Loebel, WA
Nicholas Loebel, Woodinville, WA US
Patent application number | Description | Published |
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20090093470 | PHOTODYNAMIC THERAPY PROCESS AND PHOTOSENSITIZER COMPOSITIONS THEREFOR - A process of performing photodynamic therapy is provided along with a photosensitizer composition suitable for the process. The photosensitizer composition comprises at least one photoactive ingredient in a chemically reduced state. According to the process, the photosensitizer composition having at least one photoactive ingredient in a chemically reduced state is provided. The photosensitizer composition is applied to tissue or other substrate such that the at least one photoactive ingredient is at or travels to a location adjacent a target medium and the at least one photoactive ingredient is then altered to a photoactive state. The at least one photoactive ingredient is then exposed to light energy for assisting in inhibiting at least one pathogen at the target medium. | 04-09-2009 |
20100233022 | COMPOSITION FOR PHOTODYNAMIC DISINFECTION - The present invention includes a composition for enhancing the antimicrobial efficacy of photodynamic disinfection against Gram-negative organism that is receptive to paraben potentiation using a composition comprising a photosensitizer and at least one paraben. The present invention also includes a method for photodynamic disinfection comprising applying the composition to a desired treatment area and applying light to the desired treatment area at a wavelength absorbed by the photosensitizer so as to inhibit Gram-negative organism located within the treatment area wherein the Gram-negative organism is receptive to paraben potentiation. | 09-16-2010 |
Nicholas G. Loebel, Redmond, WA US
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20090035725 | PHOTODISINFECTION OF ORAL CAVITY - A composition for photodisinfection of the oral cavity comprising toothpaste and a photosensitizing composition encapsulated within microspheres, wherein the microspheres release the photosensitizing composition into the oral cavity upon contact with liquid and/or force and the photosensitizing composition includes a photosensitizer that upon irradiation of at least one predetermined wavelength will reduce and/or eliminate microbes in the oral cavity. The present invention also includes a method of applying the composition into the oral cavity and applying irradiation to the oral cavity at a wavelength or wavelengths absorbed by the photosensitizing composition so as to reduce or eliminate microbes in the oral cavity. | 02-05-2009 |
Nicholas G. Loebel, Woodinville, WA US
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20090234270 | Therapy and device for treatment of nail infections - The present invention includes a method for treating fungal infections, particularly onychomycosis. The method includes: applying a composition includes a photosensitizer, an effective amount of antifungal agent, and a pharmaceutically acceptable delivery system to a locus and irradiating the locus with a light source at a wavelength absorbed by the photosensitizer so as to destroy microbes at the locus. The present invention also includes a light delivery device for use in photodynamic treatment of onychomycosis comprising (i) a housing adapted to cover a nail beneath which a locus is situated; (ii) a light source; (iii) an energy source in power communication to the light source; and a controller that controls amount of light to be applied to the locus by the light source. | 09-17-2009 |
Nicolas Loebel, Redmond, WA US
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20090317293 | METHOD AND DEVICE FOR ELIMINATING MICROBES WITHIN INDUSTRIAL PIPELINES - The present invention provides a method to inhibit microbes located within a pipeline comprising: applying a photosensitizer composition to a predetermined interior surface area of the pipeline where microbes are located; and applying light to the area at a wavelength that is absorbed by the photosensitizer composition so as to inhibit or eliminate the microbes; wherein the light is applied by a photodynamic disinfection device adapted to provide light to the area. The present invention also provided a photodynamic disinfection device comprising a pipeline inspection gauge (pig) adapted to include a circumferential high energy light source and an energy source wherein the light source is in communication with and powered by the energy source via communication means. | 12-24-2009 |
20100029779 | COMPOSITION AND METHOD FOR TREATMENT OF MRSA - The present invention provides a photosensitizing composition for treatment of MRSA comprising a photosensitizer and chlorhexidine and a pharmaceutically acceptable carrier. The present invention also provides a method for reducing disease causing microbes comprising: applying the composition comprising a photosensitizer, chlorhexidine at a concentration of more than about 0.01% and less than about 2% v/v, and a pharmaceutically acceptable carrier to a treatment site; and applying light to the treatment site at a wavelength absorbed by the photosensitizer so as to reduce the microbes at the treatment site. | 02-04-2010 |
Nicolas Loebel, Woodinville, WA US
Patent application number | Description | Published |
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20120277660 | COMPOSITION AND METHOD FOR TREATMENT OF MRSA - The present invention provides a photosensitizing composition for treatment of MRSA comprising a photosensitizer and chlorhexidine and a pharmaceutically acceptable carrier. The present invention also provides a method for reducing disease causing microbes comprising: applying the composition comprising a photosensitizer, chlorhexidine at a concentration of more than about 0.01% and less than about 2% v/v, and a pharmaceutically acceptable carrier to a treatment site; and applying light to the treatment site at a wavelength absorbed by the photosensitizer so as to reduce the microbes at the treatment site. | 11-01-2012 |
20130310734 | CATHETER FOR PHOTODYNAMIC THERAPY - The present invention provides a multi-functional catheter that can be used to irrigate a treatment site located within a body cavity, to suction waste materials from the treatment site, and to deliver a treatment composition in a generally uniform distribution pattern onto the treatment site. The present invention also provides a method to use this multi-functional catheter for various applications including medical applications (e.g., photodynamic therapy treatment of chronic recurrent sinusitis). | 11-21-2013 |
Nicolas G. Loebel, Redmond, WA US
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20080269205 | METHODS TO PREVENT VERTICAL TRANSMISSION OF INFECTIOUS DISEASES - The present invention presents a method of preventing vertical transmission of an infectious disease comprising: (a) applying a photosensitizing composition to host tissues of birth canal of a mother during the intrapartum period; and (b) applying light to the host tissues after the step (a) at a wavelength absorbed by the photosensitizing composition so as to inhibit or eliminate infectious disease microorganisms that come into contact with the host tissues. The infectious disease may be caused by human immunodeficiency virus type 1, hepatitis B virus, hepatitis C virus, Group B | 10-30-2008 |