Patent application number | Description | Published |
20080286210 | NOVEL ANTIMICROBIAL PEPTIDES - This invention provides novel antimicrobial peptides that are effective to inhibit growth and/or proliferation of various gram positive bacteria. In particular, the peptides are effective against | 11-20-2008 |
20090098050 | CALCIUM BINDING PEPTIDES - Disclosed herein are a class of compounds comprising peptides of the sequence (X-Y-Z) | 04-16-2009 |
20090298707 | SPARSE MATRIX SYSTEM AND METHOD FOR IDENTIFICATION OF SPECIFIC LIGANDS OR TARGETS - In certain embodiments, this invention pertains to the creation of “Sparse Matrix” libraries of compounds. The sparse matrix libraries of this invention typically span an n-dimensional parameter (property) space at extremely sparse intervals and thereby provide a relatively small library of compounds (e.g., a library of about 200 or fewer compounds) that can be used to quickly and efficiently screen the compound parameter space for one or more desired physical, chemical, or biological properties (e.g., binding specificity, binding avidity, γtoxicity, solubility, mobility, cell permeability, serum half-life, biocompatibility, etc.). | 12-03-2009 |
20100184654 | ANTI-MICROBIAL TARGETING CHIMERIC PHARMACEUTICAL - The present invention is based on the discovery of a composition that provides targeted anti-microbial effect. Specifically the composition contains a targeting moiety which recognizes a target microbial organism and an anti-microbial peptide moiety which has anti-microbial activity. In addition, the present invention provides methods of treating a microbial infection, e.g., on mucosal surfaces by using the compositions provided by the present invention. | 07-22-2010 |
20100239503 | CALCIUM-BINDING AGENTS INDUCE HAIR GROWTH AND/OR NAIL GROWTH - This invention provides novel methods for inducing hair growth and/or inhibiting hair loss and/or inducing nail growth in a mammal. In various embodiments the methods involve administering, e.g., to a mammal in need thereof, a calcium-binding peptide and/or peptide-like moiety in an amount sufficient to induce hair growth and/or to inhibit hair loss. In certain embodiments the agent is topically and/or transdermally administered. | 09-23-2010 |
20100316643 | TARGETED ANTIMICROBIAL MOIETIES - This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species. | 12-16-2010 |
20110085989 | NOVEL ANTIMICROBIAL PEPTIDES - This invention provides novel antimicrobial peptides that are effective to inhibit growth and/or proliferation of various gram positive bacteria. In particular, the peptides are effective against | 04-14-2011 |
20110207657 | Selectively Targeted Antimicrobial Peptides and the Use Thereof - The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., | 08-25-2011 |
20140142028 | TARGETED ANTIMICROBIAL MOIETIES - This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species. | 05-22-2014 |
20140155317 | SELECTIVELY TARGETED ANTIMICROBIAL PEPTIDES AND THE USE THEREOF - The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., | 06-05-2014 |