Patent application number | Description | Published |
20080214870 | Method of Preparing Amine Stereoisomers - This invention provides intermediates useful in a method of preparing amine stereoisomers. It also provides a method of preparing sulfoxide and sulfinylamine stereoisomers using certain of the intermediates. | 09-04-2008 |
20080293972 | Process for Preparing Substituted Anisidines - Disclosed is a process for preparing substituted anisidines of formula I starting from substituted cyclic hydroxy-ketones II via aromatization through a substituted oxime intermediate IV in which R is C | 11-27-2008 |
20090088571 | Synthesis of 6,7-Dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides - Disclosed is a multi-step process for preparing a compound of Formula I: | 04-02-2009 |
20090124808 | PROCESS FOR PREPARING ACYCLIC HCV PROTEASE INHIBITORS - Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection: | 05-14-2009 |
20090124809 | PROCESS FOR PREPARING ACYCLIC HCV PROTEASE INHIBITORS - Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection: | 05-14-2009 |
20090137815 | Process for Making Cytokine Inhibiting Compounds Containing 4- and 5-Imidazolyl Rings and the Intermediates Thereof - Disclosed are processes for making compounds containing 4- and 5-imidazolyl rings, also disclosed are the inter-mediates useful in the processes disclosed herein. | 05-28-2009 |
20100222585 | PREPARATION OF DIHYDROTHIENO [3, 2-D] PYRIMIDINES AND INTERMEDIATES USED THEREIN - The invention relates to improved methods of preparing dihydrothienopyrimidines of formula 1, and intermediates thereof, (I) wherein X is SO or SO | 09-02-2010 |
20100240879 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATES AND INTERMEDIATES THEREIN - The present invention relates to processes for preparing the compounds of general formula I, | 09-23-2010 |
20110130563 | SYNTHESIS IF DIHYDROTHIENO[3,2-D]PYRIMIDINE DIOLS - The present invention relates to an improved process for the preparation of dihydrothieno[3,2-d]pyrimidine diols, and similar pyrimidine diols, that is efficient, high-yielding, and does not require expensive and potentially unstable intermediates. The diols are used as intermediates in the synthesis of pyrimidine compounds which inhibit PDE4, and are thus useful in the treatment of respiratory or gastrointestinal diseases and complaints, peripheral or central nervous system diseases and disorders, inflammatory conditions, and cancers. | 06-02-2011 |
20110263844 | METHOD FOR PREPARING MACROCYCLES - The present invention is directed to a method for the preparation of macrocyclic compounds of formula (I), | 10-27-2011 |
20120277455 | NOVEL CHIRAL PHOSPHORUS LIGANDS - The invention relates to a series of novel chiral phosphorus ligands of formulae (Ia) and (Ib): wherein R, 1-rR>4 and X are as defined herein. The invention also relates to chiral metal complexes prepared with these chiral phosphorus ligands. The chiral metal complexes are useful as catalysts for carrying out asymmetric hydro genation. | 11-01-2012 |
20130059866 | NOVEL PIPERIDINO-DIHYDROTHIENOPYRIMIDINE SULFOXIDES AND THEIR USE FOR TREATING COPD AND ASTHMA - The invention relates to novel piperidino-dihydrothienopyrimidine sulfoxides of formula I, | 03-07-2013 |
20130079359 | NOVEL PIPERIDINO-DIHYDROTHIENOPYRIMIDINE SULFOXIDES AND THEIR USE FOR TREATING COPD AND ASTHMA - The invention relates to novel piperidino-dihydrothienopyrimidine sulfoxides of formula I, | 03-28-2013 |
20140135493 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS - Disclosed is a process for making diastereomeric compound of the formula (I): wherein m, n and R | 05-15-2014 |
20140135506 | PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS - Disclosed are methods for making chiral phosphorus ligands including chiral phosphines, chiral phosphine oxides, phosphonamides, and aminophosphines. The chiral phosphorus ligands prepared by the methods of the invention are useful as components of chiral catalysts, e.g., transition metal complexes. | 05-15-2014 |
20140171692 | PROCESS FOR ASYMETRIC METHYLALLYLATION IN THE PRESENCE OF A 2,2'-SUBSTITUTED 1,1'-BI -2-NAPHTHOL CATALYST - Disclosed are a process and catalysts useful for carrying out asymmetric methlyallylations. The catalysts used in the invention have the formula (IV): wherein X | 06-19-2014 |
20150018555 | NOVEL CHIRAL NITROGEN-PHOSPHORUS LIGANDS AND THEIR USE FOR ASYMMETRIC HYDROGENATION OF ALKENES - The invention relates to a series of novel chiral nitrogen-phosphorus ligands of formulae (Ia) and (Ib): | 01-15-2015 |
20150045376 | NOVEL PIPERIDINO-DIHYDROTHIENOPYRIMIDINE SULFOXIDES AND THEIR USE FOR TREATING COPD AND ASTHMA - Piperidino-dihydrothienopyrimidine sulfoxides of formula I | 02-12-2015 |