Patent application number | Description | Published |
20140144537 | WIRED PIPE COUPLER CONNECTOR - A method of forming a wired pipe transmission line includes: providing an assembly that includes an inner conductor surrounded by an insulating material; attaching a fixation element to the assembly at or near an end thereof; providing a tubular outer conductor; disposing the assembly and the fixation element within the outer conductor; and fixedly attaching the fixation element to the inner portion of the tubular outer conductor. | 05-29-2014 |
20140166309 | PRESSURE COMPENSATION DEVICE FOR THREAD CONNECTIONS - A threaded tubular section includes a first tubular member made of a first material, the first tubular member including a threaded pin section. The section also includes a second tubular member made of a second material, the second tubular member including a threaded box section to mate with the threaded pin section. A pressure equalization device made of a third material is disposed between the first tubular member and the second tubular member, the pressure equalization device including one or more openings to equalize pressure in an interior of a thread connection of the first and the second tubular members with pressure in a bore or an annulus of the first and the second tubular members. | 06-19-2014 |
20140176334 | ELECTRONIC FRAME FOR USE WITH COUPLED CONDUIT SEGMENTS - An electronic frame for use in a downhole component coupling mechanism includes: a first frame element including at least one retaining structure configured to retain an electronic component; and a second frame element configured to be disposed at the first frame element, the second frame element permanently joined to the first frame element to isolate the electronic component from downhole fluids and form the electronic frame, the electronic frame configured to be disposed in a coupling assembly of a first downhole component and a second downhole component and constrained axially by the coupling assembly. | 06-26-2014 |
20140209293 | DOWNHOLE ASSEMBLY - A downhole assembly includes a wave seal packer including a wave portion having a wave form shape in an un-expanded condition. The wave portion configured to radially encircle a tubular with alternating and interconnected uphole and downhole portions. The packer having a substantially uniform internal radius in the un-expanded condition. | 07-31-2014 |
20140209296 | TUBE LOCKING MECHANISM FOR DOWNHOLE COMPONENTS - An apparatus for securing a transmission line in a downhole component includes: an element coupled to an exterior surface of the transmission line, the transmission line configured to be disposed in a communication conduit that extends through the downhole component, the element configured to restrict axial movement of the transmission line within the communication conduit. | 07-31-2014 |
20140209324 | MAINTAINING TENSION OF A TRANSMISSION LINE IN A TUBULAR - An apparatus for maintaining tension of a transmission line in a tubular includes a first clamp segment configured to surround at least a portion of a transmission line and a second clamp segment configured to surround at least a portion of the transmission line. The second clamp segment has a first axial end and a second axial end. The first axial end is configured to contact an axial end of the first clamp segment, such that the first clamp segment and the second clamp segment are configured to apply a force in opposite radial directions to clamp the transmission line with respect to the tubular to lock a position of the transmission line with respect to the tubular. | 07-31-2014 |
20140332235 | COUPLED ELECTRONIC AND POWER SUPPLY FRAMES FOR USE WITH BOREHOLE CONDUIT CONNECTIONS - An apparatus for retaining electronic components in a downhole component coupling mechanism includes: a power supply frame including a first housing configured to retain a power supply therein and isolate the power supply from downhole fluids, the power supply frame configured to be disposed in and constrained axially by a coupling assembly of a first downhole component and a second downhole component; an electronic component disposed in a second housing in the coupling assembly, the electronic component located external to the power supply frame; and a connector configured to transmit electric power from the power supply to the electronic component to supply electrical power to the electronic component. | 11-13-2014 |
20140374167 | ELECTRONICS FRAME WITH SHAPE MEMORY SEAL ELEMENTS - An electronics frame for a wired pipe drill string, including a housing arranged to be disposed within the wired pipe drill string. The housing includes a chamber formed therein and one or more electronic components disposed in the chamber. A shape memory element is disposed in the chamber. The shape memory element is transitionable in response to a transition stimulus between a first shape permitting positioning within the chamber and a second shape sealingly engagable with the housing to isolate the one or more electronic components from fluid. A method of isolating an electronic component is also included. | 12-25-2014 |
20150027685 | SHOULDER RING FOR TRANSMISSION LINE AND TRANSMISSION DEVICES - A tubular section and a system including the tubular section are described. The tubular section includes a first tubular member including a threaded pin section and a second tubular member, the second tubular member including a threaded box section configured to mate with the threaded pin section. The tubular section also includes a shoulder ring disposed between the first tubular member and the second tubular member, wherein a wall thickness of at least a portion of the shoulder ring is greater than a smallest wall thickness of the threaded pin section of the first tubular member. | 01-29-2015 |
20150041214 | RETENTION DEVICE FOR DRILL PIPE TRANSMISSION LINE - An apparatus for communicating a signal to or from a downhole tool includes a drill pipe configured to be rotated to drill a borehole, a tubular under axial tension and secured in the drill pipe, and a retention device secured to the tubular and configured to maintain the tubular under the axial tension. The retention device includes a portion extending from a body of the device in a direction that is non-inward-radial with respect to a longitudinal axis of the drill pipe. The apparatus further includes a transmission line disposed in the tubular and in an opening of the retention device and in communication with the downhole tool. | 02-12-2015 |
20150060041 | ELECTRONIC FRAME FOR USE WITH COUPLED CONDUIT SEGMENTS - An electronic frame for use in a downhole component coupling mechanism in a segmented wired pipe system includes a first frame element including at least one retaining structure configured to retain an electronic component. The frame also includes a sealed chamber disposed in the frame element, the sealed chamber including inputs to receive input signals from communication elements and either couple the inputs together or direct the input signals to control electronics. | 03-05-2015 |
20150248950 | TRANSMISSION LINE FOR WIRED PIPE, AND METHOD - A wired pipe transmission line for disposal in a wired pipe segment for use in subterranean drilling. The transmission line includes an assembly including an inner conductor and a dielectric layer including silicon dioxide (SiO | 09-03-2015 |
20150337641 | DOWNHOLE TOOL INCLUDING A MULTI-CHIP MODULE HOUSING - A downhole tool includes a tool body having an in inner surface portion and an outer surface portion. The outer surface portion includes a recess having a peripheral wall and an inner surface. A multi-chip module (MCM) housing is defined in the recess. The MCM housing includes one or more fortifying members that support axial and radial loading of the downhole tool and include one or more electronics receiving zones. | 11-26-2015 |
20150337644 | REMOVEABLE ELECTRONIC COMPONENT ACCESS MEMBER FOR A DOWNHOLE SYSTEM - A downhole tool includes a tool body having an outer surface portion and an inner surface portion and a recess formed in one of the outer surface portion and inner surface portion. At least one removable electronic component access member is detachably mounted to the tool body. The removable electronic component access member provides access to electronic components housed in the recess. A metallic seal is provided on at least one of the tool body and the removable electronic component access member. The metallic seal prevents fluid ingress into the recess through the at least one removable electronic component access member. | 11-26-2015 |
20160076364 | TRANSMISSION LINE FOR DRILL PIPES AND DOWNHOLE TOOLS - A method of forming a wired pipe transmission line includes: providing an assembly that includes an inner conductor surrounded by an insulating material; attaching a fixation element to the assembly at or near an end thereof; providing a tubular outer conductor; disposing the assembly and the fixation element within the outer conductor; and fixedly attaching the fixation element to the inner portion of the tubular outer conductor. | 03-17-2016 |
Patent application number | Description | Published |
20080202070 | Culling method for blister-pack production line - A continuous and elongated blister-pack strip having transverse rows of blisters of which some are empty and most are full is transported through a stamping station. Upstream of the stamping station whether any blisters entering the stamping station are full or empty is sensed. In the stamping station only sections all of whose blisters are full are stamped out of the strip from between the edges thereof while leaving the edges flanking the stamped-out section intact so that sections of the strip having at least one empty blister leave the stamping station attached to the strip edges. The stamped-out sections are transported away from the path at the stamping station. Spaces in the strip between blisters still attached to the strip edges are then detected and the entire strip is transversely cut only between the respective blisters into pieces each including at least one row of intact blisters. | 08-28-2008 |
20080217204 | Child-proof carton package - A childproof package consists of a rectangular folding box of cardboard with at least one strip-like blister pack (B) inside, which can be pulled out from one of the short, narrow sides of the folding box. The folding box is designed to be reclosed in such a way as to be childproof again, and the folding box and the blister pack (B) have cooperating means ( | 09-11-2008 |
20080217205 | Child-proof carton package - A childproof package consists of a rectangular folding box of cardboard with at least one strip-like blister pack (B) inside, which can be pulled out from one of the short, narrow sides of the folding box. The folding box is designed so that it can be reclosed in such a way as to be childproof again, and the folding box and the blister pack (B) have cooperating means ( | 09-11-2008 |
20080217390 | Child-proof carton package - A childproof package consists of a rectangular folding box of cardboard with at least one strip-like blister pack inside, which can be pulled out from one of the short, narrow sides of the folding box. The folding box is designed so that it can be reclosed in such a way as to be childproof again, and the folding box and the blister pack have cooperating means, which are designed so that the blister pack cannot be pulled completely out of the folding box. | 09-11-2008 |
20080282646 | Method and Device For Transferring Products From a Supply Vessel Into the Blisters of a Foil - The invention relates to a method for transferring products from a supply vessel ( | 11-20-2008 |
20100308508 | DEVICE AND METHOD FOR THERMOFORMING A SHEET - The device for thermoforming a sheet has two molds. The first mold includes a movable plug support plate and heated plugs projecting from the plug support plate, which plugs are spaced a predetermined distance apart. A plurality of induction coils is arranged stationary in an area of the device adjacent to the plug support plate, and the plug support plate has an induction element of inductively heatable material. | 12-09-2010 |
20110294087 | HEATING PLATE FOR HEATING A SHEET - The heating plate for heating a sheet in a thermoforming machine prior to forming comprises a highly heat-conductive support plate having a working surface, a heating means connected to the support plate, and a wear layer formed as a replaceable wear plate, which is held magnetically to the working surface of the support plate. | 12-01-2011 |
20120241617 | DEVICE FOR INSPECTING SMALL PHARMACEUTICAL PRODUCTS - The device for inspecting separately conveyed tablets or capsules has a guide device for guiding the separately conveyed tablets or capsules, which defines a predetermined tablet pathway, and a heating element designed as a hotplate, which is arranged in an area of the guide device. The device further has an IR sensor for detecting radiation in an infrared range arranged opposite the heating element such that the tablet pathway passes between the heating element and the IR sensor, and an evaluation unit connected to the IR sensor and adapted to compare actual measurement values of the IR sensor with at least one predetermined nominal measurement value. | 09-27-2012 |
20130061560 | METHOD FOR INSERTING COTTON WADS INTO CONTAINERS - The method for inserting cotton wads into containers uses a wad transport unit, which comprises two star wheels, each having three wad holders. The two star wheels are mounted rotatably on the same rotational axis but with an offset from each other, and each star wheel is driven by its own separate drive means. During rotation of the star wheels, one of the three wad holders of each star wheel is horizontally shifted in such a way that the three wad holders of each star wheel are arranged in a straight line and are thus located above three containers to be filled with the wads. | 03-14-2013 |
20130299092 | DEVICE FOR ROLL-SEALING SHEETS - The device for sealing together a formed bottom sheet and a lidding sheet between a feed roll and a sealing roll has a heating unit for preheating the lidding sheet before the sealing operation. The heating unit is a contactless induction heating device which has coils and magnetic-field influencing elements which are arranged transversely to the travel direction of the lidding sheet and opposite at least one of the coils. The distance between each of the magnetic-field influencing elements and the at least one coil is adjusted by a control unit on the basis of measurement values of temperature sensors arranged downstream of the magnetic-field influencing elements in order to regulate the temperature profile of the lidding sheet. | 11-14-2013 |
20130306193 | DEVICE FOR THE QUANTITATIVELY REGULATED DELIVERY OF BULK PRODUCT - The device for the quantitatively regulated delivery of bulk product includes a supply tank for the bulk product and a slider element, which forms the boundary of an outlet gap on one side. The slider element comprises on its front end an elastic, U-shaped loop, the upper part of which is fixed in position, whereas a rear portion of the lower part of the loop is connected to a linear drive. The linear drive can be used both to adjust the width of the outlet gap by translational movement of the lower section of the loop and to produce a small-amplitude back-and-forth movement of the lower section of the loop. In this way, it is possible to release bulk product of various shapes and sizes reliably and without damage in a quantitatively regulated manner. | 11-21-2013 |
20130306625 | SEALING ROLL - The sealing roll includes a stationary internal shaft and an inductively heatable roll jacket supported with freedom to rotate around the shaft. A plurality of induction coils is wound around the shaft over ferrites, which are open to the outside. Cables for the induction coils are laid through a cable conduit in the shaft for connection to an external induction generator. A water cooling channel for indirectly cooling the induction coils is also arranged in the shaft. A cavity is formed in at least an axial subsection of the sealing roll between the roll jacket and the shaft, and at least part of a temperature detection device is arranged in the cavity or adjacent to the cavity so that an IR temperature sensor receives radiation emitted by the roll jacket and thus detects a temperature of the roll jacket. | 11-21-2013 |
Patent application number | Description | Published |
20090099317 | Novel Rubber and Thermoplastic Multi-Component Systems, Rubber and Thermoplastic Composite Moulded Pieces Made Therefrom, Method for Production and Use Thereof - A multicomponent system is provided, composed of a thermoplastic component and of a rubber component, which comprises at least two different peroxidic crosslinking agents with specific decomposition temperatures, as also is a process for production of rubber-thermoplastic composite mouldings using the multicomponent system, and also the resultant rubber-thermoplastic composite mouldings. | 04-16-2009 |
20090202761 | LIGHTWEIGHT COMPONENT OF HYBRID DESIGN - The present invention relates to lightweight components of hybrid design, also termed hybrid components or hollow-chamber lightweight components, composed of a shell-type parent body which is reinforced by means of thermoplastics and is suitable for the transmission of high mechanical loads, where particular flow aids are added to the thermoplastic in order to improve its physical properties. | 08-13-2009 |
20090209697 | Moulding Compositions Based on a Thermoplastic Polycarbonate - This invention relates to thermoplastic moulding compositions with improved flowability based on a thermoplastic polycarbonate and on a copolymer of at least one olefin with at least one methacrylic ester or acrylic ester of an aliphatic alcohol, where the MFI of the copolymer is no less than 100 g/10 min, to a process for preparation of these moulding compositions, and also to the use of these moulding compositions for production of mouldings for the electrical industry, electronics industry, telecommunications industry, motor vehicle industry, or computer industry, in sports, in medicine, in households, or in the entertainment industry. | 08-20-2009 |
20100219381 | THERMALLY CONDUCTIVE AND ELECTRICALLY INSULATING THERMOPLASTIC COMPOUNDS - The present invention relates to thermoplastic moulding compositions based on thermoplastics with an electrically insulating, thermally conductive filler and with a further thermally and electrically conductive filler, and to production of these and to their uses. | 09-02-2010 |
20120193839 | Use of moulding compositions - The present invention relates to the use of moulding compositions comprising A) at least one polyamide and/or copolyamide, B) at least one copolymer comprising at least one olefin and at least one acrylate of an aliphatic alcohol, C) at least one di- or polyfunctional additive which has branching or chain-extending effect, D) at least one impact modifier differing from components B) and C), and optionally also E) other additives differing from the above mentioned components, to produce products, components, mouldings, moulded parts or semifinished products with increased resistance to crankcase gases and/or constituents of these, and also to a process for improving products, mouldings, components or moulded parts in motor vehicles, preferably in internal combustion engines of these, in respect of their resistance to crankcase gases, by using the said moulding compositions to produce the said products. | 08-02-2012 |
20130165567 | MOULD-RELEASE AGENT COMBINATIONS - The present invention relates to mould-release agent combinations for plastics comprising A. at least one amide wax and B. at least one ester wax and/or C. at least one saponified wax, and also to the use of the mould-release agent combinations for plastics, where the plastic is polyamide, and also to thermoplastic moulding compositions based on polyamide comprising these mould-release agent combinations, and to processes for their production. | 06-27-2013 |
20130190443 | Thermoplastic moulding compositions with increased hydrolysis resistance - This invention relates to thermoplastic moulding compositions comprising A) polyamide and/or copolyamide, B) at least one copolymer of at least one olefin and of at least one acrylate of an aliphatic alcohol, C) at least one filler and/or reinforcing material, D) at least one oligomeric and/or polymeric carbodiimide, and optionally also at least one other additive E) and optionally at least one impact modifier F). The invention further relates to mouldings or semifinished products which are produced from the moulding compositions according to the invention, preferably by means of injection moulding. However, the present invention also relates to the use of a substance combination made of at least one component B) and of at least one component D) for improving the hydrolysis resistance of polyamide-based products. | 07-25-2013 |
20130289147 | THERMOPLASTIC MOULDING COMPOUNDS WITH INCREASED MELT STABILITY - This invention relates to substance mixtures for thermoplastic molding compositions, comprising A) polyamide and/or copolyamide, B) copolymers of at least one olefin and of at least one acrylate of an aliphatic alcohol, C) additives with chain-extending effect and D) impact modifiers and optionally also E) other additives and/or F) fillers and reinforcing materials. The invention further relates to processes for producing molding compositions of the invention and molded products or semifinished products which are produced from the substance mixtures of the invention, preferably by means of extrusion or blow molding of the molding compositions to be produced from the substance mixtures. | 10-31-2013 |
20140044943 | MULTILAYER THERMOPLASTIC SEMI-FINISHED FIBER MATRIX PRODUCT - The invention relates to multilayer thermoplastic plate semi-finished products assembled in sandwich construction mode containing a core (A) of continuous fibre-reinforced thermoplastic composite materials or of long-fibre-reinforced thermoplastic composite materials the whole area whereof on the upper- and/or underside is bonded with at least one layer of a formable thermoplastic forming compound (B) which possesses a comparable or higher melting point than the matrix of the fibre-reinforced thermoplastic composite material in the core and at the forming temperature in the range of shear rates from 1/s-100/s displays an at least 10% higher melt viscosity measured according to ISO 11443 at residual moisture content <0.03% wherein the core (A) contains at least one reinforcing fibre and the use thereof in mechanically stressed structural components, preferably in motor vehicles, aircraft or wind power plants. | 02-13-2014 |
20140100305 | MOULDING COMPOSITIONS - This invention relates to polyamide moulding compositions with high resistance to heat/light ageing. | 04-10-2014 |
20150051368 | NOVEL COMPOSITIONS FOR PRODUCING CAST POLYAMIDES - The present invention relates to novel compositions for production of cast polyamides. | 02-19-2015 |
20150057410 | THERMOPLASTIC MOLDING COMPOUNDS - The present invention relates to thermoplastic moulding compositions comprising iron oxalate as stabilizer system with respect to adverse thermooxidative effects. The invention further relates to the use of iron oxalate to improve the stability of thermoplastic moulding compositions with respect to adverse thermooxidative and/or photooxidative effects, and also to processes for the production of the said moulding compositions. | 02-26-2015 |
20150099839 | THERMOPLASTIC MOLDING COMPOUNDS - The present invention relates to a substance mixture comprising a combination of at least one salt of metal cations and of thermally activatable reducing anions and of at least one polyol, to the use of said substance mixture as stabilizer system for thermoplastic molding compositions or for fibers, foils, or moldings to be produced therefrom with respect to thermooxidative or photooxidative degradation, to a process for the production of said thermoplastic molding compositions, and to the fibers, foils, and moldings to be produced therefrom, and also in turn to uses of these. | 04-09-2015 |
20150105506 | THERMOPLASTIC MOULDING COMPOUNDS - The present invention relates to mixtures for thermoplastic moulding compositions based on polyamides with the mineral filler triclinic pinacoidal aluminium silicate and with at least one heat stabilizer, and also at least one additional substance, to the production of these, and also to electrically insulating, thermally conductive products to be produced therefrom, in particular mouldings and semifinished products. | 04-16-2015 |
20150159015 | POLYAMIDE COMPOSITIONS - The present invention relates to compositions based on at least one polyamide containing at least one polyol and at least one copolymer of at least one olefin with at least one methacrylate or acrylate of an aliphatic alcohol, and to processes for producing moulding compositions from the inventive compositions and products that can be produced therefrom, especially fibres, films and mouldings formed from these moulding compositions, and the use thereof. | 06-11-2015 |
Patent application number | Description | Published |
20110059554 | DETERMINING AN EXPRESSION STATUS OF HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 (HER2) IN A BIOLOGICAL SAMPLE - A method for determining an expression of human epidermal growth factor receptor 2 (HER2) of a subject. The method includes providing a sample from the subject; measuring one of (i) amounts of two or more proteins in the sample, each protein having a molecular weight substantially equal to 4740, 8404, 8419, 8435, 8450, 8455, 8465, 8570, 8607 or 8626 atomic mass units, and (ii) amounts of at least one of human cystein-rich intestinal protein 1 (CRIP1), one or more variants of the human cystein-rich intestinal protein 1 (CRIP1 variants), and proteolytic digestion products thereof in the sample; and comparing the amounts of the proteins to control amounts, which control amounts are determinative of the expression of the human epidermal growth factor receptor 2. | 03-10-2011 |
20120129201 | MASS SPECTROMETRY IMAGING WITH SUBSTANCE IDENTIFICATION - A method for the identification and localization of proteins or other biomolecules of a histologic tissue section comprises enzymatically digesting the biomolecules of two similar tissue sections while substantially preserving the biomolecule positions in the tissue sections. Next, a mass spectrometric image of the digest products in one of the tissue sections is acquired. Then, the digest products of the other tissue section are extracted and separated and the mass spectra and daughter ion spectra of all the digest products are acquired. A list of all identifiable biomolecules of the tissue section is created by comparing the mass spectra and daughter ion spectra with spectra in biomolecule structure databases or spectral libraries. Finally, the biomolecules in the list are assigned to digest products of the same mass in the mass spectra used to create the mass spectrometric image of the thin tissue section. | 05-24-2012 |
20120309027 | QUANTITATIVE PEPTIDE ANALYSIS BY MASS SPECTROMETRY - A method for determining the concentration ratio in a sample of a target peptide to a reference peptide that is chemically identical with the target peptide, but labeled by isotopes, acquires mass spectra of the target and reference peptides. One of a plurality of families of superimposed bell-shaped curves which is a best fit to ion current peak groups of the target and reference peptides in the mass spectra is determined by varying parameters of the families. In each family, each bell-shaped curve has a predetermined height, the curves have fixed distances from each other and the relative curve heights and curve distances in the families are individually calculated from an elemental composition of the peptides and an isotope abundance distribution of elements composing the peptides, taking into account purity of the isotopes. The concentration ratio is then determined from the parameters of the best fit. | 12-06-2012 |
20140306104 | HIGH-THROUGHPUT MASS-SPECTROMETRIC CHARACTERIZATION OF SAMPLES - The invention relates to the characterization of samples which are located in their many hundreds up to tens or hundreds of thousands on a sample support plate in a regular pattern, a so-called array, by ionization with matrix-assisted laser desorption and mass spectrometric measurement, for example. The invention proposes that the position of the sample pattern, and thus the position of each sample in the measuring instrument, for example a mass spectrometer, should be determined by measuring at least two finely structured internal position recognition patterns, such as fine crosses. The position recognition patterns are preferably applied as the samples are generated, with the same apparatus which also generates the sample pattern. A mass spectrometer in which laser spots with diameters of only four to five micrometers can be generated, which can preferably be positioned with an accuracy of one micrometer or better, is particularly suitable for the characterization. | 10-16-2014 |
Patent application number | Description | Published |
20140364435 | AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES - The present invention relates to amino-substituted imidazopyndazine compounds of general formula (I): in which A, R1, R2, R3, R4 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 12-11-2014 |
20150087631 | AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES - The present invention relates to amino-substituted imidazopyridazine compounds of general formula (I), in which A, R1, R2, R3, R4, R5 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 03-26-2015 |
20150094300 | AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES - The present invention relates to amino-substituted imidazopyridazine compounds of general formula (I); in which A, R1, R2, R3, R4, R5 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 04-02-2015 |
20150132229 | BIS AZAINOSITOL HEAVY METAL COMPLEXES FOR X-RAY IMAGING - The present invention describes a new class of trinuclear heavy metal complexes comprising two hexadentate azainositol tricarboxylic acid ligands, a method for their preparation and their use as X-ray contrast agents. | 05-14-2015 |
20150133425 | THIENOPYRIMIDINES - The present invention relates to substituted thienopyrimidine compounds of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 05-14-2015 |
20150133426 | SUBSTITUTED PYRROLOPYRIMIDINES - The present invention relates to substituted pyrrolopyrimidine compounds general formula I: in which A, X, R | 05-14-2015 |
20150152121 | Substituted Benzothienopyrimidines - The present invention relates to substituted benzothienopyrimidine compounds of general formula I: in which R | 06-04-2015 |
20150218173 | SUBSTITUTED INDAZOL-PYRROLOPYRIMIDINES USEFUL IN THE TREATMENT OF HYPERFOLIFERATIVE DISORDERS - The present invention relates to substituted indazol-pyrrolopyrimidine compounds of general formula I: in which R | 08-06-2015 |
20150239891 | SUBSTITUTED PYRROLOPYRIMIDINYLAMINO-BENZOTHIAZOLONES AS MKNK KINASE INHIBITORS - The present invention relates to substituted pyrrolopyrimidinylamino-benzothiazolone compounds of general formula I as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 08-27-2015 |
20150252047 | SUBSTITUTED INDAZOL-PYRROLOPYRIMIDINES USEFUL IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES - The present invention relates to substituted indazol-pyrrolopyrimidine compounds of general formula (I): in which R | 09-10-2015 |
20150291599 | AMINOIMIDAZOPYRIDAZINES - The present invention relates to amino-substituted imidazopyridazine compounds of general formula (I), in which A, R1, R2, R3, R4 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 10-15-2015 |
20150376189 | AMIDOIMIDAZOPYRIDAZINES AS MKNK-1 KINASE INHIBITORS - The present invention relates to amido-substituted imidazopyridazine compounds of general formula (I): in which A, R1, R2, R3, R4 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 12-31-2015 |
20160002245 | SUBSTITUTED PYRAZOLOPYRIMIDINYLAMINO-INDAZOLES - The present invention relates to substituted pyrazolopyrimidinylamino-indazole compounds of general formula I as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 01-07-2016 |
20160060209 | BIS AZAINOSITOL HAFNIUM COMPLEXES FOR X-RAY IMAGING - The present invention describes a new class of trinuclear hafnium complexes comprising two hexadentate azainositol carboxylic acid ligands, methods for their preparation and their use as X-ray contrast agents and X-ray diagnostic agents. The claimed compounds can be described by the following Markush formula describing rinuclear hafnium complexes of general formula (I). The following is a compound according to the above Markush formula (example 8). | 03-03-2016 |