Patent application number | Description | Published |
20080215140 | STENTS COATED WITH BIOMOLECULES AND PROCESS FOR THEIR PRODUCTION - A stent comprising a basic stent body, at least one anchor group on the surface of the basic stent body, and at least one biomolecule which is bound to the at least one anchor group, the anchor group being the same or different and selected from the group of compounds with the general formula (I) | 09-04-2008 |
20080234790 | Implantable Stimulation Electrode with a Coating for Increasing Tissue Compatibility - An implantable stimulation electrode for use with an implantable tissue stimulator, especially a pacemaker, a defibrillator, a bone stimulator or a neurostimulator includes a metal base body, optionally one or more intermediate layers disposed on the base body and a coating covering the base body and, optionally, intermediate layers in order to increase tissue compatibility. The coating should prevent tissue irritations after implantation and more particularly increase the stimulus threshold associated therewith, have very high biocompatibility and also has an anti-inflammatory effect. An increase in tissue compatibility is achieved by virtue of the fact that the coating has a polysaccharide layer made of hyaluronic acid and/or hyaluronic acid derivatives. | 09-25-2008 |
20090076596 | STENT HAVING A COATING - A stent having a coating comprising either L-3,4-dihydroxyphenylalanine (L-DOPA) or a derivative of L-3,4-dihydroxyphenylalanine (L-DOPA), the foregoing obtained by either ionic or covalent bonding of a pharmaceutical active ingredient to either the amino or the acid function of L-3,4-dihydroxyphenylalanine (L-DOPA). | 03-19-2009 |
20090112307 | STENT HAVING A BASE BODY OF A BIOINERT METALLIC IMPLANT MATERIAL - A stent having a base body of a bioinert metallic implant material wherein the base body is covered with an SiC coating. An external surface of the base body has a plurality of cavities which are filled with an antiproliferative active ingredient, A luminal surface of the base body has a coating which contains or comprises attractors for endothelial cells. | 04-30-2009 |
20090192594 | IMPLANT HAVING A BASE BODY OF A BIOCORRODIBLE ALLOY AND A CORROSION-INHIBITING COATING - An implant having a base body consisting entirely or in part of a biocorrodible metallic material wherein at least the parts of the base body made of the biocorrodible metallic material are covered with a corrosion-inhibiting coating. The coating comprises a primer layer of a first biodegradable polymer material comprising a poly(D,L-lactide) (PDLLA) with a degree of polymerization in the range of 5 to 20 and a protective layer of a second biodegradable polymer material comprising a diblock copolymer (PEG/PLGA) of polyethylene glycol (PEG) and poly(D,L-lactide-co-glycolide) (PLGA) applied to the primer layer. | 07-30-2009 |
20090270977 | STENT FIXATION SYSTEM - A stent fixation system | 10-29-2009 |
20090274737 | IMPLANT COMPRISING A SURFACE OF REDUCED THROMBOGENICITY - An implant for a human or animal body, comprising a surface having reduced thrombogenic properties, whose surface has a wetting angle of Θ, where Θ≦80°. Also disclosed is a method for producing an implant and the use an implant to reduce the dose or concentration in administration of a concomitant systemic medication with one or more anticoagulant active ingredients before, during or after implantation of the implant in a human or animal body. | 11-05-2009 |
20090311304 | DRUG-LOADED IMPLANT - The invention relates to a drug-loaded implant having a carrier body ( | 12-17-2009 |
20100015201 | IMPLANT WITH COATING - The present invention concerns an implant with a molecularly imprinted polymer coating, a process for its synthesis, a molecularly imprinted polymer, as well as a process for its synthesis and its use as well as a process for the treatment or prophylaxis of certain disease conditions by implantation of an implant in accordance with the invention according to the respective independent claims. | 01-21-2010 |
20100023112 | BIOCORRODIBLE IMPLANT WITH A COATING COMPRISING A HYDROGEL - The invention relates to an implant having a base body consisting completely or partially of a biocorrodible metallic material, the material being such that it decomposes in an aqueous environment to yield an alkaline product and the base body has a coating comprising or containing a hydrogel, characterized in that the hydrogel has a reduced swelling capacity at an elevated pH. | 01-28-2010 |
20100023116 | BIOCORRODIBLE IMPLANT WITH A COATING CONTAINING A DRUG ELUTING POLYMER MATRIX - The invention relates to an implant having a base body, consisting completely or partially of a biocorrodible metallic material, such that it decomposes in an aqueous environment to form an alkaline product, and the base body has a coating or a cavity filling, comprising a polymer matrix and at least one drug embedded in the polymer matrix, characterized in that at least one polymer of the matrix and the at least one drug are coordinated so that the drug elution rate from the matrix is increased with an increase in pH. | 01-28-2010 |
20100119581 | Medical Products That Release Pharmaceutically Active Substances - The present invention concerns medical products that release pharmaceutically active substances, the efficiency of which is increased as the result of a combination with an inhibitor of the transport protein P-glycoprotein. | 05-13-2010 |
20100331966 | BIOCORRODIBLE IMPLANT HAVING AN ACTIVE COATING - One embodiment of the invention relates to an implant having a basic body composed of a biocorrodible material and having an active coating or filling of a cavity, consisting of or containing the components
| 12-30-2010 |
20110034990 | BIOCORRODIBLE IMPLANT WITH ACTIVE COATING - One embodiment of the invention concerns an implant with a basic body of biocorrodible, metallic implant material with an active coating and/or cavity filling. | 02-10-2011 |
20110034996 | MEDICAL IMPLANT CONTAINING AN ANTIOXIDATIVE SUBSTANCE - One embodiment of the invention concerns a medical implant with the basic body having an antioxidative substance. | 02-10-2011 |
20110150964 | APTAMER-COATED IMPLANT, PROCESS OF PRODUCTION, AND USES - One embodiment of the present invention is an implant with an aptamer coating, wherein the aptamer has an activating effect on the α | 06-23-2011 |
20110152766 | IMPLANT WITH COATING - One embodiment of the invention relates to an implant with a coating containing at least one active pharmaceutical substance. The inventive implant is characterized in that the coating is covered by a protective layer comprising or containing one or more materials from the group including shellac, vinylpyrrolidone-vinyl acetate copolymer, vinyl acetate-crotonic acid copolymer, vinyl acetate-vinyl propionate-crotonic acid terpolymer, methylvinyl ether-maleic anhydride copolymer, vinylpyrrolidone-dimethylaminoethyl acrylate copolymer, polyvinylpyrrolidone, polyvinyl acetate, polycrotonic acid, polyvinyl propionate, polymethylvinyl ether, polymaleic anhydride and polydimethylaminoethyl acrylate. | 06-23-2011 |
20110230831 | BALLOON CATHETER HAVING COATING - An embodiment of the present invention relates to a balloon catheter, which has a drug-releasing coating and/or cavity filling on at least parts of the outwardly facing surface of the dilatable balloon, characterized in that the coating comprises a drug and a gelatin mixture, the gelatin components of the gelatin mixture comprising 10-90 wt. % high-bloom gelatin having a gel strength of≧250 bloom and 90-10 wt. % medium-bloom gelatin having a gel strength of≧50 to<250 bloom, the specifications in wt. % relating to the total weight of the gelatin components of the gelatin mixture. | 09-22-2011 |
20110244016 | MEDICAL IMPLANT HAVING A COATING COMPOSED OF OR CONTAINING AT LEAST ONE ACTIVE SUBSTANCE - One embodiment of the invention relates to a medical implant whose surface is completely or partially covered by a coating composed of at least one active substance or containing at least one active substance. | 10-06-2011 |
20110276124 | BIOCORRODABLE IMPLANT IN WHICH CORROSION MAY BE TRIGGERED OR ACCELERATED AFTER IMPLANTATION BY MEANS OF AN EXTERNAL STIMULUS - The present invention relates to a biocorrodable implant in which corrosion may be triggered or accelerated after implantation by means of an external stimulus, the implant having a base body which is completely or partially composed of a biocorrodable metallic material, and the base body having a coating with a protective layer which is not biocorrodable. According to the invention, the implant has control elements which are configured in such a way that the protective layer, optionally in combination with the control elements, completely or partially encloses the base body so as to be impermeable to bodily medium, and the protective layer being to convertible to a form which is permeable to bodily medium as the result of a change in shape of the control elements which may be regulated and/or controlled by an external stimulus. | 11-10-2011 |
20110307054 | IMPLANT COATING WITH NUCLEIC ACIDS - One example embodiment of the present invention relates to an implant with a coating or a cavity filling containing a nucleic acid, which i) can inhibit the expression of at least one representative of the Ras gene family by means of RNA interference; or ii) encodes for a nucleic acid that can inhibit the expression of at least one representative of the Ras gene family by means of RNA interference. | 12-15-2011 |
20120016466 | ABLUMINALLY COATED DRUG-ELUTING STENTS HAVING A FORM-FITTING PROTECTIVE LAYER - A drug-eluting stent, comprising a base body that is made of an implant material, the base body being partially or entirely covered on the abluminal side with an active ingredient-releasing coating that comprises or is made of a polymer and an active ingredient having an antiproliferative effect, characterized in that the stent's luminal surface and the abluminal surface carrying the active ingredient-releasing coating are covered by a biocorrodible protective layer in a form-fitting manner. | 01-19-2012 |
20120035716 | POLYLACTIDE-COATED IMPLANT COMPOSED OF A BIOCORRODIBLE MAGNESIUM ALLOY - Some invention embodiments relate to an implant having a base body composed of a biocorrodible magnesium alloy and a polylactide coating. The implant is characterized in that the coating contains seed crystals and/or lipophilic substances as additives. | 02-09-2012 |
20120078349 | COATED IMPLANT COMPOSED OF A BIOCORRODIBLE MAGNESIUM ALLOY - One embodiment of the invention relates to a coated implant having a base body composed of a biocorrodible magnesium alloy. The coating of the implant comprises: | 03-29-2012 |
20120121658 | FUNCTIONALIZED RGD PEPTIDOMIMETICS AND THEIR MANUFACTURE, AND IMPLANT HAVING A COATING CONTAINING SUCH FUNCTIONALIZED RGD PEPTIDOMIMETICS - At least some embodiments of the invention relates to an implant having a coating that contains or is composed of a functionalized RGD peptidomimetic RGD-P1 having the formula (1) and/or a functionalized RGD peptidomimetic RGD-P2 having the formula (2), and an associated manufacturing method. | 05-17-2012 |
20120121659 | FUNCTIONALIZED RGD PEPTIDOMIMETICS AND THEIR MANUFACTURE, AND IMPLANT HAVING A COATING CONTAINING SUCH FUNCTIONALIZED RGD PEPTIDOMIMETICS - At least some embodiments of the invention relates to an implant having a coating that contains or is composed of a functionalized RGD peptidomimetic RGD-P1 having the formula (1) and/or a functionalized RGD peptidomimetic RGD-P2 having the formula (2), and an associated manufacturing method. | 05-17-2012 |
20120121682 | cRGD PEPTIDE DERIVATIVE AND ITS MANUFACTURE, AND IMPLANT HAVING A COATING CONTAINING A cRGD PEPTIDE DERIVATIVE - Various embodiments of the invention relate to a cRGD peptide derivative and an associated manufacturing method, and to an implant having a coating containing a cRGD peptide derivative. One aspect of the invention is the provision of a cRGD peptide derivative having the formula (1): | 05-17-2012 |
20120123235 | IMPLANTABLE THERANOSTIC ARTICLE - A theranostic article has one or more specific molecular recognition markers for cells on the surface thereof, wherein the recognition markers are selected from the group consisting of peptides, proteins, antibodies, antigens, aptamers, molecular imprinted polymers and polynucleotides. When the article is implanted in a body, cellular ingrowth is controlled, with desired cell types anchoring and proliferating on the implant's surface to generate a thin layer, and thereafter ceasing accumulation. The cellular layer thereby presents a biomimetic surface acceptable to the body, and also presents a low barrier to diffusion of analytes with at least substantially constant diffusion characteristics, allowing use of an analyte sensor within the article. | 05-17-2012 |
20120150284 | IMPLANT COMPRISING AN ACTIVE-AGENT-CONTAINING COATING COVERING THE IMPLANT AT LEAST IN SECTIONS - The invention relates to an implant comprising an active-agent-containing coating which covers the implant at least in sections. The coating is composed of at least two subsections; a first subsection contains the at least one active substance, and a second subsection contains an auxiliary agent. | 06-14-2012 |
20120158123 | POLYMER STENT - The invention relates to a stent, comprising or consisting of amorphous polylactide. The invention relates further to the use of amorphous polylactide for stabilizing a stent and a method for producing a corresponding stent. | 06-21-2012 |
20120158126 | IMPLANT AND METHOD FOR PRODUCING THE SAME - The present invention relates to an implant ( | 06-21-2012 |
20120191183 | MEDICAL VALVE IMPLANT, IN PARTICULAR HEART VALVE IMPLANT, FOR IMPLANTATION IN AN ANIMAL BODY AND/OR HUMAN BODY - The invention relates to a medical valve implant ( | 07-26-2012 |
20120203331 | IMPLANTATION DEVICE - The invention relates to an implantation device ( | 08-09-2012 |
20120221099 | COATED BIOLOGICAL MATERIAL HAVING IMPROVED PROPERTIES - Some embodiments of the present invention relate to coated biological material for the manufacture of heart valve prostheses, characterized in that the surface of the biological material is covered entirely or partially with a coating which contains or is composed of a biocompatible anorganic material, and to a process for manufacturing such a coated biological material. | 08-30-2012 |
20140094898 | BIOPROSTHETIC COMPONENTS FOR AN IMPLANT, IN PARTICULAR PARTLY CROSSLINKED BIOLOGICAL HEART VALVES - Bioprosthetic components based on, or comprising, biological materials for implants, preferably biological heart valves, in particular biological heart valve leaflets, which have only been chemically or thermally stabilized (partly crosslinked) at mechanically stressed points and therefore have zones having different mechanical properties, and to a method for the production thereof. | 04-03-2014 |
20140222134 | FUNCTIONALIZED RGD PEPTIDOMIMETICS AND THEIR MANUFACTURE, AND IMPLANT HAVING A COATING CONTAINING SUCH FUNCTIONAL-IZED RGD PEPTIDOMIMETICS - At least some embodiments of the invention relates to an implant having a coating that contains or is composed of a functionalized RGD peptidomimetic RGD-P1 having the formula (1) and/or a functionalized RGD peptidomimetic RGD-P2 having the formula (2), and an associated manufacturing method. | 08-07-2014 |