Patent application number | Description | Published |
20090318848 | MEDICAL DEVICES EMPLOYING CONDUCTIVE POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS - In accordance with one aspect, the invention relates to medical devices which comprise at least one reservoir, a therapeutic-agent-containing region disposed within the reservoir and an electrode comprising a conductive polymer. The devices of the invention are configured such that a rate of release of the therapeutic agent from the reservoir changes upon a change in the oxidation state of the conductive polymer. | 12-24-2009 |
20090324684 | MEDICAL DEVICES HAVING SURFACE COATINGS - According to an aspect of the present invention, medical devices are provided which comprise a metallic region and a coating on all or part of the metallic region that comprises a multivalent acid. | 12-31-2009 |
20100222873 | Self-Buffering Medical Implants - A medical implant includes a bioerodible portion that includes a bioerodible polymer and a bioerodible metal. The bioerodible polymer matrix degrades under physiological conditions to form acidic degradation products. The bioerodible metal degrades under physiological conditions to form basic degradation products. The acidic degradation products and the basic degradation products buffer at least a portion of the medical implant. In one aspect, the bioerodible portion includes a bioerodible polymer matrix and a bioerodible metal within the bioerodible polymer matrix. In another aspect, the medical implant can include a body, a plurality of discrete deposits of the bioerodible polymer on the body, and a plurality of discrete deposits of the bioerodible metal on the body. | 09-02-2010 |
20110245905 | ENDOPROSTHESIS - Among other things, a bio-erodible implantable endoprosthesis comprises a member that includes (a) a core having a surface, and (b) a bio-erodible metal on a least a portion of the surface of the core, wherein the bio-erodible metal erodes more slowly than the core and includes openings through which physiological fluids can access the core upon implantation. | 10-06-2011 |
20120197380 | Medical Devices and Related Methods - This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon. | 08-02-2012 |
20140207061 | Medical Devices and Related Methods - This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon. | 07-24-2014 |
Patent application number | Description | Published |
20090118815 | STENT - Endoprosthesis includes coatings of selected porosity formed of particulates of ceramics, metals, drugs and/or polymers. | 05-07-2009 |
20100008970 | Drug-Eluting Endoprosthesis - A drug-eluting endoprosthesis that includes a bioerodible metal portion and a therapeutic agent. In some aspects, the endoprosthesis includes a plurality of discrete deposits and a plurality of overlying layers each overlying one of the plurality of discrete deposits. Each discrete deposit includes one or more therapeutic agents and each overlying layer includes one or more bioerodible metals. In other aspects, the bioerodible metal portion includes at least two bioerodible metal regions having different electronegativities. The at least two bioerodible metal regions being in electrical contact with each other. The bioerodible metal erodes in a physiological environment to release the therapeutic agent. | 01-14-2010 |
20110238153 | ENDOPROSTHESES - Endoprostheses include an endoprosthesis wall that includes a surface layer that includes a metallic material and that defines a plurality of discrete pores. A porous material is disposed in one or more pores of the surface layer. The endoprostheses can, for example, deliver a therapeutic agent, such as a drug, in a controlled manner over an extended period of time. | 09-29-2011 |
Patent application number | Description | Published |
20090099634 | CONDUCTIVE COMPOSITE ELECTRODE MATERIAL - A medical electrical lead and body implantable electrode suitable for a variety of medical applications are disclosed. In general, the electrode includes a composite material having particles of pseudo-capacitive material, such as iridium oxide, dispersed within a polymer matrix including a polyelectrolyte. The polymer matrix can also include a conductive polymer doped with an excess of the polyelectrolyte. The composite may used to form the electrode itself or an electrode coating. The presence of a pseudo-capacitive material within the composite may increase the charge-storage capacity of the electrode and may allow for safe deliveries of charge densities within an electrochemical window suitable for pacing a patient's heart. | 04-16-2009 |
20090105796 | FIBROUS ELECTRODE MATERIAL - A biomimetic electrode material including a fibrous matrix including a conductive polymer and an ion conducting polymeric material is described. The biomimetic electrode material may be used in a number of body-implantable application including cardiac and neuro-stimulation applications. The biomimetic electrode material can be formed using electrospinning and other related processes. The biomimetic electrode may facilitate efficient charge transport from ionically conductive tissue to the electronically conductive electrode and may induce surrounding tissue to attach or interface directly to the implanted device, increasing the biocompatibility of the device. | 04-23-2009 |
20110112617 | CONDUCTIVE COMPOSITE ELECTRODE MATERIAL - A medical electrical lead and body implantable electrode suitable for a variety of medical applications are disclosed. In general, the electrode includes a composite material having particles of pseudo-capacitive material, such as iridium oxide, dispersed within a polymer matrix including a polyelectrolyte. The polymer matrix can also include a conductive polymer doped with an excess of the polyelectrolyte. The composite may used to form the electrode itself or an electrode coating. The presence of a pseudo-capacitive material within the composite may increase the charge-storage capacity of the electrode and may allow for safe deliveries of charge densities within an electrochemical window suitable for pacing a patient's heart. | 05-12-2011 |
20110137389 | FIBROUS ELECTRODE MATERIAL - A biomimetic electrode material including a fibrous matrix including a conductive polymer and an ion conducting polymeric material is described. The biomimetic electrode material may be used in a number of body-implantable applications including cardiac and neuro-stimulation applications. The biomimetic electrode material can be formed using electrospinning and other related processes. The biomimetic electrode may facilitate efficient charge transport from ionically conductive tissue to the electronically conductive electrode, and may induce surrounding tissue to attach or interface directly to the implanted device, increasing the biocompatibility of the device. | 06-09-2011 |