internal locking mechanism of the nut. | 06-13-2013 |
20130147182 | FERRULE - A ferrule for use with a nut with an internal locking mechanism includes a first tubular portion with a first end and a first outer diameter for connecting to a first object; a second tubular portion with a second end and a second outer diameter for connecting to a second object; a transition portion connecting the first tubular portion and the second tubular portion; and a plurality of pockets spaced circumferentially around the second portion to engage the internal locking mechanism of the nut. | 06-13-2013 |
David W. Anderson, Cromwell, CT US
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20140090753 | METHOD FOR SOLUTION HEAT TREATED ALLOY COMPONENTS - A method for adjusting properties of components made of an alloy includes providing historical data for one or more properties of components made of an alloy and produced at different times. The components are solution heat treated at a pre-established solution heat treatment condition. A trending change in the one or more properties is then identified and test specimens made of the alloy are provided. The test specimens are divided into a plurality of groups and solution heat treated at different conditions. The test specimens are then mechanically tested to provide empirical data. The empirical data is compared to performance criteria and a solution heat treatment condition is identified over which the empirical data meets the performance criteria. The pre-established solution heat treatment condition is then adjusted for future ones of the plurality of components according to the identified solution heat treatment condition. | 04-03-2014 |
Derek W. Anderson, Cromwell, CT US
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20080216300 | Splitter fairing repair - A defect in a splitter fairing of a turbine engine is repaired by removing a forward portion of the splitter fairing and salvaging the remaining original portion of the splitter fairing. The forward portion includes an inner flange and outer surface that create a channel. A replacement ring is provided and welded to the original portion. The replacement ring has minimum dimensions equal to the maximum height and width of the removed forward portion. Material from the replacement ring is then removed to obtain a profile with essentially the same profile for the inner flange, outer surface, and channel as the original dimensions of the splitter fairing before the defect occurred. | 09-11-2008 |
20090011123 | Corrosion protective coating through cold spray - Methods for repairing gas turbine components damaged by corrosion that not only restores the components back to their original dimensions to ensure proper engine operations, but also have the added benefit of mitigating future corrosion attacks thereby extending the useful life of the components. | 01-08-2009 |
20090064479 | Methods for Performing Gas Turbine Engine Casing Repairs and Repaired Cases - Methods for repairing gas turbine engine casings and repaired casings are provided. In this regard, a representative method for repairing a gas turbine engine casing includes: removing an annular portion of the engine casing; and attaching an annular replacement portion to the engine casing. | 03-12-2009 |
20090104003 | Gas Turbine Engines Systems and Related Methods Involving Dimensionally Restored Fasteners - Gas turbine engines systems and related methods involving dimensionally restored fasteners are provided. In this regard, a representative method for dimensionally restoring a mechanical fastener for a gas turbine engine includes: providing a mechanical fastener; and relocating existing material of the fastener such that a dimension of the fastener is restored. | 04-23-2009 |
20140234098 | TURBINE CASE RETENTION HOOK WITH INSERT - A method of repairing a turbine engine case includes the steps of removing worn material from a retention hook in a casing, and inserting an insert into a recess within the hook. | 08-21-2014 |
D. Karl Anderson, Meriden, CT US
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20130216566 | Vectors expressing SARS immunogens, compositions containing such vectors or expression products thereof, methods and assays for making and using - SARS (severe acute respiratory syndrome virus, a coronavirus) immunogens, antigens, or epitopes, nucleic acid molecules encoding such immunogens, antigens, or epitopes; vectors containing such nucleic acid molecules, e.g., viral vectors such as baculovirus vectors, DNA vectors, such as DNA plasmid vectors, e.g., DNA plasmids that express a nucleic acid molecule in a mammalian cell, uses for such immunogens, antigens or epitopes and vectors, e.g., as an active component immunogenic, immunological or vaccine compositions, or to generate antibodies, such as monoclonal antibodies, and methods for making, and using such immunogens, antigens or epitopes, vectors, antibodies, including in methods for eliciting an immunological or immunogenic or vaccine response, as well as in assays or diagnostic kits or methods, are discussed, as well as a seamless fusion of sequences in a plasmid or vector, e.g., a sequence encoding a leader sequence and a sequence encoding a protein, epitope or immunogen or antigen. | 08-22-2013 |
Douglas K. Anderson, South Windsor, CT US
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20140332212 | COMPOSITIONS AND METHODS FOR ENHANCED HYDROCARBON RECOVERY - Compositions of and methods of using a fluid formulation for increasing flow, production, and/or recovery of oil and gas hydrocarbons from a subterranean formation. | 11-13-2014 |
20140335140 | NATURAL VOLATILE PLANT OILS TO REPEL ARTHROPODS - A composition and method for the controlled release of natural plant oils (essential oils) from a wax matrix to repel insects, arachnids, and other arthropods. | 11-13-2014 |
Douglas K. Anderson, Bloomfield, CT US
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20100185039 | METHOD FOR EXTRACTION AND SURFACTANT ENHANCED SUBSURFACE CONTAMINANT RECOVERY - Methods and compositions for removing contaminants from soil and groundwater by extracting the contaminants and assisting the extraction by provision of an oxidant introduced prior to or simultaneously with a surfactant into the subsurface. Extractable contaminant can be extracted from the subsurface. The amount and/or distribution of contaminant in the subsurface can be characterized. The extracting of contaminant and the introducing of oxidant and surfactant can be coordinated to reduce contaminant to a target amount. A portion of the contaminant can be oxidizable. | 07-22-2010 |
Everett Bragg Anderson, Glastonbury, CT US
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20080236396 | GAS RECOVERY SYSTEM - A gas recovery system is disclosed. The gas recovery system includes a gas source productive of a gaseous stream comprising moisture, a gas dryer in fluid communication with and downstream of the gas source, and an electrochemical compressor in fluid communication with and downstream of the gas dryer. The gas dryer is disposed to receive the gaseous stream and produce a delivery stream absent moisture and a slipstream comprising moisture. The electrochemical compressor is disposed to receive the slipstream at a first pressure and produce a compressed stream at a second pressure greater than the first pressure. | 10-02-2008 |
20090272271 | GAS RECOVERY SYSTEM - A gas recovery system is disclosed. The gas recovery system includes a gas source productive of a gaseous stream comprising moisture, a gas dryer in fluid communication with and downstream of the gas source, and an electrochemical compressor in fluid communication with and downstream of the gas dryer. The gas dryer is disposed to receive the gaseous stream and produce a delivery stream absent moisture and a slipstream comprising moisture. The electrochemical compressor is disposed to receive the slipstream at a first pressure and produce a compressed stream at a second pressure greater than the first pressure. | 11-05-2009 |
Gary F. Anderson, Danbury, CT US
Hans C. Anderson, Stratford, CT US
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20150350737 | System and Method for Multi-Device Video Image Display and Modification - Methods and systems for allowing multiple devices to display and annotate (or modify) a video image are described, where a content renderer device displays a video image that is also displayed (or viewed) by one or more content viewer devices, which can both display and annotate (or modify) the same video image at the same time, and the content renderer selectively determines whether or not a GUI menu is displayed on its display screen. Annotation commands (e.g., screen touch data) on the viewer devices are captured, packaged and sent to the content renderer, which creates a combined modified video image having the annotations from the viewer devices, displays it to the renderer display and sends it to the viewer devices for display thereon. Also, the viewer device may selectively display video content from multiple other peer devices as a composite video image, may annotate (or modify) each displayed video content independently, and may send a screen video image, or a portion thereof, to any other peer device. Any peer device may operate as a content renderer or content viewer, or both, at any given time, and peer devices may be running different operating systems. | 12-03-2015 |
James S. Anderson, Bethel, CT US
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20120078016 | Methods of Synthesizing 2-Substituted-1,4-Benzenediamine - Disclosed is a method of making a 2-substituted-1,4-benzenediamine by nucleophilic aromatic substitution. | 03-29-2012 |
20140081049 | METHODS OF SYNTHESIZING 2- SUBSTITUTED-1,4-BENZENEDIAMINE - Disclosed is a method of making a 2-substituted-1,4-benzenediamine by nucleophilic aromatic substitution. | 03-20-2014 |
Jay Brian Anderson, Coventry, CT US
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20150136045 | EVAPORATOR APPARATUS AND METHOD OF OPERATING THE SAME - A heat exchanger apparatus for receiving water from a steam drum ( | 05-21-2015 |
Karen S. Anderson, Guilford, CT US
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20110312880 | POTENT CHIMERIC NRTI-NNRTI BIFUNCTIONAL INHIBITORS OF HIV-1 REVERSE TRANSCRIPTASE - The present invention relates to compounds, in particular, dual antagonists comprising a nucleoside reverse transcriptase inhibitor (NRTI) or a nucleoside competititive reverse transcriptase inhibitor and a non-nucleoside reverse transcriptase inhibitor (NNRTI), linked together using a chemical linker, which may be used to inhibit HIV (HIV-1) reverse transcriptase and in the treatment of HIV infections, more severe cases of HIV infections, including ARC and AIDS, including reducing the likelihood of these infections and disease states. | 12-22-2011 |
20140288017 | CATECHOL DIETHERS AS POTENT ANTI-HIV AGENTS - The present invention is directed to novel catechol diether compounds, pharmaceutical compositions therefrom and methods for inhibiting reverse transcriptase and treating HIV infections, especially included drug resistant strains of HIV 1 and 2 and/or secondary disease states and/or conditions which occur as a consequence of HIV infection. | 09-25-2014 |
20140378443 | Novel Compositions and Methods of Treating HIV-1 Infections Using Same - The present invention includes novel compositions useful for preventing or treating an HIV-1 infection in a subject in need thereof. The present invention further includes a novel method of preventing or treating an HIV-1 infection in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound of the invention. In one embodiment, the subject is further administered at least one additional therapeutic agent. | 12-25-2014 |
20150105351 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS - The present invention is directed to novel nanomolar and picomolar inhibitors of HIV reverse transcriptase, pharmaceutical compositions therefrom and methods for inhibiting reverse transcriptase and treating HIV infections, especially included drug resistant strains of HIV-1 and HIV-2 and/or secondary disease states and/or conditions which occur as a consequence of HIV infection. | 04-16-2015 |
Kristopher K. Anderson, Manchester, CT US
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20150211376 | TURBINE VANE COOLING ARRANGEMENT - A vane includes a pair of airfoils that have a plurality of film cooling holes that extend through an exterior surface of the airfoils. Each plurality of film cooling holes break through the exterior surface at geometric coordinates in accordance with Cartesian coordinate values of X, Y and Z as set forth in Table 1. Each geometric coordinates is measured from a reference point on a leading edge rail of a platform of the vane. | 07-30-2015 |
Lynne Anderson, Greenwich, CT US
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20120311773 | Braided goggle strap - The present invention is directed to a braided goggle strap for use with a pair of swimming goggles. The braided goggle strap includes a plurality of resilient bands that are braided together to form a flat, braided goggle strap having superior mechanical properties that provides even stress distribution and minimal sinusoidal stress when worn by a user. The composite reinforcement of the braided goggle strap also provides added comfort. The braided goggle strap includes a spring-biased fastener for adjustably attaching the braided strap onto a user's head, is easily attachable to a pair of swimming goggles by simply threading the braided strap through apertures provided on the goggles, and comes in a variety of different colors. | 12-13-2012 |
Lynne Anderson, Old Greenwich, CT US
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20150290037 | Braided goggle strap - A braided goggle strap for use with a pair of swimming goggles includes a plurality of bands that are braided together to form a generally flat, braided goggle strap. Each of the plurality of bands includes an elastic material that is protected by a resilient fabric material to provide superior mechanical properties that results in even stress distribution and minimal sinusoidal stress when worn by a user. The composite reinforcement of the braided goggle strap also provides added comfort. The braided goggle strap includes a biased fastener for adjustably attaching the braided strap onto a user's head, is easily attachable to a pair of swimming goggles by simply threading the braided strap through the small apertures provided on the swimming goggles, and comes in a variety of different colors. | 10-15-2015 |
Mark Richard Anderson, Stamford, CT US
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20150206416 | PAYMENT CARD LOCATION METHOD AND APPARATUS - A system, method, and computer-readable storage medium configured to track the location of lost payment cards. | 07-23-2015 |
Neil E. Anderson, Berlin, CT US
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20160002747 | PROCESS FOR TREATING STEEL ALLOYS FOR GEARS - A process for treating a steel alloy component includes the steps of: providing a steel alloy component having a plurality of teeth with a root portion and a tip; and processing the steel alloy so that the root portion of the gear teeth are hardened without through hardening of the tips of the gear teeth. | 01-07-2016 |
Raymond Oliver Anderson, Bridgeport, CT US
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20140360522 | HAIR MANAGEMENT PROCESS - A hair management process includes washing the hair and scalp, towel drying the hair and leaving the hair damp, applying an oil composition to the scalp, applying hair moisturizer to the hair and scalp, covering the hair with a cap, removing the cap and applying hair moisturizer to the hair, applying hair mousse on top of the moisturizer and styling the hair. | 12-11-2014 |
Stephen R. Anderson, Stonington, CT US
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20150080567 | Method to Produce and Scale-Up Cocrystals and Salts Via Resonant Acoustic Mixing - A method to produce and manufacture cocrystals and salts is disclosed wherein crystalline solids and other components were combined in the desired proportions into a mixing chamber and mixed at high intensity to afford a cocrystalline product. No grinding media were required. The mixing system consists of a resonant acoustic vibratory system capable of supplying a large amount of energy to the mixture and is tunable to a desired resonance frequency and amplitude. The use of resonant acoustic mixing to assist cocrystallization is novel. This discovery enables the manufacture of cocrystals and salt forms, simplifying their manufacture and scale-up, and avoiding the use of grinding methods or grinding media. The present invention affords the manufacture of cocrystals and salts on kilogram to multi-ton scale and is adaptable to continuous manufacturing through the use of resonant mixing methods. | 03-19-2015 |
20150361056 | CL-20:DNMT COCRYSTAL CRYSTAL STRUCTURE - A cocrystal of CL-20 (2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane) and DNMT (1-methyl-3,5-dinitro-1,2,4-triazole) was formed through a resonant acoustic mixing process. The resulting cocrystal comprised an essentially 1:1 stoichiometric ratio between these coformers. The cocrystal advantageously has decreased sensitivity when compared with a pure CL-20 sample, and maintains thermal stability and comparable energetic performance. | 12-17-2015 |
Tom H. C. Anderson, Stamford, CT US
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20130036126 | NATURAL LANGUAGE TEXT ANALYTICS - A method of text analytics includes filtering a plurality of unfiltered records having unstructured data into at least a first group and a second group. The first group and said second group each include at least two records and the first group is different than the second group. The method includes determining a first proportion of occurrence for a term by comparing a first number of records having at least one occurrence of the term in the first group to a first total number of records in the first group, determining a second proportion of occurrence for the term by comparing a second number of records having at least one occurrence of the term in said second group to a second total number of records in the second group, and comparing the first proportion of occurrence to the second proportion of occurrence to yield a resultant comparison occurrence. | 02-07-2013 |