Saxon, US
Andrew Saxon, Santa Monica, CA US
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20090136493 | MODIFIED FUSION MOLECULES FOR TREATMENT OF ALLERGIC DISEASE - The present invention comprises a fusion molecule comprising a Fcε fragment sequence including functionally active CH2, CH3 and CH4 domains of the constant region of an IgE heavy chain (CHε2-CHε3-CHε4 sequence) linked at its C-terminus to the N-terminus of a second polypeptide including functionally active hinge, CH2 and CH3 domains of the constant region of an IgG | 05-28-2009 |
20090317389 | FUSION MOLECULES AND METHODS FOR TREATMENT OF IMMUNE DISEASES - The invention concerns bifunctional fusion molecules, and novel, safer and more efficacious methods for the treatment of immune disorders resulting from excessive or unwanted immune responses. The invention provides methods for the suppression of type I hypersensitive (i.e., IgE-mediated) allergic conditions, methods for the prevention of anaphylactic responses that occur as a result of traditional peptide immunotherapies for allergic and autoimmune disorders, and provides novel methods for the treatment of autoimmune conditions, where the methods have reduced risk of triggering an anaphylactic response. The invention provides novel therapeutic approaches for the treatment of allergic responses, including the prevention of anaphylactic response that can occur from environmental allergen exposure. The invention also provides methods for the treatment of autoimmune disorders such as multiple sclerosis, autoimmune type I diabetes mellitus, and rheumatoid arthritis. The invention also provides methods for preventing anaphylactic response during traditional antigen therapies. | 12-24-2009 |
20110020373 | IGE DIRECTED DNA VACCINATION - This invention is directed to a novel approach for focusing and expressing DNA vaccinates in Antigen Presenting Cells (APCs) mediated through targeting IgE receptors (FcεRs) on APC and driving DNA expression through provision of an APC specific regulatory element This vaccine can be used in the prevention or treatment of allergic disease. | 01-27-2011 |
20120148585 | FUSION MOLECULES AND METHODS FOR TREATMENT OF IMMUNE DISEASES - The invention concerns bifunctional fusion molecules, and novel, safer and more efficacious methods for the treatment of immune disorders resulting from excessive or unwanted immune responses. The invention provides methods for the suppression of type I hypersensitive (i.e., IgE-mediated) allergic conditions, methods for the prevention of anaphylactic responses that occur as a result of traditional peptide immunotherapies for allergic and autoimmune disorders, and provides novel methods for the treatment of autoimmune conditions, where the methods have reduced risk of triggering an anaphylactic response. The invention provides novel therapeutic approaches for the treatment of allergic responses, including the prevention of anaphylactic response that can occur from environmental allergen exposure. The invention also provides methods for the treatment of autoimmune disorders such as multiple sclerosis, autoimmune type I diabetes mellitus, and rheumatoid arthritis. The invention also provides methods for preventing anaphylactic response during traditional antigen therapies. | 06-14-2012 |
Donald Conrad Saxon, Bay Springs, MS US
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20090237509 | MOTION ACTIVATED CAMERA SYSTEM - The present invention provides a motion activated camera system having first and second housings. The first housing includes a motion detector, an illuminator, a transmitter, and a first power supply. The first power supply supplies power to the motion detector, the illuminator, and the transmitter. The motion detector provides a field of coverage for detecting motion. The second housing comprising a camera, a receiver, and a second power supply supplying power to the camera and the receiver. The transmitter transmits a signal to the receiver to instruct the camera to record an image when the motion detector detects apparent motion within the field of coverage. The present invention also includes a method of using a motion activated camera. | 09-24-2009 |
Douglas J. Saxon, Colorado Springs, CO US
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20130086540 | SYSTEM AND METHOD OF AUTOMATED DESIGN AUGMENTATION FOR EFFICIENT HIERARCHICAL IMPLEMENTATION - A hierarchical interface module includes an assessment unit configured to identify a hierarchical implementation incompatibility of an integrated circuit (IC) partitioned block. Additionally, the hierarchical interface module includes an interface unit configured to substitute a directly registered hierarchical interface structure for the hierarchical implementation incompatibility of the IC partitioned block. A method of interfacing hierarchically and a hierarchical implementation system are also included. | 04-04-2013 |
20130262946 | METHODS AND STRUCTURE FOR CORRELATION OF TEST SIGNALS ROUTED USING DIFFERENT SIGNALING PATHWAYS - Methods and structure for correlating internal operational signals routed via different paths of a test signal selection hierarchy. The structure includes a functional block of circuitry operable to generate internal operational signals and clock signals. The integrated circuit also comprises a test signal selection hierarchy operable to receive the internal operational signals and the clock signals and to selectively route the internal operational signals and the clock signals. Further, structure includes a control unit operable to receive the clock signals from the test signal selection hierarchy, to determine a delay between received clock signals routed via different signaling pathways of the test signal selection hierarchy. The control unit is further operable to program a delay line based upon the delay between the clock signals and based upon internal operational signals correlated with the clock signals. | 10-03-2013 |
20140130000 | STRUCTURAL RULE ANALYSIS WITH TCL SCRIPTS IN SYNTHESIS OR STA TOOLS AND INTEGRATED CIRCUIT DESIGN TOOLS - A method of designing a circuit, an apparatus and a structural analysis tool are disclosed. In one embodiment, the structural analysis tool includes: (1) a structural analyzer configured to apply a structural rule to the circuit design in a design environment of said design process having valid timing data and (2) a structural assessor configured to generate structural data of the circuit design based on application of the structural rule by the structural analyzer. | 05-08-2014 |
Earl Thomas Saxon, North Augusta, SC US
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20090140539 | Rear Bag Cover and Method of Attachment By Brackets - The invention is an apparatus and method for attaching a cover to a golf cart by brackets and the brackets themselves. The tension supplied by the brackets may be the only mechanism by which the cover mounts to the golf cart. Brackets are preferably configured for attachment to the roof of the golf cart. The apparatus may include brackets for mounting the cover to the roof, a stationary main frame member, a movable frame member, and a cover. Brackets receive the stationary frame member. The movable frame member is operatively secured to the stationary main frame member, and configured to pivotably rotate over a portion of the rear compartment of the golf cart. The cover is configured for attachment to the movable frame member so that when the movable frame member rotates over a portion of the rear compartment of the golf cart, the cover covers a portion of the rear compartment of the golf cart. | 06-04-2009 |
Eliana Saxon, Albany, CA US
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20080214801 | CHEMOSELECTIVE LIGATION - The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids). | 09-04-2008 |
20110236930 | CHEMOSELECTIVE LIGATION - The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids). | 09-29-2011 |
Eugene A. Saxon, Seattle, WA US
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20110045451 | Apparatus and Method for Simulating Arterial Blood Flow Under Various Pressure Conditions - An apparatus and method for simulating human ophthalmic artery for testing of ultrasound devices is disclosed, whereby two chambers are provided and are capable of being independently pressurized, one representing the intra-cranial space and the other representing extra-cranial space, and whereby a tube running through both chambers is provided, simulating the course of the ophthalmic artery and capable of being pressurized to stimulate arterial pressure. The apparatus is operated by pressuring both chambers, and pumping a blood-imitating fluid through the vessel in a pulsatile manner. | 02-24-2011 |
Gene Saxon, Seattle, WA US
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20100331684 | Method and Apparatus For Determining The Absolute Value Of Intracranial Pressure - A method and apparatus for obtaining the absolute value of intracranial pressure in a non-invasive manner is described by using an ultrasonic Doppler measuring device which detects the intracranial and extracranial blood flow velocities of the intracranial and extracranial segments of the ophthalmic artery. The eye in which the blood flow is monitored is subjected to an external pressure, sufficient to equalize the intracranial and extracranial angle-independent blood flow factors calculated from the intracranial velocity signal and extracranial velocity signal. The absolute value of the intracranial pressure is identified as that external pressure at which such equalization occurs. | 12-30-2010 |
Gregory J. Saxon US
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20130192049 | SYSTEM FOR PLUGGING HEAT EXCHANGING TUBES - A system and a method for plugging a heat exchanger tube or the like. The system includes a plug member having a central shaft having a compressible member mounted on the central shaft such that axial compression of the compressible member radially expands the compressible member into sealing engagement with an inner wall of a tube in which the plug member is inserted. The system further includes a drive means removably engaged with the plug member for inserting the plug member into the tube and for providing axial force on the compressible member to cause radial expansion of the compressible member into sealing engagement with the inner wall of the tube. | 08-01-2013 |
Gregory J. Saxon, Oakmont, PA US
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20120175078 | HEAT EXCHANGER TUBE CLEANING APPARATUS AND METHOD OF REMOVING A BLOCKAGE FROM A TUBE - A cleaning apparatus for removing a blockage from a heat exchanger tube of a steam generator, or the like, having a plurality of tubes extending between a pair of tube sheets. Anchor plate fasteners, which are expandable inside tubes adjacent to the blocked tube, are used to mount an anchor plate to one of the tube sheets. The anchor plate has an opening for aligning in registry with the condenser tube having the blockage and provides a solid platform for mounting either a mechanical device or a fluid pressure device for providing a force against the blockage for removal of the blockage. The cleaning apparatus enables a force to be applied which is significantly greater than that which can be applied with known hand-held devices for removing blockages. | 07-12-2012 |
Hayes I. Saxon, Cedar Park, TX US
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20090126002 | SYSTEM AND METHOD FOR SAFEGUARDING AND PROCESSING CONFIDENTIAL INFORMATION - One aspect of the invention is a method for providing restricted access to confidential services without impacting the security of a network. The method includes using a gateway to isolate one or more components providing confidential services from one or more other portions of an enterprise network. A first communication directed to a selected one of the one or more components may be received at the gateway. A determination may be made as to whether the first communication is user traffic or management traffic. The first communication may then be authenticated. If the first communication is user traffic, the first communication is forwarded to a component providing the confidential services. If the first communication is management traffic, the first communication is encrypted and forwarded to a component providing the confidential services. Additionally, components of the sub-network may be monitored to identify malicious changes. | 05-14-2009 |
Jack Saxon, Eagan, MN US
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20140304009 | SYSTEM AND METHOD FOR MANAGEMENT OF INSURABLE ASSETS - Systems and methods for managing insurable assets in a multi-party process. An insurable asset management system includes a data store, in which one or more data structures are stored. Each data structure represents assets for a corresponding location and a corresponding client account. The system further includes hardware comprising a processor-based computing system and a set of instructions executable by the system hardware and stored in a non-transitory storage medium that facilitates access to the data structure for clients, delegatees, and insurers. | 10-09-2014 |
Joe Saxon, Cookeville, TN US
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20090065447 | FILTRATION SYSTEM WITH A VARIABLE RESTRICTION ORIFICE - Various “no filter, no run” fuel filtration designs are described that include a variable restriction orifice (VRO) designed to vary the amount of fluid, for example fuel, that reaches a fluid outlet. The VRO has a fully open position at which a maximum non-zero fluid flow is permitted, and a fully closed position at which a limited amount of fluid can flow to the outlet. In the case of diesel fuel, the amount of fuel flow permitted at the fully closed position provides lubrication of downstream fuel system components, for example the fuel pump, but is insufficient to permit engine operation. | 03-12-2009 |
Jonathan Aaron Saxon, New York, NY US
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20150111418 | APPARATUSES AND METHODS RELATING TO EXTENSION CORD WITH INTEGRATED CORD MANAGEMENT - One exemplary aspect comprises an apparatus comprising: (a) a first housing comprising an electrical plug; (b) a second housing comprising an electrical receptacle; and (c) a first electrical cord connecting the first housing to the second housing; wherein the second housing is configured to accept the electrical cord being wound around the second housing. In an exemplary embodiment, the apparatus further comprises a third housing comprising an electrical receptacle; and a second electrical cord connecting the second housing to the third housing; wherein the third housing is configured to accept the second electrical cord being wound around the second housing. | 04-23-2015 |
Michael Scott Saxon, Westfield, NJ US
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20130014138 | Mobile Remote Media Control Platform Methods - The MOBILE REMOTE MEDIA CONTROL PLATFORM METHODS (“MR-Control”) transforms TV program schedule listing information and user channel selection via MR-Control components, into TV audience viewing data and ad effects data. A method is disclosed, comprising: obtaining TV program schedule listing data; providing the obtained TV program schedule listing data to a user mobile device; receiving an indication of user channel selection; determining a media program associated with the received indication of user channel selection; determining an ad associated with the determined media program; providing a survey question related to the determined ad to the user mobile device; and receiving a user response to the survey question. | 01-10-2013 |
20130019258 | MEDIA CONTENT BASED ADVERTISING SURVEY PLATFORM METHODS - The MEDIA CONTENT BASED ADVERTISING SURVEY PLATFORM METHODS (“AD-SURVEY”) transforms user advertisement exposure data via AD-SURVEY components, into ad effects data including user responses to survey questions. A method is disclosed, comprising: obtaining TV program schedule listing data including a plurality of ad tags at a server; providing the obtained TV program schedule listing data to a user mobile device, receiving a user media program selection message from the user mobile device; retrieving an ad tag associated with the user selected media program from the TV program schedule listing data; extracting key terms from the ad tags based by parsing ad contents; querying a survey question list based on the extracted key terms; generating and sending a survey question from the query to the user mobile device; and obtaining a user reaction to the survey question. | 01-17-2013 |
20140173641 | Social Content Monitoring Platform Apparatuses, Methods and Systems - The SOCIAL CONTENT MONITORING PLATFORM METHODS (“Social-Watch”) transforms social media contents via Social-Watch components, into ad effects data. A method is disclosed, comprising: identifying a request to access user social media content; obtaining user authorization credentials to access user social media content; sending an access request with the obtained user authorization credentials to a social media platform; receiving social media content data from the social media platform; determining a type of the received media content data; tagging the received media content data based on the type according to a progressive taxonomy mechanism; receive a social media analytics request for an item; querying the tagged media content data based on key terms related to the item; and determining impression heuristics for the item based on query results. | 06-19-2014 |
20140173643 | Mobile Content Tracking Platform Apparatuses, Methods and Systems - The MOBILE CONTENT TRACKING PLATFORM METHODS (“Mobile-Track”) transforms TV program schedule listing information and user channel selection via Mobile-Track components, into TV audience viewing data and ad effects data. A method is disclosed, comprising: obtaining TV program schedule listing data; providing the obtained TV program schedule listing data to a user mobile device; receiving an indication of user channel selection; determining a media program associated with the received indication of user channel selection; determining an ad associated with the determined media program; providing a survey question related to the determined ad to the user mobile device; and receiving a user response to the survey question. | 06-19-2014 |
20150334469 | Media Content Synchronized Advertising Platform Apparatuses and Systems - The MEDIA CONTENT SYNCHRONIZED ADVERTISING PLATFORM APPARATUSES AND SYSTEMS (“AD-SURVEY”) transforms user advertisement exposure data via AD-SURVEY components, into ad effects data including user responses to survey questions. A system is disclosed, comprising: a memory; a processor disposed in communication with said memory, and configured to issue a plurality of processing instructions stored in the memory, wherein the processor issues instructions for obtaining TV program schedule listing data including a plurality of ad tags at a server: providing the obtained TV program schedule listing data to a user mobile device, receiving a user media program selection message from the user mobile device; retrieving an ad tag associated with the user selected media program from the TV program schedule listing data; extracting key terms from the ad tags based by parsing ad contents; querying a survey question list based on the extracted key terms; generating and sending a survey question from the query to the user mobile device; and obtaining a user reaction to the survey question. | 11-19-2015 |
20150358667 | Mobile Remote Media Control Platform Apparatuses and Systems - The MOBILE REMOTE MEDIA CONTROL PLATFORM APPARATUSES AND SYSTEMS (“MR-Control”) transforms TV program schedule listing information and user channel selection via MR-Control components, into TV audience viewing data and ad effects data. A system is disclosed, comprising: a memory; a processor disposed in communication with said memory, and configured to issue a plurality of processing instructions stored in the memory, wherein the processor issues instructions for: obtaining TV program schedule listing data; providing the obtained TV program schedule listing data to a user mobile device; receiving an indication of user channel selection; determining an ad associated with the determined media program; providing a survey question related to the determined ad to the user mobile device; and receiving a user response to the survey question. | 12-10-2015 |
20160088333 | Media Content Synchronized Advertising Platform Apparatuses and Systems - The MEDIA CONTENT SYNCHRONIZED ADVERTISING PLATFORM APPARATUSES AND SYSTEMS (“AD-SYNCH”) transforms TV program schedule listing information and user channel selection via AD-SYNCH components, into channel-synchronized product placement advertisement. A system is disclosed, comprising: a memory; a processor disposed in communication with said memory, and configured to issue a plurality of processing instructions stored in the memory, wherein the processor issues instructions for: providing TV program schedule listing data including a plurality of ad tags to a user mobile device, receiving a user media program selection message from the user mobile device; retrieving an ad tag associated with the user selected media program from the TV program schedule listing data; identifying an advertised item embedded in the media program based on the retrieved ad tag; determining an available ad template associated with the retrieved ad tag; generating an ad for the embedded advertised item based on the available ad template; and providing the generated ad to the user mobile device based on a timestamp of the ad tag. | 03-24-2016 |
Reggy Saxon, Lake Charles, LA US
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20110206489 | Load transport system and method - A motorized means of transporting loads includes a fork lift mechanism that features a set of anchored chains fitted to a set of lifting forks for lifting and lowering a load. With a combination electrical/hydraulic system, the lifting and lowering functions can be efficiently obtained. Two load supporting outriggers are provided which can be extended or retracted while transporting a load to aid in navigating constricted spaces. A tilting mast and fork assembly allows for a manipulation of the center of gravity while transporting loads. A joystick function controls the forward, turning, reverse, lifting, and extending and retracting the outriggers. A battery enabled transport provides for flash charging of the onboard batteries to extend useful life. | 08-25-2011 |
Steve Saxon US
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20110244440 | Cloud Based Test Environment - Systems and methods described herein provide for administering and proctoring of a secure online examination utilizing a ‘cloud’ computing environment. The cloud computing environment provides scalable, shared computing resources such as processing, memory, communications, storage and other hardware and software resources associated with the online examination. The computing resources provided by the cloud computing environment can be provisioned dynamically to match the requirements of the particular computing tasks carried out at the client and/or server level during the administration of the examination. | 10-06-2011 |
Thomas Jason Saxon, Madeira Beach, FL US
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20080313801 | TELESCOPING SHOWER FOR A BOAT - An application for a telescoping boat shower includes telescoping extensions of decreasing diameter that collapse inside of a fishing pole holder of a boat when in storage and extend upwardly from the fishing pole holder when in use. The telescoping extensions conduct water from a larger, lower telescoping extension to a smaller, upper telescoping extension where a nozzle is attached. The nozzle sprays water on a user of the telescoping shower. An adaptable fitting attaches to a bottom of the fishing pole holder, providing a water-tight seal. The adaptable fitting has a water supply fitting for attaching to a supply of water and the adaptable fitting conducts water from the water supply to the telescoping extensions. | 12-25-2008 |
William Ward Saxon, Gainesville, FL US
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20160065438 | METRIC DRIVEN HOLISTIC NETWORK MANAGEMENT SYSTEM - A metric driven method for managing a network can include the step of specifying a profile for a network event. The profile can include multiple discrete factors and can be associated with at least one event operation. Metrics can be received from multiple remotely located components residing within a network space. The metrics can be compared to the discrete factors, where each compared metric can correspond to one of the factors. A determination based on this comparison can indicate whether the network event has occurred. When the network event has occurred, the previously specified event operation associated with the network event can be automatically executed. | 03-03-2016 |