Patent application number | Description | Published |
20110100028 | APPARATUS AND METHOD FOR CRYOGRANULATING A PHARMACEUTICAL COMPOSITION - Cryogranulation systems with improved dispenser assemblies are provided for use in manufacturing frozen pellets of pharmaceutical substances in a fluid medium. Methods of cryogranulating the pharmaceutical substance in the fluid medium are also provided. In particular embodiments, the dispenser assembly is used with suspensions or slurries of pharmaceutical compositions including biodegradable substances, such as proteins, peptides, and nucleic acids. In certain embodiments, the pharmaceutical substance can be adsorbed to any pharmaceutically acceptable carrier particles suitable for making pharmaceutical powders. In one embodiment, the pharmaceutical carrier can be, for example, diketopiperazine-based microparticles. The dispenser assembly improves the physical characteristics of the cryopellets formed and minimizes product loss during processing. | 05-05-2011 |
20140044790 | APPARATUS AND METHOD FOR CRYOGRANULATING A PHARMACEUTICAL COMPOSITION - Cryogranulation systems with improved dispenser assemblies are provided for use in manufacturing frozen pellets of pharmaceutical substances in a fluid medium. Methods of cryogranulating the pharmaceutical substance in the fluid medium are also provided. In particular embodiments, the dispenser assembly is used with suspensions or slurries of pharmaceutical compositions including biodegradable substances, such as proteins, peptides, and nucleic acids. In certain embodiments, the pharmaceutical substance can be adsorbed to any pharmaceutically acceptable carrier particles suitable for making pharmaceutical powders. In one embodiment, the pharmaceutical carrier can be, for example, diketopiperazine-based microparticles. The dispenser assembly improves the physical characteristics of the cryopellets formed and minimizes product loss during processing. | 02-13-2014 |
Patent application number | Description | Published |
20090051350 | DEVICE AND PROCESS FOR DETECTING PARTICLES IN A FLOWING LIQUID - A process and device for detecting electrically conductive particles in a liquid flowing in a pipe section, the liquid being exposed to periodic alternating electromagnetic fields by a transmitter coil which induces eddy currents in the particles, a probe made as a coil arrangement and which has an effective width producing a periodic electrical signal based on the eddy currents. The signal ha a carrier oscillation with an amplitude and/or phase which is modulated by particles passing across the effective width of the coil arrangement, the probe signal being filtered by a frequency-selective first filter unit, the filtered signal being sampled by a triggerable A/D converter stage to obtain a demodulated digital measurement signal, the digital measurement signal being filtered by a digital, frequency-selective adjustable second filter unit to obtain a useful signal, and the useful signal being evaluated to detect passage of electrically conductive particles in the pipe section. | 02-26-2009 |
20090217101 | PROCESS AND DEVICE FOR MONITORING A MACHINE - A process for monitoring a machine, within the framework of a FMEA process for at least one component of the machine for at least one predetermined fault which can be diagnosed by means of a diagnosis diagram and a diagnosis system with sensors for detecting physical parameters of the machine, a diagnosis priority number being determined which is the product of the following index quantities: severity of the effect of occurrence of the fault with respect to the serviceability of the machine; expected machine-specific consequential costs when a fault occurs, and the possibility of correction of the fault. The diagnosis priority number is used in the evaluation of the diagnosis diagram, the diagnosis system, the current machine state, the necessary maintenance measures and/or the failure risk of the machine. | 08-27-2009 |
20100082276 | PROCESS FOR MONITORING A DRIVE TRAIN COMPONENT OF A WIND POWER PLANT - A process for monitoring a drive train component ( | 04-01-2010 |
20100158434 | METHOD AND DEVICE FOR DYNAMIC MEASUREMENT OF THE RADIAL DEFORMATION OF A ROLLING BEARING RING - A method and a device for dynamic measurement of the radial deformation of a bearing ring ( | 06-24-2010 |
20110049886 | DEVICE AND METHOD FOR DETECTING THE LOADING OF PIVOTED ROTOR BLADES - A method and a device for measuring the loading on rotor blades, especially of wind power plants with swiveling rotor blades, the loading of the rotor blades being determined by way of deformation of a bearing ring of the swiveling rotor blade takes place economically with proximity sensors, but can also take place advantageously with fiber optic sensors. With an electronic evaluation device, the deformation of the bearing ring is referenced to the loading of the rotor blade. In one advantageous embodiment, an inclinometer is also provided. | 03-03-2011 |
20110179863 | DEVICE AND METHOD FOR MONITORING OF ROTATING MACHINE ELEMENTS - A rotating machine element is monitored for displacements using co-rotating sensors for acceleration, rotation or the direction of gravitation. In doing so, the sensor data are received by a, likewise, co-rotating electronic unit. The data can also be stored and further processed in this electronic unit. | 07-28-2011 |
Patent application number | Description | Published |
20110025458 | METHOD AND APPARATUS FOR AUTHENTICATING RFID TAGS - In an RFID system, a method and apparatus for linking an RFID tag to an associated object. The system includes a relatively simple tag, a reader, a linker, and a store. The reader interrogates the tag for an ID and selectively provides the ID to the linker. The linker, in turn, uses the ID to provide back to the reader an associated Uniform Resource Identifier (“URI”). The reader then forwards the URI to the store. In response, the store returns to the reader the object associated with the ID via the URI. The disclosed method and apparatus provide more efficient and secure tag authentication. | 02-03-2011 |
20110291810 | Method and Apparatus for Detecting RF Field Strength - A method and apparatus for detecting RF field strength. A field strength reference generator develops a field strength reference current as a function of a field strength of a received RF signal; and a field strength quantizer develops a digital field-strength value indicative of the field strength reference current. In one embodiment, detected field strength is used to dynamically vary the impedance of a tank circuit whereby, over time, induced current is maximized. In another embodiment, using the quantized field strength to sense changes to the environment to which the RFID tag is exposed. | 12-01-2011 |
20110300808 | Method and Apparatus for Detecting RF Field Strength - A method and apparatus for detecting RF field strength. A field strength reference generator develops a field strength reference current as a function of a field strength of a received RF signal; and a field strength quantizer develops a digital field-strength value indicative of the field strength reference current. In one embodiment, detected field strength is used to dynamically vary the impedance of a tank circuit whereby, over time, induced current is maximized. | 12-08-2011 |
20140120836 | Method and Apparatus for Detecting RF Field Strength - A method and apparatus for detecting RF field strength. A field strength reference generator develops a field strength reference current as a function of a field strength of a received RF signal; and a field strength quantizer develops a digital field-strength value indicative of the field strength reference current. In one embodiment, detected field strength is used to dynamically vary the impedance of a tank circuit whereby, over time, induced current is maximized. | 05-01-2014 |
Patent application number | Description | Published |
20080197959 | CONNECTOR INCLUDING ISOLATION MAGNETIC DEVICES CAPABLE OF HANDLING HIGH SPEED COMMUNICATIONS - An electric device capable of handling high speed data communication and which could be used with, for example, a connector application such as an RJ45 type connector. The electric device is formed by inserting at least one wire through a first hole in a core, wrapping the wire around a side of the core, and inserting the wire through a second hole in the core a desired number of times. A common mode choke may be combined with the electric device. To form such a choke, two of the wires from the electric device may be wrapped around a second core in the same fashion a desired number of times. | 08-21-2008 |
20080200060 | Electrical Isolation Device Capable Of Limiting Magnetic Saturation Even Upon Receipt Of High Power DC Bias And Method For Making The Same - An electrical device is produced by winding wires around a core. The device may be used as a transformer. Wires are inserted into, through and around a first hole and a first side of a core a desired number of times. Thereafter, the wires are extended along either a top or a bottom of the core and then passed through and around a second hole of the core. After the wires are wound around the second hole of the core and a second side of the core, the production of the device is complete. | 08-21-2008 |
20100045420 | Isolation Magnetic Devices Capable Of Handling High Speed Communications - An isolation magnetic device produced by inserting a first end of a wire through a first hole of a core, wrapping the first end of the wire around a first side of the core and inserting the first end of the wire through a second hole of the core. The second hole of the core is spaced from the first hole and has a longitudinal axis extending parallel to a longitudinal axis of the first hole. The device is further produced by inserting a second end of the wire through the second hole of the core, wrapping the second end of the wire around the first side of the core and inserting the second end of the wire through the first hole of the core. | 02-25-2010 |
20110001596 | Electrical Device Including A Transformer With A Core Having Two Holes And Connector Incorporating The Same - An electrical device is produced by winding wires around a core. The device may be used as a transformer. Wires are inserted into, through and around a first hole and a first side of a core a desired number of times. Thereafter, the wires are extended along either a top or a bottom of the core and then passed through and around a second hole of the core. After the wires are wound around the second hole of the core and a second side of the core, the production of the device is complete. | 01-06-2011 |
Patent application number | Description | Published |
20100073453 | METHODS AND SYSTEMS FOR VISUAL VOICE CALLS - In an exemplary method, at least one telephony attribute associated with a voice call directed from a client communication subsystem to a voice network identifier is detected. Visual content that has been predefined as being associated with the at least one telephony attribute is identified. A request for the visual content is initiated in response to the detecting step. The visual content is received, in response to the initiating step, for display at the client communication subsystem. | 03-25-2010 |
20100121934 | MANAGED PEER-TO-PEER FILE SHARING - A system and method for managed peer-to-peer (p2p) file sharing. The peer nodes can include a web browser and a p2p agent. The web browser can connect to the Internet and can interface with the p2p agent. The p2p agent provides the file sharing utilities for implementing the p2p network. A web server connected to the Internet can monitor and manage p2p activity, including providing persistent storage for the p2p networks. The web server can interface with a Public Switched Telephone Network (PSTN) to provide access to the p2p network for PSTN peer nodes that do not have web browsing capabilities. A method of implementing managed p2p file sharing includes registering users; providing login and logout functions; creating p2p sessions; preparing, forwarding, receiving, accepting and/or rejecting invitations to join p2p sessions; quitting p2p sessions; deleting p2p sessions or selected members of p2p sessions; and sharing and transferring files. | 05-13-2010 |
20120014515 | METHODS AND SYSTEMS FOR VISUAL VOICE CALLS - In an exemplary method, at least one telephony attribute associated with a voice call directed from a client communication subsystem to a voice network identifier is detected. Visual content that has been predefined as being associated with the at least one telephony attribute is identified. A request for the visual content is initiated in response to the detecting step. The visual content is received, in response to the initiating step, for display at the client communication subsystem. | 01-19-2012 |
Patent application number | Description | Published |
20090126365 | Method for starting a steam turbine installation - The invention relates to a method for starting a steam turbine installation which comprises at least one steam turbine and at least one steam-generating installation for generating steam for driving the steam turbines, the steam turbine installation having at least one casing component, which has an initial starting temperature of more than 250° C., the temperature of the steam and of the casing component being continually measured, and the casing component of the steam turbine installation being supplied with steam from the starting time point onwards. The starting temperature of the steam is lower than the temperature of the casing component and the temperature of the steam is increased with a start transient and the staring temperature is chosen such that the change in temperature per unit of time of the casing component lies below a predefined limit. The temperature of the casing component initially decreases, until a minimum is reached and then increases. | 05-21-2009 |
20090138211 | Method and Apparatus for Determination of the Life Consumption of Individual Components in a Fossil Fuelled Power Generating Installation, in Particular in a Gas and Steam Turbine Installation - There is described a method for prior determination of a life consumption of individual components in a fossil-fuelled power generating installation, with respect to a load cycling process to be carried out. An apparatus can be provided for prior determination of a life consumption of individual components in a fossil-fuelled power generating installation, with respect to a load cycling process to be carried out. Actual variables which characterize the state of the power generating installation before a load cycling process are determined. A driving gear of the power generating installation which creates the load cycling process is set in advance. The load cycle time is calculated based upon the driving gear and the characterizing variables. A predicted life consumption for at least one of the individual components for the selected driving gear is also calculated. | 05-28-2009 |
20090211259 | Method for Starting Up a Gas and Steam Turbine System - The invention relates to a method for starting a gas and steam turbine system which comprises a gas turbine system which comprises at least one gas turbine, in addition to at least one steam turbine system which comprises at least one steam turbine and at least one steam system. Heat produced by the working fluid and which is released in the gas turbine is guided to the steam system in order to produce steam which drives the steam turbine. According to the invention, during starting, the gas turbine is started prior to the steam turbine and the steam turbine is started in the presence of the first steam in the system and is impinged upon by said steam. | 08-27-2009 |
20090249788 | Method for Warming-Up a Steam Turbine - The invention relates to a method for heating a steam turbine comprising a high-pressure turbine section and a medium-pressure turbine section and/or a low-pressure turbine section. Said method is characterized by the essential aspect that the high-pressure turbine section is impinged upon by steam having relatively great conductivity while the medium-pressure turbine section or the low-pressure turbine section remains closed during said impingement following a cold start. As soon as the conductivity drops below a certain value, the medium-pressure turbine section or the low-pressure turbine section is also impinged upon by steam. | 10-08-2009 |
20090288415 | Method for Warming-Up a Steam Turbine - There is described a method for heating a steam turbine comprising a medium-pressure turbine section and/or a low-pressure turbine section, the discharge end of the medium-pressure turbine section being provided with a catchment device. Steam penetrating the medium-pressure turbine section during a starting process is retained at an outlet by means of a catchment device in such a way that the pressure of the steam increases in the medium-pressure turbine section. The steam that is discharged from the medium-pressure turbine section is retained, thus increasing the pressure and the temperature of the steam. Heat transfer from the steam to the thick-walled parts located on the medium pressure turbine section and the shaft of the medium-pressure turbine section is augmented, thus reducing the starting time of the steam turbine. | 11-26-2009 |
20100133756 | Shaft seal for steam turbines - A shaft seal for steam turbines is provided. The shaft seal steam barrier is supplied with a slight excess pressure. In order to avoid complex additional devices necessary for liquefying the water vapor once again, a condensation chamber, which is sealed from the surrounding air as well as from the steam barrier chamber with brush seals, is provided between the steam barrier chamber and the surrounding air. The condensation chamber is constructed in such a manner that the heat, developing in the interior thereof, is discharged to the outside. | 06-03-2010 |
20120174584 | POWER PLANT SYSTEM HAVING OVERLOAD CONTROL VALVE - A power plant system and a method for operating a power plant system are provided. An overload control valve is disposed in an overload line and can be actuated by means of a pressure regulator wherein the overload control valve opens before a diverting control valve opens the valve forming a bypass between the high-pressure steam inlet and the high-pressure steam outlet as soon as a target valve is exceeded. | 07-12-2012 |
20120251294 | Shaft Seal for Steam Turbines - A steam turbine with a shaft seal is provided. The shaft seal steam barrier is supplied with a slight excess pressure. In order to avoid complex additional devices necessary for liquefying the water vapor once again, a condensation chamber, which is sealed from the surrounding air as well as from the steam barrier chamber with brush seals, is provided between the steam barrier chamber and the surrounding air. The condensation chamber is constructed in such a manner that the heat, developing in the interior thereof, is discharged to the outside. | 10-04-2012 |
20140305132 | METHOD FOR STARTING UP A GAS AND STEAM TURBINE SYSTEM - A method for starting a gas and steam turbine system which includes a gas turbine system which includes at least one gas turbine, in addition to at least one steam turbine system which includes at least one steam turbine and at least one steam system is provided. Heat produced by the working fluid and which is released in the gas turbine is guided to the steam system in order to produce steam which drives the steam turbine. During starting, the gas turbine is started prior to the steam turbine and the steam turbine is started in the presence of the first steam in the system and is impinged upon by said steam. | 10-16-2014 |
Patent application number | Description | Published |
20090191060 | LUBRICATION HEATING SYSTEM AND WIND TURBINE INCORPORATING SAME - A wind turbine is provided having a gearbox containing a lubrication medium, a pump for circulating the lubrication medium. and a gearbox lubrication suction pipe for transporting the lubrication medium from the gearbox to the pump. A heater is in thermal connection to, at least a portion of, the gearbox lubrication suction pipe. This heater is used to heat the lubrication medium contained within the gearbox lubrication suction pipe to a temperature where damage to the pump is avoided. | 07-30-2009 |
20100129222 | WIND TURBINE DRIVE SHAFT CONNECTION ARRANGEMENT - A connection arrangement for connecting drive shafts of a wind turbine including a rotor having a rotor shaft and a hub, and a gearbox having a gearbox input shaft is provided. The connection arrangement includes a first shaft connection means having a recessed portion arranged at the rotor shaft symmetrically to the axis of the rotor shaft, a second shaft connection means having a protruding portion arranged symmetrically to the axis of the gearbox input shaft, wherein the protruding portion of the second shaft connection means engages with the recessed portion of the first shaft connection means, and a fixing means for fixing the protruding portion of the first shaft connection means at the recessed portion of the second shaft connection means. A frictionally engaged connection is provided. | 05-27-2010 |
20100329867 | DRIVETRAIN SYSTEM FOR A WIND TURBINE GENERATOR AND METHOD OF ASSEMBLING THE SAME - A drivetrain for a wind turbine includes a gearbox and a generator. The gear box includes a housing and an output shaft that is rotatably coupled within the housing, wherein the gearbox further includes at least one bearing positioned between the housing and the output shaft. The generator includes a stator coupled to the housing such that the stator is positioned radially outward from the housing, and a rotor coupled to the output shaft such that the rotor is positioned radially inward from the stator. | 12-30-2010 |
20110168494 | LUBRICATION OF WIND TURBINE GEARBOX DURING IDLING OR LOSS OF ELECTRIC GRID - A lubrication system for a wind turbine is provided. The system includes a supply subsystem for providing oil via an oil tank or a hydraulic accumulator to a gearbox of the wind turbine for lubrication during at least one of idling or loss of electric grid. The system also includes a control subsystem for controlling the flow in the lubrication system. | 07-14-2011 |
20110168495 | LUBRICATION OF FLUID TURBINE GEARBOX DURING IDLING OR LOSS OF ELECTRIC GRID - A lubrication system for a fluid turbine is provided. The system includes a supply subsystem for providing oil via an oil tank or a hydraulic accumulator to a gearbox of the fluid turbine for lubrication during at least one of idling or loss of electric grid. The system also includes a control subsystem for controlling the flow in the lubrication system. | 07-14-2011 |
20110269557 | System and method for connecting shafts of a wind turbine - The present disclosure relates to a plug shaft and/or a socket shaft for use in a shaft connection system of a wind turbine. The plug shaft includes a tapered plug end portion for engaging a tapered socket end portion in the shaft connection system. The socket shaft includes a tapered socket end portion for engaging a tapered plug end portion in the shaft connection system. The present disclosure also relates to a shaft connection system of a wind turbine. The shaft connection system includes a first shaft comprising a first tapered end portion and a second shaft comprising a second tapered end portion. | 11-03-2011 |
20120028754 | LIQUID EQUALIZED GEAR SYSTEM AND METHOD FOR USING SAME - A carrier for use in a planetary gear system. The carrier has a plurality of openings or slots offset from a midline thereof. The carrier includes alignment mechanisms positioned in each of the plurality of openings or slots to substantially align each planet gear about the midline of the carrier. The carrier may be used in a planetary gear system for use in a wind turbine. One aspect incorporates eccentric rings in the openings. Another aspect incorporates inserts in the slots. Each of the rings and inserts has openings that, when properly positioned, will substantially bisect the carrier midline. | 02-02-2012 |
Patent application number | Description | Published |
20090004368 | Systems and methods for curing a deposited layer on a substrate - Curing systems are provided that include a planar support surface for supporting a substrate having at least one layer deposited thereon, at least one curing device for curing the at least one deposited layer, and a control system for controlling the overall curing process. The curing device includes at least one laser, a lens module, and an optional modulator. During curing, the beam of light emitted from the laser may be directed onto the deposited layer by 1) controlling the position of an X-Y beam deflecting module to direct the focused beam of laser light onto a desired illumination area of the deposited layer; 2) controlling the position of the laser via an X-Y table, or 3) controlling the position of the substrate via an X-Y table. | 01-01-2009 |
20090314381 | SYSTEM AND METHOD FOR FILLING A SEEDCOAT WITH A LIQUID TO A SELECTED LEVEL - A fluid dispensing system includes a fluid dispensing pump interchangeably connected to a fluid dispensing pump manipulator that is capable of translating the fluid dispensing pump between two known positions along the Z-axis, and at least one open ended container, such as a seedcoat, disposed below the fluid dispensing pump for receiving fluid therefrom. The fluid dispensing system further includes a controller. The controller | 12-24-2009 |
20100001261 | Organic transistor having a non-planar semiconductor-insulating layer interface - Organic transistors having a nonplanar interface between the insulating layer and the semiconductor layer are provided, along with methods for manufacturing. | 01-07-2010 |
20100003021 | Systems and methods for curing deposited material using feedback control - Methods and systems are provided for optimally curing a deposited curable material film using a light source and feedback system for monitoring the degree of curing using detected optical properties of the film. Operational parameters of the light source (e.g., power) are adjusted by a control system in response to the detected optical properties of the film. The curing system includes at least one light source in optical communication with an uncured material, a detector for monitoring an optical property of the curing material, and a feedback system for controlling the light emitted from the light source in response to the detector. | 01-07-2010 |
Patent application number | Description | Published |
20100300993 | Modular utility rack - A rack has a frame and at least one shelf. The frame has a rear support that has a left side and a right side. The frame further includes a left support that is pivotably connected to the left side of the rear support and a right support that is pivotably connected to the right side of the rear support, the left and right supports having a plurality of horizontal bars. The shelf has a left side and a right side, with a first hooked connector provided on the left side of the shelf and a second hooked connector provided on the right side of the shelf. The first hooked connector removably connects the left side of the shelf to a horizontal bar on the left support, and the second hooked connector removably connects the right side of the shelf to a horizontal bar on the right support. | 12-02-2010 |
20110240571 | Modular utility rack - A rack has a frame and at least one shelf. The frame has a first rear support member and a second rear support member, with each support member having a left side and a right side, with the right side of the first rear support member pivotably connected to the left side of the second rear support member. The frame further includes a left support that is pivotably connected to the left side of the first rear support member and a right support that is pivotably connected to the right side of the second rear support member. The shelf has a left side and a right side, with a first hooked connector provided on the left side of the shelf and a second hooked connector provided on the right side of the shelf. The first hooked connector removably connects the left side of the shelf to a horizontal bar on the left support, and the second hooked connector removably connects the right side of the shelf to a horizontal bar on the right support. | 10-06-2011 |
20120216985 | HEATING AND COOLING APPARATUS - A portable air blowing appliance has a housing retaining a blower adapted when energized to create an airflow through and from the housing, and a heating element adapted when energized to impart heat to the airflow. A movable deflector selectively steers the airflow either though or not through the heating element. In the exemplary embodiment shown, the blower is, in combination, a motor-driven centrifugal blower rotatable about a blower axis to create the airflow, and a scroll surrounding the blower wheel and adapted to direct the airflow from the blower wheel forwardly from the housing. In this exemplary embodiment, the deflector is movable about a pivot axis perpendicular to the blower axis between a heating position wherein the airflow is steered through the heating element and a cooling position where the airflow is steered not through the heating element. | 08-30-2012 |
20120219434 | HEATING AND COOLING APPARATUS - As exemplified, a portable air blowing appliance includes a housing retaining an airflow-producing electric motor-driven blower. The blower is adapted when energized for operation in either a first or a different mode. An electric heating element is adapted when energized to expel heat. An electric switch enables energizing of the blower and the heating element to either cause operation of the blower in the first mode or to cause, simultaneously, operation of the blower in the different mode and heat expulsion by the heating element. The blower is adapted for higher airflow-producing efficacy during the first mode. The heating element is disposed to warm airflow from the blower during the different mode. | 08-30-2012 |
20130147163 | Foldable hand Cart - A hand cart has a frame having a left vertical member and right vertical member, each vertical member having a top end that is coupled to a handle bar, and a bottom end that has a pin extending therefrom. The hand cart also includes a left wheel assembly and a right wheel assembly, each wheel assembly having a tubular housing that receives a portion of a vertical member, and a wheel secured to the tubular housing, with each tubular housing having a spiral slot that receives the pin of the corresponding bottom end for movement within the slot. A carrier plate has a left seat and a right seat, each seat pivotably connected to a corresponding bottom end of a vertical member. | 06-13-2013 |
20130315727 | STACKABLE FAN - An air blowing system is disclosed having top and bottom air blowers that each includes a blower base and a blower housing tiltable relative thereto, and a coupling for enabling pivotable affixation of the top blower base to the bottom air blower, The air blowing system has at least first and second operational modes, whereby in the first operational mode the coupling does not affix the top blower base to the bottom air blower and the bottom and top air blowers are relatively independent, and in the second operational mode the coupling pivotably affixes the top blower base to the bottom air blower. | 11-28-2013 |
Patent application number | Description | Published |
20100249126 | PYRIMIDINE DERIVATIVES USED AS PI-3-KINASE INHIBITORS - Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases. | 09-30-2010 |
20120225859 | PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS - Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases. | 09-06-2012 |
Patent application number | Description | Published |
20090177985 | CAPTURING DATA FROM USER SELECTED PORTIONS OF A BUSINESS PROCESS AND TRANSFERRING CAPTURED DATA TO USER IDENTIFIED DESTINATIONS - A graphical user interface (GUI) displays a flow of activities of a business process, including any portion thereof from which capture of data is permitted. The GUI receives, in an operation, at least an indication of a business process portion from which data is to be captured (“sensor”), an identification of an endpoint to which captured data is to be transferred, and a type of the endpoint which identifies (through a mapping) a predetermined software. A sensor may be added any number of times (through a single GUI or though multiple GUIs) by repeatedly performing the operation. Also, a given sensor may be associated with multiple endpoints. Computer(s) executing the business process check whether or not a sensor is present, on execution of the business process portion, and if present, then execute the corresponding predetermined software(s) to transfer data from the sensor directly to the respective endpoint(s). | 07-09-2009 |
20090313256 | REUSE OF SHARED METADATA ACROSS APPLICATIONS VIA URL PROTOCOL - Techniques for facilitating the sharing of metadata. In one set of embodiments, a metadata document is referenced by a plurality of software applications as a URL, the URL comprising a protocol component identifying a specialized protocol name and a path component identifying a name and namespace of the metadata document. The specialized protocol name indicates that the metadata document is a shared document stored in a shared metadata repository. When an application in the plurality of software applications needs to access the metadata document, the URL is passed to a URL resolver configured to identify the shared metadata repository based on configuration information associated with the application. The metadata document is then retrieved from the shared metadata repository. Since many existing application framework components and standards are adapted to reference metadata documents as URLs, embodiments of the present invention facilitate metadata reuse with minimal or no code changes to the applications or their underlying framework. | 12-17-2009 |
Patent application number | Description | Published |
20100064781 | MULTI-WELL PLATE WITH TAILORED CHAMBERS - Systems, methods and multi-well plates comprising an array of wells for thermal treatment of chemical or biological samples are disclosed. Each of the wells comprises a bottom opening, an upper opening, inner side walls extending from the bottom opening to the upper opening, a protrusion extending from the inner side walls into the well with a first cross-sectional area and located at a height from the bottom opening which is smaller than the height from the upper opening. A sample chamber with a second cross-sectional area is formed between the bottom opening and the protrusion. An upper chamber with a third cross-sectional area is formed between the protrusion and the upper opening, and in which the first cross-sectional area is smaller than the third cross-sectional area and smaller than or equal to the second cross-sectional area. | 03-18-2010 |
20110189052 | System For The Analysis Of Liquid Samples - A system for the automated analysis of liquid samples having one or more processing units for reaction between the samples and one or more reagents to thereby obtain reaction products is disclosed. Disclosed also are a sample unit for supplying the samples to the one or more processing units; a reagent unit equipped with plural reagent vessels containing one or more reagents for mixing with the samples; a distribution unit for distributing fluids including the one or more reagents provided with plural distribution lines, at least some of which are connected to the reagent vessels and the one or more processing units; and at least one analytical unit for analyzing the samples based on the reaction products, in which the analytical unit may include at least one detector for detecting the reaction products. | 08-04-2011 |
20110189785 | PROCESSING UNITS AND METHODS FOR THE PROCESSING OF LIQUID SAMPLES - A microfluidic processing unit for the automated processing of liquid samples and method thereof are disclosed. In one embodiment, the unit comprises first and second main channels connected to a pump for generating a negative or positive pressure therein; a sample channel which supplies a liquid sample is connectable to a sample vessel containing the liquid sample, the sample channel communicates with the first main channel and is equipped with an on/off valve; one or more reagent channels for supplying one or more reagents, the reagent channels being connectable to reagent vessels containing reagents for reacting with the liquid samples, each of the reagent channels communicating with the first or second main channel and being equipped with an on/off valve; and a reaction chamber for reacting a sample and reagent, the reaction chamber being connected to the first and second main channels via at least one on/off valve. | 08-04-2011 |
20110250695 | METHOD, STRUCTURE, DEVICE, KIT AND SYSTEM FOR THE AUTOMATED ANALYSIS OF LIQUID SAMPLES - A method for the automated analysis of liquid samples using at least one microfluidic structure is disclosed as well as microfluidic structures, a device having at least one of the microfluidic structures, a kit and a system including such microfluidic device. In one embodiment, the method may comprise: transferring said sample into a first fluid reservoir which is in fluid communication with a second fluid reservoir by a flow channel; spinning said microfluidic structure so as to transport said sample into one or more dead-end recesses or chambers; transferring a control fluid into the structure which generates a barrier to flow and diffusion of said sample contained in said one or more dead-end recesses or chambers; and analyzing said sample contained in said one or more dead-end recesses or chambers. | 10-13-2011 |
20140329249 | SELECTIVE RELEASE OF SUB-GROUP OF BIOLOGICAL UNITS - A method of individually releasing from an entity one or more members of a sub-group of biological units included in a heterogeneous group of biological units is provided. The method includes binding the group of biological units including the sub-group of biological units to the entity via a linker. Following binding, the location of the one or more members on the entity is determined. Once the location is determined, a localized physical pulse is applied to the one or more members. The localized physical pulse individually releases the one or more members from the entity by dissociating the linker. | 11-06-2014 |
20140360269 | ACCELERATION SENSITIVE INDICATOR - An acceleration sensitive indicator for indicating a centrifugation status of a biological sample, a sample container comprising the indicator, a centrifuge for centrifuging samples and an analytical system for analyzing centrifuged samples are disclosed. The indicator comprises at least one closed chamber, formed between two opposite surfaces, that comprises an indication zone that comprises at least two fluid transfer zones or at least one particle transfer zone. The at least one fluid transfer zone comprises a solid carrier phase and a fluid stabilized in the solid carrier phase or at least one non-stabilized non-Newtonian fluid having thixotropic and/or shear thinning properties. The at least one particle transfer zone comprises a particle stabilizing fluid comprising stabilized dispersed particles. The fluid or particles have a distribution with respect to the indication zone changeable upon application of a g-force above a threshold value, the change of distribution indicating the centrifugation status. | 12-11-2014 |
20150017681 | DEVICE AND METHOD FOR BIOLOGICAL SAMPLE COLLECTION AND INSPECTION - A device is described including a lid, a collection portion support, and a collection portion with a surface for receiving a biological sample, the lid includes a window and a window holder, the surface defines a first plane, the collection portion includes a first, a second, and a third position markers, each position marker indicates a center point marker, the center points define a second plane that has a line of intersection with the first plane, the device has an interior volume defined partially by the collection portion support, the collection portion, the window, and the window holder, the window allows visual inspection of the position markers, the collection portion support has a fluid inlet and a fluid outlet with a fluid path from the fluid inlet to the fluid outlet via the interior volume. | 01-15-2015 |
Patent application number | Description | Published |
20080204092 | Cicuit Arrangement, in Particular Phase-Locked Loop, as Well as Corresponding Method - In order to further develop a circuit arrangement ( | 08-28-2008 |
20090072895 | SIGNAL PROCESSING WITH INTERFERENCE COMPENSATION - A processor reduces periodic interference signal components in an input signal to obtain a desired signal. The desired signal has a predefined characteristic during an interval of time. First, an interference-representing signal (S | 03-19-2009 |
20090116373 | SIGNAL PROCESSOR HAVING A SAMPLING ARRANGEMENT - In a signal processor, a sampling arrangement (SH | 05-07-2009 |
20090267814 | CIRCUIT ARRANGEMENT, L[OCAL] I[NTERCONNECTED] NE[TWORK] COMPRISING SUCH CIRCUIT ARRANGEMENT AS WELL AS METHOD FOR PROCESSING INPUT SIGNALS OF THE LIN - Circuit arrangement, L[ocal]I[nterconnected]N[etwork] comprising such circuit arrangement as well as method for processing input signals of the LIN In order to further develop a circuit arrangement ( | 10-29-2009 |
20120293234 | PULSE SHAPER CIRCUIT WITH REDUCED ELECTROMAGNETIC EMISSION - In one embodiment, a circuit-based apparatus that operates on an input data stream includes delay-line circuitry that characterizes the input data stream, modified over time. A plurality of integrators provide a plurality of integrated signals in response to the delay-line circuitry, and a plurality of weighting amplifiers amplify the plurality of integrated signals by a plurality of respective time-varying weighting factors to provide weighted signals. A signal-combining circuit combines the weighted signals. The circuit-based apparatus also includes a plurality of parallel signal-processing circuit paths that couple the weighted signals to the signal-combining circuit. By combining the weighted signals from the parallel signal-processing circuit paths, the signal-combining circuit provides a signal representative of the input data stream. | 11-22-2012 |
Patent application number | Description | Published |
20090282838 | METHOD, APPARATUS, AND SYSTEM FOR COOLING AN OBJECT - A method for cooling an object includes coupling a cooling device to the object, wherein the cooling device includes at least one thermoacoustic engine and a plurality of gas diodes, generating acoustic power with the thermoacoustic engine, channeling acoustic oscillations of a fluid through the gas diodes, and transferring the heat produced by the object to the fluid to facilitate moving the heat away from the object. | 11-19-2009 |
20100010642 | METHOD AND SYSTEM FOR SAFETY MONITORED TERMINAL BLOCK - A method, apparatus, and system for controlling a process are provided. The control device apparatus includes an input section configured to receive input signals from a controlled process, a first output section communicatively coupled to the input section wherein the first output section is configured to transmit the received input signals to a controller, and a second output section communicatively coupled to the controller, the second output section is configured to transmit control signals from the controller to the controlled process. The apparatus further includes a safety logic block communicatively coupled to the input section in parallel with the received input signals that are transmitted to the controller, the safety logic block is configured to generate a safety output signal using the received input signals, the safety logic block is further configured to transmit the safety output signal to the controlled process independent of the control signals. | 01-14-2010 |
Patent application number | Description | Published |
20090062835 | CATHETER HAVING AN IMPROVED DISTAL TIP - An elongated balloon catheter having a distal tip member on the distal end of the catheter and having a sleeve surrounding and secured at least to the proximal end of the distal tip member. | 03-05-2009 |
20090247946 | CATHETER WITH A MULTILAYERED SHAFT SECTION HAVING A POLYIMIDE LAYER - A catheter having an multilayered shaft section with a first layer formed of a polyimide first material and a second layer formed of a second material. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. However, in alternative embodiments, a thermoplastic polyimide is used. The thermoset polyimide has a very high glass transition temperature (Tg) of approximately 400° C. (as measured by differential scanning calorimetry), and excellent dimensional stability at the processing temperature of polyamides commonly used in catheter components. As a result, during formation and assembly of the catheter, production of a thin polyimide layer with controlled dimensions is facilitated. The polyimide has a high modulus and provides a thin walled yet highly pushable shaft section, while the second layer provides kink resistance. In one embodiment, the second material is selected from the group consisting of a polyamide material and a polyurethane material. | 10-01-2009 |
20120083732 | CATHETER WITH A POLYMIDE DISTAL TIP - A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material. | 04-05-2012 |
20130178796 | CATHETER WITH A POLYMIDE DISTAL TIP - A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material. | 07-11-2013 |
20140277361 | METHODS AND APPARATUS FOR LUMINAL STENTING - Stent delivery systems and methods of use are provided. The systems can include a catheter, a core member, and engagement member, and a stent. The catheter can have a inner wall. The core member can extend within the catheter and having a distal segment. The engagement member can be attached to the distal segment. Further, the stent can be positioned within the catheter and extend over the engagement member. The stent can have an axial length that is greater than an axial length of the engagement member. The engagement member can have an expanded state in which the engagement member presses the stent against the catheter inner wall for engaging the stent to move the stent along with the core member relative to the catheter. | 09-18-2014 |
20150088060 | COMPUTER CONTROLLED STEERABLE TIP GUIDE CATHETER - A catheter system is provided. The system includes a catheter having an elongated flexible body and one or more electroactive polymer actuators disposed along the elongated flexible body. The electroactive polymer actuators are adapted to cause a change in configuration of the elongated flexible body. The system also includes a controller adapted to transmit the control signal to the electroactive polymer actuators. The controller includes a memory storing a plurality of control signals corresponding to a plurality of predetermined configurations of the catheter and a user-interface coupled to the memory. The user-interface is configured to select one or more configurations from the plurality of predetermined configurations in response to user input. | 03-26-2015 |