Patent application number | Description | Published |
20100197512 | Multi-Sample Particle Analyzer and Method for High Throughput Screening - Embodiments of the present invention provide a system and method for analyzing a plurality of samples comprising obtaining with an autosampler a plurality of samples from a first plate having a plurality of sample wells wherein the autosampler has a plurality of probes for sampling a set of samples and wherein each probe of the plurality of probes is in communication with a separate flow cytometer via a separate conduit. The plurality of samples comprising particles is moved into a fluid flow stream for each separate conduit. Adjacent ones of the plurality of samples are separated from each other in the fluid flow stream by a separation gas, thereby forming a gas-separated fluid flow stream. The gas-separated fluid flow stream is independently guided to and through each separate flow cytometer. | 08-05-2010 |
20120061584 | System and Method for Separating Samples in a Continuous Flow - One embodiment of the present invention provides for a method for identifying within a single record the location of each of a plurality of samples suspected of containing particles of interest wherein the single record is obtained from a flowing stream of the plurality of samples passing through a particle analyzer. The method comprises introducing into a conduit the plurality of samples suspected of containing particles of interest wherein each ones of the plurality of samples are separated by fluid gaps to produce a plurality of samples separated by fluid gaps and wherein each of the plurality of samples further comprises marker particles. The plurality of samples separated by fluid gaps are flowed through the conduit as a flowing sample stream to a detector of a particle analyzer, which may be a flow cytometer. The particles of interest are detected as the samples pass the detector of the particle analyzer. | 03-15-2012 |
20120309635 | Multi-Sample Particle Analyzer and Method for High Throughput Screening - Embodiments of the present invention provide a system and method for analyzing a plurality of samples comprising obtaining with an autosampler a plurality of samples from a first plate having a plurality of sample wells wherein the autosampler has a plurality of probes for sampling a set of samples and wherein each probe of the plurality of probes is in communication with a separate flow cytometer via a separate conduit. The plurality of samples comprising particles is moved into a fluid flow stream for each separate conduit. Adjacent ones of the plurality of samples are separated from each other in the fluid flow stream by a separation gas, thereby forming a gas-separated fluid flow stream. The gas-separated fluid flow stream is independently guided to and through each separate flow cytometer. | 12-06-2012 |
20140152987 | System and Method for Separating Samples in a Continuous Flow - One embodiment of the present invention provides for a method for identifying within a single record the location of each of a plurality of samples suspected of containing particles of interest wherein the single record is obtained from a flowing stream of the plurality of samples passing through a particle analyzer. The method comprises introducing into a conduit the plurality of samples suspected of containing particles of interest wherein each ones of the plurality of samples are separated by fluid gaps to produce a plurality of samples separated by fluid gaps and wherein each of the plurality of samples further comprises marker particles. The plurality of samples separated by fluid gaps are flowed through the conduit as a flowing sample stream to a detector of a particle analyzer. The particle analyzer is for example a flow cytometer. The particles of interest when present and/or marker particles are detected as the plurality of samples pass the detector of the particle analyzer. A record over time for the particles of interest when present and/or marker particles in each of the plurality of samples are obtained in the single file once the plurality of samples pass the incident beam of light of the particle analyzer. A time position in the record is identified where particles of interest within any one of the plurality of samples would be located if present based upon the detection of marker particles present within each combined sample from the flowing stream of the plurality of samples. | 06-05-2014 |
20150226658 | Multi-Sample Particle Analyzer System and Method for High Throughput Screening - Embodiments of the present invention provide a system and method for analyzing a plurality of samples comprising obtaining with an autosampler a plurality of samples from a first plate having a plurality of sample wells wherein the autosampler has a plurality of probes for sampling a set of samples and wherein each probe of the plurality of probes is in communication with a separate flow cytometer via a separate conduit. The plurality of samples comprising particles is moved into a fluid flow stream for each separate conduit. Adjacent ones of the plurality of samples are separated from each other in the fluid flow stream by a separation gas, thereby forming a gas-separated fluid flow stream. The gas-separated fluid flow stream is independently guided to and through each separate flow cytometer. | 08-13-2015 |
Patent application number | Description | Published |
20150022819 | FIBER OPTIC GYROSCOPE DEAD BAND ERROR SUPPRESSION - Embodiments described herein provide a method of modulating an input light beam of a fiber optic coil of an IFOG. The method includes intermittently jumping the phase step of a feedback signal to suppress dead band. Jumping the phase step includes: creating a jumped phase step during a first cycle of the IFOG, the jumped phase step having a whole value configured to cause a phase jump in the feedback signal and a fractional value corresponding to the fractional value from a phase step of a cycle immediately preceding the first cycle. Jumping the phase step also includes generating the feedback signal from a sum of the bias modulation value and the jumped phase step. | 01-22-2015 |
20150316380 | FIBER OPTIC GYROSCOPE DEAD BAND ERROR SUPPRESSION - Embodiments described herein provide for a method of modulating an input light beam of an interferometric fiber optic gyroscope (IFOG). The method includes intermittently jumping a phase step to suppress dead band. During a first cycle, a first cycle raw rate is stored and a feedback signal is generated based on a jumped phase step. During a second cycle, a second cycle raw rate is stored and a feedback signal is generated based on the jumped phase step. During a third cycle, a third cycle phase step is generated by accumulating the first cycle raw rate with a second cycle phase step, and a feedback signal is generated from the third cycle phase step. During a fourth cycle, a fourth cycle phase step is generated by accumulating the second cycle raw rate with the third cycle phase step, and a feedback signal is generated from the fourth cycle phase step. | 11-05-2015 |
20150316381 | FIBER OPTIC GYROSCOPE DEAD BAND ERROR SUPPRESSION - Embodiments described herein provide for a method of modulating an input light beam of an interferometric fiber optic gyroscope (IFOG). The method includes intermittently jumping a phase step to suppress dead band. If a bit flip was clocked into a digital to analog converter generating the feedback signal at the beginning of a cycle in which the jumped phase step is implemented, the method includes at least one of re-introducing a rate difference corresponding to the bit flip, altering the timing of the bit flip, or altering the timing of the generating a feedback signal based on the jumped phase step. | 11-05-2015 |
Patent application number | Description | Published |
20090289825 | SYSTEMS AND METHODS FOR SYNTHESIS OF A SIGNAL - Systems and methods synthesize a signal from the odd harmonic frequency components of an input signal. An exemplary embodiment synthesizes a first signal with a digital to analog converter (DAC), generates a second signal from the first signal, and filters a selected one of the odd harmonic frequency components through a band pass filter to produce an output signal. The first signal is defined by a first frequency. The second signal is defined by the first frequency and comprises a fundamental frequency component and plurality of odd harmonic frequency components. The output signal has a frequency substantially equal to the frequency of the selected odd harmonic frequency component. | 11-26-2009 |
20110013194 | ALTERNATE MODULATION SCHEME FOR AN INTERFEROMETRIC FIBER OPTIC GYROSCOPE - An Interferometric Fiber Optic Gyro (IFOG) device for high accuracy sensing. An example IFOG includes an integrated optics chip (IOC) and a modulation component that modulates one or more light signals passing thru the IOC according to a bias-modulation waveform. A glitch pattern experienced at front-end components of the IFOG includes frequency content that has approximately zero amplitude at predefined sense harmonics. Frequency content of the bias-modulation waveform is below a predefined threshold value at the predefined sense harmonics. | 01-20-2011 |
20110227771 | INEXPENSIVELY IMPROVING RESOLUTION AND REDUCING NOISE OF LOW-NOISE SIGNALS - Systems and methods for improving resolution of low-noise signals in an analog-to-digital conversion circuit. A simple, low cost pseudo-noise generating circuit is disclosed that, when connected to the signal conditioning circuitry of A/D conversion circuit, adds pseudo-noise to an analog input voltage signal. Additional pseudo-noise is beneficial for improving the resolution of analog-to-digital conversion when oversampling and summing or averaging are used in post-conversion processing operations. The circuit is composed of a plurality of resistors configured in at least two parallel branches. An individually switchable voltage source output is connected to each branch. A resulting analog voltage can be measured at a common termination point for the branches, depending on the combination of switchable voltage source output turned on, and the branch to which the voltage output is applied. By varying the combination of switchable voltage source outputs turned on over time, a known analog pseudo-noise signal is developed. | 09-22-2011 |