Nardini
Claudia Nardini, Lucca IT
Patent application number | Description | Published |
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20110282032 | PROCESS FOR HIGHLY SELECTIVE PURIFICATION OF TWO PLASMA PROTEINS: VON WILLEBRAND FACTOR (VWF) AND FIBRONECTIN (FN) - There is described a chromatographic purification process that allows highly purified von Willebrand factor (vWF) and Fibronectin (Fn) to be obtained, starting from a biological fraction enriched in vWF and Fn and easily scaled up to industrial level. Chromatographic purification was obtained by a strong anionic exchange resin. The concentrates obtained have a high specific activity and, given the low content of contaminant proteins, are particularly suitable for therapeutic use. | 11-17-2011 |
20120316323 | NEW PROCESS FOR THE INDUSTRIAL-SCALE PURIFICATION OF GAMMA GLOBULINS FROM HUMAN PLASMA FOR INDUSTRIAL APPLICATIONS - The invention relates to a novel, industrial-scale process for the purification of gamma-immunoglobulins (IgG) starting from plasma or fractions thereof. The method involves two chromatographic steps, i.e. a cation exchange capture chromatography, and then a polishing anion exchange chromatography, ensuring a highly purified end product, which contains no aggregates, and high yields. The process also involves a virus inactivation step by means of a solvent/detergent treatment to inactivate the viruses with a lipid envelope, and a virus removal step by nanofiltering to ensure the removal of the non-enveloped viruses. | 12-13-2012 |
Douglas Nardini, Pueblo, CO US
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20160045796 | Cleaning Device - A golf equipment cleaning device is provided wherein the cleaning device selectively expels a pressurized fluid that a golfer may use at any point on the golf course. A golfer may use a hand pump to pressurize a container that comprises a fluid. Then, the golfer may release the pressurized fluid through the end of a bristled brush such that the golfer may scrub a golf ball or golf club with a bristled brush and a pressurized fluid. | 02-18-2016 |
Dubravko Nardini, Oxford GB
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20090100892 | Method and apparatus for producing untrimmed container bodies - Exemplary embodiments of the invention relate to an apparatus and method for producing untrimmed container bodies from pre-cut metal blanks. The method involves cupping a pre-cut metal blank by positioning the blank against an immovable draw punch comprising an annular body having an inner surface adapted to form a redraw die and an outer surface, and drawing a periphery of the blank over the outer surface of the draw punch with an encircling draw die to form a cup having an open end, a closed end and an interior. The cup is then inverted and redrawn by forcing a redraw punch into the closed end of the cup to draw the closed end through the redraw die until the cup is inverted to form an inverted cup with a closed end supported on the punch. The inverted cup while supported on the redraw punch is passed through one or more ironing rings to lengthen the inverted cup to form an untrimmed container body having a closed end. The closed end of the untrimmed container body is shaped by engaging the closed end of the untrimmed container body with one or more end shaping tools while supported on the redraw punch. The apparatus comprises tools, actuators and a solid support structure adapted to carry out the method. | 04-23-2009 |
20100242567 | Method and apparatus for producing untrimmed container bodies - Exemplary embodiments of the invention relate to an apparatus and method for producing untrimmed container bodies from pre-cut metal blanks. The method involves cupping a metal blank by positioning the blank against an immovable draw punch comprising an annular body having an inner surface adapted to form a redraw die and an outer surface, and drawing a periphery of the blank over the outer surface of the draw punch with an encircling draw die to form a cup having an open end, a closed end and an interior. The cup is then inverted and redrawn by forcing a redraw punch into the closed end of the cup to draw the closed end through the redraw die until the cup is inverted to form an inverted cup with a closed end supported on the punch. The inverted cup while supported on the redraw punch is passed through one or more ironing rings to lengthen the inverted cup to form an untrimmed container body having a closed end. The closed end of the untrimmed container body is shaped by engaging the closed end of the untrimmed container body with one or more end shaping tools while supported on the redraw punch. The apparatus comprises tools, actuators and a solid support structure adapted to carry out the method. The metal blank may be pre-cut and supplied to the apparatus for shaping, or it may be cut from a metal sheet supplied to the equipment just as the shaping operations commence. | 09-30-2010 |
Giovanni Nardini, Pisa IT
Patent application number | Description | Published |
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20160113028 | METHOD FOR SCHEDULING RADIO RESOURCES - A method for allocating resource blocks of a transmission frame on a cellular network. The cellular network includes a cluster of antennas and a master unit of the cluster. Each antenna of each cluster is configured to provide radio coverage over a corresponding cell to exchange data with corresponding user equipment in communication with the antenna. During the transmission frame the antennas of the cluster are configured to be selectively activated and muted according to a plurality of cluster muting conditions. | 04-21-2016 |
Ilaria Nardini, Barga IT
Patent application number | Description | Published |
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20110282032 | PROCESS FOR HIGHLY SELECTIVE PURIFICATION OF TWO PLASMA PROTEINS: VON WILLEBRAND FACTOR (VWF) AND FIBRONECTIN (FN) - There is described a chromatographic purification process that allows highly purified von Willebrand factor (vWF) and Fibronectin (Fn) to be obtained, starting from a biological fraction enriched in vWF and Fn and easily scaled up to industrial level. Chromatographic purification was obtained by a strong anionic exchange resin. The concentrates obtained have a high specific activity and, given the low content of contaminant proteins, are particularly suitable for therapeutic use. | 11-17-2011 |
20140039160 | NOVEL PROCESS FOR THE PREPARATION OF A VIRUS-INACTIVATED FV CONCENTRATE STARTING FROM HUMAN PLASMA, SCALABLE TO INDUSTRIAL LEVEL - The present invention provides a process for purifying FV starting from human plasma or a fractionation intermediate thereof, that is simple, scalable to the industrial level and relatively inexpensive compared to the methods described in the literature to date. The invention consists of the use of two anion exchange chromatography steps, the first of which has the purpose of separating the FV from the PTC component factors, while the second has the purpose of isolating the protein of interest from the majority of plasma proteins by means of selective interaction with the weak anion exchange support used. The process developed has also had a viral inactivation step and a viral removal step included, contributing to the safety of the final product obtained, without however significantly altering the process total recovery of FV, and without necessitating the introduction of additional steps for eliminating the inactivating agents used, thanks to the order in which the various steps are conducted. The process described in the present invention also enables an FV concentrate to be obtained that is stable once frozen at −20° C. | 02-06-2014 |
Lewis Nardini, Richardson, TX US
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20120084575 | Synchronized Voltage Scaling and Device Calibration - A method is provided for scaling voltage in an integrated circuit. A calibration operation is performed on a functional module on the integrated circuit periodically at a rate T1. At least one parameter on the integrated circuit in monitored to determine when a performance threshold is reached. A change is initiated to an operating voltage for a portion of the integrated circuit in response to reaching the threshold. The rate of performing calibration operation is increased to a higher rate T2 for a window of time W in response to initiating the change in operating voltage, after which the rate of performing calibration is returned to the rate T1. | 04-05-2012 |
20150067426 | PACKET BASED INTEGRATED CIRCUIT TESTING - Apparatus and method for testing an integrated circuit. An integrated circuit includes circuitry to be tested, scan chain logic, and a test adapter. The scan chain logic is configured to transfer test data to and test results from the circuitry. The test adapter is configured to extract the test data from a packet received from an automated test control system and to transfer the test data to the scan chain logic. The test adapter is also configured to receive the test results from the scan chain logic, and to packetize the test result for transmission to the automated test control system. | 03-05-2015 |
Massimo Nardini, Milano IT
Patent application number | Description | Published |
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20100222077 | METHOD FRO COMPUTING THE GEOGRAPHICAL LOCATION OF A MOBILE TERMINAL - The invention relates to a method for computing the geographical location of a mobile terminal (MT) in a cellular telecommunications network. The method includes the steps of collecting identifiers of possible serving cells for the mobile terminal, selecting from a first database (A) geographical coordinates (LONG, LAT) whose expected serving cell ID matches any one of the identifiers of possible serving cells, comparing, for each selected geographical coordinate (LONG, LAT), pairs of cell identifiers and corresponding expected received signal values associated with the geographical coordinate (LONG, LAT) in the first database (A) with pairs of cell identifiers and corresponding actual received signal values of the possible serving cells to determine the geographical locations (LONG, LAT) having a number of matches (NMATCH) greater than a predetermined match threshold (THRESHOLD-NMATCH) and finally processing the geographical locations so determined (LONG, LAT) to obtain the geographical location of the mobile terminal (MT). | 09-02-2010 |
Maurizio Nardini, Pocenia IT
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20130000341 | HEAT EXCHANGER FOR A REFRIGERATED AIR DRYER - A refrigerated air dryer includes a three-path heat exchanger | 01-03-2013 |
Mauro Luciano Nardini, Buenos Aires AR
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20110319802 | FOOT CORRECTION DEVICE - A foot correction device to aid and improve the step pressure points in a humans foot, wherein the device comprises a first element containing a plurality of separating means, wherein said first element is connected to a second element comprising fixing and adjusting means of said foot correction device to the user's foot, having said second element a plurality of backing supplements. A method to reeducate the global posture of a human's foot using a foot correction device, the method comprises the steps of inserting the toes between the gaps defined in the separating means; sliding the device until the separating means tops with the toe's joints; adjusting the separating means using the adjustable means; proceeding with the adjustment by means of the fixing and adjusting means of the second element and optionally performing several specific routines | 12-29-2011 |
20120197171 | FOOT CORRECTION DEVICE - A foot correction device to aid and improve the step pressure points in a humans foot, wherein the device comprises a first element containing a plurality of separating means, wherein said first element is connected to a second element comprising fixing and adjusting means of said foot correction device to the user's foot, having said second element a plurality of backing supplements. A method to reeducate the global posture of a human's foot using a foot correction device, the method comprises the steps of inserting the toes between the gaps defined in the separating means; sliding the device until the separating means tops with the toe's joints; adjusting the separating means using the adjustable means; proceeding with the adjustment by means of the fixing and adjusting means of the second element and optionally performing several specific routines | 08-02-2012 |
Paquale Nardini, Villa Collemandina (lu) IT
Patent application number | Description | Published |
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20120220945 | INFUSION KIT WITH A RETRACTABLE NEEDLE - Infusion kit includes: a butterfly needle having a stiff rod-shaped body, at least a pair of coplanar wings laterally and outwardly extending therefrom; a cavity for receiving a slide, supporting a sliding needle from which an element projects and engages a straight groove along the body; the element being longer than the cavity and projecting from the body, is insertable in a housing connected to the groove to compressibly block a spring between the slide and the cavity bottom wall; an infusion cannula including a central and hollow cylinder, a flexible element, at least a coupling having an inner passage; the flexible element and the passage communicating via the cavity to allow draining a fluid or the supply from the outside; the flexible element is hollow and allows insertion of the needle of the butterfly needle through the cavity; at least a pair of coplanar wings extend from the cylinder. | 08-30-2012 |
Reto Nardini, Grenchen CH
Patent application number | Description | Published |
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20110054476 | Stabilizing Bone Fixation Element - A bone fixation device includes (a) a threaded shaft extending from a proximal end to a distal end; (b) a head located at the proximal end of the shaft; (c) a connector threadably engaging the threaded shaft and movable therealong; and (d) an extension member movable between an insertion configuration for insertion through an opening in a cortex of a bone to a locked configuration when pressed against an inner surface of the cortex. The profile of the wing in the locked configuration in the plane perpendicular to the longitudinal axis of the shaft is increased relative to the insertion configuration to distribute forces transmitted between the bone fixation apparatus and the bone over an increased area of the cortex. | 03-03-2011 |
20150094779 | CABLE TIE L-PIN - A device for treating a bone includes (a) an elongate body sized and shaped for insertion into a bone and extending longitudinally from a proximal end to a distal end, the elongate body including a channel extending therethrough and a coating along an outer surface thereof, the coating adapted to absorb a selected frequency of light such that, when the selected frequency of light is applied thereto, portions of the coating melt to form a mass; and (b) a first anchor member slidably mountable over the elongate body and movable therealong from a first position at the proximal end of the elongate body to a second position adjacent a bone into which the elongate body has been inserted to cooperate with the mass to fix the elongate body to the bone. | 04-02-2015 |
20150223855 | BONE FIXATION SYSTEM - A bone fixation system is provided. The bone fixation system may include a plate, one or more fasteners configured to attach the plate to a target anatomical location such as bone, and a surgical device that facilitates the attachment of the plate and the fasteners. | 08-13-2015 |
20150352784 | Integrated Multi-Material Implants and Methods of Manufacture - Provided are methods and systems for fabricating multimaterial bodies in a layer-wise fashion, which bodies may be used bone-stabilizing implants. The multimaterial bodies include rigid and flexible portions that are integrally formed with one another. The multimaterial bodies may be softened or stiffened in specific areas to match the biological or anatomical features of a bone. | 12-10-2015 |
20160100877 | BONE FIXATION SYSTEM - A bone fixation system is provided. The bone fixation system may include a plate, one or more fasteners configured to attach the plate to a target anatomical location such as bone, and a surgical device that facilitates the attachment of the plate and the fasteners. | 04-14-2016 |
Reto Nardini, Oberdorf CH
Patent application number | Description | Published |
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20110190904 | INTEGRATED MULTI-MATERIAL IMPLANTS AND METHODS OF MANUFACTURE - Provided are methods and systems for fabricating multimaterial bodies in a layer-wise fashion, which bodies may be used bone-stabilizing implants. The multimaterial bodies include rigid and flexible portions that are integrally formed with one another. The multimaterial bodies may be softened or stiffened in specific areas to match the biological or anatomical features of a bone. | 08-04-2011 |
20130053968 | Patient Specific Joint Prosthesis - A patient-specific implant includes (a) a body having a convex exterior surface configured to attach to a bone and a concave interior surface configured to receive a head portion of another bone, the body including a plurality of holes extending therethrough, the holes sized and shaped to receive a bone fixation element; and (b) a gap filler formed on the exterior surface of the body and having dimensions and a position corresponding to a gap between the exterior surface of the body and the bone to which the implant is to be attached. | 02-28-2013 |
20130060290 | Cable Tie L-Pin - A device for treating a bone includes (a) an elongate body sized and shaped for insertion into a bone and extending longitudinally from a proximal end to a distal end, the elongate body including a channel extending therethrough and a coating along an outer surface thereof, the coating adapted to absorb a selected frequency of light such that, when the selected frequency of light is applied thereto, portions of the coating melt to form a mass; and (b) a first anchor member slidably mountable over the elongate body and movable therealong from a first position at the proximal end of the elongate body to a second position adjacent a bone into which the elongate body has been inserted to cooperate with the mass to fix the elongate body to the bone. | 03-07-2013 |
20130158553 | Self Centering Feature for an Intramedullary Nail - An intramedullary nail includes a body sized and shaped for insertion into a medullary canal of a bone and extending along a longitudinal axis from a proximal end to a distal end and a channel extending through the body along the longitudinal axis in combination with a locking hole extending laterally through the body along a central axis and in communication with the channel, the locking hole defined by a first opening extending through a first portion of a wall of the nail and a second opening extending through a second portion of the wall substantially opposing the first portion, the first opening being elongated in a lateral direction relative to the longitudinal axis of the nail and the second opening including a coupling element configured to lock a portion of a bone fixation element therein. | 06-20-2013 |
20140074252 | EXPANDABLE IMPLANT - An implant system includes a fixation device that, in turn can include an expandable implant alone or in combination with an auxiliary implant. The expandable implant includes an expandable implant body that is made from an expandable material. The expandable material includes a polymer matrix and an expandable gas source contained within at least a portion of the polymer matrix. The implant system can further include an energy source configured to heat the polymer matrix to a temperature above its glass transition temperature, thereby causing the gas source to expand inside the polymer matrix. The fixation device can further include an insertion instrument configured to implant the fixation device into an anatomical cavity. | 03-13-2014 |
Reto Nardini, Langendorf CH
Patent application number | Description | Published |
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20110160870 | EXPANDABLE IMPLANT - An implant system includes a fixation device that, in turn can include an expandable implant alone or in combination with an auxiliary implant. The expandable implant includes an expandable implant body that is made from an expandable material. The expandable material includes a polymer matrix and an expandable gas source contained within at least a portion of the polymer matrix. The implant system can further include an energy source configured to heat the polymer matrix to a temperature above its glass transition temperature, thereby causing the gas source to expand inside the polymer matrix. The fixation device can further include an insertion instrument configured to implant the fixation device into an anatomical cavity. | 06-30-2011 |
20110245819 | BONE FIXATION SYSTEM - A bone fixation system is provided. The bone fixation system may include a plate, one or more fasteners configured to attach the plate to a target anatomical location such as bone, and a surgical device that facilitates the attachment of the plate and the fasteners. | 10-06-2011 |
20120226278 | Intramedullary Nail - An intramedullary nail extending from a proximal end to a distal end comprises a distal portion extending longitudinally from the distal end to a first connecting end and including a first locking hole extending therethrough; a proximal end extending longitudinally from a second connecting end to the proximal end of the nail and including a second locking hole extending transversely therethrough and a joint connecting the first and second connecting ends such that the distal and proximal portions are rotatable relative to one another about the joint. | 09-06-2012 |
20120239039 | Device for Measuring the Degree of Bending of an Intramedullary Nail - A device for measuring a degree of bending of an intramedullary nail comprises a probe sized and shaped for insertion into a cannulation of an intramedullary nail. The probe including a first longitudinal element extending along a longitudinal axis from a distal end to a proximal end and a second longitudinal element extending along a longitudinal axis from a distal end to a proximal end, the distal ends of the first and second longitudinal elements attached to one another so that the longitudinal axes of the first and second longitudinal elements extend substantially parallel to each other and define a middle plane. A measuring element measures relative axial displacement of the proximal ends of the first and second longitudinal elements in the middle plane upon bending of the first and second longitudinal elements as the probe is inserted into a cannulation of the intramedullary nail. | 09-20-2012 |
20130150851 | MONOFIX NAIL - An intramedullary device includes an intramedullary nail extending along a longitudinal axis from a proximal end to a distal end, the nail including a channel extending longitudinally therethrough and an opening extending laterally through a wall thereof proximate the distal end, the channel including a ramped surface along a distal portion thereof opposite the opening. The device further includes a wire extending along a longitudinal axis from a proximal end to a distal end, the wire sized and shaped to be inserted into the channel of the nail such that the distal end engages the ramped surface to extend through the opening. | 06-13-2013 |
20130211405 | SUTURE DISTAL LOCKING - A system for locking an intramedullary nail to a bone includes a first plate sized and shaped to be inserted through a channel of an intramedullary nail and dimensioned to prevent its passing through a locking hole of the intramedullary nail and a second plate sized and shaped to be positioned along a portion of an exterior of a hole drilled in the bone and dimensioned to prevent its passing through the hole drilled in the bone along with a connector couplable to the first and second plates and slidable through the channel of the intramedullary nail to extend through the locking hole from an interior of the channel to an exterior of a bone in which the intramedullary nail has been inserted. | 08-15-2013 |
20140336651 | SUTURE DISTAL LOCKING - A system for locking an intramedullary nail to a bone includes a first plate sized and shaped to be inserted through a channel of an intramedullary nail and dimensioned to prevent its passing through a locking hole of the intramedullary nail and a second plate sized and shaped to be positioned along a portion of an exterior of a hole drilled in the bone and dimensioned to prevent its passing through the hole drilled in the bone along with a connector couplable to the first and second plates and slidable through the channel of the intramedullary nail to extend through the locking hole from an interior of the channel to an exterior of a bone in which the intramedullary nail has been inserted. | 11-13-2014 |
Thomas Anthony Nardini, Portland, OR US
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20150055769 | Method for Improving Connection Success in Arranging Video Chat among Candidate Conversants - A system registers participant information and inter-participant relationship information, and then, at variable times, selects two or more participants with a pre-existing relationship and attempts to establish a communication link between them. At least one of the participants is notified that the communication link will be attempted, shortly before the attempt is made. The identities of the selected participants are withheld from at least one of the participants (and potentially from all of the participants), so the call is a partial surprise (i.e., the participant may know the set of possible people from whom the call could be, but does not know exactly which person or people are calling until he answers the call). A number of applications are described and claimed. | 02-26-2015 |